-
1
-
-
0020596551
-
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
-
Barre-Sinoussi, F. et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 220, 868-871 (1983).
-
(1983)
Science
, vol.220
, pp. 868-871
-
-
Barre-Sinoussi, F.1
-
2
-
-
0021261510
-
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS
-
Gallo, R. C. et al. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science 224, 500-503 (1984).
-
(1984)
Science
, vol.224
, pp. 500-503
-
-
Gallo, R.C.1
-
3
-
-
0021237243
-
Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS
-
Popovic, M., Sarngadharan, M. G., Read, E. & Gallo, R. C. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 224, 497-500 (1984).
-
(1984)
Science
, vol.224
, pp. 497-500
-
-
Popovic, M.1
Sarngadharan, M.G.2
Read, E.3
Gallo, R.C.4
-
4
-
-
0021234845
-
Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS
-
Sarngadharan, M. G., Popovic, M., Bruch, L., Schupbach, J. & Gallo, R. C. Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS. Science 224, 506-508 (1984).
-
(1984)
Science
, vol.224
, pp. 506-508
-
-
Sarngadharan, M.G.1
Popovic, M.2
Bruch, L.3
Schupbach, J.4
Gallo, R.C.5
-
5
-
-
0021281132
-
Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS
-
Schupbach, J. et al. Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS. Science 224, 503-505 (1984).
-
(1984)
Science
, vol.224
, pp. 503-505
-
-
Schupbach, J.1
-
6
-
-
43749123908
-
25 years of HIV
-
Fauci, A. S. 25 years of HIV. Nature 453, 289-290 (2008).
-
(2008)
Nature
, vol.453
, pp. 289-290
-
-
Fauci, A.S.1
-
7
-
-
0034732201
-
Viral load and heterosexual transmission of human immunodeficiency virus type 1
-
Quinn, T. C. et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. N. Engl. J. Med. 342, 921-929 (2000).
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 921-929
-
-
Quinn, T.C.1
-
8
-
-
19144365910
-
Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group
-
Mascola, J. R. et al. Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Evaluation Group. J. Infect. Dis. 173, 340-348 (1996).
-
(1996)
J. Infect. Dis
, vol.173
, pp. 340-348
-
-
Mascola, J.R.1
-
9
-
-
0028917784
-
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
-
Moore, J. P. et al. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J. Virol. 69, 101-109 (1995).
-
(1995)
J. Virol
, vol.69
, pp. 101-109
-
-
Moore, J.P.1
-
10
-
-
13944254982
-
Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
-
Flynn, N. M. et al. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J. Infect. Dis. 191, 654-665 (2005).
-
(2005)
J. Infect. Dis
, vol.191
, pp. 654-665
-
-
Flynn, N.M.1
-
11
-
-
33845433434
-
Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
-
Pitisuttithum, P. et al. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J. Infect. Dis. 194, 1661-1671 (2006).
-
(2006)
J. Infect. Dis
, vol.194
, pp. 1661-1671
-
-
Pitisuttithum, P.1
-
12
-
-
43949099690
-
Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults
-
Priddy, F. H. et al. Safety and immunogenicity of a replication-incompetent adenovirus type 5 HIV-1 clade B gag/pol/nef vaccine in healthy adults. Clin. Infect. Dis. 46, 1769-1781 (2008).
-
(2008)
Clin. Infect. Dis
, vol.46
, pp. 1769-1781
-
-
Priddy, F.H.1
-
13
-
-
84945513769
-
-
Fauci, A. S. The release of new data from the HVTN 502 (STEP) HIV vaccine study. NIH News 〈http://www3.niaid.nih.gov/about/directors/news/ step_11707.htm〉 (2007). These data demonstrate that a homologous rAd5-Gag/Pol/Nef vaccine regimen did not protect against HIV-1 in humans and may have increased risk of HIV-1 acquisition in individuals with pre-existing Ad5-specific neutralizing antibodies.
-
Fauci, A. S. The release of new data from the HVTN 502 (STEP) HIV vaccine study. NIH News 〈http://www3.niaid.nih.gov/about/directors/news/ step_11707.htm〉 (2007). These data demonstrate that a homologous rAd5-Gag/Pol/Nef vaccine regimen did not protect against HIV-1 in humans and may have increased risk of HIV-1 acquisition in individuals with pre-existing Ad5-specific neutralizing antibodies.
-
-
-
-
14
-
-
0037189323
-
Diversity considerations in HIV-1 vaccine selection
-
Gaschen, B. et al. Diversity considerations in HIV-1 vaccine selection. Science 296, 2354-2360 (2002).
-
(2002)
Science
, vol.296
, pp. 2354-2360
-
-
Gaschen, B.1
-
15
-
-
0035377540
-
Immune control of HIV: The obstacles of HLA and viral diversity
-
Walker, B. D. & Korber, B. T. Immune control of HIV: the obstacles of HLA and viral diversity. Nature Immunol. 2, 473-475 (2001).
-
(2001)
Nature Immunol
, vol.2
, pp. 473-475
-
-
Walker, B.D.1
Korber, B.T.2
-
16
-
-
38049094546
-
Antibody-based HIV-1 vaccines: Recent developments and future directions
-
Montefiori, D., Sattentau, Q., Flores, J., Esparza, J. & Mascola, J. Antibody-based HIV-1 vaccines: recent developments and future directions. PLoS Med. 4, e348 (2007).
-
(2007)
PLoS Med
, vol.4
-
-
Montefiori, D.1
Sattentau, Q.2
Flores, J.3
Esparza, J.4
Mascola, J.5
-
17
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong, P. D. et al. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393, 648-659 (1998).
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
-
18
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt, R. et al. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 393, 705-711 (1998).
-
(1998)
Nature
, vol.393
, pp. 705-711
-
-
Wyatt, R.1
-
19
-
-
13844302894
-
Structure of an unliganded simian immunodeficiency virus gp120 core
-
Chen, B. et al. Structure of an unliganded simian immunodeficiency virus gp120 core. Nature 433, 834-841 (2005).
-
(2005)
Nature
, vol.433
, pp. 834-841
-
-
Chen, B.1
-
20
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
Wei, X. et al. Antibody neutralization and escape by HIV-1. Nature 422, 307-312 (2003).
-
(2003)
Nature
, vol.422
, pp. 307-312
-
-
Wei, X.1
-
21
-
-
0037389643
-
Rapid evolution of the neutralizing antibody response to HIV type 1 infection
-
Richman, D. D., Wrin, T., Little, S. J. & Petropoulos, C. J. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc. Natl Acad. Sci. USA 100, 4144-4149 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 4144-4149
-
-
Richman, D.D.1
Wrin, T.2
Little, S.J.3
Petropoulos, C.J.4
-
22
-
-
34948854718
-
Broad HIV-1 neutralization mediated by CD4-binding site antibodies
-
Li, Y. et al. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nature Med. 13, 1032-1034 (2007).
-
(2007)
Nature Med
, vol.13
, pp. 1032-1034
-
-
Li, Y.1
-
23
-
-
33847101745
-
Structural definition of a conserved neutralization epitope on HIV-1 gp120
-
Zhou, T. et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 445, 732-737 (2007).
-
(2007)
Nature
, vol.445
, pp. 732-737
-
-
Zhou, T.1
-
24
-
-
21344434534
-
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
-
Haynes, B. F. et al. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science 308, 1906-1908 (2005).
-
(2005)
Science
, vol.308
, pp. 1906-1908
-
-
Haynes, B.F.1
-
25
-
-
37849000389
-
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
-
Sun, Z. Y. et al. HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity 28, 52-63 (2008).
-
(2008)
Immunity
, vol.28
, pp. 52-63
-
-
Sun, Z.Y.1
-
26
-
-
41649090223
-
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
-
Frey, G. et al. A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies. Proc. Natl Acad. Sci. USA 105, 3739-3744 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3739-3744
-
-
Frey, G.1
-
27
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
Baba, T. W. et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nature Med. 6, 200-206 (2000).
-
(2000)
Nature Med
, vol.6
, pp. 200-206
-
-
Baba, T.W.1
-
28
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola, J. R. et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nature Med. 6, 207-210 (2000).
-
(2000)
Nature Med
, vol.6
, pp. 207-210
-
-
Mascola, J.R.1
-
29
-
-
0027979037
-
+ T cells with a predominant V beta usage during the primary immune response to HIV
-
+ T cells with a predominant V beta usage during the primary immune response to HIV. Nature 370, 463-467 (1994).
-
(1994)
Nature
, vol.370
, pp. 463-467
-
-
Pantaleo, G.1
-
30
-
-
0028337166
-
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
-
Koup, R. A. et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68, 4650-4655 (1994).
-
(1994)
J. Virol
, vol.68
, pp. 4650-4655
-
-
Koup, R.A.1
-
31
-
-
0028041344
-
+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
-
+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol. 68, 6103-6110 (1994).
-
(1994)
J. Virol
, vol.68
, pp. 6103-6110
-
-
Borrow, P.1
Lewicki, H.2
Hahn, B.H.3
Shaw, G.M.4
Oldstone, M.B.5
-
32
-
-
0030831656
-
Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection
-
Musey, L. et al. Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection. N. Engl. J. Med. 337, 1267-1274 (1997).
-
(1997)
N. Engl. J. Med
, vol.337
, pp. 1267-1274
-
-
Musey, L.1
-
33
-
-
10644267588
-
Dominant influence of HLA-B in mediating the potential coevolution of HIV and HLA
-
Kiepiela, P. et al. Dominant influence of HLA-B in mediating the potential coevolution of HIV and HLA. Nature 432, 769-775 (2004).
-
(2004)
Nature
, vol.432
, pp. 769-775
-
-
Kiepiela, P.1
-
34
-
-
33846101731
-
+ T-cell responses to different HIV proteins have discordant associations with viral load
-
+ T-cell responses to different HIV proteins have discordant associations with viral load. Nature Med. 13, 46-53 (2007).
-
(2007)
Nature Med
, vol.13
, pp. 46-53
-
-
Kiepiela, P.1
-
35
-
-
0033524838
-
+ lymphocytes
-
+ lymphocytes. Science 283, 857-860 (1999).
-
(1999)
Science
, vol.283
, pp. 857-860
-
-
Schmitz, J.E.1
-
36
-
-
0033559648
-
+ T cell depletion in simian immunodeficiency virus-infected macaques
-
+ T cell depletion in simian immunodeficiency virus-infected macaques. J. Exp. Med. 189, 991-998 (1999).
-
(1999)
J. Exp. Med
, vol.189
, pp. 991-998
-
-
Jin, X.1
-
37
-
-
0025827529
-
Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
-
Phillips, R. E. et al. Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354, 453-459 (1991).
-
(1991)
Nature
, vol.354
, pp. 453-459
-
-
Phillips, R.E.1
-
38
-
-
0034699512
-
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
-
Allen, T. M. et al. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 407, 386-390 (2000).
-
(2000)
Nature
, vol.407
, pp. 386-390
-
-
Allen, T.M.1
-
39
-
-
0037122796
-
Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
-
Barouch, D. H. et al. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415, 335-339 (2002).
-
(2002)
Nature
, vol.415
, pp. 335-339
-
-
Barouch, D.H.1
-
40
-
-
33646686040
-
+ T cells
-
+ T cells. Blood 107, 4781-4789 (2006).
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
-
41
-
-
34250327922
-
+ T cell responses
-
+ T cell responses. J. Exp. Med. 204, 1405-1416 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 1405-1416
-
-
Precopio, M.L.1
-
42
-
-
34250303350
-
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
-
Darrah, P. A. et al. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nature Med. 13, 843-850 (2007).
-
(2007)
Nature Med
, vol.13
, pp. 843-850
-
-
Darrah, P.A.1
-
43
-
-
44949100369
-
Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
-
Watkins, D. I., Burton, D. R., Kallas, E. G., Moore, J. P. & Koff, W. C. Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nature Med. 14, 617-621 (2008).
-
(2008)
Nature Med
, vol.14
, pp. 617-621
-
-
Watkins, D.I.1
Burton, D.R.2
Kallas, E.G.3
Moore, J.P.4
Koff, W.C.5
-
44
-
-
41149096579
-
T-cell quality in memory and protection: Implications for vaccine design
-
Seder, R. A., Darrah, P. A. & Roederer, M. T-cell quality in memory and protection: implications for vaccine design. Nature Rev. Immunol. 8, 247-258 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 247-258
-
-
Seder, R.A.1
Darrah, P.A.2
Roederer, M.3
-
45
-
-
0030913366
-
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
-
Chun, T. W. et al. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387, 183-188 (1997).
-
(1997)
Nature
, vol.387
, pp. 183-188
-
-
Chun, T.W.1
-
46
-
-
0032555117
-
+ T cells during primary HIV-1 infection
-
+ T cells during primary HIV-1 infection. Proc. Natl Acad. Sci. USA 95, 8869-8873 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 8869-8873
-
-
Chun, T.W.1
-
47
-
-
0037007670
-
+ T cells
-
+ T cells. Nature 417, 95-98 (2002).
-
(2002)
Nature
, vol.417
, pp. 95-98
-
-
Douek, D.C.1
-
48
-
-
0032540418
-
+ T cell depletion and viral replication in SIV infection
-
+ T cell depletion and viral replication in SIV infection. Science 280, 427-431 (1998).
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.S.1
-
49
-
-
17844374605
-
+ T cells in multiple tissues during acute SIV infection
-
+ T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097 (2005).
-
(2005)
Nature
, vol.434
, pp. 1093-1097
-
-
Mattapallil, J.J.1
-
50
-
-
17844376742
-
+ T cells
-
+ T cells. Nature 434, 1148-1152 (2005).
-
(2005)
Nature
, vol.434
, pp. 1148-1152
-
-
Li, Q.1
-
51
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley, J. M. et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Med. 12, 1365-1371 (2006).
-
(2006)
Nature Med
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
-
52
-
-
33745015013
-
Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge
-
Mattapallil, J. J. et al. Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge. J. Exp. Med. 203, 1533-1541 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1533-1541
-
-
Mattapallil, J.J.1
-
53
-
-
0027043276
-
Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
-
Daniel, M. D., Kirchhoff, F., Czajak, S. C., Sehgal, P. K. & Desrosiers, R. C. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258, 1938-1941 (1992).
-
(1992)
Science
, vol.258
, pp. 1938-1941
-
-
Daniel, M.D.1
Kirchhoff, F.2
Czajak, S.C.3
Sehgal, P.K.4
Desrosiers, R.C.5
-
54
-
-
0029951823
-
Vaccine protection by a triple deletion mutant of simian immunodeficiency virus
-
Wyand, M. S., Manson, K. H., Garcia-Moll, M., Montefiori, D. & Desrosiers, R. C. Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J. Virol. 70, 3724-3733 (1996).
-
(1996)
J. Virol
, vol.70
, pp. 3724-3733
-
-
Wyand, M.S.1
Manson, K.H.2
Garcia-Moll, M.3
Montefiori, D.4
Desrosiers, R.C.5
-
55
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort
-
Learmont, J. C. et al. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340, 1715-1722 (1999).
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1715-1722
-
-
Learmont, J.C.1
-
56
-
-
0028944667
-
Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
-
Baba, T. W. et al. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267, 1820-1825 (1995).
-
(1995)
Science
, vol.267
, pp. 1820-1825
-
-
Baba, T.W.1
-
57
-
-
0032905068
-
Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques
-
Baba, T. W. et al. Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nature Med. 5, 194-203 (1999).
-
(1999)
Nature Med
, vol.5
, pp. 194-203
-
-
Baba, T.W.1
-
58
-
-
0024844908
-
A formalin-inactivated whole SIV vaccine confers protection in macaques
-
Murphey-Corb, M. et al. A formalin-inactivated whole SIV vaccine confers protection in macaques. Science 246, 1293-1297 (1989).
-
(1989)
Science
, vol.246
, pp. 1293-1297
-
-
Murphey-Corb, M.1
-
59
-
-
27244443079
-
+ T cell responses in nonhuman primates
-
+ T cell responses in nonhuman primates. Proc. Natl Acad. Sci. USA 102, 15190-15194 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15190-15194
-
-
Wille-Reece, U.1
-
60
-
-
33646697743
-
Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates
-
Wille-Reece, U. et al. Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates. J. Exp. Med. 203, 1249-1258 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1249-1258
-
-
Wille-Reece, U.1
-
61
-
-
0038664390
-
Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
-
Casimiro, D. R. et al. Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J. Virol. 77, 6305-6313 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 6305-6313
-
-
Casimiro, D.R.1
-
62
-
-
33845412550
-
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine
-
Graham, B. S. et al. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine. J. Infect. Dis. 194, 1650-1660 (2006).
-
(2006)
J. Infect. Dis
, vol.194
, pp. 1650-1660
-
-
Graham, B.S.1
-
63
-
-
0033766645
-
Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination
-
Barouch, D. H. et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 290, 486-492 (2000).
-
(2000)
Science
, vol.290
, pp. 486-492
-
-
Barouch, D.H.1
-
64
-
-
34249689699
-
Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques
-
Chong, S. Y. et al. Comparative ability of plasmid IL-12 and IL-15 to enhance cellular and humoral immune responses elicited by a SIVgag plasmid DNA vaccine and alter disease progression following SHIV(89.6P) challenge in rhesus macaques. Vaccine 25, 4967-4982 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 4967-4982
-
-
Chong, S.Y.1
-
65
-
-
34248382494
-
Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques
-
Luckay, A. et al. Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques. J. Virol. 81, 5257-5269 (2007).
-
(2007)
J. Virol
, vol.81
, pp. 5257-5269
-
-
Luckay, A.1
-
66
-
-
43949114521
-
Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation
-
Liu, J., Kjeken, R., Mathiesen, I. & Barouch, D. H. Recruitment of antigen-presenting cells to the site of inoculation and augmentation of human immunodeficiency virus type 1 DNA vaccine immunogenicity by in vivo electroporation. J. Virol. 82, 5643-5649 (2008).
-
(2008)
J. Virol
, vol.82
, pp. 5643-5649
-
-
Liu, J.1
Kjeken, R.2
Mathiesen, I.3
Barouch, D.H.4
-
67
-
-
0037122719
-
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity
-
Shiver, J. W. et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 415, 331-335 (2002).
-
(2002)
Nature
, vol.415
, pp. 331-335
-
-
Shiver, J.W.1
-
68
-
-
33845439080
-
Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector
-
Catanzaro, A. T. et al. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. J. Infect. Dis. 194, 1638-1649 (2006).
-
(2006)
J. Infect. Dis
, vol.194
, pp. 1638-1649
-
-
Catanzaro, A.T.1
-
69
-
-
0035815437
-
Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
-
Amara, R. R. et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 292, 69-74 (2001).
-
(2001)
Science
, vol.292
, pp. 69-74
-
-
Amara, R.R.1
-
70
-
-
38749132973
-
An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
-
Harari, A. et al. An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses. J. Exp. Med. 205, 63-77 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 63-77
-
-
Harari, A.1
-
71
-
-
1542299092
-
Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors
-
Shiver, J. W. & Emini, E. A. Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors. Annu. Rev. Med. 55, 355-372 (2004).
-
(2004)
Annu. Rev. Med
, vol.55
, pp. 355-372
-
-
Shiver, J.W.1
Emini, E.A.2
-
72
-
-
29244455769
-
-
MAC239 challenges in rhesus monkeys.
-
MAC239 challenges in rhesus monkeys.
-
-
-
-
73
-
-
0037321597
-
Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication
-
Mothe, B. R. et al. Expression of the major histocompatibility complex class I molecule Mamu-A*01 is associated with control of simian immunodeficiency virus SIVmac239 replication. J. Virol. 77, 2736-2740 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 2736-2740
-
-
Mothe, B.R.1
-
74
-
-
0036133208
-
ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency
-
Pal, R. et al. ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency. J. Virol. 76, 292-302 (2002).
-
(2002)
J. Virol
, vol.76
, pp. 292-302
-
-
Pal, R.1
-
75
-
-
0036882075
-
Mamu-A*01 allele-mediated attenuation of disease progression in simian-human immunodeficiency virus infection
-
Zhang, Z. Q. et al. Mamu-A*01 allele-mediated attenuation of disease progression in simian-human immunodeficiency virus infection. J. Virol. 76, 12845-12854 (2002).
-
(2002)
J. Virol
, vol.76
, pp. 12845-12854
-
-
Zhang, Z.Q.1
-
76
-
-
33744902339
-
Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239
-
Wilson, N. A. et al. Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239. J. Virol. 80, 5875-5885 (2006).
-
(2006)
J. Virol
, vol.80
, pp. 5875-5885
-
-
Wilson, N.A.1
-
77
-
-
33744990609
-
+ central memory T cells and survival in vaccinated SIV-challenged monkeys
-
+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science 312, 1530-1533 (2006).
-
(2006)
Science
, vol.312
, pp. 1530-1533
-
-
Letvin, N.L.1
-
78
-
-
0037771077
-
Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: Efficient human cell infection and bypass of preexisting adenovirus immunity
-
Vogels, R. et al. Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity. J. Virol. 77, 8263-8271 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 8263-8271
-
-
Vogels, R.1
-
79
-
-
34247585475
-
Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D
-
Abbink, P. et al. Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. J. Virol. 81, 4654-4663 (2007).
-
(2007)
J. Virol
, vol.81
, pp. 4654-4663
-
-
Abbink, P.1
-
80
-
-
34247623684
-
Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa
-
Thorner, A. R. et al. Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa. J. Clin. Microbiol. 44, 3781-3783 (2006).
-
(2006)
J. Clin. Microbiol
, vol.44
, pp. 3781-3783
-
-
Thorner, A.R.1
-
81
-
-
2942562284
-
Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector
-
Kostense, S. et al. Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector. AIDS 18, 1213-1216 (2004).
-
(2004)
AIDS
, vol.18
, pp. 1213-1216
-
-
Kostense, S.1
-
82
-
-
48249134364
-
-
Fauci, A. S. et al. HIV vaccine research: the way forward. Science 321, 530-532 (2008). This perspective describes revised NIH research priorities for HIV-1 vaccine research.
-
Fauci, A. S. et al. HIV vaccine research: the way forward. Science 321, 530-532 (2008). This perspective describes revised NIH research priorities for HIV-1 vaccine research.
-
-
-
-
83
-
-
34247201441
-
Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine
-
Catanzaro, A. T. et al. Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine. Vaccine 25, 4085-4092 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 4085-4092
-
-
Catanzaro, A.T.1
-
84
-
-
84945503484
-
NIAID will not move forward with the PAVE 100 HIV vaccine trial
-
Fauci, A. S. NIAID will not move forward with the PAVE 100 HIV vaccine trial. NIH News 〈http://www3.niaid.nih.gov/news/newsreleases/2008/ pave100.htm〉 (2008).
-
(2008)
NIH News
-
-
Fauci, A.S.1
-
85
-
-
2442611810
-
Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity
-
Barouch, D. H. et al. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. J. Immunol. 172, 6290-6297 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 6290-6297
-
-
Barouch, D.H.1
-
86
-
-
33646586362
-
Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity
-
Roberts, D. M. et al. Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature 441, 239-243 (2006).
-
(2006)
Nature
, vol.441
, pp. 239-243
-
-
Roberts, D.M.1
-
87
-
-
0035164962
-
Replication-defective vector based on a chimpanzee adenovirus
-
Farina, S. F. et al. Replication-defective vector based on a chimpanzee adenovirus. J. Virol. 75, 11603-11613 (2001).
-
(2001)
J. Virol
, vol.75
, pp. 11603-11613
-
-
Farina, S.F.1
-
88
-
-
0037310512
-
A simian replication-defective adenoviral recombinant vaccine to HIV-1 gag
-
Fitzgerald, J. C. et al. A simian replication-defective adenoviral recombinant vaccine to HIV-1 gag. J. Immunol. 170, 1416-1422 (2003).
-
(2003)
J. Immunol
, vol.170
, pp. 1416-1422
-
-
Fitzgerald, J.C.1
-
89
-
-
43249127622
-
Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys
-
Liu, J. et al. Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys. J. Virol. 82, 4844-4852 (2008).
-
(2008)
J. Virol
, vol.82
, pp. 4844-4852
-
-
Liu, J.1
-
90
-
-
84945514478
-
-
Barouch, D. H. Novel adenovirus vector-based vaccines for HIV-1. Keystone Symposia on HIV Vaccines, Banff, Canada. Abstract X7 009, page 60 (Keystone Symposia, 27 March-1 April 2008).
-
Barouch, D. H. Novel adenovirus vector-based vaccines for HIV-1. Keystone Symposia on HIV Vaccines, Banff, Canada. Abstract X7 009, page 60 (Keystone Symposia, 27 March-1 April 2008).
-
-
-
-
91
-
-
33746689169
-
A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses
-
Liao, H. X. et al. A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology 353, 268-282 (2006).
-
(2006)
Virology
, vol.353
, pp. 268-282
-
-
Liao, H.X.1
-
92
-
-
33745771090
-
Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen
-
Weaver, E. A. et al. Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. J. Virol. 80, 6745-6756 (2006).
-
(2006)
J. Virol
, vol.80
, pp. 6745-6756
-
-
Weaver, E.A.1
-
93
-
-
33846111016
-
-
Fischer, W. et al. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature Med. 13, 100-106 (2007). This manuscript proposes the use of polyvalent 'mosaic' antigens to improve immunologic coverage of global HIV-1 diversity.
-
Fischer, W. et al. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature Med. 13, 100-106 (2007). This manuscript proposes the use of polyvalent 'mosaic' antigens to improve immunologic coverage of global HIV-1 diversity.
-
-
-
|