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Volumn 7, Issue 12, 2000, Pages 1011-1018

Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiation

Author keywords

Lung radioprotection; MnSOD; Plasmid liposomes

Indexed keywords

BETA GALACTOSIDASE; INTERLEUKIN 1; LIPOSOME; MACROPHAGE INFLAMMATORY PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PLASMID DNA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TUMOR NECROSIS FACTOR ALPHA;

EID: 0034131278     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301207     Document Type: Article
Times cited : (115)

References (32)
  • 1
    • 0031887093 scopus 로고    scopus 로고
    • Prevention of late effects of irradiation lung damage by MnSOD gene therapy
    • Epperly MW et al. Prevention of late effects of irradiation lung damage by MnSOD gene therapy. Gene Therapy 1998; 5: 196-208.
    • (1998) Gene Therapy , vol.5 , pp. 196-208
    • Epperly, M.W.1
  • 2
    • 0032897928 scopus 로고    scopus 로고
    • Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis
    • Epperly MW et al. Intratracheal injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis. Int J Radiat Oncol Phys 1999; 43: 169-181.
    • (1999) Int J Radiat Oncol Phys , vol.43 , pp. 169-181
    • Epperly, M.W.1
  • 3
    • 0032605109 scopus 로고    scopus 로고
    • MnSOD-plasmid/liposome pulmonary radioprotective gene therapy: Modulation of irradiation-induced mRNA for IL-1, TNF-α, and TGF-β correlates with delay of organizing alveolitis/fibrosis
    • Epperly MW, Travis EL, Sikora C, Greenberger JS. MnSOD-plasmid/liposome pulmonary radioprotective gene therapy: modulation of irradiation-induced mRNA for IL-1, TNF-α, and TGF-β correlates with delay of organizing alveolitis/fibrosis. Biol Blood Marrow Transplant 1999; 5: 204-214.
    • (1999) Biol Blood Marrow Transplant , vol.5 , pp. 204-214
    • Epperly, M.W.1    Travis, E.L.2    Sikora, C.3    Greenberger, J.S.4
  • 4
    • 0029889817 scopus 로고    scopus 로고
    • Stromal cell involvement in leukemogenesis and carcinogenesis
    • Greenberger JS et al. Stromal cell involvement in leukemogenesis and carcinogenesis. In Vivo 1996; 10: 1-18.
    • (1996) In Vivo , vol.10 , pp. 1-18
    • Greenberger, J.S.1
  • 5
    • 0032888334 scopus 로고    scopus 로고
    • Prevention of irradiation-induced esophagitis by intraesophageal plasmid/liposome delivery of the human MnSOD transgene
    • Stickle RL et al. Prevention of irradiation-induced esophagitis by intraesophageal plasmid/liposome delivery of the human MnSOD transgene. Radiat Oncol Invest 1999; 7: 204-217.
    • (1999) Radiat Oncol Invest , vol.7 , pp. 204-217
    • Stickle, R.L.1
  • 6
    • 0343632014 scopus 로고    scopus 로고
    • Plasmid/liposome transfer of the human MnSOD transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture
    • in press
    • Epperly MW et al. Plasmid/liposome transfer of the human MnSOD transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture. Radiat Oncol Invest 1999 (in press).
    • (1999) Radiat Oncol Invest
    • Epperly, M.W.1
  • 7
    • 0027483695 scopus 로고
    • The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman SM et al. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-5283.
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
    • Freeman, S.M.1
  • 8
    • 0029996360 scopus 로고    scopus 로고
    • Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins
    • Mesnil M et al. Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc Natl Acad Sci USA 1996; 93: 1831-1835.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1831-1835
    • Mesnil, M.1
  • 9
    • 0033027240 scopus 로고    scopus 로고
    • Evidence for pronounced bystander effects caused by nonuniform distributions of radio-activity using a novel three-dimensional tissue culture model
    • Bishayee A, Ran DV, Howell RW. Evidence for pronounced bystander effects caused by nonuniform distributions of radio-activity using a novel three-dimensional tissue culture model. Radiat Res 1999; 152: 88-97.
    • (1999) Radiat Res , vol.152 , pp. 88-97
    • Bishayee, A.1    Ran, D.V.2    Howell, R.W.3
  • 10
    • 0033556690 scopus 로고    scopus 로고
    • The combined effect of interferon beta and radiation on five human tumor cell lines and embryonal lung fibroblasts
    • Schmidberger H et al. The combined effect of interferon beta and radiation on five human tumor cell lines and embryonal lung fibroblasts. Int J Radiat Oncol Biol Phys 1999; 43: 405-412.
    • (1999) Int J Radiat Oncol Biol Phys , vol.43 , pp. 405-412
    • Schmidberger, H.1
  • 11
    • 0032526178 scopus 로고    scopus 로고
    • Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine
    • Lawrence TS et al. Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine. Cancer Res 1998; 58: 2588-2593.
    • (1998) Cancer Res , vol.58 , pp. 2588-2593
    • Lawrence, T.S.1
  • 12
    • 0032529454 scopus 로고    scopus 로고
    • Suicide gene therapy of chemically induced mammary tumor in rat: Efficacy and distant bystander effect
    • Wei MX et al. Suicide gene therapy of chemically induced mammary tumor in rat: efficacy and distant bystander effect. Cancer Res 1998; 58: 3529-3532.
    • (1998) Cancer Res , vol.58 , pp. 3529-3532
    • Wei, M.X.1
  • 13
    • 0032505770 scopus 로고    scopus 로고
    • Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient Connexin43 gap junction formation
    • McMasters RA et al. Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient Connexin43 gap junction formation. Hum Gene Ther 1998; 9: 2253-2261.
    • (1998) Hum Gene Ther , vol.9 , pp. 2253-2261
    • McMasters, R.A.1
  • 14
    • 0032440742 scopus 로고    scopus 로고
    • The bystander effect in the HSV-tk/ganciclovir system and its relationship to gap junctional communication
    • Touraine RL, Ishii-Morita H, Ramsey WJ, Blaese RM. The bystander effect in the HSV-tk/ganciclovir system and its relationship to gap junctional communication. Gene Therapy 1998; 5: 1705-1711.
    • (1998) Gene Therapy , vol.5 , pp. 1705-1711
    • Touraine, R.L.1    Ishii-Morita, H.2    Ramsey, W.J.3    Blaese, R.M.4
  • 15
    • 0032502845 scopus 로고    scopus 로고
    • Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase
    • Boucher PD, Ruch RJ, Shewach DS. Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase. Hum Gene Ther 1998; 9: 801-814.
    • (1998) Hum Gene Ther , vol.9 , pp. 801-814
    • Boucher, P.D.1    Ruch, R.J.2    Shewach, D.S.3
  • 16
    • 0032549688 scopus 로고    scopus 로고
    • Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase ganciclovir-based gene therapy of human gastrointestinal tumor cells
    • Yang L et al. Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase ganciclovir-based gene therapy of human gastrointestinal tumor cells. Hum Gene Ther 1998; 9: 719-728.
    • (1998) Hum Gene Ther , vol.9 , pp. 719-728
    • Yang, L.1
  • 17
    • 0031976061 scopus 로고    scopus 로고
    • Bystander effect-mediated therapy of experimental brain tumor by genetically engineered tumor cells
    • Namba H et al. Bystander effect-mediated therapy of experimental brain tumor by genetically engineered tumor cells. Hum Gene Ther 1998; 9: 5-11.
    • (1998) Hum Gene Ther , vol.9 , pp. 5-11
    • Namba, H.1
  • 18
    • 0028141973 scopus 로고
    • Radiation induction of immediate-early genes: Effectors of the radiation-stress response
    • Weichselbaum RR, Hallahan D, Fuks Z, Kufe D. Radiation induction of immediate-early genes: effectors of the radiation-stress response, Int J Radiat Oncol Biol Phys 1994; 30: 229-234.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 229-234
    • Weichselbaum, R.R.1    Hallahan, D.2    Fuks, Z.3    Kufe, D.4
  • 19
    • 0026078126 scopus 로고
    • Protein kinase C mediates X-ray inducibility of nuclear signal transducers EGR1 and JUN
    • Hallahan DE et al. Protein kinase C mediates X-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc Natl Acad Sci USA 1991; 88: 2156-2160.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2156-2160
    • Hallahan, D.E.1
  • 20
    • 0028242871 scopus 로고
    • Membrane-derived second messenger regulates X-ray-mediated TNF-α gene induction
    • Hallahan DE et al. Membrane-derived second messenger regulates X-ray-mediated TNF-α gene induction. Proc Natl Acad Sci USA 1994; 91: 4897-4901.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4897-4901
    • Hallahan, D.E.1
  • 21
    • 0031832193 scopus 로고    scopus 로고
    • Induction of serum amyloid A inflammatory response genes in irradiated bone marrow cells
    • Goltry KL, Epperly MW, Greenberger JS. Induction of serum amyloid A inflammatory response genes in irradiated bone marrow cells. Radiat Res 1998; 149: 570-578.
    • (1998) Radiat Res , vol.149 , pp. 570-578
    • Goltry, K.L.1    Epperly, M.W.2    Greenberger, J.S.3
  • 22
    • 0033564974 scopus 로고    scopus 로고
    • Blockade of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing irradiation
    • Gorski DH et al. Blockade of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing irradiation. Cancer Res 1999; 59: 3374-3378.
    • (1999) Cancer Res , vol.59 , pp. 3374-3378
    • Gorski, D.H.1
  • 23
    • 0032125963 scopus 로고    scopus 로고
    • Gene therapy for oxidant injury-related diseases: Adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury
    • Danel C et al. Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury. Hum Gene Ther 1998; 9: 1487-1496.
    • (1998) Hum Gene Ther , vol.9 , pp. 1487-1496
    • Danel, C.1
  • 24
    • 0032503658 scopus 로고    scopus 로고
    • Redox gene therapy protects human IB-3 lung epithelial cells against ionizing radiation-induced apoptosis
    • Zwacka RM et al. Redox gene therapy protects human IB-3 lung epithelial cells against ionizing radiation-induced apoptosis. Hum Gene Ther 1998; 9: 1381-1386.
    • (1998) Hum Gene Ther , vol.9 , pp. 1381-1386
    • Zwacka, R.M.1
  • 25
    • 0031976062 scopus 로고    scopus 로고
    • Aerosolization of cationic lipid:pDNA complexes - In vitro optimization of nebulizer parameters for human clinical studies
    • Eastman SJ et al. Aerosolization of cationic lipid:pDNA complexes - in vitro optimization of nebulizer parameters for human clinical studies. Hum Gene Ther 1998; 9: 43-52.
    • (1998) Hum Gene Ther , vol.9 , pp. 43-52
    • Eastman, S.J.1
  • 26
    • 0342326989 scopus 로고    scopus 로고
    • Considerations in optimizing radiation therapy for non-small cell lung cancer
    • International Symposium on Thoracic Malignancies
    • Greenberger JS et al. Considerations in optimizing radiation therapy for non-small cell lung cancer. (International Symposium on Thoracic Malignancies). Chest 1998; 113: 465-525.
    • (1998) Chest , vol.113 , pp. 465-525
    • Greenberger, J.S.1
  • 27
    • 0342761691 scopus 로고    scopus 로고
    • Results of multifield conformal radiation therapy of non-small cell lung cancer using multileaf collimation beams
    • Bahri S et al. Results of multifield conformal radiation therapy of non-small cell lung cancer using multileaf collimation beams. Radiat Oncol Invest 1999; 7: 204-217.
    • (1999) Radiat Oncol Invest , vol.7 , pp. 204-217
    • Bahri, S.1
  • 28
    • 0026725333 scopus 로고
    • Interstitial pneumonitis after hyperfractionated TBI in HLA-matched T-depleted bone marrow transplantation
    • Latini P et al. Interstitial pneumonitis after hyperfractionated TBI in HLA-matched T-depleted bone marrow transplantation. Int J Radiat Oncol Biol Phys 1992; 23: 401-405.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 401-405
    • Latini, P.1
  • 29
    • 0023130742 scopus 로고
    • Acute radiation-induced pulmonary damage: A clinical study on the response to fractionated radiation therapy
    • Mah K, Van Dyk F, Keane T, Poon P. Acute radiation-induced pulmonary damage: a clinical study on the response to fractionated radiation therapy. Int J Radiat Oncol Biol Phys 1987; 13: 179-188.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 179-188
    • Mah, K.1    Van Dyk, F.2    Keane, T.3    Poon, P.4
  • 30
    • 0013624406 scopus 로고
    • Resistance of hematopoietic stem cells to X-irradiation at clinical low-dose-rate is induced by several classes of oncogenes
    • FitzGerald TJ et al. Resistance of hematopoietic stem cells to X-irradiation at clinical low-dose-rate is induced by several classes of oncogenes. Radiat Res 1990; 122: 44-53.
    • (1990) Radiat Res , vol.122 , pp. 44-53
    • FitzGerald, T.J.1
  • 31
    • 0028986423 scopus 로고
    • Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine
    • Olive PL. Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine. Br J Cancer 1995; 71: 529-536.
    • (1995) Br J Cancer , vol.71 , pp. 529-536
    • Olive, P.L.1
  • 32
    • 0033398125 scopus 로고    scopus 로고
    • Overexpression of the human MnSOD transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest
    • Epperly MW et al. Overexpression of the human MnSOD transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest. Radiat Oncol Invest 1999; 7: 331-342.
    • (1999) Radiat Oncol Invest , vol.7 , pp. 331-342
    • Epperly, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.