Amelioration of radiation-induced fibrosis. Inhibition of transforming growth factor-β signaling by halofuginone

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15167-15176

  Xavier, Sandhya ^a   Piek, Ester ^a   Fujii, Makiko ^a   Javelaud, Delphine ^b   Mauviel, Alaìn ^b   Flanders, Kathy C ^a   Samuni, Ayelet M ^a   Felici, Angelina ^a   Raiss, Michael ^c   Yarkoni, Shai ^d   Sowers, Anastasia ^a   Mitchell, James B ^a   Roberts, Anita B ^a   Russo, Angelo ^a,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAINT LOUIS HOSPITAL   (France)

^c ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d Collgard Biopharmaceuticals Ltd ^*  (Israel)

^e Bldg 10 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; IONIZING RADIATION; RADIATION CHEMISTRY; SIGNALING; TISSUE;

AMELIORATION; FIBROSIS; RADIATION INJURY;

BIOCHEMISTRY;

HALOFUGINONE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST EPITHELIUM; CANCER RADIOTHERAPY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FIBROSIS; HUMAN; HUMAN CELL; IONIZING RADIATION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION ATTENUATION; RADIATION EXPOSURE; RADIATION INJURY; SQUAMOUS CELL CARCINOMA; TISSUE REPAIR; TUMOR GROWTH; WOUND HEALING;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; COS CELLS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FIBROSIS; GENE DELETION; GENES, REPORTER; HUMANS; IMMUNOBLOTTING; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C3H; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PIPERIDINES; PLASMIDS; PROTEIN SYNTHESIS INHIBITORS; QUINAZOLINES; QUINAZOLINONES; RADIATION PNEUMONITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TIME FACTORS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA;

EID: 2442481893     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309798200     Document Type: Article

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