Effects of dietary antioxidant supplementation on the development of malignant lymphoma and other neoplastic lesions in mice exposed to proton or iron-ion radiation

Radiation Research

Volumn 169, Issue 6, 2008, Pages 615-625

  Kennedy, Ann R ^a,c   Davis, James G ^a   Carlton, William ^b   Ware, Jeffrey H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PURDUE UNIVERSITY   (United States)

^c 195 John Morgan Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL SUCCINATE; ASCORBIC ACID; BOWMAN BIRK INHIBITOR; SELENOMETHIONINE; THIOCTIC ACID; UBIDECARENONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; COSMIC RADIATION; DIET SUPPLEMENTATION; HISTOPATHOLOGY; ION THERAPY; LYMPHOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE; RADIATION EXPOSURE; SURVIVAL;

ANIMALS; ANTIOXIDANTS; DIET; DIETARY SUPPLEMENTS; HEMATOPOIETIC STEM CELLS; IONS; IRON; LYMPHOMA; MALE; MICE; MICE, INBRED CBA; NEOPLASMS, RADIATION-INDUCED; PILOT PROJECTS; PROTONS; TIME FACTORS;

ANIMALIA; GLYCINE MAX; MUS;

EID: 44849121345     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1296.1     Document Type: Article

References (48)

1. X. S. Wan, P. Bloch, J. H. Ware, Z. Zhou, J. J. Donahue, J. Guan, J. Stewart and A. R. Kennedy, Detection of oxidative stress induced by low- and high-linear energy transfer radiation in cultured human epithelial cells. Radiat. Res. 163, 364-368 (2005).
2. X. S. Wan, J. H. Ware, Z. Zhou, J. J. Donahue and A. R. Kennedy, Protection against radiation induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents. Int. J. Radiat. Oncol. Biol. Phys. 64, 1475-1481 (2006).
3. A. R. Kennedy, J. H. Ware, J. Guan, J. J. Donahue, J. E. Biaglow, Z. Zhou, J. Stewart, M. Vasquez and X. S. Wan, Selenomethionine protects against adverse biological effects induced by space radiation. Free Radic. Biol. Med. 36, 259-266 (2004).
4. J. Guan, X. S. Wan, Z. Zhou, J. H. Ware, J. J. Donahue, J. E. Biaglow and A. R. Kennedy, The effects of dietary supplement agents on space radiation-induced oxidative stress in Sprague-Dawley rats. Radiat. Res. 162, 572-579 (2004).
5. J. Guan, J. Stewart, J. H. Ware, Z. Zhou, J. J. Donahue and A. R. Kennedy, Effects of dietary supplements on the space radiation-induced reduction in total antioxidant status in CBA mice. Radiat. Res. 165, 373-378 (2006).
6. A. R. Kennedy, J. Guan and J. H. Ware, Countermeasures against space radiation induced oxidative stress in mice. Radiat. Environ. Biophys. 46, 161-165 (2007).
7. H. Sies, Oxidative Stress. Academic Press, New York, 1985.
8. National Research Council, Committee on the Biological Effects of Ionizing Radiation, Health Effects of Exposure to Low Levels of Ionizing Radiation (BEIR V). National Academy Press, Washington, DC, 1990.
9. P. M. Newberne and A. E. Rogers, The role of nutrients in cancer causation. Princess Takamatsu Symp. 16, 205-222 (1985).
10. R. L. Nelson, Dietary minerals and colon carcinogenesis. Anticancer Res. 7, 259-269 (1987).
11. J. Y. Li, P. R. Taylor, B. Li, S. Dawsey, G. Q. Wang, A. G. Ershow, W. Guo, S. F. Liu, C. S. Yang and W. J. Blot, Nutrition intervention trials in Linxian, China: multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia. J. Natl. Cancer Inst. 85, 1492-1498 (1993).
12. W. J. Blot, J. Y. Li, P. R. Taylor, W. Guo, S. Dawsey, G. Q. Wang, C. S. Yang, S. F. Zheng, M. Gail and B. Li, Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J. Natl. Cancer Inst. 85, 1483-1492 (1993).
13. S. M. Smith, J. E. Davis-Street, B. L. Rice, J. L. Nillen, P. L. Gillman and G. Block, Nutritional status assessment in semiclosed environments: ground-based and space flight studies in humans. J. Nutr. 131, 2053-2061 (2001).
14. F. J. Burns, M-S. Tang, K. Frenkel, A. Nadas, F. Wu, A. Uddin and R. Zhang, Induction and prevention of carcinogenesis in rat skin exposed to space radiation. Radiat. Environ. Biophys. 46, 195-199 (2007).
15. A. R. Kennedy, Z. Zhou, J. J. Donahue and J. H. Ware, Protection against space radiation-induced adverse biological effects by the Bowman-Birk inhibitor and antioxidants. Radiat. Res. 166, 327-332 (2006).
16. A. R. Kennedy, Anticarcinogenic activity of protease inhibitors: Overview. In Protease Inhibitors as Cancer Chemopreventive Agents (W. Troll and A. R. Kennedy, Eds.), pp. 9-64. Plenum Press, New York, 1993.
17. A. R. Kennedy, Chemopreventive agents: protease inhibitors. Pharmacol. Ther. 78, 167-209 (1998).
18. A. R. Kennedy, The status of human trials utilizing Bowman-Birk inhibitor concentrate from soybeans. In Soy in Health and Disease Prevention (M. Sugano, Ed.), pp. 207-223. CRC Press, Boca Raton, FL, 2005.
19. J. G. Page, J. E. Heath, R. D. May and J. F. Martin, 13-week toxicity study of Bowman-Birk Inhibitor Concentrate (BBIC) in rats. Final Report to the National Cancer Institute, Southern Research Institute, Birmingham, AL, 1994.
20. D. G. Serota, Six-month oral toxicity study of Bowman-Birk Inhibitor Concentrate (BBIC) in Mice. Final Report to the National Cancer Institute, Division of Cancer Prevention, Chemoprevention Branch, MPI Research, Inc., Mattawan, MI, 2000.
21. +/- (p53 knockout) mice. Int. J. Toxicol. 25, 219-228 (2006).
22. A. N. Friedman, A. G. Bostom, P. Laliberty, J. Selhub and D. Shemin, The effect of N-acetylcysteine on plasma total homocysteine levels in hemodialysis: a randomized, controlled study. Am. J. Kidney Dis. 41, 442-446 (2003).
23. J. L. Evans, C. J. Heymann, I. D. Goldfine and L. A. Gavin, Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid. Endocr. Pract. 8, 29-35 (2002).
24. S. C. Kogan, J. M. Ward, M. R. Anver, J. J. Berman, C. Brayton, R. D. Cardiff, J. S. Carter, S. de Coronado, J. R. Downing and H. C. Morse, III, Hematopathology subcommittee of the Mouse Models of Human Cancers Consortium. Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood 100, 238-245 (2002).
25. I. R. Major, Induction of myeloid leukaemia by whole-body single exposure of CBA male mice to x-rays. Br. J. Cancer 40, 903-913 (1979).
26. E. L. Alpen, P. Powers-Risius, S. B. Curtis and R. DeGuzman, Tumorigenic potential of high-Z, high-LET charged particle radiations. Radiat. Res. 136, 382-391 (1993).
27. E. L. Alpen, P. Powers-Risius, S. B. Curtis, R. DeGuzman and R. J. M. Fry, Fluence-based relative biological effectiveness for charged particle carcinogenesis in mouse Harderian gland. Adv. Space Res. 14, 573-581 (1994).
28. R. J. M. Fry, P. Powers-Risius, E. L. Alpen and E. J. Ainsworth, High-LET radiation carcinogenesis. Radiat. Res. Suppl. 8, S188-S195 (1985).
29. T. Tillmann, K. Kamino and U. Mohr, Incidence and spectrum of spontaneous neoplasms in male and female CBA/J mice. Exp. Toxicol. Pathol. 52, 221-225 (2000).
30. A. R. Kennedy, Y. Beazer-Barclay, K. W. Kinzler and P. M. Newberne, Suppression of carcinogenesis in the intestines of Min mice by the soybean-derived Bowman-Birk inhibitor. Cancer Res. 56, 679-682 (1996).
31. E. Boulton, H. Cleary, D. Papworth and M. Plumb, Susceptibility to radiation-induced leukaemia/lymphoma is genetically separable from sensitivity to radiation-induced genomic instability. Int. J. Radiat. Biol. 77, 21-29 (2001).
32. K. Yoshida, T. Inoue, Y. Hirabayashi, T. Matsumura, K. Nemoto and T. Sado, Radiation-induced myeloid leukemia in mice under calorie restriction. Leukemia 11 (Suppl.), 410-412 (1997).
33. K. Yoshida, T. Inoue, K. Nojima, Y. Hirabayashi and T. Sado, Calorie restriction reduces the incidence of myeloid leukemia induced by a single whole-body radiation in C3H/He mice. Proc. Natl. Acad. Sci. USA 94, 2615-2619 (1997).
34. H. S. Kaplan and M. B. Brown, Testosterone prevention of postirradiation lymphomas in C57 black mice. Cancer Res. 12, 445-447 (1952).
35. P. Wasi and M. Block, The histopathologic study of the development of the irradiation-induced leukemia in C57BL mice and its inhibition by testosterone. Cancer Res. 21, 463-473 (1961).
36. A. C. Upton, U. K. Jenkins and J. W. Conklin, Myeloid leukemia in the mouse. Ann. NY Acad. Sci. 114, 189-201 (1964).
37. R. K. Boutwell, Model systems for defining initiation, promotion, and progression of skin neoplasms. Prog. Clin. Biol. Res. 298, 3-15 (1989).
38. R. Suss, V. Kinzel and J. D. Scribner, Cancer Experiments and Concepts, pp. 57-58. Springer-Verlag, New York, 1973
39. J. F. Dicello, A. Christian, F. A. Cucinotta, D. S. Gridley, R. Kathirithamby, J. Mann, A. R. Markham, M. F. Moyers, G. R. Novak and D. Huso, In vivo mammary tumourigenesis in the Sprague-Dawley rat and microdosimetric correlates. Phys. Med. Biol. 49, 3817-3830 (2004).
40. F. A. Cucinotta, W. Schimmerling, J. W. Wilson, L. E. Peterson, G. D. Badhwar, P. B. Saganti and J. F. Dicello, Space radiation cancer risks and uncertainties for Mars missions. Radiat. Res. 156, 682-688 (2001).
41. M. Urano, L. J. Verhey, M. Goitein, J. E. Tepper, H. D. Suit, O. Mendiondo, E. S. Gragoudas and A. Koehler, Relative biological effectiveness of modulated proton beams in various murine tissues. Int. J. Radiat. Oncol. Biol. Phys. 10, 509-514 (1984).
42. L. Juling-Pohlit, W. Pohlit and H. Blattmann, Repair inhibition in tumours irradiated with fast protons and negative pions. Strahlenther. Onkol. 166, 6-9 (1990).
43. H. S. Kaplan, On the natural history of murine leukemias: presidential address. Cancer Res. 27, 1325-1340 (1967).
44. M. Lieberman and H. H. Kaplan, Leukemogenic activity from radiation-induced lymphoid tumors of mice. Science 130, 387-388 (1959).
45. J. F. Duplan, B. Guillemain and T. Astier, Role of viruses. In Radiation Carcinogenesis (A. C. Upton, R. E. Albert, F. J. Burns and R. E. Shore, Eds.), pp. 73-84. Elsevier, New York, 1986
46. I. Berenblum, M. Burger and A. Knyszynski, Inhibition of radiation-induced lymphatic leukemia in C57BL mice by 19S alpha-2-globulin (alpha 2-MG) from human blood serum. Radiat. Res. 60, 501-505 (1974).
47. J. H. Ware, X. S. Wan and A. R. Kennedy, Bowman-Birk inhibitor suppresses production of superoxide anion radicals in differentiated HL-60 cells. Nutr. Cancer 33, 174-177 (1999).
48. S. Arbogast, J. Smith, Y. Matuszczak, B. Hardin, J. Moylan, J. D. Smith, J. Ware, A. R. Kennedy and M. B. Reid, Bowman-Birk Inhibitor Concentrate prevents atrophy, weakness and oxidative stress in soleus muscle of limdlimb-unloaded mice. J. Appl. Physiol. 102, 956-964 (2007).