Pleiotropic effects of statins - Basic research and clinical perspectives

Circulation Journal

Volumn 74, Issue 5, 2010, Pages 818-826

  Zhou, Qian ^a   Liao, James K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cholesterol; Pleiotropic effects; Rho kinase; Statin; Vascular

Indexed keywords

ATORVASTATIN; CHOLESTEROL; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEIN CDC42; RAC PROTEIN; RHO FACTOR; RHO KINASE; ROSUVASTATIN; SIMVASTATIN;

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CORONARY ARTERY ATHEROSCLEROSIS; DISEASE MODEL; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; ENDOTHELIUM; ENZYME INHIBITION; HEART VENTRICLE REMODELING; HUMAN; HYPERCHOLESTEROLEMIA; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIMARY PREVENTION; RECOMMENDED DRUG DOSE; REVIEW; SECONDARY PREVENTION; STROKE; THROMBOCYTE; VASCULAR SMOOTH MUSCLE; VASCULITIS;

CARDIOVASCULAR DISEASES; CDC42 GTP-BINDING PROTEIN; CHOLESTEROL; ENDOTHELIUM, VASCULAR; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TERPENES;

EID: 77951709095     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-10-0110     Document Type: Review

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