메뉴 건너뛰기




Volumn 100, Issue 2, 1999, Pages 178-184

Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts

Author keywords

Ischemia; Leukocytes; Myocardium; Reperfusion; Simvastatin

Indexed keywords

CD18 ANTIGEN; NITRIC OXIDE; PADGEM PROTEIN; PRAVASTATIN; SIMVASTATIN;

EID: 0033551539     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.100.2.178     Document Type: Article
Times cited : (324)

References (39)
  • 1
    • 0001409863 scopus 로고
    • Endothelial and myocardial injury during ischemia and reperfusion: Pathogenesis and therapeutic implications
    • Forman MB, Kolodgie FD, Jenkins M, Virmani R. Endothelial and myocardial injury during ischemia and reperfusion: pathogenesis and therapeutic implications. J Am Coll Cardiol. 1993;21:1245-1253.
    • (1993) J Am Coll Cardiol , vol.21 , pp. 1245-1253
    • Forman, M.B.1    Kolodgie, F.D.2    Jenkins, M.3    Virmani, R.4
  • 2
    • 0025542037 scopus 로고
    • Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
    • Tsao PS, Aoki N, Lefer DJ, Johnson G III. Lefer AM. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation. 1990;82:1402-1412.
    • (1990) Circulation , vol.82 , pp. 1402-1412
    • Tsao, P.S.1    Aoki, N.2    Lefer, D.J.3    Johnson G. III4    Lefer, A.M.5
  • 4
    • 0020579761 scopus 로고
    • Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog
    • Engler RL, Schmid-Schönbein GW, Pavlec RS. Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog. Am J Pathol. 1983;111:98-111.
    • (1983) Am J Pathol , vol.111 , pp. 98-111
    • Engler, R.L.1    Schmid-Schönbein, G.W.2    Pavlec, R.S.3
  • 5
    • 0025819503 scopus 로고
    • Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia
    • Lefer AM, Tsao PS, Lefer DJ, Ma X-L. Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia. FASEB J. 1991;5:2029-2034.
    • (1991) FASEB J , vol.5 , pp. 2029-2034
    • Lefer, A.M.1    Tsao, P.S.2    Lefer, D.J.3    Ma, X.-L.4
  • 6
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss SJ. Tissue destruction by neutrophils. N Engl J Med. 1989;320: 365-376.
    • (1989) N Engl J Med , vol.320 , pp. 365-376
    • Weiss, S.J.1
  • 7
    • 0028003456 scopus 로고
    • Isolated cardiac myocytes are sensitized by hypoxia-reoxygenation to neutrophil released mediators
    • Buerke M, Weyrich AS, Lefer AM. Isolated cardiac myocytes are sensitized by hypoxia-reoxygenation to neutrophil released mediators. Am J Physiol. 1994;266:H128-H136.
    • (1994) Am J Physiol , vol.266
    • Buerke, M.1    Weyrich, A.S.2    Lefer, A.M.3
  • 8
    • 0026785318 scopus 로고
    • Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion
    • Ma X-L, Lefer DJ, Lefer AM, Rothlein R. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion. Circulation. 1992;86:937-946.
    • (1992) Circulation , vol.86 , pp. 937-946
    • Ma, X.-L.1    Lefer, D.J.2    Lefer, A.M.3    Rothlein, R.4
  • 10
    • 0027164220 scopus 로고
    • In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury
    • Weyrich AS, Ma X-L, Lefer DJ, Albertine KH, Lefer AM. In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J Clin Invest. 1993;91: 2620-2629.
    • (1993) J Clin Invest , vol.91 , pp. 2620-2629
    • Weyrich, A.S.1    Ma, X.-L.2    Lefer, D.J.3    Albertine, K.H.4    Lefer, A.M.5
  • 11
    • 85047680729 scopus 로고
    • Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury
    • Lefer AM, Weyrich AS, Buerke M. Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury. Curdiovasc Res. 1994;28:289-294.
    • (1994) Curdiovasc Res , vol.28 , pp. 289-294
    • Lefer, A.M.1    Weyrich, A.S.2    Buerke, M.3
  • 12
    • 0030499777 scopus 로고    scopus 로고
    • Biological mechanisms for the clinical success of lipid-lowering in coronary artery disease and the use of surrogate end-points
    • Kinlay S, Selwyn AP, Delagrange D, Creager MA, Libby P, Ganz P. Biological mechanisms for the clinical success of lipid-lowering in coronary artery disease and the use of surrogate end-points. Curr Opin Lipidol. 1996;7:389-397.
    • (1996) Curr Opin Lipidol , vol.7 , pp. 389-397
    • Kinlay, S.1    Selwyn, A.P.2    Delagrange, D.3    Creager, M.A.4    Libby, P.5    Ganz, P.6
  • 13
    • 0029650740 scopus 로고
    • Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms
    • Levine GN, Keaney JF Jr, Vita JA. Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms. N Engl J Med. 1995;332:512-521.
    • (1995) N Engl J Med , vol.332 , pp. 512-521
    • Levine, G.N.1    Keaney J.F., Jr.2    Vita, J.A.3
  • 15
    • 0030663693 scopus 로고    scopus 로고
    • Vascular effects of statins in stroke
    • Delanty N, Vaughan CJ. Vascular effects of statins in stroke. Stroke. 1997;28:2315-2320.
    • (1997) Stroke , vol.28 , pp. 2315-2320
    • Delanty, N.1    Vaughan, C.J.2
  • 16
    • 0023754423 scopus 로고
    • Discovery, biochemistry and biology of lovastatin
    • Alberts AW. Discovery, biochemistry and biology of lovastatin. Am J Cardiol. 1988;62:10J-15J.
    • (1988) Am J Cardiol , vol.62
    • Alberts, A.W.1
  • 17
    • 0000306390 scopus 로고    scopus 로고
    • Statins do more than just lower cholesterol
    • Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet. 1996;348:1079-1082.
    • (1996) Lancet , vol.348 , pp. 1079-1082
    • Vaughan, C.J.1    Murphy, M.B.2    Buckley, B.M.3
  • 18
    • 0030025202 scopus 로고    scopus 로고
    • Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion
    • Pabla R, Buda AJ, Flynn DM, Blesse SA, Shin AM, Curtis MJ, Lefer DJ. Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion. Circ Res. 1996;78:65-72.
    • (1996) Circ Res , vol.78 , pp. 65-72
    • Pabla, R.1    Buda, A.J.2    Flynn, D.M.3    Blesse, S.A.4    Shin, A.M.5    Curtis, M.J.6    Lefer, D.J.7
  • 19
  • 20
    • 0023614493 scopus 로고
    • Harvesting the circulating pool of polymorphonuclear leukocytes by hetastarch exchange transfusion (HET): Yield and function assessment
    • Williams JH Jr, Moser KM, Ulich T, Cairo MS. Harvesting the circulating pool of polymorphonuclear leukocytes by hetastarch exchange transfusion (HET): yield and function assessment. J Leuko Biol. 1987; 42:455-462.
    • (1987) J Leuko Biol , vol.42 , pp. 455-462
    • Williams J.H., Jr.1    Moser, K.M.2    Ulich, T.3    Cairo, M.S.4
  • 21
    • 0027303824 scopus 로고
    • Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium
    • Ma X-L, Weyrich AS, Lefer DJ, Buerke M, Albertine KH, Kishimoto TK, Lefer AM. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation. 1993;88:649-658.
    • (1993) Circulation , vol.88 , pp. 649-658
    • Ma, X.-L.1    Weyrich, A.S.2    Lefer, D.J.3    Buerke, M.4    Albertine, K.H.5    Kishimoto, T.K.6    Lefer, A.M.7
  • 22
    • 0032578534 scopus 로고    scopus 로고
    • Synergism between platelets and neutrophils in provoking cardiac dysfunction after ischemia and reperfusion: Role of selectins
    • Lefer AM, Campbell B, Scalia R, Lefer DJ. Synergism between platelets and neutrophils in provoking cardiac dysfunction after ischemia and reperfusion: role of selectins. Circulation. 1998;98:1322-1328.
    • (1998) Circulation , vol.98 , pp. 1322-1328
    • Lefer, A.M.1    Campbell, B.2    Scalia, R.3    Lefer, D.J.4
  • 23
    • 0029745661 scopus 로고    scopus 로고
    • Direct measurement of nitric oxide release from vascular endothelial cells
    • Guo JP, Murohara T, Buerke M, Scalia R, Lefer AM. Direct measurement of nitric oxide release from vascular endothelial cells. J Appl Physiol. 1996;81:774-779.
    • (1996) J Appl Physiol , vol.81 , pp. 774-779
    • Guo, J.P.1    Murohara, T.2    Buerke, M.3    Scalia, R.4    Lefer, A.M.5
  • 24
    • 0024542681 scopus 로고
    • Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits
    • Osborne JA, Siegman MJ, Sedar AW, Mooers SU, Lefer AM. Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits. Am J Physiol. 1989;256:C591-C597.
    • (1989) Am J Physiol , vol.256
    • Osborne, J.A.1    Siegman, M.J.2    Sedar, A.W.3    Mooers, S.U.4    Lefer, A.M.5
  • 25
    • 0022599509 scopus 로고
    • Effect of hypercholesterolemia on vascular reactivity in the rabbit, I: Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits
    • Verbeuren TJ, Jordaens FH, Zoonekeyn LL, Van Hove CE, Coene MC, Herman AG. Effect of hypercholesterolemia on vascular reactivity in the rabbit, I: endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits. Circ Res. 1986;58:552-564.
    • (1986) Circ Res , vol.58 , pp. 552-564
    • Verbeuren, T.J.1    Jordaens, F.H.2    Zoonekeyn, L.L.3    Van Hove, C.E.4    Coene, M.C.5    Herman, A.G.6
  • 26
    • 0025677318 scopus 로고
    • Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta
    • Minor RL Jr, Myers PR, Guerra R Jr, Bates JN, Harrison DG. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. J Clin Invest. 1990;86:2109-2116.
    • (1990) J Clin Invest , vol.86 , pp. 2109-2116
    • Minor R.L., Jr.1    Myers, P.R.2    Guerra R., Jr.3    Bates, J.N.4    Harrison, D.G.5
  • 27
    • 0019426739 scopus 로고
    • Effects of moderate hypercholesterolemia on rabbit endothelium
    • Stemerman MB. Effects of moderate hypercholesterolemia on rabbit endothelium. Arteriosclerosis. 1981;1:25-32.
    • (1981) Arteriosclerosis , vol.1 , pp. 25-32
    • Stemerman, M.B.1
  • 28
    • 0025961786 scopus 로고
    • Endothelial alterations in hypercholesterolaemia and atherosclerosis
    • Lefer AM, Sedar AW. Endothelial alterations in hypercholesterolaemia and atherosclerosis. Pharmacol Res. 1991;23:1-12.
    • (1991) Pharmacol Res , vol.23 , pp. 1-12
    • Lefer, A.M.1    Sedar, A.W.2
  • 29
    • 0023218213 scopus 로고
    • Increased ischemia-reperfusion injury to the heart associated with short-term, diet-induced hypercholesterolemia in rabbits
    • Tilton RG, Cole PA, Zions JD, Daugherty A, Larson KB, Sutera SP, Kilo C, Williamson JR. Increased ischemia-reperfusion injury to the heart associated with short-term, diet-induced hypercholesterolemia in rabbits. Circ Res. 1987;60:551-559.
    • (1987) Circ Res , vol.60 , pp. 551-559
    • Tilton, R.G.1    Cole, P.A.2    Zions, J.D.3    Daugherty, A.4    Larson, K.B.5    Sutera, S.P.6    Kilo, C.7    Williamson, J.R.8
  • 31
    • 0024504128 scopus 로고
    • Cardiovascular effects of acute hypercholesterolemia in rabbits: Reversal with lovastatin treatment
    • Osborne JA, Lento PH, Siegfried MR, Stahl GL, Fusman B, Lefer AM. Cardiovascular effects of acute hypercholesterolemia in rabbits: reversal with lovastatin treatment. J Clin Invest. 1989;83:465-473.
    • (1989) J Clin Invest , vol.83 , pp. 465-473
    • Osborne, J.A.1    Lento, P.H.2    Siegfried, M.R.3    Stahl, G.L.4    Fusman, B.5    Lefer, A.M.6
  • 32
    • 0030838319 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors decrease CD11b expression and CD11b-dependent adhesion of monocytes to endothelium and reduce increased adhesiveness of monocytes isolated from patients with hypercholesterolemia
    • Weber C, Erl W, Weber KSC, Weber PC. HMG-CoA reductase inhibitors decrease CD11b expression and CD11b-dependent adhesion of monocytes to endothelium and reduce increased adhesiveness of monocytes isolated from patients with hypercholesterolemia. J Am Coll Cardiol. 1997;30:1212-1217.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1212-1217
    • Weber, C.1    Erl, W.2    Weber, K.S.C.3    Weber, P.C.4
  • 33
    • 0030814892 scopus 로고    scopus 로고
    • Mevalonate-dependent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin
    • Dunzendorfer S, Rothbucher D, Schratzberger P, Reinisch N, Kahler CM, Wiedermann CJ. Mevalonate-dependent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin. Circ Res. 1997;81:963-969.
    • (1997) Circ Res , vol.81 , pp. 963-969
    • Dunzendorfer, S.1    Rothbucher, D.2    Schratzberger, P.3    Reinisch, N.4    Kahler, C.M.5    Wiedermann, C.J.6
  • 34
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs U, La Fata V, Plutzky J, Liao JK. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation. 1998;97: 1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    Fata L. V2    Plutzky, J.3    Liao, J.K.4
  • 35
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase
    • Laufs U, La Fata V, Liao JK. Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem. 1997;272:31725-31729.
    • (1997) J Biol Chem , vol.272 , pp. 31725-31729
    • Laufs, U.1    La Fata, V.2    Liao, J.K.3
  • 36
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger D. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A. 1991;88: 4651-4655.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.3
  • 37
    • 0028128957 scopus 로고
    • Inhibition of endothelialderived nitric oxide promotes P-selectin expression and actions in the rat microcirculation
    • Davenpeck KL, Gauthier TW, Lefer AM. Inhibition of endothelialderived nitric oxide promotes P-selectin expression and actions in the rat microcirculation. Gastmenterology. 1994;107:1050-1058.
    • (1994) Gastmenterology , vol.107 , pp. 1050-1058
    • Davenpeck, K.L.1    Gauthier, T.W.2    Lefer, A.M.3
  • 39
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M, Laufs U, Huang Z, Nakamura T, Huang P, Moskowitz MA, Liao JK. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Natl Acad Sci U S A. 1998;95:8880-8885.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3    Nakamura, T.4    Huang, P.5    Moskowitz, M.A.6    Liao, J.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.