Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer

Biochemical Pharmacology

Volumn 79, Issue 12, 2010, Pages 1781-1790

  Folini, Marco ^a   Pivetta, Claudia ^b   Zagotto, Giuseppe ^b   De Marco, Cinzia ^a   Palumbo, Manlio ^b   Zaffaroni, Nadia ^a   Sissi, Claudia ^b  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Alternative lengthening of telomeres; Bisantrene; G quadruplex; Telomerase; Telomere

Indexed keywords

ANTHRACENE DERIVATIVE; BISANTRENE; DNA; GUANINE QUADRUPLEX; NUCLEIC ACID; TELOMERASE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL AGING; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; FLUOROMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; ISOMER; PRIORITY JOURNAL; PROTEIN BINDING; TELOMERE;

ANTHRACENES; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; COLONIC NEOPLASMS; G-QUADRUPLEXES; HUMANS; INHIBITORY CONCENTRATION 50; ISOMERISM; MELANOMA; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; OSTEOSARCOMA; STRUCTURE-ACTIVITY RELATIONSHIP; TAQ POLYMERASE; TELOMERASE; TELOMERE;

EID: 77951297746     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.02.018     Document Type: Article

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