Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes

Molecular Pharmacology

Volumn 60, Issue 5, 2001, Pages 981-988

  Gowan, Sharon M ^a   Heald, Robert ^b   Stevens, Malcolm F G ^b   Kelland, Lloyd R ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3,11 DIFLUORO 6,8,13 TRIMETHYL 8H QUINO[4,3,2 KL]ACRIDINIUM METHOSULFATE; ACRIDINE DERIVATIVE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; DNA; RHPS4; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG CYTOTOXICITY; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VULVA CARCINOMA;

EID: 0034760505     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.5.981     Document Type: Article

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