1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase

Journal of Medicinal Chemistry

Volumn 41, Issue 17, 1998, Pages 3253-3260

  Perry, Philip J ^a   Gowan, Sharon M ^a   Reszka, Anthony P ^a   Polucci, Paolo ^a,b   Jenkins, Terence C ^a,c   Kelland, Lloyd R ^a   Neidle, Stephen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF CAMERINO   (Italy)

^c UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMIDOANTHRAQUINONE DERIVATIVE; 2,6 DIAMIDOANTHRAQUINONE DERIVATIVE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA POLYMERASE; DOXORUBICIN; ENZYME INHIBITOR; MITOXANTRONE; TELOMERASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; OVARY CARCINOMA; STRUCTURE ACTIVITY RELATION; TELOMERE; TUMOR CELL LINE;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL SURVIVAL; DOXORUBICIN; ENZYME INHIBITORS; FEMALE; GENE AMPLIFICATION; HUMANS; KINETICS; MITOXANTRONE; MOLECULAR STRUCTURE; OVARIAN NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TAQ POLYMERASE; TELOMERASE; TELOMERE; TUMOR CELLS, CULTURED;

EID: 0032514479     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9801105     Document Type: Article

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