A structural determinant that renders Gαi sensitive to activation by GIV/girdin is required to promote cell migration

Journal of Biological Chemistry

Volumn 285, Issue 17, 2010, Pages 12765-12777

  Garcia Marcos, Mikel ^a   Ghosh, Pradipta ^a,b   Ear, Jason ^a,b   Farquhar, Marilyn G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PARTNERS; BIOLOGICAL EFFECTS; BIOLOGICAL FUNCTIONS; CELL MIGRATION; CULTURED CELL; G PROTEIN; G PROTEIN COUPLED RECEPTORS; GROWTH FACTOR; GTPASE-ACTIVATING PROTEIN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELL; HETEROTRIMERIC G PROTEINS; IN-VITRO; PULLDOWN ASSAYS; RECEPTOR ACTIVATOR; SMALL MOLECULES; STRUCTURAL DETERMINANTS; STRUCTURAL FEATURE; TARGET SITES;

CHEMICAL ACTIVATION; CYTOLOGY; NUCLEOTIDES; POSITIVE IONS;

PROTEINS;

ALANINE; ASPARTIC ACID; G PROTEIN COUPLED RECEPTOR; GIRDIN; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HISTIDINE; LEUCINE; PHENYLALANINE; PROTEIN KINASE B; SERINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL STRAIN COS7; CHIMERA; CONTROLLED STUDY; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; CARRIER PROTEINS; CELL MOVEMENT; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HELA CELLS; HUMANS; MICE; MICROFILAMENT PROTEINS; MUTATION, MISSENSE; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; RGS PROTEINS; VESICULAR TRANSPORT PROTEINS;

GREAT ISLAND VIRUS;

EID: 77951248135     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.045161     Document Type: Article

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