Structure of Gαi1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange

Structure

Volumn 13, Issue 7, 2005, Pages 1069-1080

  Johnston, Christopher A ^a   Willard, Francis S ^a,b   Jezyk, Mark R ^a   Fredericks, Zoey ^c,e   Bodor, Erik T ^a   Jones, Miller B ^a,b   Blaesius, Rainer ^c,f   Watts, Val J ^d   Harden, T Kendall ^a   Sondek, John ^a,b   Ramer, J Kevin ^c,g   Siderovski, David P ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Karo Bio USA   (United States)

^d PURDUE UNIVERSITY   (United States)

^e AMGEN INC   (United States)

^f Becton Dickinson Technologies   (United States)

^g Hemocellular Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE; GUANOSINE DIPHOSPHATE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE; BUFFER; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MAGNESIUM; NUCLEOTIDE; PEPTIDE LIBRARY;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; NONHUMAN; NUCLEOTIDE TRANSPORT; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; ELECTRON; ENZYME ACTIVE SITE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC PROCEDURES; KINETICS; MOLECULAR GENETICS; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STEREOISOMERISM; SURFACE PLASMON RESONANCE; TIME; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BIOSENSING TECHNIQUES; BUFFERS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ELECTRONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANINE NUCLEOTIDES; KINETICS; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STEREOISOMERISM; SURFACE PLASMON RESONANCE; TIME FACTORS;

EID: 21744435268     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2005.04.007     Document Type: Article

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