Comparative analysis of the efficacy of A1 adenosine receptor activation of G(i/o)α G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-G(i/o)α fusion proteins

Biochemistry

Volumn 38, Issue 8, 1999, Pages 2272-2278

  Wise, Alan ^a   Sheehan, Michael ^a   Rees, Stephen ^a   Lee, Melanie ^a   Milligan, Graeme ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; CHIMERIC PROTEIN; CYSTEINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; PERTUSSIS TOXIN;

AMINO ACID SEQUENCE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; EMBRYO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; KIDNEY; MOLECULAR SEQUENCE DATA; PERTUSSIS TOXIN; RATS; RECEPTORS, PURINERGIC P1; RECOMBINANT FUSION PROTEINS; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0033596720     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982054f     Document Type: Article

References (24)

1. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649.
2. Wise, A., Watson-Koken, M.-A., Rees, S., Lee, M., and Milligan, G. (1997) Biochem. J. 321, 721-728.
3. Senogles, S. E. (1994) J. Biol. Chem. 269, 23120-23127.
4. Hunt, T. W., Carroll, R. C., and Peralta, E. G. (1994) J. Biol. Chem. 269, 29565-29570.
5. Stiles, G. L. (1992) J. Biol. Chem. 267, 6451-6454.
6. Fredholm, B., and Dunwiddie, T. V. (1988) Trends Pharmacol. Sci. 9, 130-134.
7. Garwins, P., and Fredholm, B. (1992) J. Biol. Chem. 267, 16081-16087.
8. Nakata, H. (1992) Eur. J. Biochem. 206, 171-177.
9. Jockers, R., Linder, M. E., Hohenegger, M., Nanoff, C., Bertin, B., Strosberg, A. D., Marullo, S., and Freissmuth, M. (1994) J. Biol. Chem. 269, 32077-32084.
10. Figler, R. A., Graber, S. G., Lindorfer, M. A., Yasuda, H., Linden, J., and Garrison, J. C. (1996) Mol. Pharmacol. 50, 1587-1595.
11. Green, A., Johnson, J. L., and Milligan, G. (1990) J. Biol. Chem. 265, 5206-5210.
12. McClue, S. J., Selzer, E., Freissmuth, M., and Milligan, G. (1992) Biochem. J. 284, 565-568.
13. Wieland, T., and Jakobs, K. H. (1994) Methods Enzymol. 237, 3-13.
14. Wise, A., Carr, I. C., and Milligan, G. (1997) Biochem. J. 325, 17-21.
15. Wise, A., Carr, I. C., Groarke, D. A., and Milligan, G. (1997) FEBS Lett. 419, 141-146.
16. Wise, A., and Milligan, G. (1997) J. Biol. Chem. 272, 24673-24678.
17. Bertin, B., Freissmuth, M., Jockers, R., Strosberg, A. D., and Marullo, S. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 8827-8831.
18. Medici, R., Bianchi, E., Di Segni, G., and Tocchini-Valentini, G. P. (1997) EMBO J. 16, 7241-7249.
19. Seifert, R., Wenzel-Seifert, K., Lee, T. W., Gether, U., Sanders-Bush, E., and Kobilka, B. K. (1998) J. Biol. Chem. 273, 5109-5116.
20. Kenakin, T. (1995) Trends Pharmacol. Sci. 16, 232-238.
21. Kenakin, T. (1995) Trends Pharmacol. Sci. 16, 188-192.
22. Negishi, M., Harazano, A., Sugimoto, Y., Hazato, A., Kurozumi, S., and Ichikawa, A. (1995) Biochem. Biophys. Res. Commun. 212, 279-285.
23. Berg, K. A., Maayani, S., Goldfarb, J., Scaramellini, C., Leff, P., and Clarke, W. P. (1998) Mol. Pharmacol. 54, 94-104.
24. Eason, M. G., Jacinto, M. T., and Liggett, S. B. (1994) Mol. Pharmacol. 45, 696-702.