-
1
-
-
0024428410
-
Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins
-
van Corven EJ, Groenink A, Jalink K, Eichholtz T, Moolenaar WH. 1989. Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 59:45-54.
-
(1989)
Cell
, vol.59
, pp. 45-54
-
-
Van Corven, E.J.1
Groenink, A.2
Jalink, K.3
Eichholtz, T.4
Moolenaar, W.H.5
-
2
-
-
0026748744
-
Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid
-
van der Bend RL, Brunner J, Jalink K, van Corven EJ, Moolenaar WH, et al. 1992. Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J 11:2495-2501.
-
(1992)
EMBO J
, vol.11
, pp. 2495-2501
-
-
Van Der Bend, R.L.1
Brunner, J.2
Jalink, K.3
Van Corven, E.J.4
Moolenaar, W.H.5
-
3
-
-
0029032202
-
Lysophosphatidic acid, a multifunctional phospholipid messenger
-
Moolenaar WH. 1995. Lysophosphatidic acid, a multifunctional phospholipid messenger. J Biol Chem 270:12949-12952.
-
(1995)
J Biol Chem
, vol.270
, pp. 12949-12952
-
-
Moolenaar, W.H.1
-
4
-
-
0027232391
-
The bioactive phospholipid lysophosphatidic acid is released from activated platelets
-
Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH. 1993. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem J 291:677-680.
-
(1993)
Biochem J
, vol.291
, pp. 677-680
-
-
Eichholtz, T.1
Jalink, K.2
Fahrenfort, I.3
Moolenaar, W.H.4
-
5
-
-
0026795116
-
Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells
-
Tigyi G, Miledi R. 1992. Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells. J Biol Chem 267:21360-21367.
-
(1992)
J Biol Chem
, vol.267
, pp. 21360-21367
-
-
Tigyi, G.1
Miledi, R.2
-
6
-
-
0029836932
-
Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
-
Hecht JH, Weiner JA, Post SR, Chun J. 1996. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J Cell Biol 135:1071-1083.
-
(1996)
J Cell Biol
, vol.135
, pp. 1071-1083
-
-
Hecht, J.H.1
Weiner, J.A.2
Post, S.R.3
Chun, J.4
-
8
-
-
0033604620
-
Bioactive lysophospholipids and their G protein-coupled receptors
-
Moolenaar WH. 1999. Bioactive lysophospholipids and their G protein-coupled receptors. Exp Cell Res 253:230-238.
-
(1999)
Exp Cell Res
, vol.253
, pp. 230-238
-
-
Moolenaar, W.H.1
-
9
-
-
0028021308
-
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho
-
Jalink K, van Corven EJ, Hengeveld T, Morii N, Narumiya S, et al. 1994. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol 126:801-810.
-
(1994)
J Cell Biol
, vol.126
, pp. 801-810
-
-
Jalink, K.1
Van Corven, E.J.2
Hengeveld, T.3
Morii, N.4
Narumiya, S.5
-
10
-
-
0034640285
-
Gelsolin binding and cellular presentation of lysophosphatidic acid
-
Goetzl EJ, Lee H, Azuma T, Stossel TP, Turck CW, et al. 2000. Gelsolin binding and cellular presentation of lysophosphatidic acid. J Biol Chem 275:14573-14578.
-
(2000)
J Biol Chem
, vol.275
, pp. 14573-14578
-
-
Goetzl, E.J.1
Lee, H.2
Azuma, T.3
Stossel, T.P.4
Turck, C.W.5
-
11
-
-
1542359873
-
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
-
Umezu-Goto M, Kishi Y, Taira A, Hama K, Dohmae N, et al. 2002. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol 158:227-233.
-
(2002)
J Cell Biol
, vol.158
, pp. 227-233
-
-
Umezu-Goto, M.1
Kishi, Y.2
Taira, A.3
Hama, K.4
Dohmae, N.5
-
12
-
-
0037131366
-
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
-
Tokumura A, Majima E, Kariya Y, Tominaga K, Kogure K, et al. 2002. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. J Biol Chem 277:39436-39442.
-
(2002)
J Biol Chem
, vol.277
, pp. 39436-39442
-
-
Tokumura, A.1
Majima, E.2
Kariya, Y.3
Tominaga, K.4
Kogure, K.5
-
13
-
-
0036892749
-
Neurobiology of lysophosphatidic acid signaling
-
Fukushima N, Ye X, Chun J. 2002. Neurobiology of lysophosphatidic acid signaling. Neuroscientist 8:540-550.
-
(2002)
Neuroscientist
, vol.8
, pp. 540-550
-
-
Fukushima, N.1
Ye, X.2
Chun, J.3
-
14
-
-
0037162025
-
Lysophospholipids and their G protein-coupled receptors in inflammation and immunity
-
Graler MH, Goetzl EJ. 2002. Lysophospholipids and their G protein-coupled receptors in inflammation and immunity. Biochim Biophys Acta 1582:168-174.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 168-174
-
-
Graler, M.H.1
Goetzl, E.J.2
-
15
-
-
0037016547
-
Lysophosphatidic acid stimulates nuclear and cytoplasmic maturation of golden hamster immature oocytes in vitro via cumulus cells
-
Hinokio K, Yamano S, Nakagawa K, Iraharaa M, Kamada M, et al. 2002. Lysophosphatidic acid stimulates nuclear and cytoplasmic maturation of golden hamster immature oocytes in vitro via cumulus cells. Life Sci 70: 759-767.
-
(2002)
Life Sci
, vol.70
, pp. 759-767
-
-
Hinokio, K.1
Yamano, S.2
Nakagawa, K.3
Iraharaa, M.4
Kamada, M.5
-
16
-
-
1642400249
-
The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: Involvement of P2Y1 and P2Y12 receptors
-
Haseruck N, Erl W, Pandey D, Tigyi G, Ohlmann P, et al. 2004. The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors. Blood 103:2585-2592.
-
(2004)
Blood
, vol.103
, pp. 2585-2592
-
-
Haseruck, N.1
Erl, W.2
Pandey, D.3
Tigyi, G.4
Ohlmann, P.5
-
17
-
-
0035007140
-
Topical application of the phospholipid growth factor lysophosphatidic acid promotes wound healing in vivo
-
Balazs L, Okolicany J, Ferrebee M, Tolley B, Tigyi G. 2001. Topical application of the phospholipid growth factor lysophosphatidic acid promotes wound healing in vivo. Am J Physiol Regul Integr Comp Physiol 280:R466-R472.
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.280
-
-
Balazs, L.1
Okolicany, J.2
Ferrebee, M.3
Tolley, B.4
Tigyi, G.5
-
18
-
-
0037162027
-
Modulation of gastrointestinal wound repair and inflammation by phospholipids
-
Sturm A, Dignass AU. 2002. Modulation of gastrointestinal wound repair and inflammation by phospholipids. Biochim Biophys Acta 1582:282-288.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 282-288
-
-
Sturm, A.1
Dignass, A.U.2
-
19
-
-
0036906499
-
Lysophosphatidic acid, a growth factor-like lipid, in the saliva
-
Sugiura T, Nakane S, Kishimoto S, Waku K, Yoshioka Y, et al. 2002. Lysophosphatidic acid, a growth factor-like lipid, in the saliva. J Lipid Res 43:2049-2055.
-
(2002)
J Lipid Res
, vol.43
, pp. 2049-2055
-
-
Sugiura, T.1
Nakane, S.2
Kishimoto, S.3
Waku, K.4
Yoshioka, Y.5
-
20
-
-
0042887042
-
The emerging role of lysophosphatidic acid in cancer
-
Mills GB, Moolenaar WH. 2003. The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer 3:582-591.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 582-591
-
-
Mills, G.B.1
Moolenaar, W.H.2
-
21
-
-
0033536049
-
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
-
Siess W, Zangl KJ, Essler M, Bauer M, Brandl R, et al. 1999. Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc Natl Acad Sci USA 96: 6931-6936.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6931-6936
-
-
Siess, W.1
Zangl, K.J.2
Essler, M.3
Bauer, M.4
Brandl, R.5
-
22
-
-
0035800886
-
Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids
-
Hayashi K, Takahashi M, Nishida W, Yoshida K, Ohkawa Y, et al. 2001. Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids. Circ Res 89:251-258.
-
(2001)
Circ Res
, vol.89
, pp. 251-258
-
-
Hayashi, K.1
Takahashi, M.2
Nishida, W.3
Yoshida, K.4
Ohkawa, Y.5
-
23
-
-
0141919734
-
Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo
-
Yoshida K, Nishida W, Hayashi K, Ohkawa Y, Ogawa A, et al. 2003. Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo. Circulation 108:1746-1752.
-
(2003)
Circulation
, vol.108
, pp. 1746-1752
-
-
Yoshida, K.1
Nishida, W.2
Hayashi, K.3
Ohkawa, Y.4
Ogawa, A.5
-
24
-
-
12144288490
-
Lysophosphatidic acid induces neointima formation through PPAR(gamma) activation
-
Zhang C, Baker DL, Yasuda S, Makarova N, Balazs L, et al. 2004. Lysophosphatidic acid induces neointima formation through PPAR(gamma) activation. J Exp Med 199:763-774.
-
(2004)
J Exp Med
, vol.199
, pp. 763-774
-
-
Zhang, C.1
Baker, D.L.2
Yasuda, S.3
Makarova, N.4
Balazs, L.5
-
25
-
-
0034551689
-
Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
-
Fukushima N, Weiner JA, Chun J. 2000. Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology. Dev Biol 228:6-18.
-
(2000)
Dev Biol
, vol.228
, pp. 6-18
-
-
Fukushima, N.1
Weiner, J.A.2
Chun, J.3
-
26
-
-
0035924590
-
Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation
-
Campbell DS, Holt CE. 2001. Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32:1013-1026.
-
(2001)
Neuron
, vol.32
, pp. 1013-1026
-
-
Campbell, D.S.1
Holt, C.E.2
-
27
-
-
0037223854
-
Signalling and crosstalk of Rho GTPases in mediating axon guidance
-
Yuan XB, Jin M, Xu X, Song YQ, Wu CP, et al. 2003. Signalling and crosstalk of Rho GTPases in mediating axon guidance. Nat Cell Biol 5: 38-45.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 38-45
-
-
Yuan, X.B.1
Jin, M.2
Xu, X.3
Song, Y.Q.4
Wu, C.P.5
-
28
-
-
0032534510
-
Regulation of astrocyte morphology by RhoA and lysophosphatidic acid
-
Ramakers GJ, Moolenaar WH. 1998. Regulation of astrocyte morphology by RhoA and lysophosphatidic acid. Exp Cell Res 245:252-262.
-
(1998)
Exp Cell Res
, vol.245
, pp. 252-262
-
-
Ramakers, G.J.1
Moolenaar, W.H.2
-
29
-
-
0030048805
-
Serum-induced membrane depolarization in quiescent fibroblasts: Activation of a chloride conductance through the G protein-coupled LPA receptor
-
Postma FR, Jalink K, Hengeveld T, Bot AG, Alblas J, et al. 1996. Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor. EMBO J 15:63-72.
-
(1996)
EMBO J
, vol.15
, pp. 63-72
-
-
Postma, F.R.1
Jalink, K.2
Hengeveld, T.3
Bot, A.G.4
Alblas, J.5
-
30
-
-
0035936480
-
Galpha(13) mediates activation of a depolarizing chloride current that accompanies RhoA activation in both neuronal and nonneuronal cells
-
Postma FR, Jalink K, Hengeveld T, Offermanns S, Moolenaar WH. 2001. Galpha(13) mediates activation of a depolarizing chloride current that accompanies RhoA activation in both neuronal and nonneuronal cells. Curr Biol 11:121-124.
-
(2001)
Curr Biol
, vol.11
, pp. 121-124
-
-
Postma, F.R.1
Jalink, K.2
Hengeveld, T.3
Offermanns, S.4
Moolenaar, W.H.5
-
31
-
-
0033557631
-
Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts
-
Dubin AE, Bahnson T, Weiner JA, Fukushima N, Chun J. 1999. Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts. J Neurosci 19:1371-1381.
-
(1999)
J Neurosci
, vol.19
, pp. 1371-1381
-
-
Dubin, A.E.1
Bahnson, T.2
Weiner, J.A.3
Fukushima, N.4
Chun, J.5
-
32
-
-
0031033652
-
Lysophosphatidic acid increases tight junction permeability in cultured brain endothelial cells
-
Schulze C, Smales C, Rubin LL, Staddon JM. 1997. Lysophosphatidic acid increases tight junction permeability in cultured brain endothelial cells. J Neurochem 68:991-1000.
-
(1997)
J Neurochem
, vol.68
, pp. 991-1000
-
-
Schulze, C.1
Smales, C.2
Rubin, L.L.3
Staddon, J.M.4
-
33
-
-
0033609118
-
Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid
-
Weiner JA, Chun J. 1999. Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid. Proc Natl Acad Sci USA 96:5233-5238.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5233-5238
-
-
Weiner, J.A.1
Chun, J.2
-
34
-
-
0035884770
-
Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling
-
Weiner JA, Fukushima N, Contos JJ, Scherer SS, Chun J. 2001. Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling. J Neurosci 21:7069-7078.
-
(2001)
J Neurosci
, vol.21
, pp. 7069-7078
-
-
Weiner, J.A.1
Fukushima, N.2
Contos, J.J.3
Scherer, S.S.4
Chun, J.5
-
35
-
-
0033601337
-
The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like Tau phosphorylation
-
Sayas CL, Moreno-Flores MT, Avila J, Wandosell F. 1999. The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like Tau phosphorylation. J Biol Chem 274:37046-37052.
-
(1999)
J Biol Chem
, vol.274
, pp. 37046-37052
-
-
Sayas, C.L.1
Moreno-Flores, M.T.2
Avila, J.3
Wandosell, F.4
-
36
-
-
0344011597
-
Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
-
Kingsbury MA, Rehen SK, Contos JJ, Higgins CM, Chun J. 2003. Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding, Nat Neurosci 6:1292-1299.
-
(2003)
Nat Neurosci
, vol.6
, pp. 1292-1299
-
-
Kingsbury, M.A.1
Rehen, S.K.2
Contos, J.J.3
Higgins, C.M.4
Chun, J.5
-
37
-
-
0027513564
-
Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae
-
Jalink K, Moolenaar WH, Van Duijn B. 1993. Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae. Proc Natl Acad Sci USA 90:1857-1861.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1857-1861
-
-
Jalink, K.1
Moolenaar, W.H.2
Van Duijn, B.3
-
38
-
-
2442658976
-
Lysophospholipid G protein-coupled receptors
-
Anliker B, Chun J. 2004. Lysophospholipid G protein-coupled receptors. J Biol Chem.
-
(2004)
J Biol Chem
-
-
Anliker, B.1
Chun, J.2
-
39
-
-
0038152846
-
Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
-
Noguchi K. Ishii S, Shimizu T. 2003. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. J Biol Chem 278:25600-25606.
-
(2003)
J Biol Chem
, vol.278
, pp. 25600-25606
-
-
Noguchi, K.1
Ishii, S.2
Shimizu, T.3
-
40
-
-
0347520943
-
Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1
-
Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, et al. 2003. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1. J Biol Chem 278:400-406.
-
(2003)
J Biol Chem
, vol.278
, pp. 400-406
-
-
Van Leeuwen, F.N.1
Olivo, C.2
Grivell, S.3
Giepmans, B.N.4
Collard, J.G.5
-
41
-
-
0038445491
-
Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway
-
Murph MM, Scaccia LA, Volpicelli LA, Radhakrishna H. 1969. Agonist-induced endocytosis of lysophosphatidic acid-coupled LPA1/EDG-2 receptors via a dynamin2- and Rab5-dependent pathway. J Cell Sci 116: 1969-1980.
-
(1969)
J Cell Sci
, vol.116
, pp. 1969-1980
-
-
Murph, M.M.1
Scaccia, L.A.2
Volpicelli, L.A.3
Radhakrishna, H.4
-
42
-
-
1642279290
-
TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor
-
Xu J, Lai YJ, Lin WC, Lin FT. 2004. TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor. J Biol Chem 279:10459-10468.
-
(2004)
J Biol Chem
, vol.279
, pp. 10459-10468
-
-
Xu, J.1
Lai, Y.J.2
Lin, W.C.3
Lin, F.T.4
-
43
-
-
0034700050
-
Requirement for the IpA1 lysophosphatidic acid receptor gene in normal suckling behavior
-
Contos JJ, Fukushima N, Weiner JA, Kaushal D, Chun J. 2000. Requirement for the IpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc Natl Acad Sci USA 97:13384-13389.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13384-13389
-
-
Contos, J.J.1
Fukushima, N.2
Weiner, J.A.3
Kaushal, D.4
Chun, J.5
-
44
-
-
0037201937
-
Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis
-
McGiffert C, Contos JJ, Friedman B, Chun J. 2002. Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis. FEBS Lett 531:103-108.
-
(2002)
FEBS Lett
, vol.531
, pp. 103-108
-
-
McGiffert, C.1
Contos, J.J.2
Friedman, B.3
Chun, J.4
-
45
-
-
0036786445
-
Characterization of Ipa(2) (Edg4) and Ipa(1)/Ipa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to Ipa(2)
-
Contos JJ, Ishii I, Fukushima N, Kingsbury MA, Ye X, et al. 2002. Characterization of Ipa(2) (Edg4) and Ipa(1)/Ipa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to Ipa(2). Mol Cell Biol 22: 6921-6929.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6921-6929
-
-
Contos, J.J.1
Ishii, I.2
Fukushima, N.3
Kingsbury, M.A.4
Ye, X.5
-
46
-
-
0037125239
-
Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: Possible role of LPA-binding proteins in activation of LPA receptors
-
Hama K, Bandoh K, Kakehi Y, Aoki J, Arai H. 2002. Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors. FEBS Lett 523:187-192.
-
(2002)
FEBS Lett
, vol.523
, pp. 187-192
-
-
Hama, K.1
Bandoh, K.2
Kakehi, Y.3
Aoki, J.4
Arai, H.5
-
47
-
-
0033788829
-
Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system
-
Ishii I, Contos JJ, Fukushima N, Chun J. 2000. Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Mol Pharmacol 58:895-902.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 895-902
-
-
Ishii, I.1
Contos, J.J.2
Fukushima, N.3
Chun, J.4
-
48
-
-
0027411213
-
Pertussis toxin-sensitive activation of p21ras by G protein-coupled- receptor agonists in fibroblasts
-
van Corven EJ, Hordijk PL, Medema RH, Bos JL, Moolenaar WH. 1993. Pertussis toxin-sensitive activation of p21ras by G protein-coupled-receptor agonists in fibroblasts. Proc Natl Acad Sci USA 90:1257-1261.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1257-1261
-
-
Van Corven, E.J.1
Hordijk, P.L.2
Medema, R.H.3
Bos, J.L.4
Moolenaar, W.H.5
-
49
-
-
0035952741
-
Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists
-
Kranenburg O, Moolenaar WH. 2001. Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists. Oncogene 20:1540-1546.
-
(2001)
Oncogene
, vol.20
, pp. 1540-1546
-
-
Kranenburg, O.1
Moolenaar, W.H.2
-
50
-
-
0037077201
-
A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid
-
Yart A, Roche S, Wetzker R, Laffargue M, Tonks N, et al. 2002. A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. J Biol Chem 277:21167-21178.
-
(2002)
J Biol Chem
, vol.277
, pp. 21167-21178
-
-
Yart, A.1
Roche, S.2
Wetzker, R.3
Laffargue, M.4
Tonks, N.5
-
51
-
-
0035952656
-
Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission
-
Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A. 2001. Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 20: 1594-1600.
-
(2001)
Oncogene
, vol.20
, pp. 1594-1600
-
-
Gschwind, A.1
Zwick, E.2
Prenzel, N.3
Leserer, M.4
Ullrich, A.5
-
52
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, et al. 1999. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402:884-888.
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
Leserer, M.4
Abraham, R.5
-
53
-
-
0035827528
-
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade
-
Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, et al. 2001. Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. J Biol Chem 276:20130-20135.
-
(2001)
J Biol Chem
, vol.276
, pp. 20130-20135
-
-
Andreev, J.1
Galisteo, M.L.2
Kranenburg, O.3
Logan, S.K.4
Chiu, E.S.5
-
54
-
-
0346725911
-
Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor
-
Rubio I, Rennert K, Wittig U, Wetzker R. 2003. Ras activation in response to lysophosphatidic acid requires a permissive input from the epidermal growth factor receptor. Biochem J 376:571-576.
-
(2003)
Biochem J
, vol.376
, pp. 571-576
-
-
Rubio, I.1
Rennert, K.2
Wittig, U.3
Wetzker, R.4
-
55
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville S, Hall A. 2002. Rho GTPases in cell biology. Nature 420:629-635.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
56
-
-
0033018626
-
Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells; induction of neurite retraction
-
Kranenburg O, Poland M, van Horck FP, Drechsel D, Hall A, et al. 1999. Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells; induction of neurite retraction. Mol Biol Cell 10:1851-1857.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1851-1857
-
-
Kranenburg, O.1
Poland, M.2
Van Horck, F.P.3
Drechsel, D.4
Hall, A.5
-
57
-
-
0036644975
-
Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
-
Schmidt A, Hall A. 2002. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 16:1587-1609.
-
(2002)
Genes Dev
, vol.16
, pp. 1587-1609
-
-
Schmidt, A.1
Hall, A.2
-
58
-
-
14444288533
-
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells
-
Hirose M, Ishizaki T, Watanabe N, Uehata M, Kranenburg O, et al. 1998. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol 141:1625-1636.
-
(1998)
J Cell Biol
, vol.141
, pp. 1625-1636
-
-
Hirose, M.1
Ishizaki, T.2
Watanabe, N.3
Uehata, M.4
Kranenburg, O.5
-
60
-
-
0030658939
-
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho
-
Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG. 1997. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J Cell Biol 139:797-807.
-
(1997)
J Cell Biol
, vol.139
, pp. 797-807
-
-
Leeuwen, F.N.1
Kain, H.E.2
Kammen, R.A.3
Michiels, F.4
Kranenburg, O.W.5
Collard, J.G.6
-
61
-
-
0032583205
-
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
-
Sander EE, van Delft S, ten Klooster JP, Reid T, van der Kammen RA, et al. 1998. Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol 143:1385-1398.
-
(1998)
J Cell Biol
, vol.143
, pp. 1385-1398
-
-
Sander, E.E.1
Van Delft, S.2
Ten Klooster, J.P.3
Reid, T.4
Van Der Kammen, R.A.5
-
63
-
-
0037422595
-
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist
-
McIntyre TM, Pontsler AV, Suva AR, St Hilaire A, Xu Y, et al. 2003. Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci USA 100: 131-136.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 131-136
-
-
McIntyre, T.M.1
Pontsler, A.V.2
Suva, A.R.3
St. Hilaire, A.4
Xu, Y.5
-
64
-
-
0028986238
-
Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells
-
Fourcade O, Simon MF, Viode C, Rugani N, Leballe F, et al. 1995. Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. Cell 80:919-927.
-
(1995)
Cell
, vol.80
, pp. 919-927
-
-
Fourcade, O.1
Simon, M.F.2
Viode, C.3
Rugani, N.4
Leballe, F.5
-
65
-
-
1042268603
-
Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta
-
Hiramatsu T, Sonoda H, Takanezawa Y, Morikawa R, Ishida M, et al. 2003. Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. J Biol Chem 278:49438-49447.
-
(2003)
J Biol Chem
, vol.278
, pp. 49438-49447
-
-
Hiramatsu, T.1
Sonoda, H.2
Takanezawa, Y.3
Morikawa, R.4
Ishida, M.5
-
66
-
-
0037162023
-
Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids
-
Tokumura A. 2002. Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids. Biochim Biophys Acta 1582:18-25.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 18-25
-
-
Tokumura, A.1
-
67
-
-
0037077199
-
Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood
-
Sano T, Baker D, Virag T, Wada A, Yatomi Y, et al. 2002. Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood. J Biol Chem 277: 21197-21206.
-
(2002)
J Biol Chem
, vol.277
, pp. 21197-21206
-
-
Sano, T.1
Baker, D.2
Virag, T.3
Wada, A.4
Yatomi, Y.5
-
68
-
-
0038043168
-
Autotaxin Is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation
-
Ferry G, Tellier E, Try A, Gres S, Naime I, et al. 2003. Autotaxin Is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. J Biol Chem 278:18162-18169.
-
(2003)
J Biol Chem
, vol.278
, pp. 18162-18169
-
-
Ferry, G.1
Tellier, E.2
Try, A.3
Gres, S.4
Naime, I.5
-
69
-
-
0030842599
-
Autotaxin, tumor motility-stimulating exophosphodiesterase
-
Stracke ML, Clair T, Liotta LA. 1997. Autotaxin, tumor motility-stimulating exophosphodiesterase. Adv Enzyme Regul 37:135-144.
-
(1997)
Adv Enzyme Regul
, vol.37
, pp. 135-144
-
-
Stracke, M.L.1
Clair, T.2
Liotta, L.A.3
-
70
-
-
0034490045
-
Nucleotide pyrophosphatases/phosphodiesterases on the move
-
Bollen M, Gijsbers R, Ceulemans H, Stalmans W, Stefan C. 2000. Nucleotide pyrophosphatases/phosphodiesterases on the move. Crit Rev Biochem Mol Biol 35:393-432.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 393-432
-
-
Bollen, M.1
Gijsbers, R.2
Ceulemans, H.3
Stalmans, W.4
Stefan, C.5
-
71
-
-
0038664247
-
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
-
Goding JW, Grobben B, Siegers H. 2003. Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/ phosphodiesterase family. Biochim Biophys Acta 1638:1-19.
-
(2003)
Biochim Biophys Acta
, vol.1638
, pp. 1-19
-
-
Goding, J.W.1
Grobben, B.2
Siegers, H.3
-
72
-
-
0037434917
-
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site
-
Gijsbers R, Aoki J, Arai H, Bollen M. 2003. The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site. FEBS Lett 538:60-64.
-
(2003)
FEBS Lett
, vol.538
, pp. 60-64
-
-
Gijsbers, R.1
Aoki, J.2
Arai, H.3
Bollen, M.4
-
73
-
-
0344299191
-
Developmental expression analysis of murine autotaxin (ATX)
-
Bachner D, Ahrens M, Betat N, Schroder D, Gross G. 1999. Developmental expression analysis of murine autotaxin (ATX). Mech Dev 84:121-125.
-
(1999)
Mech Dev
, vol.84
, pp. 121-125
-
-
Bachner, D.1
Ahrens, M.2
Betat, N.3
Schroder, D.4
Gross, G.5
-
74
-
-
0030664095
-
Phosphodiesterase I, a novel adhesion molecule and/or cytokine involved in oligodendrocyte function
-
Fuss B, Baba H, Phan T, Tuohy VK, Macklin WB. 1997. Phosphodiesterase I, a novel adhesion molecule and/or cytokine involved in oligodendrocyte function. J Neurosci 17:9095-9103.
-
(1997)
J Neurosci
, vol.17
, pp. 9095-9103
-
-
Fuss, B.1
Baba, H.2
Phan, T.3
Tuohy, V.K.4
Macklin, W.B.5
-
75
-
-
0033983832
-
Characterization of plasma unsaturated lysophosphatidylcholines in human and rat
-
Croset M, Brossard N, Polette A, 2000. Lagarde M. Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. Biochem J 345(Pt 1):61-67.
-
(2000)
Biochem J
, vol.345
, Issue.PART 1
, pp. 61-67
-
-
Croset, M.1
Brossard, N.2
Polette, A.3
Lagarde, M.4
-
76
-
-
0141593615
-
Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate
-
Clair T, Aoki J, Koh E, Bandle RW, Nam SW, et al. 2003. Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate. Cancer Res 63:5446-5453.
-
(2003)
Cancer Res
, vol.63
, pp. 5446-5453
-
-
Clair, T.1
Aoki, J.2
Koh, E.3
Bandle, R.W.4
Nam, S.W.5
-
77
-
-
0035310611
-
Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: A possible role in regulating cardiac function via sphingolipid receptors
-
Liliom K, Sun G, Bunemann M, Virag T, Nusser N, et al. 2001. Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors. Biochem J 355:189-197.
-
(2001)
Biochem J
, vol.355
, pp. 189-197
-
-
Liliom, K.1
Sun, G.2
Bunemann, M.3
Virag, T.4
Nusser, N.5
-
78
-
-
0034642507
-
Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells
-
Nam SW, Clair T, Campo CK, Lee HY, Liotta LA, et al. 2000. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells. Oncogene 19:241-247.
-
(2000)
Oncogene
, vol.19
, pp. 241-247
-
-
Nam, S.W.1
Clair, T.2
Campo, C.K.3
Lee, H.Y.4
Liotta, L.A.5
-
79
-
-
0035884290
-
Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor
-
Nam SW, Clair T, Kim YS, McMarlin A, Schiffmann E, et al. 2001. Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. Cancer Res 61:6938-6944.
-
(2001)
Cancer Res
, vol.61
, pp. 6938-6944
-
-
Nam, S.W.1
Clair, T.2
Kim, Y.S.3
McMarlin, A.4
Schiffmann, E.5
-
80
-
-
0015221368
-
Identification and characterization of a new enzyme of the group "phospholipase D" isolated from Corynebacterium ovis
-
Soucek A, Michalec C, Souckova A. 1971. Identification and characterization of a new enzyme of the group "phospholipase D" isolated from Corynebacterium ovis. Biochim Biophys Acta 227:116-128.
-
(1971)
Biochim Biophys Acta
, vol.227
, pp. 116-128
-
-
Soucek, A.1
Michalec, C.2
Souckova, A.3
-
81
-
-
1642483765
-
Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine
-
van Meeteren LA, Frederiks F, Giepmans BN, Pedrosa MF, Billington SJ, et al. 2004. Spider and bacterial sphingomyelinases D target cellular lysophosphatidic acid receptors by hydrolyzing lysophosphatidylcholine. J Biol Chem 279:10833-10836.
-
(2004)
J Biol Chem
, vol.279
, pp. 10833-10836
-
-
Van Meeteren, L.A.1
Frederiks, F.2
Giepmans, B.N.3
Pedrosa, M.F.4
Billington, S.J.5
-
82
-
-
0027350613
-
Sphingomyelinase D: A pathogenic agent produced by bacteria and arthropods
-
Truett AP III, King LE Jr. 1993. Sphingomyelinase D: a pathogenic agent produced by bacteria and arthropods. Adv Lipid Res 26:275-291.
-
(1993)
Adv Lipid Res
, vol.26
, pp. 275-291
-
-
Truett III, A.P.1
King Jr., L.E.2
-
83
-
-
0030950716
-
Bacterial phospholipases and their role in virulence
-
Songer JG. 1997. Bacterial phospholipases and their role in virulence. Trends Microbiol 5:156-161.
-
(1997)
Trends Microbiol
, vol.5
, pp. 156-161
-
-
Songer, J.G.1
-
84
-
-
0032568216
-
Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways
-
van Dijk MC, Postma F, Hilkmann H, Jalink K, van Blitterswijk WJ, et al. 1998. Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways. Curr Biol 8:386-392.
-
(1998)
Curr Biol
, vol.8
, pp. 386-392
-
-
Van Dijk, M.C.1
Postma, F.2
Hilkmann, H.3
Jalink, K.4
Van Blitterswijk, W.J.5
-
85
-
-
0026521156
-
Metabolic conversion of the biologically active phospholipid, lysophosphatidic acid, in fibroblasts
-
van der Bend RL, de Widt J, van Corven EJ, Moolenaar WH, van Blitterswijk WJ. 1992. Metabolic conversion of the biologically active phospholipid, lysophosphatidic acid, in fibroblasts. Biochim Biophys Acta 1125:110-112.
-
(1992)
Biochim Biophys Acta
, vol.1125
, pp. 110-112
-
-
Van Der Bend, R.L.1
De Widt, J.2
Van Corven, E.J.3
Moolenaar, W.H.4
Van Blitterswijk, W.J.5
-
86
-
-
0032544691
-
Mammalian lipid phosphate phosphohydrolases
-
Brindley DN, Waggoner DW. 1998. Mammalian lipid phosphate phosphohydrolases. J Biol Chem 273:24281-24284.
-
(1998)
J Biol Chem
, vol.273
, pp. 24281-24284
-
-
Brindley, D.N.1
Waggoner, D.W.2
-
87
-
-
0037162091
-
Roles for lipid phosphate phosphatases in regulation of cellular signaling
-
Sciorra VA, Morris AJ. 2002. Roles for lipid phosphate phosphatases in regulation of cellular signaling. Biochim Biophys Acta 1582:45-51.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 45-51
-
-
Sciorra, V.A.1
Morris, A.J.2
-
88
-
-
0038359758
-
A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting
-
Brauer AU, Savaskan NE, Kuhn H, Prehn S, Ninnemann O, et al. 2003. A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Nat Neurosci 6:572-578.
-
(2003)
Nat Neurosci
, vol.6
, pp. 572-578
-
-
Brauer, A.U.1
Savaskan, N.E.2
Kuhn, H.3
Prehn, S.4
Ninnemann, O.5
-
89
-
-
0242290332
-
Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: Studies using chemical inhibitors of lipid phosphate phosphatase activity
-
Smyth SS, Sciorra VA, Sigal YJ, Pamuklar Z, Wang Z, et al. 2003. Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity, J Biol Chem 278:43214-43223.
-
(2003)
J Biol Chem
, vol.278
, pp. 43214-43223
-
-
Smyth, S.S.1
Sciorra, V.A.2
Sigal, Y.J.3
Pamuklar, Z.4
Wang, Z.5
-
90
-
-
0346996444
-
Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level
-
Yue J, Yokoyama K, Balazs L, Baker DL, Smalley D, et al. 2004. Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level. Cell Signal 16:385-399.
-
(2004)
Cell Signal
, vol.16
, pp. 385-399
-
-
Yue, J.1
Yokoyama, K.2
Balazs, L.3
Baker, D.L.4
Smalley, D.5
-
91
-
-
0142074397
-
The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning
-
Escalante-Alcalde D, Hernandez L, Le Stunff H, Maeda R, Lee HS, et al. 2003. The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning. Development 130:4623-4637.
-
(2003)
Development
, vol.130
, pp. 4623-4637
-
-
Escalante-Alcalde, D.1
Hernandez, L.2
Le Stunff, H.3
Maeda, R.4
Lee, H.S.5
-
92
-
-
0032498851
-
Acute loss of cell-cell communication caused by G protein-coupled receptors: A critical role for c-Src
-
Postma FR, Hengeveld T, Alblas J, Giepmans BN, Zondag GC, et al. 1998. Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src. J Cell Biol 140:1199-1209.
-
(1998)
J Cell Biol
, vol.140
, pp. 1199-1209
-
-
Postma, F.R.1
Hengeveld, T.2
Alblas, J.3
Giepmans, B.N.4
Zondag, G.C.5
|