Chimeric Gαi2/Gα13 proteins reveal the structural requirements for the binding and activation of the RGS-like (RGL)-containing Rho guanine nucleotide exchange factors (GEFs) by Gα13

Journal of Biological Chemistry

Volumn 279, Issue 52, 2004, Pages 54283-54290

  Vázquez Prado, José ^a,b   Miyazaki, Hiroshi ^a   Castellone, Maria Domenica ^a   Teramoto, Hidemi ^a   Gutkind, J Silvio ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; ENZYMES; MUTAGENESIS;

BINDING SURFACE; FUNCTIONAL ACTIVATION; MOLECULAR INTERACTIONS; PLASMA MEMBRANES;

PROTEINS;

CHIMERIC PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PDZ PROTEIN; PROTEIN GALPHA13; PROTEIN GALPHAI2; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL MEMBRANE; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; EMBRYO; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; KIDNEY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NIH 3T3 CELLS; POINT MUTATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, GLUTAMATE; RECOMBINANT FUSION PROTEINS; RGS PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 11144225115     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410594200     Document Type: Article

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