Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å

Nature

Volumn 409, Issue 6823, 2001, Pages 1071-1077

  Slep, Kevin C ^a,b   Kercher, Michele A ^a,d   He, Wei ^e   Cowan, Christopher W ^c,e   Wensel, Theodore G ^e   Sigler, Paul B ^a,d  

^a Department of Molecular Biophysics and Biochemistry ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d YALE UNIVERSITY   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHODIESTERASE; RGS PROTEIN; RGS9 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; ENZYME STABILITY; HUMAN; INHIBITION KINETICS; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; AMINO ACID SEQUENCE; ANIMALS; CATTLE; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; GTP-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RGS PROTEINS; ROD OUTER SEGMENTS; SEQUENCE ALIGNMENT; TRANSDUCIN;

VERTEBRATA;

EID: 0035931919     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35059138     Document Type: Article

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