메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 107-127

Effect of administration route on the biodistribution and shedding of replication-deficient HAdV-5: A qualitative modelling approach

Author keywords

Adenovirus; Distribution; Excretion; Gene therapy; Qualitative model; Viral vectors

Indexed keywords

ADENOVIRUS VECTOR;

EID: 77950959733     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652310791111038     Document Type: Review
Times cited : (10)

References (96)
  • 1
    • 0025973255 scopus 로고
    • A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia
    • Ginsberg HS, Moldawer LL, Sehgal PB, et al. A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia. Proc Natl Acad Sci USA 1991; 88: 1651-1655.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1651-1655
    • Ginsberg, H.S.1    Moldawer, L.L.2    Sehgal, P.B.3
  • 6
    • 0013584225 scopus 로고
    • Adenovirus as a model of disease
    • L-BUPG. Russel W, Ed. New York: Cambridge University press
    • Ginsberg H.S. L-BUPG. Adenovirus as a model of disease. Russel W, Ed. Molecular basis of virus disease. New York: Cambridge University press 1987; pp. 245-258.
    • (1987) Molecular Basis of Virus Disease , pp. 245-258
    • Ginsberg, H.S.1
  • 7
    • 70350442259 scopus 로고    scopus 로고
    • The influence of innate and pre-existing immunity on adenovirus therapy
    • Zaiss AK, Machado HB, Herschman HR. The influence of innate and pre-existing immunity on adenovirus therapy. J Cell Biochem 2009; 108: 778-790.
    • (2009) J Cell Biochem , vol.108 , pp. 778-790
    • Zaiss, A.K.1    Machado, H.B.2    Herschman, H.R.3
  • 8
    • 0032573158 scopus 로고    scopus 로고
    • Adenoviral-mediated gene transfer in lymphocytes
    • Leon RP, Hedlund T, Meech SJ, et al. Adenoviral-mediated gene transfer in lymphocytes. Proc Natl Acad Sci USA 1998; 95: 13159-13164.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13159-13164
    • Leon, R.P.1    Hedlund, T.2    Meech, S.J.3
  • 11
    • 34548236927 scopus 로고    scopus 로고
    • Intracellular trafficking of adenovirus: Many means to many ends
    • Leopold PL, Crystal RG. Intracellular trafficking of adenovirus: many means to many ends. Adv Drug Deliv Rev 2007; 59: 810-821.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 810-821
    • Leopold, P.L.1    Crystal, R.G.2
  • 12
    • 0028981979 scopus 로고
    • Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway
    • Goldman MJ, Wilson JM. Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway. J Virol 1995; 69: 5951-5958.
    • (1995) J Virol , vol.69 , pp. 5951-5958
    • Goldman, M.J.1    Wilson, J.M.2
  • 13
    • 0028987384 scopus 로고
    • Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
    • Huang S, Endo RI, Nemerow GR. Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J Virol 1995; 69: 2257-2263.
    • (1995) J Virol , vol.69 , pp. 2257-2263
    • Huang, S.1    Endo, R.I.2    Nemerow, G.R.3
  • 14
    • 0032828285 scopus 로고    scopus 로고
    • Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers
    • Fechner H, Haack A, Wang H, et al. Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers. Gene Ther 1999; 6: 1520-1535.
    • (1999) Gene Ther , vol.6 , pp. 1520-1535
    • Fechner, H.1    Haack, A.2    Wang, H.3
  • 16
    • 0035420192 scopus 로고    scopus 로고
    • The mechanism of the growth-inhibitory effect of coxsackie and adenovirus receptor (CAR) on human bladder cancer: A functional analysis of car protein structure
    • Okegawa T, Pong RC, Li Y, Bergelson JM, Sagalowsky AI, Hsieh JT. The mechanism of the growth-inhibitory effect of coxsackie and adenovirus receptor (CAR) on human bladder cancer: a functional analysis of car protein structure. Cancer Res 2001; 61: 6592-6600. (Pubitemid 32783269)
    • (2001) Cancer Research , vol.61 , Issue.17 , pp. 6592-6600
    • Okegawa, T.1    Pong, R.-C.2    Li, Y.3    Bergelson, J.M.4    Sagalowsky, A.I.5    Hsieh, J.-T.6
  • 18
    • 23844542268 scopus 로고    scopus 로고
    • The influence of adenovirus fiber structure and function on vector development for gene therapy
    • DOI 10.1016/j.ymthe.2005.05.008, PII S1525001605002029
    • Nicklin SA, Wu E, Nemerow GR, Baker AH. The influence of adenovirus fiber structure and function on vector development for gene therapy. Mol Ther 2005; 12: 384-393. (Pubitemid 41150124)
    • (2005) Molecular Therapy , vol.12 , Issue.3 , pp. 384-393
    • Nicklin, S.A.1    Wu, E.2    Nemerow, G.R.3    Baker, A.H.4
  • 21
    • 34548164748 scopus 로고    scopus 로고
    • Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: Fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5
    • Waddington SN, Parker AL, Havenga MJ, et al. Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. J Virol 2007; 81: 9568-9571.
    • (2007) J Virol , vol.81 , pp. 9568-9571
    • Waddington, S.N.1    Parker, A.L.2    Havenga, M.J.3
  • 22
    • 34250191828 scopus 로고    scopus 로고
    • Current advances and future challenges in adenoviral vector biology and targeting
    • DOI 10.2174/156652307780859062
    • Campos SK, Barry MA. Current advances and future challenges in Adenoviral vector biology and targeting. Curr Gene Ther 2007; 7: 189-204. (Pubitemid 46902201)
    • (2007) Current Gene Therapy , vol.7 , Issue.3 , pp. 189-204
    • Campos, S.K.1    Barry, M.A.2
  • 23
    • 34547806055 scopus 로고    scopus 로고
    • Adenovirus vectors composed of subgroup B adenoviruses
    • DOI 10.2174/156652307781369137
    • Sakurai F, Kawabata K, Mizuguchi H. Adenovirus vectors composed of subgroup B adenoviruses. Curr Gene Ther 2007; 7 : 229-238. (Pubitemid 47232955)
    • (2007) Current Gene Therapy , vol.7 , Issue.4 , pp. 229-238
    • Sakurai, F.1    Kawabata, K.2    Mizuguchi, H.3
  • 24
    • 33645747062 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans and viral vectors: Ally or foe?
    • Vivčs RR, Lortat-Jacob H, Fender P. Heparan sulphate proteoglycans and viral vectors : ally or foe? Curr Gene Ther 2006; 6: 35-44.
    • (2006) Curr Gene Ther , vol.6 , pp. 35-44
    • Vivčs, R.R.1    Lortat-Jacob, H.2    Fender, P.3
  • 25
    • 54749133105 scopus 로고    scopus 로고
    • Advances in helper-dependent adenoviral vector research
    • Segura MM, Alba R, Bosch A, Chillón M. Advances in helper-dependent adenoviral vector research. Curr Gene Ther 2008; 8: 222-235.
    • (2008) Curr Gene Ther , vol.8 , pp. 222-235
    • Segura, M.M.1    Alba, R.2    Bosch, A.3    Chillón, M.4
  • 28
    • 45749101234 scopus 로고    scopus 로고
    • International efforts for recombinant adeno-associated viral vector reference standards
    • DOI 10.1038/mt.2008.125, PII MT2008125
    • Moullier P, Snyder RO. International efforts for recombinant adeno-associated viral vector reference standards. Mol Ther 2008; 16: 1185-1188. (Pubitemid 351866048)
    • (2008) Molecular Therapy , vol.16 , Issue.7 , pp. 1185-1188
    • Moullier, P.1    Snyder, R.O.2
  • 29
    • 5444276384 scopus 로고    scopus 로고
    • Gene transfer vector biodistribution: Pivotal safety studies in clinical gene therapy development
    • DOI 10.1038/sj.gt.3302378
    • Gonin P, Gaillard C. Gene transfer vector biodistribution: pivotal safety studies in clinical gene therapy development. Gene Ther 2004; 11 (Suppl 1): S98-S108. (Pubitemid 39359454)
    • (2004) Gene Therapy , vol.11 , Issue.SUPPL. 1
    • Gonin, P.1    Gaillard, C.2
  • 30
    • 77249118915 scopus 로고    scopus 로고
    • Effect of administration route on biodistribution and shedding of replication-deficient viral vectors used in gene therapy: A literature study
    • Brandon E, Tiesjema B, van Eijkeren J, Hermsen H. Effect of administration route on biodistribution and shedding of replication-deficient viral vectors used in gene therapy: a literature study. RIVM report no 320001001. 2008.
    • (2008) RIVM Report No 320001001
    • Brandon, E.1    Tiesjema, B.2    Van Eijkeren, J.3    Hermsen, H.4
  • 31
    • 33845754406 scopus 로고    scopus 로고
    • Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction
    • Johnson M, Huyn S, Burton J, Sato M, Wu L. Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction. Hum Gene Ther 2006; 17: 1262-1269.
    • (2006) Hum Gene Ther , vol.17 , pp. 1262-1269
    • Johnson, M.1    Huyn, S.2    Burton, J.3    Sato, M.4    Wu, L.5
  • 32
    • 70350570602 scopus 로고    scopus 로고
    • Development and application of a real-time PCR method for pharmacokinetic and biodistribution studies of recombinant adenovirus
    • Xu XX, Shui X, Chen ZH, Shan CQ, Hou YN, Cheng YG. Development and application of a real-time PCR method for pharmacokinetic and biodistribution studies of recombinant adenovirus. Mol Biotechnol 2009; 43: 130-137.
    • (2009) Mol Biotechnol , vol.43 , pp. 130-137
    • Xu, X.X.1    Shui, X.2    Chen, Z.H.3    Shan, C.Q.4    Hou, Y.N.5    Cheng, Y.G.6
  • 33
    • 0030943732 scopus 로고    scopus 로고
    • Macrophage depletion increases the safety, efficacy and persistence of adenovirusmediated gene transfer in vivo
    • Kuzmin AI, Finegold MJ, Eisensmith RC. Macrophage depletion increases the safety, efficacy and persistence of adenovirusmediated gene transfer in vivo. Gene Ther 1997; 4: 309-316.
    • (1997) Gene Ther , vol.4 , pp. 309-316
    • Kuzmin, A.I.1    Finegold, M.J.2    Eisensmith, R.C.3
  • 34
    • 36348940985 scopus 로고    scopus 로고
    • Comparison of adenoviruses from species B, C, e, and f after intravenous delivery
    • Stone D, Liu Y, Li ZY, Tuve S, Strauss R, Lieber A. Comparison of adenoviruses from species B, C, e, and f after intravenous delivery. Mol Ther 2007; 15: 2146-2153.
    • (2007) Mol Ther , vol.15 , pp. 2146-2153
    • Stone, D.1    Liu, Y.2    Li, Z.Y.3    Tuve, S.4    Strauss, R.5    Lieber, A.6
  • 35
    • 0034182939 scopus 로고    scopus 로고
    • Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: Involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression
    • Kosuga M, Takahashi S, Sasaki K, et al. Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression. Mol Ther 2000; 1: 406-413.
    • (2000) Mol Ther , vol.1 , pp. 406-413
    • Kosuga, M.1    Takahashi, S.2    Sasaki, K.3
  • 36
    • 0042622200 scopus 로고    scopus 로고
    • Characterization of adenovirus p21 gene transfer, biodistribution, and immune response after local ocular delivery in New Zealand white rabbits
    • DOI 10.1016/S0014-4835(03)00122-2
    • Wen SF, Chen Z, Nery J, Faha B . Characterization of adenovirus p21 gene transfer, biodistribution, and immune response after local ocular delivery in New Zealand white rabbits. Exp Eye Res 2003; 77: 355-365. (Pubitemid 36952374)
    • (2003) Experimental Eye Research , vol.77 , Issue.3 , pp. 355-365
    • Wen, S.F.1    Chen, Z.2    Nery, J.3    Faha, B.4
  • 37
    • 0033729780 scopus 로고    scopus 로고
    • Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods
    • Hiltunen MO, Turunen MP, Turunen AM, et al. Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods. FASEB J 2000; 14: 2230-2236.
    • (2000) FASEB J , vol.14 , pp. 2230-2236
    • Hiltunen, M.O.1    Turunen, M.P.2    Turunen, A.M.3
  • 41
    • 20844436457 scopus 로고    scopus 로고
    • Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons
    • DOI 10.1089/hum.2005.16.664
    • Ni S, Bernt K, Gaggar A, Li ZY, Kiem HP, Lieber A. Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons. Hum Gene Ther 2005; 16: 664-677. (Pubitemid 40864267)
    • (2005) Human Gene Therapy , vol.16 , Issue.6 , pp. 664-677
    • Ni, S.1    Bernt, K.2    Gaggar, A.3    Li, Z.-Y.4    Kiem, H.-P.5    Lieber, A.6
  • 42
    • 72949092147 scopus 로고    scopus 로고
    • Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells
    • Koski A, Rajecki M, Guse K, et al. Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells. J Gene Med 2009; 11: 966-977.
    • (2009) J Gene Med , vol.11 , pp. 966-977
    • Koski, A.1    Rajecki, M.2    Guse, K.3
  • 43
    • 0034830243 scopus 로고    scopus 로고
    • CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors
    • DOI 10.1038/sj.gt.3301515
    • Alemany R, Curiel DT. CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors. Gene Ther 2001; 8: 1347-1353. (Pubitemid 32834304)
    • (2001) Gene Therapy , vol.8 , Issue.17 , pp. 1347-1353
    • Alemany, R.1    Curiel, D.T.2
  • 44
    • 0033161662 scopus 로고    scopus 로고
    • Biodistribution of an adenoviral vector carrying the luciferase reporter gene following intravesical or intravenous administration to a mouse
    • Wood M, Perrotte P, Onishi E, et al. Biodistribution of an adenoviral vector carrying the luciferase reporter gene following intravesical or intravenous administration to a mouse. Cancer Gene Ther 1999; 6: 367-372. (Pubitemid 129667809)
    • (1999) Cancer Gene Therapy , vol.6 , Issue.4 , pp. 367-372
    • Wood, M.1    Perrotte, P.2    Onishi, E.3    Harper, M.E.4    Dinney, C.5    Pagliaro, L.6    Wilson, D.R.7
  • 45
    • 0034566905 scopus 로고    scopus 로고
    • Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo
    • Hackett NR, El Sawy T, Lee LY, et al. Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo. Mol Ther 2000; 2: 649-656.
    • (2000) Mol Ther , vol.2 , pp. 649-656
    • Hackett, N.R.1    El Sawy, T.2    Lee, L.Y.3
  • 46
    • 0036765049 scopus 로고    scopus 로고
    • Peptide-retargeted adenovirus encoding a tissue inhibitor of metalloproteinase-1 decreases restenosis after intravascular gene transfer
    • Turunen MP, Puhakka HL, Koponen JK, et al. Peptide-retargeted adenovirus encoding a tissue inhibitor of metalloproteinase-1 decreases restenosis after intravascular gene transfer. Mol Ther 2002; 6: 306-312.
    • (2002) Mol Ther , vol.6 , pp. 306-312
    • Turunen, M.P.1    Puhakka, H.L.2    Koponen, J.K.3
  • 47
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • Alemany R, Suzuki K, Curiel DT. Blood clearance rates of adenovirus type 5 in mice. J Gen Virol 2000; 81: 2605-2609.
    • (2000) J Gen Virol , vol.81 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 49
    • 67650327240 scopus 로고    scopus 로고
    • Multiple hepatic arterial injections of recombinant adenovirus p53 and 5-fluorouracil after transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: A pilot phase II trial
    • Tian G, Liu J, Zhou JS, Chen W . Multiple hepatic arterial injections of recombinant adenovirus p53 and 5-fluorouracil after transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: a pilot phase II trial. Anticancer Drugs 2009; 20: 389-395.
    • (2009) Anticancer Drugs , vol.20 , pp. 389-395
    • Tian, G.1    Liu, J.2    Zhou, J.S.3    Chen, W.4
  • 52
    • 26644444774 scopus 로고    scopus 로고
    • Arteriogenic gene therapy in patients with unreconstructable critical limb ischemia: A randomized, placebo-controlled clinical trial of adenovirus 5-delivered fibroblast growth factor-4
    • DOI 10.1089/hum.2005.16.1202
    • Matyas L, Schulte KL, Dormandy JA, et al. Arteriogenic gene therapy in patients with unreconstructable critical limb ischemia: a randomized, placebo-controlled clinical trial of adenovirus 5-delivered fibroblast growth factor-4. Hum Gene Ther 2005; 16: 1202-1211. (Pubitemid 41443712)
    • (2005) Human Gene Therapy , vol.16 , Issue.10 , pp. 1202-1211
    • Matyas, L.1    Schulte, K.-L.2    Dormandy, J.A.3    Norgren, L.4    Sowade, O.5    Grotzbach, G.6    Palmer-Kazen, U.7    Rubanyi, G.M.8    Wahlberg, E.9
  • 55
    • 0029100239 scopus 로고
    • A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
    • Knowles MR, Hohneker KW, Zhou Z, et al. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N Engl J Med 1995; 333: 823-831.
    • (1995) N Engl J Med , vol.333 , pp. 823-831
    • Knowles, M.R.1    Hohneker, K.W.2    Zhou, Z.3
  • 56
    • 0033544951 scopus 로고    scopus 로고
    • A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis
    • Zuckerman JB, Robinson CB, McCoy KS, et al. A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis. Hum Gene Ther 1999; 10: 2973-2985.
    • (1999) Hum Gene Ther , vol.10 , pp. 2973-2985
    • Zuckerman, J.B.1    Robinson, C.B.2    McCoy, K.S.3
  • 57
    • 51649128840 scopus 로고    scopus 로고
    • Phase I study of adenovirus p53 administered by bronchoalveolar lavage in patients with bro chioloalveolar cell lung carcinoma: ECOG 6597
    • Keedy V, Wang W, Schiller J, et al. Phase I study of adenovirus p53 administered by bronchoalveolar lavage in patients with bro chioloalveolar cell lung carcinoma: ECOG 6597. J Clin Oncol 2008; 26: 4166-4171.
    • (2008) J Clin Oncol , vol.26 , pp. 4166-4171
    • Keedy, V.1    Wang, W.2    Schiller, J.3
  • 58
    • 0031580609 scopus 로고    scopus 로고
    • Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract
    • Worgall S, Leopold PL, Wolff G, Ferris B, Van Roijen N, Crystal RG. Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract. Hum Gene Ther 1997; 8: 1675-1684. (Pubitemid 28031586)
    • (1997) Human Gene Therapy , vol.8 , Issue.14 , pp. 1675-1684
    • Worgall, S.1
  • 59
    • 3543071097 scopus 로고    scopus 로고
    • A phase I study of Adp53 (INGN 201; ADVEXIN) for patients with platinum- and paclitaxel-resistant epithelial ovarian cancer
    • Wolf JK, Bodurka DC, Gano JB, et al. A phase I study of Adp53 (INGN 201; ADVEXIN) for patients with platinum- and paclitaxel-resistant epithelial ovarian cancer. Gynecol Oncol 2004; 94: 442-448.
    • (2004) Gynecol Oncol , vol.94 , pp. 442-448
    • Wolf, J.K.1    Bodurka, D.C.2    Gano, J.B.3
  • 62
    • 18944387569 scopus 로고    scopus 로고
    • Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery
    • DOI 10.1038/sj.bjc.6602494
    • Wang Y, Yang Z, Liu S, et al. Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery. Br J Cancer 2005; 92: 1414-1420. (Pubitemid 40705008)
    • (2005) British Journal of Cancer , vol.92 , Issue.8 , pp. 1414-1420
    • Wang, Y.1    Yang, Z.2    Liu, S.3    Kon, T.4    Krol, A.5    Li, C.-Y.6    Yuan, F.7
  • 67
    • 0032971662 scopus 로고    scopus 로고
    • Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: Results of a phase 1 clinical trial
    • Stewart AK, Lassam NJ, Quirt IC, et al. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial. Gene Ther 1999; 6: 350-363.
    • (1999) Gene Ther , vol.6 , pp. 350-363
    • Stewart, A.K.1    Lassam, N.J.2    Quirt, I.C.3
  • 73
    • 65349097471 scopus 로고    scopus 로고
    • Dynamic distribution and expression in vivo of the human interferon gamma gene delivered by adenoviral vector
    • Wu J, Xiao X, Jia H, et al. Dynamic distribution and expression in vivo of the human interferon gamma gene delivered by adenoviral vector. BMC Cancer 2009; 9: 55-61.
    • (2009) BMC Cancer , vol.9 , pp. 55-61
    • Wu, J.1    Xiao, X.2    Jia, H.3
  • 74
    • 0034136802 scopus 로고    scopus 로고
    • Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors
    • Trask TW, Trask RP, Aguilar-Cordova E, et al. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther 2000; 1: 195-203.
    • (2000) Mol Ther , vol.1 , pp. 195-203
    • Trask, T.W.1    Trask, R.P.2    Aguilar-Cordova, E.3
  • 75
    • 0346243603 scopus 로고    scopus 로고
    • Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: Preliminary results of a phase I trial in patients with recurrent malignant gliomas
    • DOI 10.1023/B:NEON.0000003657.95085.56
    • Germano IM, Fable J, Gultekin SH, Silvers A. Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas. J Neurooncol 2003; 65: 279-289. (Pubitemid 37526820)
    • (2003) Journal of Neuro-Oncology , vol.65 , Issue.3 , pp. 279-289
    • Germano, I.M.1    Fable, J.2    Gultekin, S.H.3    Silvers, A.4
  • 77
    • 10744227813 scopus 로고    scopus 로고
    • Phase I Study of Replication-Competent Adenovirus-Mediated Double-Suicide Gene Therapy in Combination with Conventional-Dose Three-Dimensional Conformal Radiation Therapy for the Treatment of Newly Diagnosed, Intermediate- To High-Risk Prostate Cancer
    • Freytag SO, Stricker H, Pegg J, et al. Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate-to high-risk prostate cancer. Cancer Res 2003; 63: 7497-7506. (Pubitemid 37413494)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7497-7506
    • Freytag, S.O.1    Stricker, H.2    Pegg, J.3    Paielli, D.4    Pradhan, D.G.5    Peabody, J.6    Deperalta-Venturina, M.7    Xia, X.8    Brown, S.9    Lu, M.10    Kim, J.H.11
  • 79
    • 0033135221 scopus 로고    scopus 로고
    • In situ gene therapy for adenocarcinoma of the prostate: A phase I clinical trial
    • Herman JR, Adler HL, Aguilar-Cordova E, et al. In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial. Hum Gene Ther 1999; 10: 1239-1249.
    • (1999) Hum Gene Ther , vol.10 , pp. 1239-1249
    • Herman, J.R.1    Adler, H.L.2    Aguilar-Cordova, E.3
  • 80
    • 0037812853 scopus 로고    scopus 로고
    • Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir
    • DOI 10.1016/S1525-0016(03)00100-X
    • Smitt PS, Driesse M, Wolbers J, Kros M, Avezaat C. Treatment of relapsed malignant glioma with an adenoviral vector containing the herpes simplex thymidine kinase gene followed by ganciclovir. Mol Ther 2003; 7: 851-858. (Pubitemid 36790262)
    • (2003) Molecular Therapy , vol.7 , Issue.6 , pp. 851-858
    • Smitt, P.S.1    Driesse, M.2    Wolbers, J.3    Kros, M.4    Avezaat, C.5
  • 81
    • 85047697641 scopus 로고    scopus 로고
    • Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: Biological and clinical results
    • Lang FF, Bruner JM, Fuller GN, et al. Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results. J Clin Oncol 2003; 21: 2508-2518.
    • (2003) J Clin Oncol , vol.21 , pp. 2508-2518
    • Lang, F.F.1    Bruner, J.M.2    Fuller, G.N.3
  • 82
    • 0034329438 scopus 로고    scopus 로고
    • Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses
    • Sandmair AM, Loimas S, Puranen P, et al. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum Gene Ther 2000; 11: 2197-2205.
    • (2000) Hum Gene Ther , vol.11 , pp. 2197-2205
    • Sandmair, A.M.1    Loimas, S.2    Puranen, P.3
  • 84
    • 2442718933 scopus 로고    scopus 로고
    • Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenecity profiles favorable for clinical use1
    • DOI 10.1016/j.ymthe.2004.02.018
    • Gu DL, Nguyen T, Gonzalez AM, et al. Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use. Mol Ther 2004; 9: 699-711. (Pubitemid 38660423)
    • (2004) Molecular Therapy , vol.9 , Issue.5 , pp. 699-711
    • Gu, D.-L.1    Nguyen, T.2    Gonzalez, A.M.3    Printz, M.A.4    Pierce, G.F.5    Sosnowski, B.A.6    Phillips, M.L.7    Chandler, L.A.8
  • 85
    • 34347391234 scopus 로고    scopus 로고
    • SCH 412499: Biodistribution and safety of an adenovirus containing P21(WAF-1/CIP-1) following subconjunctival injection in Cynomolgus monkeys
    • Veneziale RW, Bral CM, Sinha DP, et al. SCH 412499: biodistribution and safety of an adenovirus containing P21(WAF-1/CIP-1) following subconjunctival injection in Cynomolgus monkeys. Cutan Ocul Toxicol 2007; 26: 83-105.
    • (2007) Cutan Ocul Toxicol , vol.26 , pp. 83-105
    • Veneziale, R.W.1    Bral, C.M.2    Sinha, D.P.3
  • 86
    • 32944481724 scopus 로고    scopus 로고
    • Adenoviral vectordelivered pigment epithelium-derived factor for neovascular age-related macular degeneration: Results of a phase I clinical trial
    • Campochiaro PA, Nguyen QD, Shah SM, et al. Adenoviral vectordelivered pigment epithelium-derived factor for neovascular age-related macular degeneration: results of a phase I clinical trial. Hum Gene Ther 2006; 17: 167-176.
    • (2006) Hum Gene Ther , vol.17 , pp. 167-176
    • Campochiaro, P.A.1    Nguyen, Q.D.2    Shah, S.M.3
  • 87
    • 33645110519 scopus 로고    scopus 로고
    • Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland
    • Zheng C, Voutetakis A, Kok MR, et al. Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland. Oral Dis 2006; 12: 137-144.
    • (2006) Oral Dis , vol.12 , pp. 137-144
    • Zheng, C.1    Voutetakis, A.2    Kok, M.R.3
  • 88
    • 33751008677 scopus 로고    scopus 로고
    • Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland
    • DOI 10.1089/hum.2006.17.1122
    • Zheng C, Goldsmith CM, Mineshiba F, et al. Toxicity and biodistribution of a first-generation recombinant adenoviral vector, encoding aquaporin-1, after retroductal delivery to a single rat submandibular gland. Hum Gene Ther 2006; 17: 1122-1133. (Pubitemid 44749713)
    • (2006) Human Gene Therapy , vol.17 , Issue.11 , pp. 1122-1133
    • Zheng, C.1    Goldsmith, C.M.2    Mineshiba, F.3    Chiorini, J.A.4    Kerr, A.5    Wenk, M.L.6    Vallant, M.7    Irwin, R.D.8    Baum, B.J.9
  • 89
    • 66149096522 scopus 로고    scopus 로고
    • Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use
    • Chang PC, Cirelli JA, Jin Q, et al. Adenovirus encoding human platelet-derived growth factor-B delivered to alveolar bone defects exhibits safety and biodistribution profiles favorable for clinical use. Hum Gen Ther 2009; 20: 486-496.
    • (2009) Hum Gen Ther , vol.20 , pp. 486-496
    • Chang, P.C.1    Cirelli, J.A.2    Jin, Q.3
  • 91
    • 1842636251 scopus 로고    scopus 로고
    • Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo
    • DOI 10.1089/104303404322959551
    • Wang AY, Peng PD, Ehrhardt A, Storm TA, Kay MA. Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo. Hum Gene Ther 2004; 15: 405-413. (Pubitemid 38469782)
    • (2004) Human Gene Therapy , vol.15 , Issue.4 , pp. 405-413
    • Wang, A.Y.1    Peng, P.D.2    Ehrhardt, A.3    Storm, T.A.4    Kay, M.A.5
  • 92
    • 62249168240 scopus 로고    scopus 로고
    • Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting
    • Lenaerts L, McVey JH, Baker AH, et al. Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting. J Gene Med 2009; 11: 119-127.
    • (2009) J Gene Med , vol.11 , pp. 119-127
    • Lenaerts, L.1    McVey, J.H.2    Baker, A.H.3
  • 93
    • 56849102958 scopus 로고    scopus 로고
    • Different tropism of adenoviruses and adeno-associated viruses to corneal cells: Implications for corneal gene therapy
    • Liu J, Saghizadeh M, Tuli SS, et al. Different tropism of adenoviruses and adeno-associated viruses to corneal cells: implications for corneal gene therapy. Mol Vis 2008; 14: 2087-2096.
    • (2008) Mol Vis , vol.14 , pp. 2087-2096
    • Liu, J.1    Saghizadeh, M.2    Tuli, S.S.3
  • 94
    • 0032853699 scopus 로고    scopus 로고
    • Immune responses to adenovirus and adeno-associated virus in humans
    • DOI 10.1038/sj.gt.3300994
    • Chirmule N, Propert K, Magosin S, Qian Y, Qian R, Wilson J. Immune responses to adenovirus and adeno-associated virus in humans. Gene Ther 1999; 6: 1574-1583. (Pubitemid 29465516)
    • (1999) Gene Therapy , vol.6 , Issue.9 , pp. 1574-1583
    • Chirmule, N.1    Propert, K.J.2    Magosin, S.A.3    Qian, Y.4    Qian, R.5    Wilson, J.M.6
  • 95
    • 0036202298 scopus 로고    scopus 로고
    • Critical issues in gene therapy for neurologic disease
    • DOI 10.1089/10430340252837198
    • Hsich G, Sena-Esteves M, Breakefield XO. Critical issues in gene therapy for neurologic disease. Hum Gene Ther 2002; 13: 579-604. (Pubitemid 34264310)
    • (2002) Human Gene Therapy , vol.13 , Issue.5 , pp. 579-604
    • Hsich, G.1    Sena-Esteves, M.2    Breakefield, X.O.3
  • 96
    • 33847791626 scopus 로고    scopus 로고
    • Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model
    • DOI 10.1038/sj.gt.3302888, PII 3302888
    • Tang Y, Han T, Everts M, et al. Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model. Gene Ther 2007; 14: 523-532. (Pubitemid 46390925)
    • (2007) Gene Therapy , vol.14 , Issue.6 , pp. 523-532
    • Tang, Y.1    Han, T.2    Everts, M.3    Zhu, Z.B.4    Gillespie, G.Y.5    Curiel, D.T.6    Wu, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.