Adenovirus-mediated gene therapy for mucopolysaccharidosis VII: Involvement of cross-correction in wide-spread distribution of the gene products and long-term effects of CTLA-4Ig coexpression

Molecular Therapy

Volumn 1, Issue 5, 2000, Pages 406-413

  Kosuga, Motomichi ^a,b   Takahashi, Satori ^a,c   Sasaki, Kyoko ^a   Li, Xiao Kang ^a   Fujino, Masayuki ^a   Hamada, Hirofumi ^d   Suzuki, Seiichi ^a   Yamada, Masao ^a   Matsuo, Nobutake ^b   Okuyama, Torayuki ^a,b  

^a Natl Childrens Med Res Ctr   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d CANCER INSTITUTE   (Japan)

Author keywords

Adenovirus; CTLA 4Ig; Gene therapy; Mucopolysaccharidosis type VII

Indexed keywords

ADENOVIRIDAE; MURINAE;

ABATACEPT; ANTIBODY CONJUGATE; BETA GALACTOSIDASE; BETA GLUCURONIDASE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; LEUKOCYTE ANTIGEN; PRIMER DNA; SOMATOMEDIN B RECEPTOR; VIRUS DNA;

ADENOVIRUS; ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION; GENE THERAPY; GENE VECTOR; GENETICS; GENOTYPE; HUMAN; KIDNEY; LIVER; LUNG; METABOLISM; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; PATHOLOGY; SPLEEN;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BETA-GALACTOSIDASE; CELLS, CULTURED; DNA PRIMERS; DNA, VIRAL; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GENOTYPE; GLUCURONIDASE; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULIN FC FRAGMENTS; KIDNEY; LIVER; LUNG; MICE; MICE, INBRED C57BL; MUCOPOLYSACCHARIDOSIS VII; RECEPTOR, IGF TYPE 2; RECOMBINANT FUSION PROTEINS; SPLEEN;

EID: 0034182939     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0067     Document Type: Article

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