-
1
-
-
0038621437
-
Gene- and cell-based therapeutics for type I diabetes mellitus
-
BOTTINO, R., LEMARCHAND, P., TRUCCO, M., and GIANNOUKAKIS, N. (2003). Gene-and cell-based therapeutics for type I diabetes mellitus. Gene Ther. 10, 875-889.
-
(2003)
Gene Ther.
, vol.10
, pp. 875-889
-
-
Bottino, R.1
Lemarchand, P.2
Trucco, M.3
Giannoukakis, N.4
-
2
-
-
0035401096
-
Adenoviral vector-mediated gene transfer for human gene therapy
-
BREYER, B., JIANG, W., CHENG, H., ZHOU, L., PAUL, R., FENG, T., and HE, T.C. (2001). Adenoviral vector-mediated gene transfer for human gene therapy. Curr. Gene Ther. 1, 149-162.
-
(2001)
Curr. Gene Ther.
, vol.1
, pp. 149-162
-
-
Breyer, B.1
Jiang, W.2
Cheng, H.3
Zhou, L.4
Paul, R.5
Feng, T.6
He, T.C.7
-
3
-
-
0034219436
-
Adeno-associated viral vectors as gene delivery vehicles
-
CARTER, P.J., and SAMULSKI, R.J. (2000). Adeno-associated viral vectors as gene delivery vehicles. Int. J. Mol. Med. 6, 17-27.
-
(2000)
Int. J. Mol. Med.
, vol.6
, pp. 17-27
-
-
Carter, P.J.1
Samulski, R.J.2
-
4
-
-
0036301577
-
Pancreatic organogenesis: Developmental mechanisms and implications for therapy
-
EDLUND, H. (2002). Pancreatic organogenesis: Developmental mechanisms and implications for therapy. Nat. Rev. Genet. 3, 524-532.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 524-532
-
-
Edlund, H.1
-
5
-
-
0036592086
-
A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo
-
EHRHARDT, A., and KAY, M.A. (2002). A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo. Blood 99, 3923-3930.
-
(2002)
Blood
, vol.99
, pp. 3923-3930
-
-
Ehrhardt, A.1
Kay, M.A.2
-
6
-
-
0035127574
-
Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors
-
FLOTTE, T., AGARWAL, A., WANG, J., SONG, S., FENJVES, E.S., INVERARDI, L., CHESNUT, K. AHONE, S., LOILER, S., WASSERFALL, C., KAPTURCZAK, M., ELLIS, T., NICK, H., and ATKINSON, M. (2001). Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors. Diabetes 50, 515-552.
-
(2001)
Diabetes
, vol.50
, pp. 515-552
-
-
Flotte, T.1
Agarwal, A.2
Wang, J.3
Song, S.4
Fenjves, E.S.5
Inverardi, L.6
Chesnut, K.7
Ahone, S.8
Loiler, S.9
Wasserfall, C.10
Kapturczak, M.11
Ellis, T.12
Nick, H.13
Atkinson, M.14
-
7
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
GAO, G., ALVIRA, M.R., WANG, L., CALCEDO, R., JOHNSTON, J., and WILSON, J.M. (2002). Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc. Natl. Acad. Sci. U.S.A. 99, 11854-11859.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 11854-11859
-
-
Gao, G.1
Alvira, M.R.2
Wang, L.3
Calcedo, R.4
Johnston, J.5
Wilson, J.M.6
-
8
-
-
1542369977
-
From virus evolution to vector revolution: Use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
-
GRIMM, D., and KAY, M.A. (2003a). From virus evolution to vector revolution: Use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr. Gene Ther. 3, 281-304.
-
(2003)
Curr. Gene Ther.
, vol.3
, pp. 281-304
-
-
Grimm, D.1
Kay, M.A.2
-
9
-
-
0038150506
-
Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
-
GRIMM, D., KAY, M.A., and KLEINSCHMIDT, J. (2003b). Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6. Mol. Ther. 7, 839-850.
-
(2003)
Mol. Ther.
, vol.7
, pp. 839-850
-
-
Grimm, D.1
Kay, M.A.2
Kleinschmidt, J.3
-
10
-
-
0035352703
-
Adeno-associated virus (AAV) as a vehicle for therapeutic gene delivery: Improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet transplantation for the reversal of type 1 diabetes
-
KAPTURCZAK, M.H., FLOTTE, T., and ATKINSON, M.A. (2001). Adeno-associated virus (AAV) as a vehicle for therapeutic gene delivery: Improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet transplantation for the reversal of type 1 diabetes. Curr. Mol. Med. 1, 245-258.
-
(2001)
Curr. Mol. Med.
, vol.1
, pp. 245-258
-
-
Kapturczak, M.H.1
Flotte, T.2
Atkinson, M.A.3
-
11
-
-
0027033259
-
Direct hepatic gene delivery in mice results in persistent expression of human alpha-1-antitrypsin in vivo
-
KAY, M.A., LI Q.T., LIU, T.J., LELAND, F., FINEGOLD, M., and WOO, S.L.C. (1992). Direct hepatic gene delivery in mice results in persistent expression of human alpha-1-antitrypsin in vivo. Hum. Gene Ther. 3, 641-647.
-
(1992)
Hum. Gene Ther.
, vol.3
, pp. 641-647
-
-
Kay, M.A.1
Li, Q.T.2
Liu, T.J.3
Leland, F.4
Finegold, M.5
Woo, S.L.C.6
-
12
-
-
0028274169
-
In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs
-
KAY, M.A., LANDEN, C.N., ROTHENBERG, S.R., TAYLOR, L.A., LELAND, F., WIEHLE, S., FANG, B., BELLINGER, D., FINEGOLD, M., THOMPSON, A.R., READ, M., BRINKHOUS, K.M., and WOO S.L.C. (1994). In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc. Natl. Acad. Sci. U.S.A. 91, 2353-2357.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 2353-2357
-
-
Kay, M.A.1
Landen, C.N.2
Rothenberg, S.R.3
Taylor, L.A.4
Leland, F.5
Wiehle, S.6
Fang, B.7
Bellinger, D.8
Finegold, M.9
Thompson, A.R.10
Read, M.11
Brinkhous, K.M.12
Woo, S.L.C.13
-
13
-
-
0018652555
-
Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens
-
LEDBETTER, J.A., and HERZENBERG, L.A. (1979). Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47, 63-90.
-
(1979)
Immunol. Rev.
, vol.47
, pp. 63-90
-
-
Ledbetter, J.A.1
Herzenberg, L.A.2
-
15
-
-
0030781362
-
Effect of adenoviral early genes and the host immune response system on in vivo pancreatic gene transfer in the mouse
-
MCCLANE, S.J., HAMILTON, T.E., DEMATTEO R.P., BURKE, C., and RAPER, S.E. (1997a). Effect of adenoviral early genes and the host immune response system on in vivo pancreatic gene transfer in the mouse. Pancreas 15, 236-245.
-
(1997)
Pancreas
, vol.15
, pp. 236-245
-
-
Mcclane, S.J.1
Hamilton, T.E.2
Dematteo, R.P.3
Burke, C.4
Raper, S.E.5
-
16
-
-
0030983596
-
Functional consequences of adenovirus-mediated murine pancreas gene transfer
-
MCCLANE, S.J., HAMILTON, T.E., BURKE, C.V., and RAPER, S.E. (1997b). Functional consequences of adenovirus-mediated murine pancreas gene transfer. Hum. Gene Ther. 8, 739-746.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 739-746
-
-
Mcclane, S.J.1
Hamilton, T.E.2
Burke, C.V.3
Raper, S.E.4
-
17
-
-
0033978147
-
AAV vectors: Is clinical success on the horizon?
-
MONAHAN, P.E., and SAMULSKI, R.J. (2000). AAV vectors: Is clinical success on the horizon? Gene Ther. 7, 24-30.
-
(2000)
Gene Ther.
, vol.7
, pp. 24-30
-
-
Monahan, P.E.1
Samulski, R.J.2
-
18
-
-
0037252019
-
Lipase and pancreatic amylase versus total amylase as biomarkers of pancreatitis: An analytical investigation
-
MORIDANI, M.Y., and BROMBERG, I.L. (2003). Lipase and pancreatic amylase versus total amylase as biomarkers of pancreatitis: An analytical investigation. Clin. Biochem. 36, 31-33.
-
(2003)
Clin. Biochem.
, vol.36
, pp. 31-33
-
-
Moridani, M.Y.1
Bromberg, I.L.2
-
19
-
-
0034033447
-
Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors
-
NAKAI, H., STORM, T.A., and KAY, M.A. (2000). Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors. Nat. Biotechnol. 18, 527-532.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 527-532
-
-
Nakai, H.1
Storm, T.A.2
Kay, M.A.3
-
20
-
-
0033986340
-
Efficient lentiviral transduction of liver requires cell cycling in vivo
-
PARK, F., OHASHI, K., CHIU, W., and KAY, M.A. (2000). Efficient lentiviral transduction of liver requires cell cycling in vivo. Nat. Genet. 24, 49-52.
-
(2000)
Nat. Genet.
, vol.24
, pp. 49-52
-
-
Park, F.1
Ohashi, K.2
Chiu, W.3
Kay, M.A.4
-
21
-
-
0033780918
-
Adeno-associated virus vector mediated gene transfer to pancreatic beta cells
-
PRASAD, K.M., YANG, Z., BLEICH, D., and NADLER, J.L. (2000). Adeno-associated virus vector mediated gene transfer to pancreatic beta cells. Gene Ther. 7, 1553-1561.
-
(2000)
Gene Ther.
, vol.7
, pp. 1553-1561
-
-
Prasad, K.M.1
Yang, Z.2
Bleich, D.3
Nadler, J.L.4
-
22
-
-
0034220667
-
Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors
-
PRUDHOMME, G.J. (2000). Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors. J. Gene Med. 2, 222-232.
-
(2000)
J. Gene Med.
, vol.2
, pp. 222-232
-
-
Prudhomme, G.J.1
-
23
-
-
0029933105
-
Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas
-
RAPER, S.E., and DEMATTEO, R.P. (1996). Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas. Pancreas 12, 401-410.
-
(1996)
Pancreas
, vol.12
, pp. 401-410
-
-
Raper, S.E.1
Dematteo, R.P.2
-
24
-
-
0031984786
-
Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2
-
RUTLEDGE, E.A., HALBERT, C.L., and RUSSELL, D.W. (1998). Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J. Virol. 72, 309-319.
-
(1998)
J. Virol.
, vol.72
, pp. 309-319
-
-
Rutledge, E.A.1
Halbert, C.L.2
Russell, D.W.3
-
25
-
-
0033122032
-
Adeno-associated virus-mediated gene delivery
-
SNYDER, R.O. (1999). Adeno-associated virus-mediated gene delivery. J. Gene Med. 1, 166-175.
-
(1999)
J. Gene Med.
, vol.1
, pp. 166-175
-
-
Snyder, R.O.1
-
26
-
-
0030997346
-
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
-
SNYDER, R.O., MIAO, C.H., PATIJN, G.J., PRATT, S.K., DANOS, O., GOWN, A.M., WINTHER, B., MEUSE, L., COHEN, L.K., THOMPSON, A.R., and KAY, M.A. (1997). Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat. Genet. 16, 270-276.
-
(1997)
Nat. Genet.
, vol.16
, pp. 270-276
-
-
Snyder, R.O.1
Miao, C.H.2
Patijn, G.J.3
Pratt, S.K.4
Danos, O.5
Gown, A.M.6
Winther, B.7
Meuse, L.8
Cohen, L.K.9
Thompson, A.R.10
Kay, M.A.11
-
27
-
-
0037228848
-
Adeno-associated virus vectors for therapeutic gene transfer
-
STILWELL, J.L., and SAMULSKI, R.J. (2003). Adeno-associated virus vectors for therapeutic gene transfer. Biotechniques 34, 148-150.
-
(2003)
Biotechniques
, vol.34
, pp. 148-150
-
-
Stilwell, J.L.1
Samulski, R.J.2
-
28
-
-
1542347741
-
Rapid uncoating of vector genomes is the key to efficient liver transduction with AAV pseudotyped vectors
-
in press
-
THOMAS, C.E., STORM, T.A., HUANG, Z., and KAY, M.A. (2004). Rapid uncoating of vector genomes is the key to efficient liver transduction with AAV pseudotyped vectors. J. Virol. (in press).
-
(2004)
J. Virol.
-
-
Thomas, C.E.1
Storm, T.A.2
Huang, Z.3
Kay, M.A.4
-
29
-
-
0036789403
-
Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo
-
YANT, S.R., EHRHARDT, A., MIKKELSEN, J.G., MEUSE, L., PHAM, T., KAY, M.A. (2002). Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo. Nat. Biotechnol. 20, 999-1005.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 999-1005
-
-
Yant, S.R.1
Ehrhardt, A.2
Mikkelsen, J.G.3
Meuse, L.4
Pham, T.5
Kay, M.A.6
-
30
-
-
0036227449
-
Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors
-
ZAISS, A.K., LIU, Q., BOWEN, G.P., WONG, N.C., BARTLETT, J.S., and MURUVE, D.A. (2002). Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors. J. Virol. 76, 4580-4590.
-
(2002)
J. Virol.
, vol.76
, pp. 4580-4590
-
-
Zaiss, A.K.1
Liu, Q.2
Bowen, G.P.3
Wong, N.C.4
Bartlett, J.S.5
Muruve, D.A.6
|