Epac signaling pathway involves STEF, a guanine nucleotide exchange factor for Rac, to regulate APP processing

FEBS Letters

Volumn 581, Issue 30, 2007, Pages 5814-5818

  Zaldua, Natalia ^a   Gastineau, Monique ^b,c   Hoshino, Mikio ^d,e   Lezoualc'h, Frank ^b,c   Zugaza, José L ^a  

^a CIC BIOGUNE   (Spain)

^b Universite Paris Sud   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d KYOTO UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Alzheimer's disease; Amyloid; cAMP; Guanine nucleotide exchange factor; Serotonin; Small G protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CYCLIC AMP; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN EPAC; PROTEIN STEF; RAC PROTEIN; RAP1 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECRETION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN; ANIMALS; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; CRICETULUS; ENZYME ACTIVATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RAC GTP-BINDING PROTEINS; RAP1 GTP-BINDING PROTEINS; RECEPTORS, SEROTONIN, 5-HT4; SIGNAL TRANSDUCTION; SOLUBILITY;

EID: 37049014456     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.11.053     Document Type: Article

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