메뉴 건너뛰기




Volumn 297, Issue 4, 2009, Pages

Epac increases melanoma cell migration by a heparan sulfate-related mechanism

Author keywords

Metastasis; N deacetylase N sulfotransferase 1; Phosphoinositol 3 kinase

Indexed keywords

FLOTILLIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HEPARAN SULFATE; MEMBRANE PROTEIN; N SULFOTRANSFERASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN EPAC; PROTEIN EPAC1; PROTEIN EPAC2; SMALL INTERFERING RNA; SYNDECAN 2; TUBULIN; UNCLASSIFIED DRUG;

EID: 70349898597     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00129.2009     Document Type: Article
Times cited : (39)

References (49)
  • 1
    • 67650436092 scopus 로고    scopus 로고
    • Clustering of Syndecan-4 and integrin β1 by iaminin α3 chain-derived peptide promotes keratinocyte migration
    • Araki E, Momota Y, Togo T, Tanioka M, Hozumi K, Nomizu M, Miyachi Y, Utani A. Clustering of Syndecan-4 and integrin β1 by iaminin α3 chain-derived peptide promotes keratinocyte migration. Mol Biol Cell 20: 3012-3024, 2009.
    • (2009) Mol Biol Cell , vol.20 , pp. 3012-3024
    • Araki, E.1    Momota, Y.2    Togo, T.3    Tanioka, M.4    Hozumi, K.5    Nomizu, M.6    Miyachi, Y.7    Utani, A.8
  • 2
    • 39749187284 scopus 로고    scopus 로고
    • Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): Multifunctional proteins in cancer
    • DOI 10.1038/nrc2345, PII NRC2345
    • Bellahcene A, Castronovo V, Ogbureke KU, Fisher LW, Fedarko NS. Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer. Nat Rev Cancer 8: 212-226, 2008. (Pubitemid 351301854)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.3 , pp. 212-226
    • Bellahcene, A.1    Castronovo, V.2    Ogbureke, K.U.E.3    Fisher, L.W.4    Fedarko, N.S.5
  • 3
    • 0030800343 scopus 로고    scopus 로고
    • Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein: Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein
    • DOI 10.1074/jbc.272.33.20435
    • Benoist F and Grand-Perret T. Cotranslational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein. J Biol Chem 272: 20435-20442, 1997. (Pubitemid 27355596)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.33 , pp. 20435-20442
    • Benoist, F.1    Grand-Perret, T.2
  • 5
    • 32844463799 scopus 로고    scopus 로고
    • The current epidemiology of cutaneous malignant melanoma
    • Berwick M, Wiggins C. The current epidemiology of cutaneous malignant melanoma. Front Biosci 11: 1244-1254, 2006. (Pubitemid 43253416)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.2 P.1199-1590 , pp. 1244-1254
    • Berwick, M.1    Wiggins, C.2
  • 6
    • 33751241720 scopus 로고    scopus 로고
    • Epac proteins: Multi-purpose cAMP targets
    • Bos JL. Epac proteins: multi-purpose cAMP targets. Trends Biochem Sci 31: 680-686, 2006.
    • (2006) Trends Biochem Sci , vol.31 , pp. 680-686
    • Bos, J.L.1
  • 7
    • 24344439701 scopus 로고    scopus 로고
    • Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: Implications for cross talk between insulin and adrenaline
    • DOI 10.1016/j.cellsig.2005.03.011, PII S0898656805000641
    • Brennesvik EO, Ktori C, Ruzzin J, Jebens E, Shepherd PR, Jensen J. Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline. Cell Signal 17: 1551-1559, 2005. (Pubitemid 41253994)
    • (2005) Cellular Signalling , vol.17 , Issue.12 , pp. 1551-1559
    • Brennesvik, E.O.1    Ktori, C.2    Ruzzin, J.3    Jebens, E.4    Shepherd, P.R.5    Jensen, J.6
  • 8
    • 0036343395 scopus 로고    scopus 로고
    • Immunoreactivity to cell surface syndecans in cytoplasm and nucleus: Tubulin-dependent rearrangements
    • DOI 10.1006/excr.2002.5477
    • Brockstedt U, Dobra K, Nurminen M, Hjerpe A. Immunoreactivity to cell surface syndecans in cytoplasm and nucleus: tubulin-dependent rearrangements. Exp Cell Res 274: 235-245, 2002. (Pubitemid 34946965)
    • (2002) Experimental Cell Research , vol.274 , Issue.2 , pp. 235-245
    • Brockstedt, U.1    Dobra, K.2    Nurminen, M.3    Hjerpe, A.4
  • 9
    • 0025915427 scopus 로고
    • Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis
    • Byers HR, Etoh T, Doherty JR, Sober AJ, Mihm MC Jr. Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis. Am J Pathol 139: 423-435, 1991.
    • (1991) Am J Pathol , vol.139 , pp. 423-435
    • Byers, H.R.1    Etoh, T.2    Doherty, J.R.3    Sober, A.J.4    Mihm Jr., M.C.5
  • 11
    • 0030031898 scopus 로고    scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
    • Claffey KP, Brown LF, del Aguila LF, Tognazzi K, Yeo KT, Manseau EJ, Dvorak HF. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res 56: 172-181, 1996. (Pubitemid 26010397)
    • (1996) Cancer Research , vol.56 , Issue.1 , pp. 172-181
    • Claffey, K.P.1    Brown, L.F.2    Del Aguila, L.F.3    Tognazzi, K.4    Yeo, K.-T.5    Manseau, E.J.6    Dvorak, H.F.7
  • 13
    • 0033535040 scopus 로고    scopus 로고
    • Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons
    • DOI 10.1083/jcb.144.3.575
    • Ethell IM, Yamaguchi Y. Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons. J Cell Biol 144: 575-586, 1999. (Pubitemid 29234535)
    • (1999) Journal of Cell Biology , vol.144 , Issue.3 , pp. 575-586
    • Ethell, I.M.1    Yamaguchi, Y.2
  • 14
    • 24144477955 scopus 로고    scopus 로고
    • Decreasing the metastatic potential in cancers - Targeting the heparan sulfate proteoglycans
    • DOI 10.2174/1389450054863662
    • Fjeldstad K, Kolset SO. Decreasing the metastatic potential in cancers-targeting the heparan sulfate proteoglycans. Curr Drug Targets 6: 665-682, 2005. (Pubitemid 41236550)
    • (2005) Current Drug Targets , vol.6 , Issue.6 , pp. 665-682
    • Fjeldstad, K.1    Kolset, S.O.2
  • 15
    • 0034433063 scopus 로고    scopus 로고
    • Axonal transport of tubulin and actin
    • Galbraith JA, Gallant PE. Axonal transport of tubulin and actin. J Neurocytol 29: 889-911, 2000.
    • (2000) J Neurocytol , vol.29 , pp. 889-911
    • Galbraith, J.A.1    Gallant, P.E.2
  • 16
    • 33748054771 scopus 로고    scopus 로고
    • Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: Two processes important to melanoma tumorigenesis and metastasis
    • DOI 10.1158/0008-5472.CAN-06-0254
    • Gao L, Feng Y, Bowers R, Becker-Hapak M, Gardner J, Council L, Linette G, Zhao H, Cornelius LA. Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis. Cancer Res 66: 7880-7888, 2006. (Pubitemid 44299150)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 7880-7888
    • Gao, L.1    Feng, Y.2    Bowers, R.3    Becker-Hapak, M.4    Gardner, J.5    Council, L.6    Linette, G.7    Zhao, H.8    Cornelius, L.A.9
  • 19
    • 0034959158 scopus 로고    scopus 로고
    • Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions
    • Iozzo RV. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions. J Clin Invest 108: 165-167, 2001.
    • (2001) J Clin Invest , vol.108 , pp. 165-167
    • Iozzo, R.V.1
  • 22
    • 11244334132 scopus 로고    scopus 로고
    • 2
    • DOI 10.1074/jbc.M409816200
    • Jing H, Yen JH, Ganea D. A novel signaling pathway mediates the inhibition of CCL3/4 expression by prostaglandin E2. J Biol Chem 279: 55176-55186, 2004. (Pubitemid 40066512)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.53 , pp. 55176-55186
    • Jing, H.1    Yen, J.-H.2    Ganea, D.3
  • 24
    • 3042857264 scopus 로고    scopus 로고
    • A model for non-viral gene delivery: Through syndecan adhesion molecules and powered by actin
    • DOI 10.1002/jgm.558
    • Kopatz I, Remy JS, Behr JP. A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin. J Gene Med 6: 769-776, 2004. (Pubitemid 40228093)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.7 , pp. 769-776
    • Kopatz, I.1    Remy, J.-S.2    Behr, J.-P.3
  • 25
    • 0033601228 scopus 로고    scopus 로고
    • Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts
    • DOI 10.1074/jbc.274.52.36921
    • Krauss K, Altevogt P. Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts. J Biol Chem 274: 36921-36927, 1999. (Pubitemid 30016759)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.52 , pp. 36921-36927
    • Krauss, K.1    Altevogt, P.2
  • 26
    • 0036500126 scopus 로고    scopus 로고
    • The involvement of lipid rafts in the regulation of integrin function
    • Leitinger B, Hogg N. The involvement of lipid rafts in the regulation of integrin function. J Cell Sci 115: 963-972, 2002. (Pubitemid 34257381)
    • (2002) Journal of Cell Science , vol.115 , Issue.5 , pp. 963-972
    • Leitinger, B.1    Hogg, N.2
  • 27
    • 0022460623 scopus 로고
    • CAMP metabolism in B16 melanoma clones during the formation of experimental and spontaneous metastases
    • Lester BR, Greig RG, Buscarino C, Sheppard JR, Corwin SP, Poste G. cAMP metabolism in B16 melanoma clones during the formation of experimental and spontaneous metastases. Int J Cancer 38: 405-411, 1986. (Pubitemid 16022324)
    • (1986) International Journal of Cancer , vol.38 , Issue.3 , pp. 405-411
    • Lester, B.R.1    Greig, R.G.2    Buscarino, C.3
  • 29
    • 27644580732 scopus 로고    scopus 로고
    • Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton
    • DOI 10.1039/b511267b
    • Mei FC, Cheng X. Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton. Mol BioSys 1: 325-331, 2005. (Pubitemid 41579325)
    • (2005) Molecular BioSystems , vol.1 , Issue.4 , pp. 325-331
    • Mei, F.C.1    Cheng, X.2
  • 30
    • 33645162400 scopus 로고    scopus 로고
    • Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- And F-actin-rich domains
    • Millan J, Hewlett L, Glyn M, Toomre D, Clark P, Ridley AJ. Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains. Nat Cell Biol 8: 113-123, 2006.
    • (2006) Nat Cell Biol , vol.8 , pp. 113-123
    • Millan, J.1    Hewlett, L.2    Glyn, M.3    Toomre, D.4    Clark, P.5    Ridley, A.J.6
  • 31
    • 33644688682 scopus 로고    scopus 로고
    • Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: Effects of silencing CREB gene expression on Akt activation
    • Misra UK, Pizzo SV. Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. J Biol Chem 280: 38276-38289, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 38276-38289
    • Misra, U.K.1    Pizzo, S.V.2
  • 32
    • 33947114373 scopus 로고    scopus 로고
    • Asymmetric localization of calpain 2 during neutrophil chemotaxis
    • DOI 10.1091/mbc.E06-09-0876
    • Nuzzi PA, Senetar MA, Huttenlocher A. Asymmetric localization of calpain 2 during neutrophil chemotaxis. Mol Biol Cell 18: 795-805, 2007. (Pubitemid 46399486)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.3 , pp. 795-805
    • Nuzzi, P.A.1    Senetar, M.A.2    Huttenlocher, A.3
  • 33
    • 0024505157 scopus 로고
    • Different growth responses to agents which elevate cAMP in human melanoma cell lines of high and low experimental metastatic capacity
    • Ormerod EJ, Hart IR. Different growth responses to agents which elevate cAMP in human melanoma cell lines of high and low experimental metastatic capacity. Clin Exp Metast 7: 85-95, 1989.
    • (1989) Clin Exp Metast , vol.7 , pp. 85-95
    • Ormerod, E.J.1    Hart, I.R.2
  • 35
    • 0038521285 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 signaling in brain endothelial cells: Specific role for glypican-1 in glioma angiogenesis
    • DOI 10.1074/jbc.M211259200
    • Qiao D, Meyer K, Mundhenke C, Drew SA, Friedl A. Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 signaling in brain endothelial cells. Specific role for glypican-1 in glioma angiogenesis. J Biol Chem 278: 16045-16053, 2003. (Pubitemid 36799725)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.18 , pp. 16045-16053
    • Qiao, D.1    Meyer, K.2    Mundhenke, C.3    Drew, S.A.4    Friedl, A.5
  • 36
    • 0030664773 scopus 로고    scopus 로고
    • Hydroxyl radicals depolymerize glomerular heparan sulfate in vitro and in experimental nephrotic syndrome
    • Raats CJI, Bakker MAH, van den Born J, Berden JHM. Hydroxyl radicals depolymerize glomerular heparan sulfate in vitro and in experimental nephrotic syndrome. J Biol Chem 272: 26734-26741, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 26734-26741
    • Raats, C.J.I.1    Bakker, M.A.H.2    Van Den Born, J.3    Berden, J.H.M.4
  • 37
    • 1542394042 scopus 로고    scopus 로고
    • Measurement of the motility of endothelial cells in confluent monolayers
    • DOI 10.1038/sj.mn.7800184
    • Rickard A, Portell C, Siegal J, Goeckeler Z, Lagunoff D. Measurement of the motility of endothelial cells in confluent monolayers. Microcirculation 10: 193-203, 2003. (Pubitemid 39004247)
    • (2003) Microcirculation , vol.10 , Issue.2 , pp. 193-203
    • Rickard, A.1    Portell, C.2    Siegal, J.3    Goeckeller, Z.4    Lagunoff, D.5
  • 38
    • 0027099848 scopus 로고
    • Contact stimulation of cell migration
    • Thomas LA, Yamada KM. Contact stimulation of cell migration. J Cell Sci 103: 1211-1214, 1992.
    • (1992) J Cell Sci , vol.103 , pp. 1211-1214
    • Thomas, L.A.1    Yamada, K.M.2
  • 39
    • 33745401241 scopus 로고    scopus 로고
    • Syndecan-4 clustering induces cell migration in a PDZ-dependent manner
    • DOI 10.1161/01.RES.0000225283.71490.5a, PII 0000301220060609000010
    • Tkachenko E, Elfenbein A, Tirziu D, Simons M. Syndecan-4 clustering induces cell migration in a PDZ-dependent manner. Circ Res 98: 1398-1404, 2006. (Pubitemid 43948064)
    • (2006) Circulation Research , vol.98 , Issue.11 , pp. 1398-1404
    • Tkachenko, E.1    Elfenbein, A.2    Tirziu, D.3    Simons, M.4
  • 40
    • 0037205432 scopus 로고    scopus 로고
    • Clustering induces redistribution of syndecan-4 core protein into raft membrane domains
    • DOI 10.1074/jbc.M200841200
    • Tkachenko E, Simons M. Clustering induces redistribution of syndecan-4 core protein into raft membrane domains. J Biol Chem 277: 19946-19951, 2002. (Pubitemid 34967516)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.22 , pp. 19946-19951
    • Tkachenko, E.1    Simons, M.2
  • 42
    • 11144226727 scopus 로고    scopus 로고
    • The Caveolin genes: From cell biology to medicine
    • Williams TM, Lisanti MP. The Caveolin genes: from cell biology to medicine. Ann Med 36: 584-595, 2004.
    • (2004) Ann Med , vol.36 , pp. 584-595
    • Williams, T.M.1    Lisanti, M.P.2
  • 45
    • 0037359709 scopus 로고    scopus 로고
    • Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans
    • DOI 10.1016/S0945-053X(03)00010-6, PII S0945053X03000106
    • Yoneda A, Couchman JR. Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans. Matrix Biol 22: 25-33, 2003. (Pubitemid 36444504)
    • (2003) Matrix Biology , vol.22 , Issue.1 , pp. 25-33
    • Yoneda, A.1    Couchman, J.R.2
  • 46
    • 0025606452 scopus 로고
    • Relationship between secreted urokinase plasminogen activator activity and metastatic potential in murine B16 cells transfected with human urokinase sense and antisense genes
    • Yu HR, Schultz RM. Relationship between secreted urokinase plasminogen activator activity and metastatic potential in murine B16 cells transfected with human urokinase sense and antisense genes. Cancer Res 50: 7623-7633, 1990.
    • (1990) Cancer Res , vol.50 , pp. 7623-7633
    • Yu, H.R.1    Schultz, R.M.2
  • 47
    • 0032561364 scopus 로고    scopus 로고
    • The retinoic acid and cAMP-dependent up-regulation of 3-O- Sulfotransferase-1 leads to a dramatic augmentation of anticoagulantly active heparan sulfate biosynthesis in F9 embryonal carcinoma cells
    • DOI 10.1074/jbc.273.43.27998
    • Zhang L, Schwartz JJ, Miller J, Liu J, Fritze LMS, Shworak NW, Rosenberg RD. The retinoic acid and cAMP-dependent up-regulation of 3-O-sulfotransferase-1 leads to a dramatic augmentation of anticoagulantly active heparan sulfate biosynthesis in F9 embryonal carcinoma Cells. J Biol Chem 273: 27998-28003, 1998. (Pubitemid 28496091)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.43 , pp. 27998-28003
    • Zhang, L.1    Schwartz, J.J.2    Miller, J.3    Liu, J.4    Fritze, L.M.S.5    Shworak, N.W.6    Rosenberg, R.D.7
  • 48
    • 17644415297 scopus 로고    scopus 로고
    • Snider Cell biology WD. GSK-3beta and microtubule assembly in axons
    • Zhou FQ, Snider Cell biology WD. GSK-3beta and microtubule assembly in axons. Science 308: 211-214, 2005.
    • (2005) Science , vol.308 , pp. 211-214
    • Zhou, F.Q.1
  • 49
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation
    • DOI 10.1016/S0960-9822(01)00002-1
    • Zumbrunn J, Kinoshita K, Hyman AA, Nathke IS. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr Biol 11: 44-49, 2001. (Pubitemid 32062715)
    • (2001) Current Biology , vol.11 , Issue.1 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.