Epac-selective cAMP analog 8-pCPT-2′-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic β-cells

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 8279-8285

  Kang, Guoxin ^a   Joseph, Jamie W ^b   Chepurny, Oleg G ^a   Monaco, Marie ^a   Wheeler, Michael B ^b   Bos, Johannes L ^c   Schwede, Frank ^d   Genieser, Hans G ^d   Holz, George G ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d BIOLOG Life Science Institute   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CALCIUM; CELLS; HORMONES;

STIMULATORY EFFECTS;

COENZYMES;

8 (4 CHLOROPHENYLTHIO) 2' O METHYLADENOSINE 3',5' CYCLIC MONOPHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCAGON LIKE PEPTIDE 1; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAP PROTEIN; UNCLASSIFIED DRUG; 8 (4 CHLORO PHENYLTHIO) 2' O METHYLADENOSINE 3' 5' CYCLIC MONOPHOSPHATE; 8-(4-CHLORO-PHENYLTHIO)-2'-O-METHYLADENOSINE-3'-5'-CYCLIC MONOPHOSPHATE; BACTERIAL PROTEIN; CALCIUM; DRUG DERIVATIVE; PHOTOPROTEIN; RAPGEF3 PROTEIN, HUMAN; YELLOW FLUORESCENT PROTEIN, BACTERIA;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; EFFECTOR CELL; EXOCYTOSIS; HUMAN; HUMAN CELL; INSULIN LIKE ACTIVITY; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ELECTROCHEMISTRY; IMMUNOHISTOCHEMISTRY; METABOLISM; PANCREAS ISLET;

BACTERIAL PROTEINS; CALCIUM; CELLS, CULTURED; CYCLIC AMP; ELECTROCHEMISTRY; EXOCYTOSIS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; LUMINESCENT PROTEINS;

EID: 0037424363     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211682200     Document Type: Article

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