메뉴 건너뛰기




Volumn 26, Issue 17, 2006, Pages 6333-6346

Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE ACTIVATOR; ANTIPORTER; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN GP 130; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; PROTEIN EPAC; PROTEIN INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAP1 PROTEIN; SMALL INTERFERING RNA; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG;

EID: 33747749486     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00207-06     Document Type: Article
Times cited : (121)

References (59)
  • 1
    • 25144476013 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of the endothelium
    • Aird, W. C. 2005. Spatial and temporal dynamics of the endothelium. J. Thromb. Haemost. 3:1392-1406.
    • (2005) J. Thromb. Haemost. , vol.3 , pp. 1392-1406
    • Aird, W.C.1
  • 2
    • 2542478996 scopus 로고    scopus 로고
    • The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
    • Alexander, W. S., and D. J. Hilton. 2004. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu. Rev. Immunol. 22:503-529.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 503-529
    • Alexander, W.S.1    Hilton, D.J.2
  • 3
    • 0035861559 scopus 로고    scopus 로고
    • Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor a, and oncostatin M receptor-β by distinct mechanisms
    • Blanchard, F., W. Yanping, E. Kinzie, L. Duplomb, A. Godard, and H. Baumann. 2001. Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor a, and oncostatin M receptor-β by distinct mechanisms. J. Biol. Chem. 276:47038-47045.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47038-47045
    • Blanchard, F.1    Yanping, W.2    Kinzie, E.3    Duplomb, L.4    Godard, A.5    Baumann, H.6
  • 4
    • 0031919107 scopus 로고    scopus 로고
    • Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4
    • Blease, K., A. Burke-Gaffney, and P. G. Hellewell. 1998. Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4. Br. J. Pharmacol. 124:229-237.
    • (1998) Br. J. Pharmacol. , vol.124 , pp. 229-237
    • Blease, K.1    Burke-Gaffney, A.2    Hellewell, P.G.3
  • 5
    • 0041836339 scopus 로고    scopus 로고
    • Epac: A new cAMP target and new avenues in cAMP research
    • Bos, J. L. 2003. Epac: a new cAMP target and new avenues in cAMP research. Nat. Rev. Mol. Cell Biol. 4:733-738.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 733-738
    • Bos, J.L.1
  • 6
    • 14544272401 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: Advances in the development of specific phosphodiesterase inhibitors
    • Castro, A., M. J. Jerez, C. Gil, and A. Martinez. 2005. Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors. Med. Res. Rev. 25:229-244.
    • (2005) Med. Res. Rev. , vol.25 , pp. 229-244
    • Castro, A.1    Jerez, M.J.2    Gil, C.3    Martinez, A.4
  • 9
    • 14944377651 scopus 로고    scopus 로고
    • Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase
    • Cullere, X., S. K. Shaw, L. Andersson, J. Hirahashi, F. W. Luscinskas, and T. N. Mayadas. 2005. Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. Blood 105:1950-1955.
    • (2005) Blood , vol.105 , pp. 1950-1955
    • Cullere, X.1    Shaw, S.K.2    Andersson, L.3    Hirahashi, J.4    Luscinskas, F.W.5    Mayadas, T.N.6
  • 11
    • 0037195421 scopus 로고    scopus 로고
    • 3-dependent endothelial cell adhesion, Rac-activation, and spreading through cAMP/PKA-dependent signaling
    • 3-dependent endothelial cell adhesion, Rac-activation, and spreading through cAMP/PKA-dependent signaling. J. Biol. Chem. 277:45838-45846.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45838-45846
    • Dormond, O.1    Bezzi, M.2    Mariotti, A.3    Ruegg, C.4
  • 15
    • 11144305139 scopus 로고    scopus 로고
    • Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway
    • Fukuhara, S., A. Sakurai, H. Sano, A. Yamagishi, S. Somekawa, N. Takakura, Y. Saito, K. Kangawa, and N. Mochizuki. 2005. Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol. Cell. Biol. 25:136-146.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 136-146
    • Fukuhara, S.1    Sakurai, A.2    Sano, H.3    Yamagishi, A.4    Somekawa, S.5    Takakura, N.6    Saito, Y.7    Kangawa, K.8    Mochizuki, N.9
  • 16
    • 0036096798 scopus 로고    scopus 로고
    • Interleukin-10 and cAMP-elevating agents cooperate to induce suppressor of cytokine signaling-3 via a protein kinase A-independent signal
    • Gasperini, S., L. Crepaldi, F. Calzetti, L. Gatto, C. Berlato, F. Bazzoni, A. Yoshimura, and M. A. Cassatella. 2002. Interleukin-10 and cAMP-elevating agents cooperate to induce suppressor of cytokine signaling-3 via a protein kinase A-independent signal. Eur. Cytokine Netw. 13:47-53.
    • (2002) Eur. Cytokine Netw. , vol.13 , pp. 47-53
    • Gasperini, S.1    Crepaldi, L.2    Calzetti, F.3    Gatto, L.4    Berlato, C.5    Bazzoni, F.6    Yoshimura, A.7    Cassatella, M.A.8
  • 17
    • 14844320785 scopus 로고    scopus 로고
    • MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion
    • Gupta, M., and S. J. Yarwood. 2005. MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion. J. Biol. Chem. 280:8109-8116.
    • (2005) J. Biol. Chem. , vol.280 , pp. 8109-8116
    • Gupta, M.1    Yarwood, S.J.2
  • 20
    • 0347990624 scopus 로고    scopus 로고
    • Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic β-cell
    • Holz, G. G. 2004. Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic β-cell. Diabetes 53:5-13.
    • (2004) Diabetes , vol.53 , pp. 5-13
    • Holz, G.G.1
  • 21
    • 0038728629 scopus 로고    scopus 로고
    • Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling
    • Insel, P. A., and R. S. Ostrom. 2003. Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling. Cell. Mol. Neurobiol. 23:305-314.
    • (2003) Cell. Mol. Neurobiol. , vol.23 , pp. 305-314
    • Insel, P.A.1    Ostrom, R.S.2
  • 22
    • 9744236585 scopus 로고    scopus 로고
    • Interleukin-6 induced basic fibroblast growth factor-dependent angiogenesis in basal cell carcinoma cell line via JAK/STAT3 and PI3-kinase/Akt pathways
    • Jee, S. H., C. Y. Chu, H. C. Chiu, Y. L. Huang, W. L. Tsai, Y. H. Liao, and M. L. Kuo. 2004. Interleukin-6 induced basic fibroblast growth factor-dependent angiogenesis in basal cell carcinoma cell line via JAK/STAT3 and PI3-kinase/Akt pathways. J. Investig. Dermatol. 123:1169-1175.
    • (2004) J. Investig. Dermatol. , vol.123 , pp. 1169-1175
    • Jee, S.H.1    Chu, C.Y.2    Chiu, H.C.3    Huang, Y.L.4    Tsai, W.L.5    Liao, Y.H.6    Kuo, M.L.7
  • 26
    • 24144444059 scopus 로고    scopus 로고
    • Epac1 regulates integrity of endothelial cell junctions through VE-cadherin
    • Kooistra, M. R., M. Corada, E. Dejana, and J. L. Bos. 2005. Epac1 regulates integrity of endothelial cell junctions through VE-cadherin. FEBS Lett. 579:4966-4972.
    • (2005) FEBS Lett. , vol.579 , pp. 4966-4972
    • Kooistra, M.R.1    Corada, M.2    Dejana, E.3    Bos, J.L.4
  • 27
    • 0346121599 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and immunity
    • Kubo, M., T. Hanada, and A. Yoshimura. 2003. Suppressors of cytokine signaling and immunity. Nat. Immunol. 4:1169-1176.
    • (2003) Nat. Immunol. , vol.4 , pp. 1169-1176
    • Kubo, M.1    Hanada, T.2    Yoshimura, A.3
  • 28
    • 0035378665 scopus 로고    scopus 로고
    • Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway
    • Madamanchi, N. R., S. Li, C. Patterson, and M. S. Runge. 2001. Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway. J. Biol. Chem. 276:18915-18924.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18915-18924
    • Madamanchi, N.R.1    Li, S.2    Patterson, C.3    Runge, M.S.4
  • 29
    • 0041589198 scopus 로고    scopus 로고
    • Desensitization of signaling by oncostatin M in human vascular cells involves cytoplasmic Tyr residue 759 in gp130 but is not mediated by either Src homology 2 domain-containing tyrosine phosphatase 2 or suppressor of cytokine signaling 3
    • Mahboubi, K., N. C. Kirkiles-Smith, J. Karras, and J. S. Pober. 2002. Desensitization of signaling by oncostatin M in human vascular cells involves cytoplasmic Tyr residue 759 in gp130 but is not mediated by either Src homology 2 domain-containing tyrosine phosphatase 2 or suppressor of cytokine signaling 3. J. Biol. Chem. 278:25014-25023.
    • (2002) J. Biol. Chem. , vol.278 , pp. 25014-25023
    • Mahboubi, K.1    Kirkiles-Smith, N.C.2    Karras, J.3    Pober, J.S.4
  • 30
    • 0035884847 scopus 로고    scopus 로고
    • The IL-6-soluble IL-6Rα autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: An experimental model involving thrombin
    • Marin, V., F. A. Montera-Julian, S. Gres, V. Boulay, P. Bongrand, C. Farnarier, and G. Kaplanski. 2001. The IL-6-soluble IL-6Rα autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: an experimental model involving thrombin. J. Immunol. 167:3435-3442.
    • (2001) J. Immunol. , vol.167 , pp. 3435-3442
    • Marin, V.1    Montera-Julian, F.A.2    Gres, S.3    Boulay, V.4    Bongrand, P.5    Farnarier, C.6    Kaplanski, G.7
  • 33
    • 0026800892 scopus 로고
    • The cloning of a family of genes that encode the melanocortin receptors
    • Mountjoy, K. G., L. S. Robbins, M. T. Mortrud, and R. D. Cone. 1992. The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248-1251.
    • (1992) Science , vol.257 , pp. 1248-1251
    • Mountjoy, K.G.1    Robbins, L.S.2    Mortrud, M.T.3    Cone, R.D.4
  • 35
    • 0034532895 scopus 로고    scopus 로고
    • Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: Phosphorylation and activation by cAMP-dependent protein kinase
    • Rocchi, S., I. Gaillard, E. van Obberghen, E. M. Chambaz, and I. Vilgrain. 2000. Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinase. Biochem. J. 352:483-490.
    • (2000) Biochem. J. , vol.352 , pp. 483-490
    • Rocchi, S.1    Gaillard, I.2    Van Obberghen, E.3    Chambaz, E.M.4    Vilgrain, I.5
  • 36
    • 0041529514 scopus 로고    scopus 로고
    • SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation
    • Rogers, R. S., C. M. Horvath, and M. J. Matunis. 2003. SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation. J. Biol. Chem. 278:30091-30097.
    • (2003) J. Biol. Chem. , vol.278 , pp. 30091-30097
    • Rogers, R.S.1    Horvath, C.M.2    Matunis, M.J.3
  • 38
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • Rui, L., M. Yuan, D. Frantz, S. Shoelson, and M. F. White. 2002. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J. Biol. Chem. 277:42394-42398.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3    Shoelson, S.4    White, M.F.5
  • 40
    • 0037462645 scopus 로고    scopus 로고
    • The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6
    • Sasaki, A., K. Inagaki-Ohara, T. Yoshida, A. Yamanaka, M. Sasaki, H. Yasukawa, A. E. Koromilas, and A. Yoshimura. 2003. The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6. J. Biol. Chem. 278:2432-2436.
    • (2003) J. Biol. Chem. , vol.278 , pp. 2432-2436
    • Sasaki, A.1    Inagaki-Ohara, K.2    Yoshida, T.3    Yamanaka, A.4    Sasaki, M.5    Yasukawa, H.6    Koromilas, A.E.7    Yoshimura, A.8
  • 41
    • 0032803530 scopus 로고    scopus 로고
    • Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
    • Sasaki, A., H. Yasukawa, A. Suzuki, S. Kamizono, T. Syoda, I. Kinjyo, M. Sasaki, J. A. Johnston, and A. Yoshimura. 1999. Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain. Genes Cells 4:339-351.
    • (1999) Genes Cells , vol.4 , pp. 339-351
    • Sasaki, A.1    Yasukawa, H.2    Suzuki, A.3    Kamizono, S.4    Syoda, T.5    Kinjyo, I.6    Sasaki, M.7    Johnston, J.A.8    Yoshimura, A.9
  • 43
    • 0034724677 scopus 로고    scopus 로고
    • SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
    • Schmitz, J., M. Weissenbach, S. Haan, P. C. Heinrich, and F. Schaper. 2000. SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. J. Biol. Chem. 275:12848-12856.
    • (2000) J. Biol. Chem. , vol.275 , pp. 12848-12856
    • Schmitz, J.1    Weissenbach, M.2    Haan, S.3    Heinrich, P.C.4    Schaper, F.5
  • 44
    • 0037227834 scopus 로고    scopus 로고
    • Alpha-melanocyte stimulating hormone prevents lipopolysaccharide-induced vasculitis by down-regulating endothelial cell adhesion molecule expression
    • Scholzen, T. E., C. Sunderkotter, D. H. Kalden, T. Brzoska, M. Fastrich, T. Fisbeck, C. A. Armstrong, J. C. Ansel, and T. A. Luger. 2003. Alpha-melanocyte stimulating hormone prevents lipopolysaccharide-induced vasculitis by down-regulating endothelial cell adhesion molecule expression. Endocrinology 144:360-370.
    • (2003) Endocrinology , vol.144 , pp. 360-370
    • Scholzen, T.E.1    Sunderkotter, C.2    Kalden, D.H.3    Brzoska, T.4    Fastrich, M.5    Fisbeck, T.6    Armstrong, C.A.7    Ansel, J.C.8    Luger, T.A.9
  • 46
    • 33644871636 scopus 로고    scopus 로고
    • The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons
    • Shang, L., and T. B. Tomasi. 2006. The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons. J. Biol. Chem. 281:1876-1884.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1876-1884
    • Shang, L.1    Tomasi, T.B.2
  • 47
    • 13844298724 scopus 로고    scopus 로고
    • Endothelial inflammation in insulin resistance
    • Sjoholm, A., and T. Nystrom. 2005. Endothelial inflammation in insulin resistance. Lancet 365:610-612.
    • (2005) Lancet , vol.365 , pp. 610-612
    • Sjoholm, A.1    Nystrom, T.2
  • 50
    • 4344609459 scopus 로고    scopus 로고
    • The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression
    • Stevenson, N. J., S. Haan, A. E. McClurg, M. J. McGrattan, M. A. Armstrong, P. C. Heinrich, and J. A. Johnston. 2004. The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression. J. Immunol. 173:3243-3249.
    • (2004) J. Immunol. , vol.173 , pp. 3243-3249
    • Stevenson, N.J.1    Haan, S.2    McClurg, A.E.3    McGrattan, M.J.4    Armstrong, M.A.5    Heinrich, P.C.6    Johnston, J.A.7
  • 51
    • 0033197958 scopus 로고    scopus 로고
    • Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ
    • Stoiber, D., P. Kovarik, S. Cohney, J. A. Johnston, P. Steinlein, and T. Decker. 1999. Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ. J. Immunol. 163:2640-2647.
    • (1999) J. Immunol. , vol.163 , pp. 2640-2647
    • Stoiber, D.1    Kovarik, P.2    Cohney, S.3    Johnston, J.A.4    Steinlein, P.5    Decker, T.6
  • 52
    • 20444476625 scopus 로고    scopus 로고
    • SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling
    • Tanaka, T., M. A. Soriano, and M. J. Grusby. 2005. SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity 22:729-736.
    • (2005) Immunity , vol.22 , pp. 729-736
    • Tanaka, T.1    Soriano, M.A.2    Grusby, M.J.3
  • 53
    • 0347359224 scopus 로고    scopus 로고
    • Localized effects of cAMP mediated by distinct routes of protein kinase A
    • Tasken, K., and E. M. Aandahl. 2004. Localized effects of cAMP mediated by distinct routes of protein kinase A. Physiol. Rev. 84:137-167.
    • (2004) Physiol. Rev. , vol.84 , pp. 137-167
    • Tasken, K.1    Aandahl, E.M.2
  • 54
    • 0037370316 scopus 로고    scopus 로고
    • Interleukins in atherosclerosis: Molecular pathways and therapeutic potential
    • Von der Thusen, J. H., J. Kuiper, T. J. van Berkel, and E. A. Biessen. 2003. Interleukins in atherosclerosis: molecular pathways and therapeutic potential. Pharmacol. Rev. 55:133-166.
    • (2003) Pharmacol. Rev. , vol.55 , pp. 133-166
    • Von Der Thusen, J.H.1    Kuiper, J.2    Van Berkel, T.J.3    Biessen, E.A.4
  • 55
    • 0347093460 scopus 로고    scopus 로고
    • Inhibitors of cytokine signal transduction
    • Wormald, S., and D. J. Hilton. 2004. Inhibitors of cytokine signal transduction. J. Biol. Chem. 279:821-824.
    • (2004) J. Biol. Chem. , vol.279 , pp. 821-824
    • Wormald, S.1    Hilton, D.J.2
  • 59
    • 0036258332 scopus 로고    scopus 로고
    • Receptor-specific regulation of phosphatidylinositol 3′-kinase activation by the protein tyrosine phosphatase Shp2
    • Zhang, S. Q., W. G. Tsiaras, T. Araki, G. Wen, L. Minichiello, R. Klein, and B. G. Neel. 2002. Receptor-specific regulation of phosphatidylinositol 3′-kinase activation by the protein tyrosine phosphatase Shp2. Mol. Cell. Biol. 22:4062-4072.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4062-4072
    • Zhang, S.Q.1    Tsiaras, W.G.2    Araki, T.3    Wen, G.4    Minichiello, L.5    Klein, R.6    Neel, B.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.