Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A

Journal of Biological Chemistry

Volumn 283, Issue 42, 2008, Pages 28702-28709

  Yokoyama, Utako ^a   Minamisawa, Susumu ^a,b   Quan, Hong ^a   Akaike, Toru ^a   Suzuki, Sayaka ^a   Jin, Meihua ^a   Jiao, Qibin ^a   Watanabe, Mayumi ^a   Otsu, Koji ^a   Iwasaki, Shiho ^a   Nishimaki, Shigeru ^a   Sato, Motohiko ^a   Ishikawa, Yoshihiro ^a,c  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDES; CYTOLOGY; FETAL MONITORING; FUSION REACTIONS; GENE TRANSFER; INERTIAL CONFINEMENT FUSION; MUSCLE; NUCLEIC ACIDS;

CELL MIGRATIONS; CELL SHAPES; CHRONIC STIMULATIONS; FOCAL ADHESIONS; GREEN FLUORESCENT PROTEINS; HYALURONAN; HYALURONAN PRODUCTIONS; NEOINTIMAL FORMATIONS; OVEREXPRESSION; PROSTAGLANDIN E; PROTEIN KINASES; SIGNAL PATHWAYS; SMOOTH MUSCLE CELLS; STRESS FIBERS; SYNTHESIS OF;

BRAIN;

ACTIN; ADENOVIRUS VECTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; ENZYME ACTIVATOR; EPAC1 PROTEIN; EPAC2 PROTEIN; GREEN FLUORESCENT PROTEIN; HYALURONIC ACID; MESSENGER RNA; PROSTAGLANDIN E2; RAP1 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; EPAC 1 PROTEIN, RAT; EPAC-1 PROTEIN, RAT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAPGEF3 PROTEIN, HUMAN; RAPGEF4 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL SHAPE; CELL SURFACE; DUCTUS ARTERIOSUS; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE TRANSFER; GENETIC TRANSFECTION; INTIMA; MUSCLE REGENERATION; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; STRESS FIBER; UPREGULATION; WISTAR RAT; ADENOVIRUS; ANIMAL; BIOLOGICAL MODEL; CELL MOTION; DOSE RESPONSE; METABOLISM; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; RATTUS;

ADENOVIRIDAE; ANIMALS; CELL MOVEMENT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DUCTUS ARTERIOSUS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MODELS, BIOLOGICAL; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 57649120773     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804223200     Document Type: Article

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