메뉴 건너뛰기




Volumn 33, Issue 2, 2006, Pages 201-210

Mechanisms Leading to the Development of Hormone-Resistant Prostate Cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANDROSTENEDIONE; ANTIANDROGEN; ANTINEOPLASTIC AGENT; BICALUTAMIDE; CYPROTERONE ACETATE; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN; FLUTAMIDE; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; HYDROXYFLUTAMIDE; LIGAND; NUCLEAR RECEPTOR COACTIVATOR 2; PACLITAXEL; PRASTERONE; PROGESTERONE; REGULATOR PROTEIN; SMALL INTERFERING RNA; STEROID RECEPTOR COACTIVATOR 1;

EID: 33646475297     PISSN: 00940143     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ucl.2005.12.010     Document Type: Review
Times cited : (51)

References (75)
  • 1
    • 84928580276 scopus 로고
    • The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C., and Hodges C.V. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1 (1941) 293-297
    • (1941) Cancer Res , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 2
    • 22144484150 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer
    • Sharifi N., Gulley J.L., and Dahut W.L. Androgen deprivation therapy for prostate cancer. JAMA 294 (2005) 238-244
    • (2005) JAMA , vol.294 , pp. 238-244
    • Sharifi, N.1    Gulley, J.L.2    Dahut, W.L.3
  • 3
    • 10844251148 scopus 로고    scopus 로고
    • Society of Urologic Oncology position statement: redefining the management of hormone-refractory prostate carcinoma
    • Chang S.S., Benson M.C., Campbell S.C., et al. Society of Urologic Oncology position statement: redefining the management of hormone-refractory prostate carcinoma. Cancer 103 (2005) 11-21
    • (2005) Cancer , vol.103 , pp. 11-21
    • Chang, S.S.1    Benson, M.C.2    Campbell, S.C.3
  • 4
    • 0346997972 scopus 로고    scopus 로고
    • Epidemiology of prostate cancer
    • Crawford E.D. Epidemiology of prostate cancer. Urology 62 Suppl 1 (2003) 3-12
    • (2003) Urology , vol.62 , Issue.SUPPL. 1 , pp. 3-12
    • Crawford, E.D.1
  • 6
    • 22544451247 scopus 로고    scopus 로고
    • Treating the biochemical recurrence of prostate cancer after definitive primary therapy
    • Ward J.F., and Moul J.W. Treating the biochemical recurrence of prostate cancer after definitive primary therapy. Clin Prostate Cancer 4 (2005) 38-44
    • (2005) Clin Prostate Cancer , vol.4 , pp. 38-44
    • Ward, J.F.1    Moul, J.W.2
  • 8
    • 0015749215 scopus 로고
    • Proceedings: The Veterans Administration Cooperative Urological Research Group's studies of cancer of the prostate
    • Byar D.P. Proceedings: The Veterans Administration Cooperative Urological Research Group's studies of cancer of the prostate. Cancer 32 (1973) 1126-1130
    • (1973) Cancer , vol.32 , pp. 1126-1130
    • Byar, D.P.1
  • 9
    • 0031403675 scopus 로고    scopus 로고
    • Immediate versus deferred treatment for advanced prostatic cancer: initial results of the Medical Research Council Trial
    • The Medical Research Council Prostate Cancer Working Party Investigators Group. Immediate versus deferred treatment for advanced prostatic cancer: initial results of the Medical Research Council Trial. Br J Urol 79 (1997) 235-246
    • (1997) Br J Urol , vol.79 , pp. 235-246
    • The Medical Research Council Prostate Cancer Working Party Investigators Group1
  • 10
    • 12144290450 scopus 로고    scopus 로고
    • Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy
    • Moul J.W., Wu H., Sun L., et al. Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy. J Urol 171 (2004) 1141-1147
    • (2004) J Urol , vol.171 , pp. 1141-1147
    • Moul, J.W.1    Wu, H.2    Sun, L.3
  • 11
    • 0033540004 scopus 로고    scopus 로고
    • Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer
    • Messing E.M., Manola J., Sarosdy M., et al. Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer. N Engl J Med 341 (1999) 1781-1788
    • (1999) N Engl J Med , vol.341 , pp. 1781-1788
    • Messing, E.M.1    Manola, J.2    Sarosdy, M.3
  • 12
    • 0141919715 scopus 로고    scopus 로고
    • Re: disease progression and survival of patients with positive lymph nodes after radical prostatectomy. Is there a chance of cure?
    • Messing E.M. Re: disease progression and survival of patients with positive lymph nodes after radical prostatectomy. Is there a chance of cure?. J Urol 170 (2003) 1955-1956
    • (2003) J Urol , vol.170 , pp. 1955-1956
    • Messing, E.M.1
  • 13
    • 0037072063 scopus 로고    scopus 로고
    • Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial
    • Bolla M., Collette L., Blank L., et al. Long-term results with immediate androgen suppression and external irradiation in patients with locally advanced prostate cancer (an EORTC study): a phase III randomised trial. Lancet 360 (2002) 103-106
    • (2002) Lancet , vol.360 , pp. 103-106
    • Bolla, M.1    Collette, L.2    Blank, L.3
  • 14
    • 0031051097 scopus 로고    scopus 로고
    • Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy: report of Radiation Therapy Oncology Group Protocol 85-31
    • Pilepich M.V., Caplan R., Byhardt R.W., et al. Phase III trial of androgen suppression using goserelin in unfavorable-prognosis carcinoma of the prostate treated with definitive radiotherapy: report of Radiation Therapy Oncology Group Protocol 85-31. J Clin Oncol 15 (1997) 1013-1021
    • (1997) J Clin Oncol , vol.15 , pp. 1013-1021
    • Pilepich, M.V.1    Caplan, R.2    Byhardt, R.W.3
  • 15
    • 4043153049 scopus 로고    scopus 로고
    • 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial
    • D'Amico A.V., Manola J., Loffredo M., et al. 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial. JAMA 292 (2004) 821-827
    • (2004) JAMA , vol.292 , pp. 821-827
    • D'Amico, A.V.1    Manola, J.2    Loffredo, M.3
  • 16
    • 4744347762 scopus 로고    scopus 로고
    • Mechanisms of androgen-refractory prostate cancer
    • Debes J.D., and Tindall D.J. Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351 (2004) 1488-1490
    • (2004) N Engl J Med , vol.351 , pp. 1488-1490
    • Debes, J.D.1    Tindall, D.J.2
  • 17
    • 18844383164 scopus 로고    scopus 로고
    • The current role of chemotherapy in metastatic hormone-refractory prostate cancer
    • Petrylak D.P. The current role of chemotherapy in metastatic hormone-refractory prostate cancer. Urology 65 Suppl (2005) 3-7
    • (2005) Urology , vol.65 , Issue.SUPPL , pp. 3-7
    • Petrylak, D.P.1
  • 18
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman B.J., and Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 1 (2001) 34-45
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 19
    • 0026595896 scopus 로고
    • Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones
    • Kemppainen J.A., Lane M.V., Sar M., et al. Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones. J Biol Chem 267 (1992) 968-974
    • (1992) J Biol Chem , vol.267 , pp. 968-974
    • Kemppainen, J.A.1    Lane, M.V.2    Sar, M.3
  • 20
    • 1542574202 scopus 로고    scopus 로고
    • Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance
    • Holzbeierlein J., Lal P., LaTulippe E., et al. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am J Pathol 164 (2004) 217-227
    • (2004) Am J Pathol , vol.164 , pp. 217-227
    • Holzbeierlein, J.1    Lal, P.2    LaTulippe, E.3
  • 21
    • 15644368237 scopus 로고    scopus 로고
    • Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer
    • Koivisto P., Kononen J., Palmberg C., et al. Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res 57 (1997) 314-319
    • (1997) Cancer Res , vol.57 , pp. 314-319
    • Koivisto, P.1    Kononen, J.2    Palmberg, C.3
  • 22
    • 0035328474 scopus 로고    scopus 로고
    • Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer
    • Linja M.J., Savinainen K.J., Saramaki O.R., et al. Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer. Cancer Res 61 (2001) 3550-3555
    • (2001) Cancer Res , vol.61 , pp. 3550-3555
    • Linja, M.J.1    Savinainen, K.J.2    Saramaki, O.R.3
  • 23
    • 0042978480 scopus 로고    scopus 로고
    • Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
    • Edwards J., Krishna N.S., Grigor K.M., et al. Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer 89 (2003) 552-556
    • (2003) Br J Cancer , vol.89 , pp. 552-556
    • Edwards, J.1    Krishna, N.S.2    Grigor, K.M.3
  • 24
    • 20444403792 scopus 로고    scopus 로고
    • The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor
    • Edwards J., and Bartlett J.M. The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor. BJU Int 95 (2005) 1320-1326
    • (2005) BJU Int , vol.95 , pp. 1320-1326
    • Edwards, J.1    Bartlett, J.M.2
  • 25
    • 0035845558 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium
    • Stanbrough M., Leav I., Kwan P.W., et al. Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium. Proc Natl Acad Sci USA 98 (2001) 10823-10828
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10823-10828
    • Stanbrough, M.1    Leav, I.2    Kwan, P.W.3
  • 26
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen C.D., Welsbie D.S., Tran C., et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 10 (2004) 33-39
    • (2004) Nat Med , vol.10 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 27
    • 0035300409 scopus 로고    scopus 로고
    • Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
    • Gregory C.W., Johnson Jr. R.T., Mohler J.L., et al. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res 61 (2001) 2892-2898
    • (2001) Cancer Res , vol.61 , pp. 2892-2898
    • Gregory, C.W.1    Johnson Jr., R.T.2    Mohler, J.L.3
  • 28
    • 0025644325 scopus 로고
    • A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
    • Veldscholte J., Ris-Stalpers C., Kuiper G.G., et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 173 (1990) 534-540
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 534-540
    • Veldscholte, J.1    Ris-Stalpers, C.2    Kuiper, G.G.3
  • 29
    • 8244262043 scopus 로고    scopus 로고
    • Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells
    • Tan J., Sharief Y., Hamil K.G., et al. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells. Mol Endocrinol 11 (1997) 450-459
    • (1997) Mol Endocrinol , vol.11 , pp. 450-459
    • Tan, J.1    Sharief, Y.2    Hamil, K.G.3
  • 30
    • 0033152164 scopus 로고    scopus 로고
    • Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
    • Taplin M.E., Bubley G.J., Ko Y.J., et al. Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 59 (1999) 2511-2515
    • (1999) Cancer Res , vol.59 , pp. 2511-2515
    • Taplin, M.E.1    Bubley, G.J.2    Ko, Y.J.3
  • 31
    • 0042130389 scopus 로고    scopus 로고
    • Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663
    • Taplin M.E., Rajeshkumar B., Halabi S., et al. Androgen receptor mutations in androgen-independent prostate cancer: Cancer and Leukemia Group B Study 9663. J Clin Oncol 21 (2003) 2673-2678
    • (2003) J Clin Oncol , vol.21 , pp. 2673-2678
    • Taplin, M.E.1    Rajeshkumar, B.2    Halabi, S.3
  • 32
    • 12844274300 scopus 로고    scopus 로고
    • Mutation of the androgen receptor causes oncogenic transformation of the prostate
    • Han G., Buchanan G., Ittmann M., et al. Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci USA 102 (2005) 1151-1156
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1151-1156
    • Han, G.1    Buchanan, G.2    Ittmann, M.3
  • 33
    • 2642544224 scopus 로고    scopus 로고
    • The androgen receptor gene mutations database (ARDB): 2004 update
    • Gottlieb B., Beitel L.K., Wu J.H., et al. The androgen receptor gene mutations database (ARDB): 2004 update. Hum Mutat 23 (2004) 527-533
    • (2004) Hum Mutat , vol.23 , pp. 527-533
    • Gottlieb, B.1    Beitel, L.K.2    Wu, J.H.3
  • 34
    • 0034895975 scopus 로고    scopus 로고
    • Collocation of androgen receptor gene mutations in prostate cancer
    • Buchanan G., Greenberg N.M., Scher H.I., et al. Collocation of androgen receptor gene mutations in prostate cancer. Clin Cancer Res 7 (2001) 1273-1281
    • (2001) Clin Cancer Res , vol.7 , pp. 1273-1281
    • Buchanan, G.1    Greenberg, N.M.2    Scher, H.I.3
  • 35
    • 0035361340 scopus 로고    scopus 로고
    • A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
    • Gregory C.W., He B., Johnson R.T., et al. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 61 (2001) 4315-4319
    • (2001) Cancer Res , vol.61 , pp. 4315-4319
    • Gregory, C.W.1    He, B.2    Johnson, R.T.3
  • 36
    • 0029951486 scopus 로고    scopus 로고
    • Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells
    • Yeh S., and Chang C. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc Natl Acad Sci USA 93 (1996) 5517-5521
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5517-5521
    • Yeh, S.1    Chang, C.2
  • 37
    • 0032560555 scopus 로고    scopus 로고
    • Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells
    • Miyamoto H., Yeh S., Wilding G., et al. Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells. Proc Natl Acad Sci USA 95 (1998) 7379-7384
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7379-7384
    • Miyamoto, H.1    Yeh, S.2    Wilding, G.3
  • 38
    • 0033583033 scopus 로고    scopus 로고
    • Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate
    • Fujimoto N., Yeh S., Kang H.Y., et al. Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate. J Biol Chem 274 (1999) 8316-8321
    • (1999) J Biol Chem , vol.274 , pp. 8316-8321
    • Fujimoto, N.1    Yeh, S.2    Kang, H.Y.3
  • 39
    • 12344338583 scopus 로고    scopus 로고
    • Expression and function of androgen receptor coactivators in prostate cancer
    • Culig Z., Comuzzi B., Steiner H., et al. Expression and function of androgen receptor coactivators in prostate cancer. J Steroid Biochem Mol Biol 92 (2004) 265-271
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 265-271
    • Culig, Z.1    Comuzzi, B.2    Steiner, H.3
  • 40
    • 21244450722 scopus 로고    scopus 로고
    • Mechanisms of endocrine therapy-responsive and -unresponsive prostate tumours
    • Culig Z., Steiner H., Bartsch G., et al. Mechanisms of endocrine therapy-responsive and -unresponsive prostate tumours. Endocr Relat Cancer 12 (2005) 229-244
    • (2005) Endocr Relat Cancer , vol.12 , pp. 229-244
    • Culig, Z.1    Steiner, H.2    Bartsch, G.3
  • 41
    • 20444368837 scopus 로고    scopus 로고
    • The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways
    • Edwards J., and Bartlett J.M. The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: androgen-receptor cofactors and bypass pathways. BJU Int 95 (2005) 1327-1335
    • (2005) BJU Int , vol.95 , pp. 1327-1335
    • Edwards, J.1    Bartlett, J.M.2
  • 42
    • 21344441226 scopus 로고    scopus 로고
    • p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6
    • Debes J.D., Comuzzi B., Schmidt L.J., et al. p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6. Cancer Res 65 (2005) 5965-5973
    • (2005) Cancer Res , vol.65 , pp. 5965-5973
    • Debes, J.D.1    Comuzzi, B.2    Schmidt, L.J.3
  • 43
    • 23044470684 scopus 로고    scopus 로고
    • The expression and role of Foxa proteins in prostate cancer
    • In press
    • Mirosevich J., Gao N., Gupta A., et al. The expression and role of Foxa proteins in prostate cancer. Prostate (2005) In press
    • (2005) Prostate
    • Mirosevich, J.1    Gao, N.2    Gupta, A.3
  • 44
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein C.A., and Chang C. Androgen receptor in prostate cancer. Endocr Rev 25 (2004) 276-308
    • (2004) Endocr Rev , vol.25 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 45
    • 17144432214 scopus 로고    scopus 로고
    • Androgen receptor corepressors: an overview
    • Wang L., Hsu C.L., and Chang C. Androgen receptor corepressors: an overview. Prostate 63 (2005) 117-130
    • (2005) Prostate , vol.63 , pp. 117-130
    • Wang, L.1    Hsu, C.L.2    Chang, C.3
  • 46
    • 0033022342 scopus 로고    scopus 로고
    • A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
    • Craft N., Shostak Y., Carey M., et al. A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat Med 5 (1999) 280-285
    • (1999) Nat Med , vol.5 , pp. 280-285
    • Craft, N.1    Shostak, Y.2    Carey, M.3
  • 47
    • 0030888544 scopus 로고    scopus 로고
    • c-erbB-2 oncoprotein: a potential biomarker of advanced prostate cancer
    • Arai Y., Yoshiki T., and Yoshida O. c-erbB-2 oncoprotein: a potential biomarker of advanced prostate cancer. Prostate 30 (1997) 195-201
    • (1997) Prostate , vol.30 , pp. 195-201
    • Arai, Y.1    Yoshiki, T.2    Yoshida, O.3
  • 48
    • 0033545848 scopus 로고    scopus 로고
    • From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells
    • Yeh S., Lin H.K., Kang H.Y., et al. From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. Proc Natl Acad Sci USA 96 (1999) 5458-5463
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5458-5463
    • Yeh, S.1    Lin, H.K.2    Kang, H.Y.3
  • 49
    • 0034671668 scopus 로고    scopus 로고
    • HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
    • Wen Y., Hu M.C., Makino K., et al. HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Res 60 (2000) 6841-6845
    • (2000) Cancer Res , vol.60 , pp. 6841-6845
    • Wen, Y.1    Hu, M.C.2    Makino, K.3
  • 50
    • 0034637524 scopus 로고    scopus 로고
    • Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression
    • Graff J.R., Konicek B.W., McNulty A.M., et al. Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression. J Biol Chem 275 (2000) 24500-24505
    • (2000) J Biol Chem , vol.275 , pp. 24500-24505
    • Graff, J.R.1    Konicek, B.W.2    McNulty, A.M.3
  • 51
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
    • Culig Z., Hobisch A., Cronauer M.V., et al. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 54 (1994) 5474-5478
    • (1994) Cancer Res , vol.54 , pp. 5474-5478
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3
  • 52
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study
    • Chan J.M., Stampfer M.J., Giovannucci E., et al. Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279 (1998) 563-566
    • (1998) Science , vol.279 , pp. 563-566
    • Chan, J.M.1    Stampfer, M.J.2    Giovannucci, E.3
  • 53
    • 3442881895 scopus 로고    scopus 로고
    • NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice
    • Jin R.J., Wang Y., Masumori N., et al. NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice. Cancer Res 64 (2004) 5489-5495
    • (2004) Cancer Res , vol.64 , pp. 5489-5495
    • Jin, R.J.1    Wang, Y.2    Masumori, N.3
  • 54
    • 26844437741 scopus 로고    scopus 로고
    • Evaluation and clinical value of neuroendocrine differentiation in human prostatic tumors
    • Cussenot O., Villette J.M., Cochand-Priollet B., et al. Evaluation and clinical value of neuroendocrine differentiation in human prostatic tumors. Prostate Suppl 8 (1998) 43-51
    • (1998) Prostate Suppl , vol.8 , pp. 43-51
    • Cussenot, O.1    Villette, J.M.2    Cochand-Priollet, B.3
  • 55
    • 12344252767 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostate cancer: implications for new treatment modalities
    • Vashchenko N., and Abrahamsson P.A. Neuroendocrine differentiation in prostate cancer: implications for new treatment modalities. Eur Urol 47 (2005) 147-155
    • (2005) Eur Urol , vol.47 , pp. 147-155
    • Vashchenko, N.1    Abrahamsson, P.A.2
  • 56
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T., Morrison S.J., Clarke M.F., et al. Stem cells, cancer, and cancer stem cells. Nature 414 (2001) 105-111
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3
  • 57
    • 0028294877 scopus 로고
    • Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers
    • Sell S., and Pierce G.B. Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Lab Invest 70 (1994) 6-22
    • (1994) Lab Invest , vol.70 , pp. 6-22
    • Sell, S.1    Pierce, G.B.2
  • 58
    • 0024832529 scopus 로고
    • Etiology and disease process of benign prostatic hyperplasia
    • Isaacs J.T., and Coffey D.S. Etiology and disease process of benign prostatic hyperplasia. Prostate Suppl 2 (1989) 33-50
    • (1989) Prostate Suppl , vol.2 , pp. 33-50
    • Isaacs, J.T.1    Coffey, D.S.2
  • 59
    • 0031683673 scopus 로고    scopus 로고
    • Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells
    • De Marzo A.M., Meeker A.K., Epstein J.I., et al. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. Am J Pathol 153 (1998) 911-919
    • (1998) Am J Pathol , vol.153 , pp. 911-919
    • De Marzo, A.M.1    Meeker, A.K.2    Epstein, J.I.3
  • 60
    • 0036789665 scopus 로고    scopus 로고
    • Neuroendocrine differentiation of human prostatic primary epithelial cells in vitro
    • Rumpold H., Heinrich E., Untergasser G., et al. Neuroendocrine differentiation of human prostatic primary epithelial cells in vitro. Prostate 53 (2002) 101-108
    • (2002) Prostate , vol.53 , pp. 101-108
    • Rumpold, H.1    Heinrich, E.2    Untergasser, G.3
  • 61
    • 0344417912 scopus 로고    scopus 로고
    • Neurogenic origin of human prostate endocrine cells
    • Aumuller G., Leonhardt M., Janssen M., et al. Neurogenic origin of human prostate endocrine cells. Urology 53 (1999) 1041-1048
    • (1999) Urology , vol.53 , pp. 1041-1048
    • Aumuller, G.1    Leonhardt, M.2    Janssen, M.3
  • 62
    • 8444232003 scopus 로고    scopus 로고
    • Role of p63 and basal cells in the prostate
    • Kurita T., Medina R.T., Mills A.A., et al. Role of p63 and basal cells in the prostate. Development 131 (2004) 4955-4964
    • (2004) Development , vol.131 , pp. 4955-4964
    • Kurita, T.1    Medina, R.T.2    Mills, A.A.3
  • 63
    • 0035495974 scopus 로고    scopus 로고
    • Cell differentiation lineage in the prostate
    • Wang Y., Hayward S., Cao M., et al. Cell differentiation lineage in the prostate. Differentiation 68 (2001) 270-279
    • (2001) Differentiation , vol.68 , pp. 270-279
    • Wang, Y.1    Hayward, S.2    Cao, M.3
  • 64
    • 0031897190 scopus 로고    scopus 로고
    • Identification of intermediate cell types by keratin expression in the developing human prostate
    • Xue Y., Smedts F., Debruyne F.M., et al. Identification of intermediate cell types by keratin expression in the developing human prostate. Prostate 34 (1998) 292-301
    • (1998) Prostate , vol.34 , pp. 292-301
    • Xue, Y.1    Smedts, F.2    Debruyne, F.M.3
  • 65
    • 0035177262 scopus 로고    scopus 로고
    • Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression
    • Collins A.T., Habib F.K., Maitland N.J., et al. Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression. J Cell Sci 114 (2001) 3865-3872
    • (2001) J Cell Sci , vol.114 , pp. 3865-3872
    • Collins, A.T.1    Habib, F.K.2    Maitland, N.J.3
  • 66
    • 0033901247 scopus 로고    scopus 로고
    • Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells
    • Hudson D.L., O'Hare M., Watt F.M., et al. Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells. Lab Invest 80 (2000) 1243-1250
    • (2000) Lab Invest , vol.80 , pp. 1243-1250
    • Hudson, D.L.1    O'Hare, M.2    Watt, F.M.3
  • 67
    • 23044510643 scopus 로고    scopus 로고
    • Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells
    • Huss W.J., Gray D.R., Greenberg N.M., et al. Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Res 65 (2005) 6640-6650
    • (2005) Cancer Res , vol.65 , pp. 6640-6650
    • Huss, W.J.1    Gray, D.R.2    Greenberg, N.M.3
  • 68
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery J.P. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2 (2002) 442-454
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 69
    • 0043172396 scopus 로고    scopus 로고
    • Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
    • Grunert S., Jechlinger M., and Beug H. Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol 4 (2003) 657-665
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 657-665
    • Grunert, S.1    Jechlinger, M.2    Beug, H.3
  • 70
    • 0347052797 scopus 로고    scopus 로고
    • Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis
    • Gotzmann J., Mikula M., Eger A., et al. Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res 566 (2004) 9-20
    • (2004) Mutat Res , vol.566 , pp. 9-20
    • Gotzmann, J.1    Mikula, M.2    Eger, A.3
  • 71
    • 0030271472 scopus 로고    scopus 로고
    • Desmosomes: differentiation, development, dynamics and disease
    • Garrod D., Chidgey M., and North A. Desmosomes: differentiation, development, dynamics and disease. Curr Opin Cell Biol 8 (1996) 670-678
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 670-678
    • Garrod, D.1    Chidgey, M.2    North, A.3
  • 72
    • 0033930954 scopus 로고    scopus 로고
    • E-cadherin-catenin cell-cell adhesion complex and human cancer
    • Wijnhoven B.P., Dinjens W.N., and Pignatelli M. E-cadherin-catenin cell-cell adhesion complex and human cancer. Br J Surg 87 (2000) 992-1005
    • (2000) Br J Surg , vol.87 , pp. 992-1005
    • Wijnhoven, B.P.1    Dinjens, W.N.2    Pignatelli, M.3
  • 73
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl A.K., Wilgenbus P., Dahl U., et al. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392 (1998) 190-193
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3
  • 74
    • 20444453337 scopus 로고    scopus 로고
    • Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
    • Kwok W.K., Ling M.T., Lee T.W., et al. Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Res 65 (2005) 5153-5162
    • (2005) Cancer Res , vol.65 , pp. 5153-5162
    • Kwok, W.K.1    Ling, M.T.2    Lee, T.W.3
  • 75
    • 26944435866 scopus 로고    scopus 로고
    • Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells
    • Veveris-Lowe T.L., Lawrence M.G., Collard R.L., et al. Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells. Endocr Relat Cancer 12 (2005) 631-643
    • (2005) Endocr Relat Cancer , vol.12 , pp. 631-643
    • Veveris-Lowe, T.L.1    Lawrence, M.G.2    Collard, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.