메뉴 건너뛰기




Volumn 4, Issue , 2010, Pages

Stochastic modeling of b lymphocyte terminal differentiation and its suppression by dioxin

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; IMMUNOGLOBULIN M; LIPOPOLYSACCHARIDE;

EID: 77950525353     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-4-40     Document Type: Article
Times cited : (23)

References (104)
  • 1
    • 14944362858 scopus 로고    scopus 로고
    • Regulation of plasma-cell development
    • 10.1038/nri1572, 15738953
    • Shapiro-Shelef M, Calame K. Regulation of plasma-cell development. Nat Rev Immunol 2005, 5:230-242. 10.1038/nri1572, 15738953.
    • (2005) Nat Rev Immunol , vol.5 , pp. 230-242
    • Shapiro-Shelef, M.1    Calame, K.2
  • 2
    • 0035194463 scopus 로고    scopus 로고
    • Plasma cells: finding new light at the end of B cell development
    • 10.1038/ni1201-1103, 11725300
    • Calame KL. Plasma cells: finding new light at the end of B cell development. Nat Immunol 2001, 2:1103-1108. 10.1038/ni1201-1103, 11725300.
    • (2001) Nat Immunol , vol.2 , pp. 1103-1108
    • Calame, K.L.1
  • 3
    • 45549105388 scopus 로고    scopus 로고
    • Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate
    • 10.1093/toxsci/kfn059, 18359764
    • Peden-Adams MM, Keller JM, Eudaly JG, Berger J, Gilkeson GS, Keil DE. Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate. Toxicol Sci 2008, 104:144-154. 10.1093/toxsci/kfn059, 18359764.
    • (2008) Toxicol Sci , vol.104 , pp. 144-154
    • Peden-Adams, M.M.1    Keller, J.M.2    Eudaly, J.G.3    Berger, J.4    Gilkeson, G.S.5    Keil, D.E.6
  • 4
    • 24044462926 scopus 로고    scopus 로고
    • The polysaccharide antibody response after Streptococcus pneumoniae vaccination is differentially enhanced or suppressed by 3,4-dichloropropionanilide and 2,4-dichlorophenoxyacetic acid
    • 10.1093/toxsci/kfi244, 15976183
    • Salazar KD, de la Rosa P, Barnett JB, Schafer R. The polysaccharide antibody response after Streptococcus pneumoniae vaccination is differentially enhanced or suppressed by 3,4-dichloropropionanilide and 2,4-dichlorophenoxyacetic acid. Toxicol Sci 2005, 87:123-133. 10.1093/toxsci/kfi244, 15976183.
    • (2005) Toxicol Sci , vol.87 , pp. 123-133
    • Salazar, K.D.1    de la Rosa, P.2    Barnett, J.B.3    Schafer, R.4
  • 5
    • 0024237673 scopus 로고
    • Elucidation of cellular targets responsible for tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of antibody responses: I. The role of the B lymphocyte
    • 10.1016/0162-3109(88)90005-7, 3267010
    • Dooley RK, Holsapple MP. Elucidation of cellular targets responsible for tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of antibody responses: I. The role of the B lymphocyte. Immunopharmacology 1988, 16:167-180. 10.1016/0162-3109(88)90005-7, 3267010.
    • (1988) Immunopharmacology , vol.16 , pp. 167-180
    • Dooley, R.K.1    Holsapple, M.P.2
  • 6
    • 0022504971 scopus 로고
    • Suppression of B cell differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Tucker AN, Vore SJ, Luster MI. Suppression of B cell differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Pharmacol 1986, 29:372-377.
    • (1986) Mol Pharmacol , vol.29 , pp. 372-377
    • Tucker, A.N.1    Vore, S.J.2    Luster, M.I.3
  • 7
    • 0031956114 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-dependent suppression by 2,3,7, 8-tetrachlorodibenzo-p-dioxin of IgM secretion in activated B cells
    • Sulentic CE, Holsapple MP, Kaminski NE. Aryl hydrocarbon receptor-dependent suppression by 2,3,7, 8-tetrachlorodibenzo-p-dioxin of IgM secretion in activated B cells. Mol Pharmacol 1998, 53:623-629.
    • (1998) Mol Pharmacol , vol.53 , pp. 623-629
    • Sulentic, C.E.1    Holsapple, M.P.2    Kaminski, N.E.3
  • 8
    • 0036147662 scopus 로고    scopus 로고
    • Recent advances in understanding the mechanisms of TCDD immunotoxicity
    • 10.1016/S1567-5769(01)00179-5, 11811931
    • Kerkvliet NI. Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int Immunopharmacol 2002, 2:277-291. 10.1016/S1567-5769(01)00179-5, 11811931.
    • (2002) Int Immunopharmacol , vol.2 , pp. 277-291
    • Kerkvliet, N.I.1
  • 9
    • 0020010617 scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity
    • 10.1146/annurev.pa.22.040182.002505, 6282188
    • Poland A, Knutson JC. 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 1982, 22:517-554. 10.1146/annurev.pa.22.040182.002505, 6282188.
    • (1982) Annu Rev Pharmacol Toxicol , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 10
    • 34248199004 scopus 로고    scopus 로고
    • Bifurcation dynamics in lineage-commitment in bipotent progenitor cells
    • 10.1016/j.ydbio.2007.02.036, 17412320
    • Huang S, Guo YP, May G, Enver T. Bifurcation dynamics in lineage-commitment in bipotent progenitor cells. Dev Biol 2007, 305:695-713. 10.1016/j.ydbio.2007.02.036, 17412320.
    • (2007) Dev Biol , vol.305 , pp. 695-713
    • Huang, S.1    Guo, Y.P.2    May, G.3    Enver, T.4
  • 11
    • 33749350211 scopus 로고    scopus 로고
    • Transcriptional dynamics of the embryonic stem cell switch
    • 10.1371/journal.pcbi.0020123, 1570179,1570179, 16978048
    • Chickarmane V, Troein C, Nuber UA, Sauro HM, Peterson C. Transcriptional dynamics of the embryonic stem cell switch. PLoS Comput Biol 2006, 2:e123. 10.1371/journal.pcbi.0020123, 1570179,1570179, 16978048.
    • (2006) PLoS Comput Biol , vol.2
    • Chickarmane, V.1    Troein, C.2    Nuber, U.A.3    Sauro, H.M.4    Peterson, C.5
  • 12
    • 34547604468 scopus 로고    scopus 로고
    • Noise in gene expression determines cell fate in Bacillus subtilis
    • 10.1126/science.1140818, 17569828
    • Maamar H, Raj A, Dubnau D. Noise in gene expression determines cell fate in Bacillus subtilis. Science 2007, 317:526-529. 10.1126/science.1140818, 17569828.
    • (2007) Science , vol.317 , pp. 526-529
    • Maamar, H.1    Raj, A.2    Dubnau, D.3
  • 13
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • 10.1038/nrm2066, 17139329
    • Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006, 7:885-896. 10.1038/nrm2066, 17139329.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 14
    • 45449094567 scopus 로고    scopus 로고
    • Activation-dependent induction of Blimp-1
    • 10.1016/j.coi.2008.04.010, 18554885
    • Calame K. Activation-dependent induction of Blimp-1. Curr Opin Immunol 2008, 20:259-264. 10.1016/j.coi.2008.04.010, 18554885.
    • (2008) Curr Opin Immunol , vol.20 , pp. 259-264
    • Calame, K.1
  • 15
    • 0036272784 scopus 로고    scopus 로고
    • Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells
    • 10.1128/MCB.22.13.4771-4780.2002, 133916, 12052884
    • Lin KI, Angelin-Duclos C, Kuo TC, Calame K. Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol Cell Biol 2002, 22:4771-4780. 10.1128/MCB.22.13.4771-4780.2002, 133916, 12052884.
    • (2002) Mol Cell Biol , vol.22 , pp. 4771-4780
    • Lin, K.I.1    Angelin-Duclos, C.2    Kuo, T.C.3    Calame, K.4
  • 17
    • 2142750272 scopus 로고    scopus 로고
    • Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation
    • Sciammas R, Davis MM. Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation. J Immunol 2004, 172:5427-5440.
    • (2004) J Immunol , vol.172 , pp. 5427-5440
    • Sciammas, R.1    Davis, M.M.2
  • 18
    • 0037103133 scopus 로고    scopus 로고
    • Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene
    • Vasanwala FH, Kusam S, Toney LM, Dent AL. Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene. J Immunol 2002, 169:1922-1929.
    • (2002) J Immunol , vol.169 , pp. 1922-1929
    • Vasanwala, F.H.1    Kusam, S.2    Toney, L.M.3    Dent, A.L.4
  • 20
    • 36148934909 scopus 로고    scopus 로고
    • Human BSAP and BLIMP1 conform an autoregulatory feedback loop
    • 10.1182/blood-2007-05-092262, 17682124
    • Mora-Lopez F, Reales E, Brieva JA, Campos-Caro A. Human BSAP and BLIMP1 conform an autoregulatory feedback loop. Blood 2007, 110:3150-3157. 10.1182/blood-2007-05-092262, 17682124.
    • (2007) Blood , vol.110 , pp. 3150-3157
    • Mora-Lopez, F.1    Reales, E.2    Brieva, J.A.3    Campos-Caro, A.4
  • 21
    • 79551684408 scopus 로고    scopus 로고
    • A Bistable Switch Underlying B Cell Differentiation and Its Disruption by the Environmental Contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • doi: 10.1093/toxsci/kfq1035
    • Bhattacharya S, Conolly RB, Kaminski NE, Thomas RS, Andersen ME, Zhang Q. A Bistable Switch Underlying B Cell Differentiation and Its Disruption by the Environmental Contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci 2010, doi: 10.1093/toxsci/kfq1035.
    • (2010) Toxicol Sci
    • Bhattacharya, S.1    Conolly, R.B.2    Kaminski, N.E.3    Thomas, R.S.4    Andersen, M.E.5    Zhang, Q.6
  • 22
    • 0033565270 scopus 로고    scopus 로고
    • Differential involvement of the transcription factor Blimp-1 in T cell-independent and -dependent B cell differentiation to plasma cells
    • Soro PG, Morales AP, Martinez MJ, Morales AS, Copin SG, Marcos MA, Gaspar ML. Differential involvement of the transcription factor Blimp-1 in T cell-independent and -dependent B cell differentiation to plasma cells. J Immunol 1999, 163:611-617.
    • (1999) J Immunol , vol.163 , pp. 611-617
    • Soro, P.G.1    Morales, A.P.2    Martinez, M.J.3    Morales, A.S.4    Copin, S.G.5    Marcos, M.A.6    Gaspar, M.L.7
  • 23
    • 7244231012 scopus 로고    scopus 로고
    • Plasma cell ontogeny defined by quantitative changes in blimp-1 expression
    • 10.1084/jem.20040973, 2211847, 15492122
    • Kallies A, Hasbold J, Tarlinton DM, Dietrich W, Corcoran LM, Hodgkin PD, Nutt SL. Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med 2004, 200:967-977. 10.1084/jem.20040973, 2211847, 15492122.
    • (2004) J Exp Med , vol.200 , pp. 967-977
    • Kallies, A.1    Hasbold, J.2    Tarlinton, D.M.3    Dietrich, W.4    Corcoran, L.M.5    Hodgkin, P.D.6    Nutt, S.L.7
  • 26
    • 33745182931 scopus 로고    scopus 로고
    • Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
    • 10.1038/ni1357, 16767092
    • Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R. Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol 2006, 7:773-782. 10.1038/ni1357, 16767092.
    • (2006) Nat Immunol , vol.7 , pp. 773-782
    • Klein, U.1    Casola, S.2    Cattoretti, G.3    Shen, Q.4    Lia, M.5    Mo, T.6    Ludwig, T.7    Rajewsky, K.8    Dalla-Favera, R.9
  • 27
    • 17044386646 scopus 로고    scopus 로고
    • Regulatory events in early and late B-cell differentiation
    • 10.1016/j.molimm.2004.06.039, 15829263
    • Johnson K, Shapiro-Shelef M, Tunyaplin C, Calame K. Regulatory events in early and late B-cell differentiation. Mol Immunol 2005, 42:749-761. 10.1016/j.molimm.2004.06.039, 15829263.
    • (2005) Mol Immunol , vol.42 , pp. 749-761
    • Johnson, K.1    Shapiro-Shelef, M.2    Tunyaplin, C.3    Calame, K.4
  • 28
    • 34247188078 scopus 로고    scopus 로고
    • Pax5: the guardian of B cell identity and function
    • 10.1038/ni1454, 17440452
    • Cobaleda C, Schebesta A, Delogu A, Busslinger M. Pax5: the guardian of B cell identity and function. Nat Immunol 2007, 8:463-470. 10.1038/ni1454, 17440452.
    • (2007) Nat Immunol , vol.8 , pp. 463-470
    • Cobaleda, C.1    Schebesta, A.2    Delogu, A.3    Busslinger, M.4
  • 29
    • 33644978463 scopus 로고    scopus 로고
    • Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells
    • 10.1016/j.immuni.2006.01.012, 16546096
    • Delogu A, Schebesta A, Sun Q, Aschenbrenner K, Perlot T, Busslinger M. Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity 2006, 24:269-281. 10.1016/j.immuni.2006.01.012, 16546096.
    • (2006) Immunity , vol.24 , pp. 269-281
    • Delogu, A.1    Schebesta, A.2    Sun, Q.3    Aschenbrenner, K.4    Perlot, T.5    Busslinger, M.6
  • 30
  • 31
    • 0032128002 scopus 로고    scopus 로고
    • Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor
    • 10.1101/gad.12.13.1953, 316953, 9649500
    • Niu H, Ye BH, Dalla-Favera R. Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev 1998, 12:1953-1961. 10.1101/gad.12.13.1953, 316953, 9649500.
    • (1998) Genes Dev , vol.12 , pp. 1953-1961
    • Niu, H.1    Ye, B.H.2    Dalla-Favera, R.3
  • 32
    • 33749522228 scopus 로고    scopus 로고
    • ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation
    • Rui L, Healy JI, Blasioli J, Goodnow CC. ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation. J Immunol 2006, 177:5337-5346.
    • (2006) J Immunol , vol.177 , pp. 5337-5346
    • Rui, L.1    Healy, J.I.2    Blasioli, J.3    Goodnow, C.C.4
  • 33
    • 33846187999 scopus 로고    scopus 로고
    • STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas
    • 10.1038/sj.onc.1209775, 16819511
    • Walker SR, Nelson EA, Frank DA. STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Oncogene 2007, 26:224-233. 10.1038/sj.onc.1209775, 16819511.
    • (2007) Oncogene , vol.26 , pp. 224-233
    • Walker, S.R.1    Nelson, E.A.2    Frank, D.A.3
  • 35
    • 0036607704 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-dependent inhibition of AP-1 activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in activated B cells
    • 10.1006/taap.2002.9403, 12051995
    • Suh J, Jeon YJ, Kim HM, Kang JS, Kaminski NE, Yang KH. Aryl hydrocarbon receptor-dependent inhibition of AP-1 activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in activated B cells. Toxicol Appl Pharmacol 2002, 181:116-123. 10.1006/taap.2002.9403, 12051995.
    • (2002) Toxicol Appl Pharmacol , vol.181 , pp. 116-123
    • Suh, J.1    Jeon, Y.J.2    Kim, H.M.3    Kang, J.S.4    Kaminski, N.E.5    Yang, K.H.6
  • 36
    • 64349123334 scopus 로고    scopus 로고
    • Involvement of Blimp-1 and AP-1 dysregulation in the 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated suppression of the IgM response by B cells
    • 10.1093/toxsci/kfp028, 2664693, 19237549
    • Schneider D, Manzan MA, Yoo BS, Crawford RB, Kaminski N. Involvement of Blimp-1 and AP-1 dysregulation in the 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated suppression of the IgM response by B cells. Toxicol Sci 2009, 108:377-388. 10.1093/toxsci/kfp028, 2664693, 19237549.
    • (2009) Toxicol Sci , vol.108 , pp. 377-388
    • Schneider, D.1    Manzan, M.A.2    Yoo, B.S.3    Crawford, R.B.4    Kaminski, N.5
  • 37
    • 1642276713 scopus 로고    scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin, an exogenous modulator of the 3'alpha immunoglobulin heavy chain enhancer in the CH12.LX mouse cell line
    • 10.1124/jpet.103.059493, 14718603
    • Sulentic CE, Zhang W, Na YJ, Kaminski NE. 2,3,7,8-tetrachlorodibenzo-p-dioxin, an exogenous modulator of the 3'alpha immunoglobulin heavy chain enhancer in the CH12.LX mouse cell line. J Pharmacol Exp Ther 2004, 309:71-78. 10.1124/jpet.103.059493, 14718603.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 71-78
    • Sulentic, C.E.1    Zhang, W.2    Na, Y.J.3    Kaminski, N.E.4
  • 38
    • 19544379881 scopus 로고    scopus 로고
    • Stochasticity in gene expression: from theories to phenotypes
    • 10.1038/nrg1615, 15883588
    • Kaern M, Elston TC, Blake WJ, Collins JJ. Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet 2005, 6:451-464. 10.1038/nrg1615, 15883588.
    • (2005) Nat Rev Genet , vol.6 , pp. 451-464
    • Kaern, M.1    Elston, T.C.2    Blake, W.J.3    Collins, J.J.4
  • 39
    • 0035902599 scopus 로고    scopus 로고
    • Intrinsic noise in gene regulatory networks
    • 10.1073/pnas.151588598, 37484, 11438714
    • Thattai M, van Oudenaarden A. Intrinsic noise in gene regulatory networks. Proc Natl Acad Sci USA 2001, 98:8614-8619. 10.1073/pnas.151588598, 37484, 11438714.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8614-8619
    • Thattai, M.1    van Oudenaarden, A.2
  • 40
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • 10.1126/science.1070919, 12183631
    • Elowitz MB, Levine AJ, Siggia ED, Swain PS. Stochastic gene expression in a single cell. Science 2002, 297:1183-1186. 10.1126/science.1070919, 12183631.
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 42
    • 0036790975 scopus 로고    scopus 로고
    • Intrinsic and extrinsic contributions to stochasticity in gene expression
    • 10.1073/pnas.162041399, 130539, 12237400
    • Swain PS, Elowitz MB, Siggia ED. Intrinsic and extrinsic contributions to stochasticity in gene expression. Proc Natl Acad Sci USA 2002, 99:12795-12800. 10.1073/pnas.162041399, 130539, 12237400.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12795-12800
    • Swain, P.S.1    Elowitz, M.B.2    Siggia, E.D.3
  • 43
    • 0242416539 scopus 로고    scopus 로고
    • Noise in eukaryotic gene expression
    • 10.1038/nature01546, 12687005
    • Blake WJ, M KA, Cantor CR, Collins JJ. Noise in eukaryotic gene expression. Nature 2003, 422:633-637. 10.1038/nature01546, 12687005.
    • (2003) Nature , vol.422 , pp. 633-637
    • Blake, W.J.1    M, K.A.2    Cantor, C.R.3    Collins, J.J.4
  • 44
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • 10.1126/science.1098641, 1410811, 15166317
    • Raser JM, O'Shea EK. Control of stochasticity in eukaryotic gene expression. Science 2004, 304:1811-1814. 10.1126/science.1098641, 1410811, 15166317.
    • (2004) Science , vol.304 , pp. 1811-1814
    • Raser, J.M.1    O'Shea, E.K.2
  • 45
    • 66249136447 scopus 로고    scopus 로고
    • Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
    • 10.1038/nature08012, 19363473
    • Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 2009, 459:428-432. 10.1038/nature08012, 19363473.
    • (2009) Nature , vol.459 , pp. 428-432
    • Spencer, S.L.1    Gaudet, S.2    Albeck, J.G.3    Burke, J.M.4    Sorger, P.K.5
  • 46
    • 66149084052 scopus 로고    scopus 로고
    • Exploring the roles of noise in the eukaryotic cell cycle
    • 10.1073/pnas.0810034106, 2672517, 19246388
    • Kar S, Baumann WT, Paul MR, Tyson JJ. Exploring the roles of noise in the eukaryotic cell cycle. Proc Natl Acad Sci USA 2009, 106:6471-6476. 10.1073/pnas.0810034106, 2672517, 19246388.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6471-6476
    • Kar, S.1    Baumann, W.T.2    Paul, M.R.3    Tyson, J.J.4
  • 47
    • 33644856456 scopus 로고    scopus 로고
    • Stochastic spineless expression creates the retinal mosaic for colour vision
    • 10.1038/nature04615, 16525464
    • Wernet MF, Mazzoni EO, Celik A, Duncan DM, Duncan I, Desplan C. Stochastic spineless expression creates the retinal mosaic for colour vision. Nature 2006, 440:174-180. 10.1038/nature04615, 16525464.
    • (2006) Nature , vol.440 , pp. 174-180
    • Wernet, M.F.1    Mazzoni, E.O.2    Celik, A.3    Duncan, D.M.4    Duncan, I.5    Desplan, C.6
  • 48
    • 59649122396 scopus 로고    scopus 로고
    • Suppression of T cell costimulator ICOS by Delta9-tetrahydrocannabinol
    • 10.1189/jlb.0608390, 2631366, 18988696
    • Lu H, Kaplan BL, Ngaotepprutaram T, Kaminski NE. Suppression of T cell costimulator ICOS by Delta9-tetrahydrocannabinol. J Leukoc Biol 2009, 85:322-329. 10.1189/jlb.0608390, 2631366, 18988696.
    • (2009) J Leukoc Biol , vol.85 , pp. 322-329
    • Lu, H.1    Kaplan, B.L.2    Ngaotepprutaram, T.3    Kaminski, N.E.4
  • 49
    • 57149109403 scopus 로고    scopus 로고
    • Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Delta9-tetrahydrocannabinol
    • 10.1189/jlb.0508282, 2614598, 18791168
    • Springs AE, Karmaus PW, Crawford RB, Kaplan BL, Kaminski NE. Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Delta9-tetrahydrocannabinol. J Leukoc Biol 2008, 84:1574-1584. 10.1189/jlb.0508282, 2614598, 18791168.
    • (2008) J Leukoc Biol , vol.84 , pp. 1574-1584
    • Springs, A.E.1    Karmaus, P.W.2    Crawford, R.B.3    Kaplan, B.L.4    Kaminski, N.E.5
  • 50
    • 0034048586 scopus 로고    scopus 로고
    • To be or not to be active: the stochastic nature of enhancer action
    • 10.1002/(SICI)1521-1878(200004)22:4<381::AID-BIES8>3.0.CO;2-E, 10723035
    • Fiering S, Whitelaw E, Martin DI. To be or not to be active: the stochastic nature of enhancer action. Bioessays 2000, 22:381-387. 10.1002/(SICI)1521-1878(200004)22:4<381::AID-BIES8>3.0.CO;2-E, 10723035.
    • (2000) Bioessays , vol.22 , pp. 381-387
    • Fiering, S.1    Whitelaw, E.2    Martin, D.I.3
  • 51
    • 33745807247 scopus 로고    scopus 로고
    • Binary Gene Induction and Protein Expression in Individual Cells
    • 10.1186/1742-4682-3-18, 1488830, 16597340
    • Zhang Q, Andersen ME, Conolly RB. Binary Gene Induction and Protein Expression in Individual Cells. Theor Biol Med Model 2006, 3:18. 10.1186/1742-4682-3-18, 1488830, 16597340.
    • (2006) Theor Biol Med Model , vol.3 , pp. 18
    • Zhang, Q.1    Andersen, M.E.2    Conolly, R.B.3
  • 52
    • 0034073382 scopus 로고    scopus 로고
    • Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase
    • 10.1128/MCB.20.7.2592-2603.2000, 85475, 10713181
    • Yu J, Angelin-Duclos C, Greenwood J, Liao J, Calame K. Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol Cell Biol 2000, 20:2592-2603. 10.1128/MCB.20.7.2592-2603.2000, 85475, 10713181.
    • (2000) Mol Cell Biol , vol.20 , pp. 2592-2603
    • Yu, J.1    Angelin-Duclos, C.2    Greenwood, J.3    Liao, J.4    Calame, K.5
  • 53
    • 1542347557 scopus 로고    scopus 로고
    • PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing
    • 10.1038/ni1046, 14985713
    • Gyory I, Wu J, Fejer G, Seto E, Wright KL. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nat Immunol 2004, 5:299-308. 10.1038/ni1046, 14985713.
    • (2004) Nat Immunol , vol.5 , pp. 299-308
    • Gyory, I.1    Wu, J.2    Fejer, G.3    Seto, E.4    Wright, K.L.5
  • 54
    • 0032947592 scopus 로고    scopus 로고
    • PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins
    • 10.1101/gad.13.1.125, 316372, 9887105
    • Ren B, Chee KJ, Kim TH, Maniatis T. PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins. Genes Dev 1999, 13:125-137. 10.1101/gad.13.1.125, 316372, 9887105.
    • (1999) Genes Dev , vol.13 , pp. 125-137
    • Ren, B.1    Chee, K.J.2    Kim, T.H.3    Maniatis, T.4
  • 55
    • 0036040358 scopus 로고    scopus 로고
    • A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes
    • 10.1046/j.1365-2567.2002.01456.x, 1782747, 12153506
    • Milili M, Gauthier L, Veran J, Mattei MG, Schiff C. A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes. Immunology 2002, 106:447-455. 10.1046/j.1365-2567.2002.01456.x, 1782747, 12153506.
    • (2002) Immunology , vol.106 , pp. 447-455
    • Milili, M.1    Gauthier, L.2    Veran, J.3    Mattei, M.G.4    Schiff, C.5
  • 56
    • 0343183096 scopus 로고    scopus 로고
    • Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family
    • 10.1093/emboj/19.10.2292, 384353, 10811620
    • Eberhard D, Jimenez G, Heavey B, Busslinger M. Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. Embo J 2000, 19:2292-2303. 10.1093/emboj/19.10.2292, 384353, 10811620.
    • (2000) Embo J , vol.19 , pp. 2292-2303
    • Eberhard, D.1    Jimenez, G.2    Heavey, B.3    Busslinger, M.4
  • 57
    • 33644508366 scopus 로고    scopus 로고
    • Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
    • 10.1038/sj.emboj.7600991, 1383569, 16467847
    • Husebye H, Halaas O, Stenmark H, Tunheim G, Sandanger O, Bogen B, Brech A, Latz E, Espevik T. Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Embo J 2006, 25:683-692. 10.1038/sj.emboj.7600991, 1383569, 16467847.
    • (2006) Embo J , vol.25 , pp. 683-692
    • Husebye, H.1    Halaas, O.2    Stenmark, H.3    Tunheim, G.4    Sandanger, O.5    Bogen, B.6    Brech, A.7    Latz, E.8    Espevik, T.9
  • 58
    • 0032533474 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide can enter monocytes via two CD14-dependent pathways
    • Kitchens RL, Wang P, Munford RS. Bacterial lipopolysaccharide can enter monocytes via two CD14-dependent pathways. J Immunol 1998, 161:5534-5545.
    • (1998) J Immunol , vol.161 , pp. 5534-5545
    • Kitchens, R.L.1    Wang, P.2    Munford, R.S.3
  • 59
    • 2942514591 scopus 로고    scopus 로고
    • Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
    • 10.1186/1471-2105-5-24, 408466, 15113411
    • Adalsteinsson D, McMillen D, Elston TC. Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks. BMC Bioinformatics 2004, 5:24. 10.1186/1471-2105-5-24, 408466, 15113411.
    • (2004) BMC Bioinformatics , vol.5 , pp. 24
    • Adalsteinsson, D.1    McMillen, D.2    Elston, T.C.3
  • 60
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie DT. Exact stochastic simulation of coupled chemical reactions. Journal of Physical Chemistry 1977, 81:2340-2361.
    • (1977) Journal of Physical Chemistry , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 62
    • 0037605637 scopus 로고    scopus 로고
    • Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
    • 10.1063/1.1349894, 12779456
    • Ferrell JE, Xiong W. Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. Chaos 2001, 11:227-236. 10.1063/1.1349894, 12779456.
    • (2001) Chaos , vol.11 , pp. 227-236
    • Ferrell, J.E.1    Xiong, W.2
  • 63
    • 1242274449 scopus 로고    scopus 로고
    • Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
    • 10.1073/pnas.0308265100, 357011, 14766974
    • Angeli D, Ferrell JE, Sontag ED. Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc Natl Acad Sci USA 2004, 101:1822-1827. 10.1073/pnas.0308265100, 357011, 14766974.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1822-1827
    • Angeli, D.1    Ferrell, J.E.2    Sontag, E.D.3
  • 65
    • 0023688658 scopus 로고
    • Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion
    • Swain SL, Dutton RW, McKenzie D, Helstrom H, English M. Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol 1988, 140:4224-4230.
    • (1988) J Immunol , vol.140 , pp. 4224-4230
    • Swain, S.L.1    Dutton, R.W.2    McKenzie, D.3    Helstrom, H.4    English, M.5
  • 66
    • 23444459544 scopus 로고
    • Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells
    • 10.1016/0092-8674(94)90321-2, 8168136
    • Turner CA, Mack DH, Davis MM. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell 1994, 77:297-306. 10.1016/0092-8674(94)90321-2, 8168136.
    • (1994) Cell , vol.77 , pp. 297-306
    • Turner, C.A.1    Mack, D.H.2    Davis, M.M.3
  • 67
    • 58049211935 scopus 로고    scopus 로고
    • TCDD-Mediated Suppression of the in vitro Anti-Sheep Erythrocyte IgM Antibody Forming Cell Response is Reversed by Interferon Gamma
    • 10.1093/toxsci/kfn223, 2638643, 18948302
    • North CM, Kim BS, Snyder N, Crawford RB, Holsapple MP, Kaminski NE. TCDD-Mediated Suppression of the in vitro Anti-Sheep Erythrocyte IgM Antibody Forming Cell Response is Reversed by Interferon Gamma. Toxicol Sci 2009, 107:85-92. 10.1093/toxsci/kfn223, 2638643, 18948302.
    • (2009) Toxicol Sci , vol.107 , pp. 85-92
    • North, C.M.1    Kim, B.S.2    Snyder, N.3    Crawford, R.B.4    Holsapple, M.P.5    Kaminski, N.E.6
  • 68
    • 47949125190 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated impairment of B cell differentiation involves dysregulation of paired box 5 (Pax5) isoform, Pax5a
    • 10.1124/jpet.108.139857, 2562000, 18483191
    • Schneider D, Manzan MA, Crawford RB, Chen W, Kaminski NE. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated impairment of B cell differentiation involves dysregulation of paired box 5 (Pax5) isoform, Pax5a. J Pharmacol Exp Ther 2008, 326:463-474. 10.1124/jpet.108.139857, 2562000, 18483191.
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 463-474
    • Schneider, D.1    Manzan, M.A.2    Crawford, R.B.3    Chen, W.4    Kaminski, N.E.5
  • 69
    • 0141841784 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the regulation and posttranslational modification of p27kip1 in lipopolysaccharide-activated B cells
    • 10.1093/toxsci/kfg199, 12883080
    • Crawford RB, Sulentic CE, Yoo BS, Kaminski NE. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the regulation and posttranslational modification of p27kip1 in lipopolysaccharide-activated B cells. Toxicol Sci 2003, 75:333-342. 10.1093/toxsci/kfg199, 12883080.
    • (2003) Toxicol Sci , vol.75 , pp. 333-342
    • Crawford, R.B.1    Sulentic, C.E.2    Yoo, B.S.3    Kaminski, N.E.4
  • 70
    • 49549102185 scopus 로고    scopus 로고
    • Uncovering mechanisms of bistability in biological systems
    • 10.1016/j.copbio.2008.06.009, 18634875
    • Pomerening JR. Uncovering mechanisms of bistability in biological systems. Curr Opin Biotechnol 2008, 19:381-388. 10.1016/j.copbio.2008.06.009, 18634875.
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 381-388
    • Pomerening, J.R.1
  • 71
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability
    • 10.1016/S0955-0674(02)00314-9, 11891111
    • Ferrell JE. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol 2002, 14:140-148. 10.1016/S0955-0674(02)00314-9, 11891111.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 140-148
    • Ferrell, J.E.1
  • 72
    • 0345359924 scopus 로고    scopus 로고
    • A positive-feedback-based bistable 'memory module' that governs a cell fate decision
    • 10.1038/nature02089, 14647386
    • Xiong W, Ferrell JE. A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 2003, 426:460-465. 10.1038/nature02089, 14647386.
    • (2003) Nature , vol.426 , pp. 460-465
    • Xiong, W.1    Ferrell, J.E.2
  • 73
    • 40749085952 scopus 로고    scopus 로고
    • Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses
    • 10.1016/j.cub.2008.02.035, 2832910, 18364225
    • Ferrell JE. Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses. Curr Biol 2008, 18:R244-245. 10.1016/j.cub.2008.02.035, 2832910, 18364225.
    • (2008) Curr Biol , vol.18
    • Ferrell, J.E.1
  • 74
    • 50349087322 scopus 로고    scopus 로고
    • Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch
    • 10.1529/biophysj.107.120600, 2483757, 18469073
    • Palani S, Sarkar CA. Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophys J 2008, 95:1575-1589. 10.1529/biophysj.107.120600, 2483757, 18469073.
    • (2008) Biophys J , vol.95 , pp. 1575-1589
    • Palani, S.1    Sarkar, C.A.2
  • 75
    • 3042761223 scopus 로고    scopus 로고
    • Modelling the fission yeast cell cycle
    • 10.1093/bfgp/2.4.298, 15163365
    • Sveiczer A, Tyson JJ, Novak B. Modelling the fission yeast cell cycle. Brief Funct Genomic Proteomic 2004, 2:298-307. 10.1093/bfgp/2.4.298, 15163365.
    • (2004) Brief Funct Genomic Proteomic , vol.2 , pp. 298-307
    • Sveiczer, A.1    Tyson, J.J.2    Novak, B.3
  • 76
    • 38349013623 scopus 로고    scopus 로고
    • Coupled feedback loops form dynamic motifs of cellular networks
    • 10.1529/biophysj.107.105106, 2157222, 17951298
    • Kim JR, Yoon Y, Cho KH. Coupled feedback loops form dynamic motifs of cellular networks. Biophys J 2008, 94:359-365. 10.1529/biophysj.107.105106, 2157222, 17951298.
    • (2008) Biophys J , vol.94 , pp. 359-365
    • Kim, J.R.1    Yoon, Y.2    Cho, K.H.3
  • 77
    • 33645033645 scopus 로고    scopus 로고
    • Probing gene expression in live cells, one protein molecule at a time
    • 10.1126/science.1119623, 16543458
    • Yu J, Xiao J, Ren X, Lao K, Xie XS. Probing gene expression in live cells, one protein molecule at a time. Science 2006, 311:1600-1603. 10.1126/science.1119623, 16543458.
    • (2006) Science , vol.311 , pp. 1600-1603
    • Yu, J.1    Xiao, J.2    Ren, X.3    Lao, K.4    Xie, X.S.5
  • 78
    • 33645027986 scopus 로고    scopus 로고
    • Stochastic protein expression in individual cells at the single molecule level
    • 10.1038/nature04599, 16541077
    • Cai L, Friedman N, Xie XS. Stochastic protein expression in individual cells at the single molecule level. Nature 2006, 440:358-362. 10.1038/nature04599, 16541077.
    • (2006) Nature , vol.440 , pp. 358-362
    • Cai, L.1    Friedman, N.2    Xie, X.S.3
  • 79
    • 33748994704 scopus 로고    scopus 로고
    • Stochastic mRNA synthesis in mammalian cells
    • 10.1371/journal.pbio.0040309, 1563489,1563489, 17048983
    • Raj A, Peskin CS, Tranchina D, Vargas DY, Tyagi S. Stochastic mRNA synthesis in mammalian cells. PLoS Biol 2006, 4:e309. 10.1371/journal.pbio.0040309, 1563489,1563489, 17048983.
    • (2006) PLoS Biol , vol.4
    • Raj, A.1    Peskin, C.S.2    Tranchina, D.3    Vargas, D.Y.4    Tyagi, S.5
  • 80
    • 28944434119 scopus 로고    scopus 로고
    • Real-time kinetics of gene activity in individual bacteria
    • 10.1016/j.cell.2005.09.031, 16360033
    • Golding I, Paulsson J, Zawilski SM, Cox EC. Real-time kinetics of gene activity in individual bacteria. Cell 2005, 123:1025-1036. 10.1016/j.cell.2005.09.031, 16360033.
    • (2005) Cell , vol.123 , pp. 1025-1036
    • Golding, I.1    Paulsson, J.2    Zawilski, S.M.3    Cox, E.C.4
  • 81
    • 17444429245 scopus 로고    scopus 로고
    • Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors
    • Tumang JR, Frances R, Yeo SG, Rothstein TL. Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors. J Immunol 2005, 174:3173-3177.
    • (2005) J Immunol , vol.174 , pp. 3173-3177
    • Tumang, J.R.1    Frances, R.2    Yeo, S.G.3    Rothstein, T.L.4
  • 82
    • 2142653082 scopus 로고    scopus 로고
    • The sonic hedgehog signaling system as a bistable genetic switch
    • 10.1016/S0006-3495(04)74328-3, 1304145, 15111393
    • Lai K, Robertson MJ, Schaffer DV. The sonic hedgehog signaling system as a bistable genetic switch. Biophys J 2004, 86:2748-2757. 10.1016/S0006-3495(04)74328-3, 1304145, 15111393.
    • (2004) Biophys J , vol.86 , pp. 2748-2757
    • Lai, K.1    Robertson, M.J.2    Schaffer, D.V.3
  • 83
    • 77953992890 scopus 로고    scopus 로고
    • The Role of Core Biological Motifs in Dose-Response Modeling: An Example with Switch-Like Circuits
    • Hoboken, New Jersey: John Wiley & Sons, Young D, Michelson S,
    • Bhattacharya S, Zhang Q, Andersen ME. The Role of Core Biological Motifs in Dose-Response Modeling: An Example with Switch-Like Circuits. Systems Biology in Drug Discovery and Development 2009, Hoboken, New Jersey: John Wiley & Sons, Young D, Michelson S, .
    • (2009) Systems Biology in Drug Discovery and Development
    • Bhattacharya, S.1    Zhang, Q.2    Andersen, M.E.3
  • 84
    • 41749107942 scopus 로고    scopus 로고
    • Stochasticity and cell fate
    • 10.1126/science.1147888, 2605794, 18388284
    • Losick R, Desplan C. Stochasticity and cell fate. Science 2008, 320:65-68. 10.1126/science.1147888, 2605794, 18388284.
    • (2008) Science , vol.320 , pp. 65-68
    • Losick, R.1    Desplan, C.2
  • 85
    • 44349162752 scopus 로고    scopus 로고
    • Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
    • 10.1038/nature06965, 18497826
    • Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 2008, 453:544-547. 10.1038/nature06965, 18497826.
    • (2008) Nature , vol.453 , pp. 544-547
    • Chang, H.H.1    Hemberg, M.2    Barahona, M.3    Ingber, D.E.4    Huang, S.5
  • 86
    • 22744441386 scopus 로고    scopus 로고
    • Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
    • 10.1016/j.cell.2005.06.006, 16051143
    • Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell 2005, 122:169-182. 10.1016/j.cell.2005.06.006, 16051143.
    • (2005) Cell , vol.122 , pp. 169-182
    • Weinberger, L.S.1    Burnett, J.C.2    Toettcher, J.E.3    Arkin, A.P.4    Schaffer, D.V.5
  • 87
    • 34047118521 scopus 로고    scopus 로고
    • Tunability and noise dependence in differentiation dynamics
    • 10.1126/science.1137455, 17379809
    • Suel GM, Kulkarni RP, Dworkin J, Garcia-Ojalvo J, Elowitz MB. Tunability and noise dependence in differentiation dynamics. Science 2007, 315:1716-1719. 10.1126/science.1137455, 17379809.
    • (2007) Science , vol.315 , pp. 1716-1719
    • Suel, G.M.1    Kulkarni, R.P.2    Dworkin, J.3    Garcia-Ojalvo, J.4    Elowitz, M.B.5
  • 88
    • 0034496269 scopus 로고    scopus 로고
    • A true threshold dose in chemical carcinogenesis cannot be defined for a population, irrespective of the mode of action
    • discussion 571-562, 10.1191/096032700701546488, 11211995
    • Lutz WK. A true threshold dose in chemical carcinogenesis cannot be defined for a population, irrespective of the mode of action. Hum Exp Toxicol 2000, 19:566-568. discussion 571-562, 10.1191/096032700701546488, 11211995.
    • (2000) Hum Exp Toxicol , vol.19 , pp. 566-568
    • Lutz, W.K.1
  • 89
    • 1842405362 scopus 로고    scopus 로고
    • Lifetime of plasma cells in the bone marrow
    • 10.1038/40540, 9217150
    • Manz RA, Thiel A, Radbruch A. Lifetime of plasma cells in the bone marrow. Nature 1997, 388:133-134. 10.1038/40540, 9217150.
    • (1997) Nature , vol.388 , pp. 133-134
    • Manz, R.A.1    Thiel, A.2    Radbruch, A.3
  • 90
    • 42449099593 scopus 로고    scopus 로고
    • Maintenance of the plasma cell pool is independent of memory B cells
    • 10.1073/pnas.0800555105, 2290811, 18339801
    • Ahuja A, Anderson SM, Khalil A, Shlomchik MJ. Maintenance of the plasma cell pool is independent of memory B cells. Proc Natl Acad Sci USA 2008, 105:4802-4807. 10.1073/pnas.0800555105, 2290811, 18339801.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4802-4807
    • Ahuja, A.1    Anderson, S.M.2    Khalil, A.3    Shlomchik, M.J.4
  • 92
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • 10.1016/j.cell.2007.11.019, 18035408
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872. 10.1016/j.cell.2007.11.019, 18035408.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 96
    • 38049069841 scopus 로고    scopus 로고
    • B-cell identity--commitment is not forever
    • 10.1056/NEJMcibr0707112, 18172181
    • Nutt SL. B-cell identity--commitment is not forever. N Engl J Med 2008, 358:82-83. 10.1056/NEJMcibr0707112, 18172181.
    • (2008) N Engl J Med , vol.358 , pp. 82-83
    • Nutt, S.L.1
  • 97
    • 38549147656 scopus 로고    scopus 로고
    • Evolving views on the genealogy of B cells
    • 10.1038/nri2234, 18204470
    • Welner RS, Pelayo R, Kincade PW. Evolving views on the genealogy of B cells. Nat Rev Immunol 2008, 8:95-106. 10.1038/nri2234, 18204470.
    • (2008) Nat Rev Immunol , vol.8 , pp. 95-106
    • Welner, R.S.1    Pelayo, R.2    Kincade, P.W.3
  • 98
    • 2542455620 scopus 로고    scopus 로고
    • Stepwise reprogramming of B cells into macrophages
    • 10.1016/S0092-8674(04)00419-2, 15163413
    • Xie H, Ye M, Feng R, Graf T. Stepwise reprogramming of B cells into macrophages. Cell 2004, 117:663-676. 10.1016/S0092-8674(04)00419-2, 15163413.
    • (2004) Cell , vol.117 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 99
    • 34848853915 scopus 로고    scopus 로고
    • Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors
    • 10.1038/nature06159, 17851532
    • Cobaleda C, Jochum W, Busslinger M. Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature 2007, 449:473-477. 10.1038/nature06159, 17851532.
    • (2007) Nature , vol.449 , pp. 473-477
    • Cobaleda, C.1    Jochum, W.2    Busslinger, M.3
  • 100
    • 5344280456 scopus 로고    scopus 로고
    • MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation
    • 10.1016/j.cell.2004.09.014, 15454082
    • Fujita N, Jaye DL, Geigerman C, Akyildiz A, Mooney MR, Boss JM, Wade PA. MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell 2004, 119:75-86. 10.1016/j.cell.2004.09.014, 15454082.
    • (2004) Cell , vol.119 , pp. 75-86
    • Fujita, N.1    Jaye, D.L.2    Geigerman, C.3    Akyildiz, A.4    Mooney, M.R.5    Boss, J.M.6    Wade, P.A.7
  • 101
    • 33645053774 scopus 로고    scopus 로고
    • Mad1 is a transcriptional repressor of Bcl-6
    • 10.1016/j.molimm.2005.11.017, 16423395
    • Lee SC, Bottaro A, Chen L, Insel RA. Mad1 is a transcriptional repressor of Bcl-6. Mol Immunol 2006, 43:1965-1971. 10.1016/j.molimm.2005.11.017, 16423395.
    • (2006) Mol Immunol , vol.43 , pp. 1965-1971
    • Lee, S.C.1    Bottaro, A.2    Chen, L.3    Insel, R.A.4
  • 103
    • 33747133955 scopus 로고    scopus 로고
    • Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
    • 10.1016/j.immuni.2006.07.009, 16919487
    • Sciammas R, Shaffer AL, Schatz JH, Zhao H, Staudt LM, Singh H. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 2006, 25:225-236. 10.1016/j.immuni.2006.07.009, 16919487.
    • (2006) Immunity , vol.25 , pp. 225-236
    • Sciammas, R.1    Shaffer, A.L.2    Schatz, J.H.3    Zhao, H.4    Staudt, L.M.5    Singh, H.6
  • 104
    • 59149097949 scopus 로고    scopus 로고
    • Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor
    • 10.1016/j.bcp.2008.09.016, 2701375, 18848529
    • Hahn ME, Allan LL, Sherr DH. Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor. Biochem Pharmacol 2009, 77:485-497. 10.1016/j.bcp.2008.09.016, 2701375, 18848529.
    • (2009) Biochem Pharmacol , vol.77 , pp. 485-497
    • Hahn, M.E.1    Allan, L.L.2    Sherr, D.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.