Regulation of noise in the expression of a single gene

Nature Genetics

Volumn 31, Issue 1, 2002, Pages 69-73

  Ozbudak, Ertugrul M ^a   Thattai, Mukund ^a   Kurtser, Iren ^a   Grossman, Alan D ^a   Van Oudenaarden, Alexander ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACILLUS SUBTILIS; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; NOISE; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; REPORTER GENE; RNA TRANSLATION; STOCHASTIC MODEL;

BACILLUS SUBTILIS; ESCHERICHIA COLI; GENE EXPRESSION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MODELS, GENETIC; PHENOTYPE; POINT MUTATION; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; STOCHASTIC PROCESSES; TRANSCRIPTION, GENETIC;

BACILLUS SUBTILIS; POSIBACTERIA;

EID: 0036578645     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng869     Document Type: Article

References (28)

1. Exact stochastic simulation of coupled chemical reactions
2. It's a noisy business! Genetic regulation at the nanomolar scale
3. Stochastic mechanisms in gene expression
4. Stochastic kinetic analysis of developmental pathway bifurcation in phage λ-infected Escherichia coli cells
5. A synthetic oscillatory network of transcriptional regulators
6. Biological rhythms: Circadian clocks limited by noise
7. Fluctuations and quality of control in biological cells: Zero-order ultrasensitivity reinvestigated
8. From specific gene regulation to genomic networks: A global analysis of transcriptional regulation in Escherichia coli
9. 2 regulatory elements
10. Distribution of minichromosomes in individual Escherichia coli cells: Implications for replication control
11. The influence of ribosome-binding-site elements on translational efficiency in Bacillus subtilis and Escherichia coli in vivo
12. Intrinsic noise in gene regulatory networks
13. Stochastic focusing: Fluctuation-enhanced sensitivity of intracellular regulation
14. The segment polarity network is a robust developmental module
15. Engineering stability in gene networks by autoregulation
16. Expression of malT, the regulator gene of the maltose regulon in Escherichia coli, is limited both at transcription and translation
17. Comparative analysis of the cya locus in enterobacteria and related Gram-negative facultative anaerobes
18. Cyclic AMP in prokaryotes
19. Non-genetic individuality: Chance in the single cell
20. Origins of individual swimming behavior in bacteria
21. Autoregulation and function of a repressor in bacteriophage λ
22. Toward in vivo digital circuits
23. Computational studies of gene regulatory networks: In numero molecular biology
24. Construction of a genetic toggle switch in Escherichia coli
25. Stochasticity in transcriptional regulation: Origins, consequences and mathematical representations
26. How to achieve constitutive expression of a gene within an inducible operon: The example of the nagC gene of Escherichia coli
27. Lack of a 5′ non-coding region in Tn1721 encoded tetR mRNA is associated with a low efficiency of translation and a short half-life in Escherichia coli
28. trp aporepressor production is controlled by autogenous regulation and inefficient translation