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Volumn 12, Issue 13, 1998, Pages 1953-1961

Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor

Author keywords

BCL 6; BCR signaling; MAP kinase; POZ zinc finger proteins; Ubiquitin proteasome

Indexed keywords

DNA; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEASOME; RNA; TRANSCRIPTION FACTOR; UBIQUITIN; ZINC FINGER PROTEIN;

EID: 0032128002     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.13.1953     Document Type: Article
Times cited : (256)

References (57)
  • 1
    • 0029099016 scopus 로고
    • The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins
    • Albagli, O., P. Dhordain, C. Deweindt, G. Lecocq, and D. Leprince. 1995. The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins. Cell Growth & Differ. 6: 1193-1198.
    • (1995) Cell Growth & Differ. , vol.6 , pp. 1193-1198
    • Albagli, O.1    Dhordain, P.2    Deweindt, C.3    Lecocq, G.4    Leprince, D.5
  • 4
    • 9244234507 scopus 로고    scopus 로고
    • The SV40 large T antigen and adenovirus E1A oncoproteins interact with distinct isoforms of the transcriptional co-activator p300
    • Avantaggiati, M., M. Carbone, A. Graessman, Y. Nakatani, B. Howard, and A. Levine. 1996. The SV40 large T antigen and adenovirus E1A oncoproteins interact with distinct isoforms of the transcriptional co-activator p300. EMBO J. 15: 2236-2248.
    • (1996) EMBO J. , vol.15 , pp. 2236-2248
    • Avantaggiati, M.1    Carbone, M.2    Graessman, A.3    Nakatani, Y.4    Howard, B.5    Levine, A.6
  • 5
    • 0028040875 scopus 로고
    • The POZ domain: A conserved protein-protein interaction motif
    • Bardwell, V.J. and R. Treisman. 1994. The POZ domain: A conserved protein-protein interaction motif. Genes & Dev. 8: 1664-1677.
    • (1994) Genes & Dev. , vol.8 , pp. 1664-1677
    • Bardwell, V.J.1    Treisman, R.2
  • 6
    • 0027288335 scopus 로고
    • Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas
    • Baron, B.W., G. Nucifora, N. McCabe, R. Espinosa, B.M. Le, and T.W. McKeithan. 1993. Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas. Proc Natl. Acad. Sci. 90: 5262-5266.
    • (1993) Proc Natl. Acad. Sci. , vol.90 , pp. 5262-5266
    • Baron, B.W.1    Nucifora, G.2    McCabe, N.3    Espinosa, R.4    Le, B.M.5    McKeithan, T.W.6
  • 7
    • 0028331006 scopus 로고
    • LAZ3 rearrangements in non-Hodgkin's lymphoma: Correlation with histology, immunophenotype, karyotype, and clinical outcome in 217 patients
    • Bastard, C., C. Deweindt, J.P. Kerckaert, B. Lenormand, A. Rossi, F. Pezzella, C. Fruchart, C. Duval, M. Monconduit, and H. Tilly. 1994. LAZ3 rearrangements in non-Hodgkin's lymphoma: Correlation with histology, immunophenotype, karyotype, and clinical outcome in 217 patients. Blood 83: 2423-2427.
    • (1994) Blood , vol.83 , pp. 2423-2427
    • Bastard, C.1    Deweindt, C.2    Kerckaert, J.P.3    Lenormand, B.4    Rossi, A.5    Pezzella, F.6    Fruchart, C.7    Duval, C.8    Monconduit, M.9    Tilly, H.10
  • 8
    • 0030954572 scopus 로고    scopus 로고
    • Positive and negative signal co-operativity in the immune system: The BCR, Fc gamma RIIB, CR2 paradigm
    • Cambier, J.C. 1997. Positive and negative signal co-operativity in the immune system: The BCR, Fc gamma RIIB, CR2 paradigm Biochem. Soc. Trans. 25: 441-445.
    • (1997) Biochem. Soc. Trans. , vol.25 , pp. 441-445
    • Cambier, J.C.1
  • 10
    • 0003236545 scopus 로고    scopus 로고
    • Downregulation of BCL-6 gene expression by CD40 and EBV latent membrane protein-1 (LMP1) and its block in lymphoma carrying BCL-6 rearrangements
    • Cattoretti, G., J. Zhang, A.M. Cleary, S. Lederman, G. Gaidano, A. Carbone, R.S.K. Chaganti, and R. Dalla-Favera. 1997. Downregulation of BCL-6 gene expression by CD40 and EBV latent membrane protein-1 (LMP1) and its block in lymphoma carrying BCL-6 rearrangements. (Suppl. I) Blood 90: p175a.
    • (1997) Blood , vol.90 , Issue.1 SUPPL.
    • Cattoretti, G.1    Zhang, J.2    Cleary, A.M.3    Lederman, S.4    Gaidano, G.5    Carbone, A.6    Chaganti, R.S.K.7    Dalla-Favera, R.8
  • 11
    • 0029902260 scopus 로고    scopus 로고
    • BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor
    • Chang, C.C., B.H. Ye, R.S. Chaganti, and R. Dalla-Favera. 1996. BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor. Proc. Natl. Acad. Sci. 93: 6947-6952.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 6947-6952
    • Chang, C.C.1    Ye, B.H.2    Chaganti, R.S.3    Dalla-Favera, R.4
  • 12
    • 0025853152 scopus 로고
    • The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers
    • Chardin, P., G. Courtois, M.G. Mattei, and S. Gisselbrecht. 1991. The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers. Nucleic Acids Res. 19: 1431-1436.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1431-1436
    • Chardin, P.1    Courtois, G.2    Mattei, M.G.3    Gisselbrecht, S.4
  • 13
    • 0027411688 scopus 로고
    • Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia
    • Chen, Z., N.J. Brand, A. Chen, S.J. Chen, J.H. Tong, Z.Y. Wang, S. Waxman, and A. Zelent. 1993. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J. 12: 1161-1167.
    • (1993) EMBO J. , vol.12 , pp. 1161-1167
    • Chen, Z.1    Brand, N.J.2    Chen, A.3    Chen, S.J.4    Tong, J.H.5    Wang, Z.Y.6    Waxman, S.7    Zelent, A.8
  • 14
    • 0028179425 scopus 로고
    • PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors
    • Chen, Z., F. Guidez, P. Rousselot, A. Agadir, S.J. Chen, Z.Y. Wang, L. Degos, A. Zelent, S. Waxman, and C. Chomienne. 1994. PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors. Proc. Natl. Acad. Sci. 91: 1178-1182.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 1178-1182
    • Chen, Z.1    Guidez, F.2    Rousselot, P.3    Agadir, A.4    Chen, S.J.5    Wang, Z.Y.6    Degos, L.7    Zelent, A.8    Waxman, S.9    Chomienne, C.10
  • 15
    • 0031962523 scopus 로고    scopus 로고
    • Heterologous promoters fused to BCL-6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation
    • Chen, W., S. Iida, D.C. Louie, R. Dalla-Favera, and R.S.K. Chaganti. 1998. Heterologous promoters fused to BCL-6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation. Blood 91: 603-607.
    • (1998) Blood , vol.91 , pp. 603-607
    • Chen, W.1    Iida, S.2    Louie, D.C.3    Dalla-Favera, R.4    Chaganti, R.S.K.5
  • 17
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent, A.L., A.L. Shaffer, X. Yu, D. Allman, and L.M. Staudt. 1997. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 276: 589-592.
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 18
    • 0028822226 scopus 로고
    • The LAZ3/ BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: A novel function for the BTB/POZ domain as an autonomous repressing domain
    • Deweindt, C., O. Albagli, F. Bernardin, P. Dhordain, S. Quief, D. Lantoine, J.P. Kerckaert, and D. Leprince. 1995. The LAZ3/ BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: A novel function for the BTB/POZ domain as an autonomous repressing domain. Cell Growth & Differ. 6: 1495-1503.
    • (1995) Cell Growth & Differ. , vol.6 , pp. 1495-1503
    • Deweindt, C.1    Albagli, O.2    Bernardin, F.3    Dhordain, P.4    Quief, S.5    Lantoine, D.6    Kerckaert, J.P.7    Leprince, D.8
  • 19
    • 0025955580 scopus 로고
    • The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers
    • DiBello, P.R., D.A. Withers, C.A. Bayer, J.W. Fristrom, and G.M. Guild. 1991. The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers. Genetics 129: 385-397.
    • (1991) Genetics , vol.129 , pp. 385-397
    • DiBello, P.R.1    Withers, D.A.2    Bayer, C.A.3    Fristrom, J.W.4    Guild, G.M.5
  • 21
    • 0028171255 scopus 로고
    • Differential expression of Broad-Complex transcription factors may forecast tissue-specific developmental fates during Drosophila metamorphosis
    • Emery, I.F., V. Bedian, and G.M. Guild. 1994. Differential expression of Broad-Complex transcription factors may forecast tissue-specific developmental fates during Drosophila metamorphosis. Development 120: 3275-3287.
    • (1994) Development , vol.120 , pp. 3275-3287
    • Emery, I.F.1    Bedian, V.2    Guild, G.M.3
  • 22
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • Fukada T., M. Hibi, Y. Yamanaka, M. Takahashi-Tezuka, Y. Fujitani, T. Yamaguchi, K. Nakajima, and T. Hirano. 1996. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis. Immunity 5: 449-460.
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3    Takahashi-Tezuka, M.4    Fujitani, Y.5    Yamaguchi, T.6    Nakajima, K.7    Hirano, T.8
  • 24
    • 0028931028 scopus 로고
    • Signal transduction by the antigen receptors of B and T lymphocytes
    • Gold, M.R. and L. Matsuuchi. 1995. Signal transduction by the antigen receptors of B and T lymphocytes. Int. Rev. Cytol. 157: 181-276.
    • (1995) Int. Rev. Cytol. , vol.157 , pp. 181-276
    • Gold, M.R.1    Matsuuchi, L.2
  • 25
    • 0026787281 scopus 로고
    • Selective activation of p42 mitogen-activated protein (MAP) kinase in murine B lymphoma cell lines by membrane immunoglobulin cross-linking. Evidence for protein kinase C-independent and -dependent mechanisms of activation
    • Gold, M.R., J.S. Sanghera, J. Stewart, and S.L. Pelech. 1992. Selective activation of p42 mitogen-activated protein (MAP) kinase in murine B lymphoma cell lines by membrane immunoglobulin cross-linking. Evidence for protein kinase C-independent and -dependent mechanisms of activation. Biochem. J. 287: 269-276.
    • (1992) Biochem. J. , vol.287 , pp. 269-276
    • Gold, M.R.1    Sanghera, J.S.2    Stewart, J.3    Pelech, S.L.4
  • 26
    • 0025191061 scopus 로고
    • The Tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern
    • Harrison, S.D. and A.A. Travers. 1990. The Tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern. EMBO J. 9: 207-216.
    • (1990) EMBO J. , vol.9 , pp. 207-216
    • Harrison, S.D.1    Travers, A.A.2
  • 27
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 28
    • 0027306091 scopus 로고
    • LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas
    • Kerckaert, J.P., C. Deweindt, H. Tilly, S. Quief, G. Lecocq, and C. Bastard. 1993. LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas. Nature Genet. 5: 66-70.
    • (1993) Nature Genet. , vol.5 , pp. 66-70
    • Kerckaert, J.P.1    Deweindt, C.2    Tilly, H.3    Quief, S.4    Lecocq, G.5    Bastard, C.6
  • 29
    • 0000413462 scopus 로고    scopus 로고
    • Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway
    • Kim, T.K. and T. Maniatis. 1996. Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway. Science 273: 1717-1719.
    • (1996) Science , vol.273 , pp. 1717-1719
    • Kim, T.K.1    Maniatis, T.2
  • 30
    • 0026655315 scopus 로고
    • A family of DNA virus genes that consists of fused portions of unrelated cellular genes
    • Koonin, E.V., T.G. Senkevich, and V.I. Chernos. 1992. A family of DNA virus genes that consists of fused portions of unrelated cellular genes. Trends Biochem. Sci. 17: 213-214.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 213-214
    • Koonin, E.V.1    Senkevich, T.G.2    Chernos, V.I.3
  • 31
    • 0030790796 scopus 로고    scopus 로고
    • Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack
    • Li, S., Y. Li, R.W. Carthew, and Z.-C. Lai. 1997. Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack. Cell 90: 469-478.
    • (1997) Cell , vol.90 , pp. 469-478
    • Li, S.1    Li, Y.2    Carthew, R.W.3    Lai, Z.-C.4
  • 35
    • 0028031988 scopus 로고
    • Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein
    • Miki, T., N. Kawamata, S. Hirosawa, and N. Aoki. 1994. Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein. Blood 83: 26-32.
    • (1994) Blood , vol.83 , pp. 26-32
    • Miki, T.1    Kawamata, N.2    Hirosawa, S.3    Aoki, N.4
  • 36
    • 0028357667 scopus 로고
    • Signal transduction mediated by the reconstituted IL-2 receptor. Evidence for a cell type-specific function of IL-2 receptor beta-chain
    • Minami, Y., I. Oishi, Z.J. Liu, S. Nakagawa, T. Miyazaki, and T. Taniguchi. 1994. Signal transduction mediated by the reconstituted IL-2 receptor. Evidence for a cell type-specific function of IL-2 receptor beta-chain. J. Immunol. 152: 5680-5690.
    • (1994) J. Immunol. , vol.152 , pp. 5680-5690
    • Minami, Y.1    Oishi, I.2    Liu, Z.J.3    Nakagawa, S.4    Miyazaki, T.5    Taniguchi, T.6
  • 37
    • 0030984830 scopus 로고    scopus 로고
    • BCL-6 is phosphorylated at multiple sites in its serine-and proline-clustered region by mitogen-activated protein kinase (MAPK) in vivo
    • Moriyama, M., T. Yamochi, K. Semba, T. Akiyama, and S. Mori. 1997. BCL-6 is phosphorylated at multiple sites in its serine-and proline-clustered region by mitogen-activated protein kinase (MAPK) in vivo. Oncogens 14: 2465-2474.
    • (1997) Oncogens , vol.14 , pp. 2465-2474
    • Moriyama, M.1    Yamochi, T.2    Semba, K.3    Akiyama, T.4    Mori, S.5
  • 38
    • 0029019660 scopus 로고
    • BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts
    • Onizuka, T., M. Moriyama, T. Yamochi, T. Kuroda, A. Kazama, N. Kanazawa, K. Sato, T. Kato, H. Ota, and S. Mori. 1995. BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts. Blood 86: 28-37.
    • (1995) Blood , vol.86 , pp. 28-37
    • Onizuka, T.1    Moriyama, M.2    Yamochi, T.3    Kuroda, T.4    Kazama, A.5    Kanazawa, N.6    Sato, K.7    Kato, T.8    Ota, H.9    Mori, S.10
  • 39
    • 0029024622 scopus 로고
    • Analysis of LAZ3 (BCL-6) status in B-cell non-Hodgkin's lymphomas: Results of rearrangement and gene expression studies and a mutational analysis of coding region sequences
    • Otsuki, T., T. Yano, H.M. Clark, C. Bastard, J.P. Kerckaert, E.S. Jafre, and M. Raffeld. 1995. Analysis of LAZ3 (BCL-6) status in B-cell non-Hodgkin's lymphomas: Results of rearrangement and gene expression studies and a mutational analysis of coding region sequences. Blood 85: 2877-2884.
    • (1995) Blood , vol.85 , pp. 2877-2884
    • Otsuki, T.1    Yano, T.2    Clark, H.M.3    Bastard, C.4    Kerckaert, J.P.5    Jafre, E.S.6    Raffeld, M.7
  • 41
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
    • Palombella, V.J., O.J. Rando, A.L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell 78: 773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 42
    • 0029034774 scopus 로고
    • Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
    • Pang, L., T. Sawada, S.J. Decker, and A.R. Saltiel. 1995. Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J. Biol. Chem. 270: 13585-13588.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13585-13588
    • Pang, L.1    Sawada, T.2    Decker, S.J.3    Saltiel, A.R.4
  • 43
    • 0030200110 scopus 로고    scopus 로고
    • PEST sequences and regulation by proteolysis
    • Rechsteiner, M. and S.W. Rogers. 1996. PEST sequences and regulation by proteolysis. Trends Biochem. Sci. 21: 267-271.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 267-271
    • Rechsteiner, M.1    Rogers, S.W.2
  • 44
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock, K.L., C. Gramm, L. Rothstein, K. Clark, R. Stein, L. Dick, D. Hwang, and A.L. Goldberg. 1994. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6    Hwang, D.7    Goldberg, A.L.8
  • 45
    • 0022971952 scopus 로고
    • Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
    • Rogers, S., R. Wells, and M. Rechsteiner. 1986. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis. Science 234: 364-368.
    • (1986) Science , vol.234 , pp. 364-368
    • Rogers, S.1    Wells, R.2    Rechsteiner, M.3
  • 46
    • 0029620212 scopus 로고
    • Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells
    • Sakata, N., H.R. Patel, N. Terada, A. Aruffo, G.L. Johnson, and E.W. Gelfand. 1995. Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells. J. Biol. Chem. 270: 30823-30828.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30823-30828
    • Sakata, N.1    Patel, H.R.2    Terada, N.3    Aruffo, A.4    Johnson, G.L.5    Gelfand, E.W.6
  • 47
    • 0029899571 scopus 로고    scopus 로고
    • Transcriptional repression by the proto-oncogene BCL-6
    • Seyfert, V.L., D. Allman, Y. He, and L.M. Staudt. 1996. Transcriptional repression by the proto-oncogene BCL-6. Oncogene 12: 2331-2342.
    • (1996) Oncogene , vol.12 , pp. 2331-2342
    • Seyfert, V.L.1    Allman, D.2    He, Y.3    Staudt, L.M.4
  • 48
    • 0030587829 scopus 로고    scopus 로고
    • Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor
    • Sutherland, C.L., A.W. Heath, S.L. Pelech, P.R. Young, and M.R. Gold. 1996. Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor. J. Immunol. 157: 3381-3390.
    • (1996) J. Immunol. , vol.157 , pp. 3381-3390
    • Sutherland, C.L.1    Heath, A.W.2    Pelech, S.L.3    Young, P.R.4    Gold, M.R.5
  • 49
    • 0030849728 scopus 로고    scopus 로고
    • PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism
    • Tang, A.H., T.P. Neufeld, E. Kwan, and M. Rubin. 1997. PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell 90: 459-467.
    • (1997) Cell , vol.90 , pp. 459-467
    • Tang, A.H.1    Neufeld, T.P.2    Kwan, E.3    Rubin, M.4
  • 50
    • 0030993376 scopus 로고    scopus 로고
    • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    • Tedder, T.F., J. Tuscano, S. Sato, and J.H. Kehrl. 1997. CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu. Rev. Immunol. 15: 481-504.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 481-504
    • Tedder, T.F.1    Tuscano, J.2    Sato, S.3    Kehrl, J.H.4
  • 51
    • 0027209271 scopus 로고
    • Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts
    • Victor, I., P. Schwenger, W. Li, J. Schlessinger, and J. Vilcek. 1993. Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. J. Biol. Chem. 268: 18994-18999.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18994-18999
    • Victor, I.1    Schwenger, P.2    Li, W.3    Schlessinger, J.4    Vilcek, J.5
  • 52
    • 0027403024 scopus 로고
    • Kelch encodes a component of intercellular bridges in Drosophila egg chamber
    • Xue, F. and L. Cooley. 1993. Kelch encodes a component of intercellular bridges in Drosophila egg chamber. Cell 72: 681-693.
    • (1993) Cell , vol.72 , pp. 681-693
    • Xue, F.1    Cooley, L.2
  • 53
    • 0028308224 scopus 로고
    • Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase
    • Yan, M. and D.J. Templeton. 1994. Identification of 2 serine residues of MEK-1 that are differentially phosphorylated during activation by raf and MEK kinase. J. Biol. Chem. 269: 19067-19073.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19067-19073
    • Yan, M.1    Templeton, D.J.2
  • 55
    • 0029562068 scopus 로고
    • Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma
    • Ye, B.H., S. Chaganti, C.C. Chang, H. Niu, P. Corradini, R.S. Chaganti, and R. Dalla-Favera. 1995. Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. EMBO J. 14: 6209-6217.
    • (1995) EMBO J. , vol.14 , pp. 6209-6217
    • Ye, B.H.1    Chaganti, S.2    Chang, C.C.3    Niu, H.4    Corradini, P.5    Chaganti, R.S.6    Dalla-Favera, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.