Perspectives on tissue interactions in development and disease

Current Molecular Medicine

Volumn 10, Issue 1, 2010, Pages 95-112

  Strand, D W ^a   Franco, O E ^a   Basanta, D ^a   Anderson, A R A ^a   Hayward, S W ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Development; Disease; Epithelia; Models; Organ; Stroma; Tissue interaction

Indexed keywords

CARCINOGENESIS; CELL INTERACTION; COMPUTER MODEL; DEVELOPMENTAL BIOLOGY; EMPIRICISM; EPITHELIUM; HUMAN; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; MATHEMATICAL MODEL; MICROENVIRONMENT; MOLECULAR BIOLOGY; NONHUMAN; ORGANOGENESIS; REVIEW; STROMA; TISSUE REPAIR;

ANIMALS; CELL COMMUNICATION; EPITHELIAL CELLS; HUMANS; NEOPLASMS; STROMAL CELLS;

EID: 77949462461     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652410791065363     Document Type: Review

References (211)

1. Grobstein, C. (1953) J. Exp. Zool., 124, 383-444.
2. Grobstein, C. (1954) Tissue interactions in the morphogenesis of mouse embryonic rudiments in vitro. in Aspects of Synthesis and Order in Growth, D. Rudnick, Ed. Princeton University Press: Princeton, pp. 233-256.
3. Grobstein, C. (1967) J. Natl. Cancer Inst. Monogr., 26, 279-299.
4. Bernfield, M. and Banerjee, S.D. (1982) Dev. Biol., 90, 291-305.
5. Bernfield, M.R. and Banerjee, S.D. (1972) J. Cell Biol., 52, 664- 673.
6. Bernfield, M.R., Banerjee, S.D. and Cohn, R.H. (1972) J. Cell Biol., 52, 674-689.
7. Bernfield, M.R., Banerjee, S.D., Koda, J.E. and Rapraeger, A.C. (1984) Remodeling of the basement membrane as a mechanism of morphogenetic tissue interactions; in The Role of Extracellular Matrix in Development; Trelstad, R.L. Ed. A.R. Liss: New York, pp. 545-596.
8. Bernfield, M.R., Cohn, R.H. and Banerjee, S.D. (1973) Am. Zool., 13, 1067-1083.
9. Wessells, N.K. (1970) J. Exp. Zool., 175, 455-466.
10. Sakakura, T., Nishizuka, Y. and Dawe, C.J. (1976) Science, 194, 1439-1441.
11. Saxén, L. (1977) Directive versus permissive induction: a working hypothesis. In: Cell and Tissue Interactions; Burger, J.W.; Lash, M.M. Eds. Raven Press: New York, pp 1-10.
12. Thesleff, I., Vaahtokari, A. and Partanen, A.M. (1995) Int. J. Dev. Biol., 39, 35-50.
13. Spring, J., Yanze, N., Middel, A.M., Stierwald, M., Groger, H. and Schmid, V. (2000) Dev. Biol., 228, 363-375.
14. Hay, E.D. (2005) Dev. Dyn., 233, 706-720.
15. Pierce, G. and Wallace, C. (1971) Cancer Res., 31, 127-134.
16. McNeal, J.E. (1978) Invest. Urol., 15, 340-345.
17. Hogan, B.L. (1999) Cell, 96, 225- 233.
18. Hayward, S.W., Del Buono, R., Deshpande, N. and Hall, P.A. (1992) J. Cell Sci., 102, 361-372.
19. Risbridger, G.P., Wang, H., Frydenberg, M. and Cunha, G. (2001) Endocrinology, 142, 2443-2450.
20. Page-McCaw, A., Ewald, A.J. and Werb, Z. (2007) Nat. Rev. Mol. Cell Biol., 8, 221-233.
21. Risbridger, G.P., Almahbobi, G.A. and Taylor, R.A. (2005) Cell Tissue Res., 322, 173-181.
22. Salazar-Ciudad, I., Jernvall, J. and Newman, S.A. (2003) Development, 130, 2027-2037.
23. Wells, J.M. and Melton, D.A. (1999) Annu. Rev. Cell Dev. Biol., 15, 393-410.
24. Cano, A., Perez-Moreno, M.A., Rodrigo, I., Locascio, A., Blanco, M.J., del Barrio, M.G., Portillo, F. and Nieto, M.A. (2000) Nat. Cell Biol., 2, 76-83.
25. Haffen, K., Kedinger, M. and Simon-Assmann, P. (1987) J. Pediatr. Gastroenterol. Nutr., 6, 14-23.
26. Kedinger, M., Simon-Assmann, P.M., Grenier, J.F. and Haffen, K. (1981) Dev. Biol., 86, 339-347.
27. Yasugi, S. and Mizuno, T. (1974) Dev. Biol., 174, 107-116.
28. Grapin-Botton, A. and Melton, D.A. (2000) Trends Genet., 16, 124-130.
29. Le Douarin, N., Bussonnet, C. and Chaumont, F. (1968) Ann. Embryol. Morphol., 1, 29-39.
30. Yasugi, S. (1979) Dev. Growth Differ., 21, 343-348.
31. Yasugi, S. and Mizuno, T. (1978) Dev. Growth and Differ., 20, 261-267.
32. Thesleff, I. and Hurmerinta, K. (1981) Differentiation, 18, 75-88.
33. Kollar, E.J. (1970) J. Invest. Dermatol., 55, 374-378.
34. Kollar, E.J. and Baird, G.R. (1969) J. Embryol. Exp. Morphol., 21, 131-148.
35. Kollar, E.J. and Baird, G.R. (1970) J. Embryol. Exp. Morph., 24, 173-186.
36. Mina, M. and Kollar, E.J. (1987) Arch. Oral Biol., 32, 123-127.
37. Cunha, G.R. (1972) Anat. Rec., 172, 529-542.
38. Cunha, G.R. (1976) J. Exp. Zool., 196, 361-370.
39. Cunha, G.R. and Chung, L.W. (1981) J. Steroid Biochem., 14, 1317- 1324.
40. Chung, L.W. and Cunha, G.R. (1983) Prostate, 4(5), 503-511.
41. Cunha, G.R., Fujii, H., Neubauer, B.L., Shannon, J.M., Sawyer, L.M. and Reese, B.A. (1983) J. Cell Biol., 96, 1662-1670.
42. DiSandro, M.J., Li, Y., Baskin, L.S., Hayward, S. and Cunha, G. (1998) J. Urol., 160, 1040-1046; discussion 1079.
43. Cunha, G.R., Donjacour, A.A., Hayward, S.W., Grossfeld, G.D., Thomson, A.A., Marker, P.C. and Dahiya, R. (2002) Role of Stroma. In: Prostate Cancer; Carroll, P.R.; Grossfeld, G.D., Eds. BC Decker, Inc: Hamilton, pp. 60-81.
44. Buchanan, D.L., Setiawan, T., Lubahn, D.L., Taylor, J.A., Kurita, T., Cunha, G.R., and Cooke, P.S. (1998) Endocrinology, 140, 484-491.
45. Kurita, T., Wang, Y.Z., Donjacour, A.A., Zhao, C., Lydon, J.P., O'Malley, B.W., Isaacs, J.T., Dahiya, R. and Cunha, G.R. (2001) Cell Death Differ., 8, 192-200.
46. Adams, J.C. and Watt, F.M. (1993) Development, 117, 1183-1198.
47. Wicha, M.S., Liotta, L.A., Vonderhaar, B.K. and Kidwell, W.R. (1980) Dev. Biol., 80, 253-256.
48. Liotta, L., Rao, C. and Wewer, U. (1988) Annu. Rev. Biochem., 55, 1037-1057.
49. Banerjee, S.D., Cohn, R.H. and Bernfield, M.R. (1977) J. Cell Biol., 73, 445-463.
50. Smith, R.L. and Bernfield, M. (1982) Dev. Biol., 94, 378-390.
51. Simon-Assmann, P., Bouziges, F., Haffen, A.K. and Kedinger, M. (1988) Development, 102, 339-347.
52. Fata, J.E., Werb, Z. and Bissell, M.J. (2004) Breast Cancer Res., 6, 1-11.
53. De Arcangelis, A., Neuville, P., Boukamel, R., Lefebvre, O., Kedinger, M. and Simon-Assmann, P. (1996) J. Cell Biol., 133, 417-430.
54. Cunha, G.R. (1994) Cancer, 74, 1030-1044.
55. Pivonka, P., Zimak, J., Smith, D.W., Gardiner, B.S., Dunstan, C.R., Sims, N.A., John Martin, T. and Mundy, G.R. (2008) Bone, 43, 249- 263.
56. Medzhitov, R. (2008) Nature, 454, 428-435.
57. Desmouliere, A., Chaponnier, C. and Gabbiani. (2005) Wound Repair Regen., 13, 7-12.
58. Gabbiani, G., Ryan, G.B. and Majne, G. (1971) Experientia, 27, 549-50.
59. Gabbiani, G. (2003) J. Pathol., 200, 500-503.
60. Skalli, O., Ropraz, P., Trzeciak, A., Benzonana, G., Gillessen, D. and Gabbiani, G. (1986) J. Cell Biol., 103, 2787-2796.
61. Dvorak, H.F. (1986) N. Engl. J. Med., 315, 1650-1659.
62. Ronnov-Jessen, L., Petersen, O.W. and Bissell, M.J. (1996) Physiol. Rev., 76, 69-125.
63. Schor, S.L., Schor, A.M., Grey, A.M., and Rushton, G. (1988) J. Cell Sci., 90, 391-399.
64. Tlsty, T.D. and Coussens, L.M. (2006) Annu. Rev. Pathol., 1, 119-150.
65. Paszek, M.J., Zahir, N., Johnson, K.R., Lakins, J.N., Rozenberg, G.I., Gefen, A., Reinhart-King, C.A., Margulies, S.S., Dembo, M., Boettiger, D., Hammer, D.A. and Weaver, V.M. (2005) Cancer Cell, 8, 241-254.
66. Kass, L., Erler, J.T., Dembo, M. and Weaver, V.M. (2007) Int. J. Biochem. Cell Biol., 39, 1987-1994.
67. Chung, L.W. (1991) Cancer Metastasis Rev., 10, 263-274.
68. Tuxhorn, J.A., McAlhany, S.J., Dang, T.D., Ayala, G.E., and Rowley, D.R. (2002) Cancer Res., 62, 3298-307.
69. Tlsty, T.D. (2001) Semin. Cancer Biol., 11, 97-104.
70. Orimo, A., Gupta, P.B., Sgroi, D.C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V.J., A.L. Richardson, and Weinberg, R.A. (2005) Cell, 121, 335-348.
71. Hwang, R.F., Moore, T., Arumugam, T., Ramachandran, V., Amos, A. Rivera, K.D., Ji, B., Evans, D.B., and Logsdon, C.D. (2008) Cancer Res., 68, 918-926.
72. Olumi, A.F., Grossfeld, G.D., Hayward, S.W., Carroll, P.R., Tlsty, T.D., and Cunha, G.R. (1999) Cancer Res., 59, 5002-5011.
73. Mueller, M.M. and Fusenig, N.E. (2002) Differentiation, 70, 486-497.
74. Ohuchida, K., Mizumoto, K., Murakami, M., Qian, L.W., Sato, N., Nagai, E., Matsumoto, K., Nakamura, T. and Tanaka, M. (2004) Cancer Res., 64, 3215-3222.
75. Hayward, S.W., Wang, Y., Cao, M., Hom, Y.K., Zhang, B., Grossfeld, G.D., Sudilovsky, D. and Cunha, G.R. (2001) Cancer Res., 61, 8135-8142.
76. Phillips, J.L., Hayward, S.W., Wang, Y., Vasselli, J., Pavlovich, C., Padilla-Nash, H., Pezullo, J.R., Ghadimi, B.M., Grossfeld, G.D., Rivera, A., Linehan, W.M., Cunha, G.R. and Ried, T. (2001) Cancer Res., 61, 8143-8149.
77. Schor, S.L. and Schor, A.M. (1987) Exp. Cell Biol., 55, 11-17.
78. Schor, S.L. and Schor, A.M. (1987) BioEssays, 7, 200-204.
79. Schor, S.L., Schor, A.M. and Rushton, G. (1988) J. Cell Sci., 90, 401-407.
80. Hayward, S.W., Rosen, M.A. and Cunha, G.R. (1997) Br. J. Urol., 79, 18-26.
81. Tuxhorn, J.A., Ayala, G.E., Smith, M.J., Smith, V.C., Dang, T.D. and Rowley, D.R. (2002) Clin. Cancer Res., 8, 2912-2923.
82. Ayala, G., Tuxhorn, J.A., Wheeler, T.M., Frolov, A., Scardino, P.T., Ohori, M., Wheeler, M., Spitler, J. and Rowley, D.R. (2003) Clin. Cancer Res., 9, 4792-4801.
83. Sugimoto, H., Mundel, T.M., Kieran, M.W. and Kalluri, R. (2006) Cancer Biol. Ther., 5, 1640-1646.
84. Haviv, I., Polyak, K., Qiu, W., Hu, M. and Campbell, I. (2009) Cell Cycle, 8, 589-595.
85. Ostman, A. and Augsten, M. (2009) Curr. Opin. Genet. Dev., 19, 67-73.
86. Radisky, D.C., Kenny, P.A. and Bissell, M.J. (2007) J. Cell Biochem., 101(4), 830-839.
87. Abe, R., Donnelly, S.C., Peng, T., Bucala, R. and Metz, C.N. (2001) J. Immunol., 166, 7556-7562.
88. Karnoub, A.E., Dash, A.B., Vo, A.P., Sullivan, A., Brooks, M.W., Bell, G.W., Richardson, A.L., Polyak, K., Tubo, R. and Weinberg, R.A. (2007) Nature, 449, 557-63.
89. Weber, F., Xu, Y., Zhang, L., Patocs, A., Shen, L., Platzer, P. and Eng, C. (2007) JAMA, 297, 187-195.
90. Allinen, M., Beroukhim, R., Cai, L., Brennan, C., Lahti-Domenici, J., Huang, H., Porter, D., Hu, M., Chin, L., Richardson, A., Schnitt, S., Sellers, W.R. and Polyak, K. (2004) Cancer Cell, 6, 17-32.
91. Qiu, W., Hu, M., Sridhar, A., Opeskin, K., Fox, S., Shipitsin, M., Trivett, M., Thompson, E.R., Ramakrishna, M., Gorringe, K.L., Polyak, K., Haviv, I., and Campbell, I.G. (2008) Nat. Genet., 40, 650-655.
92. Desmouliere, A., Geinoz, A., Gabbiani, F. and Gabbiani, G. (1993) J. Cell Biol., 122, 103-111.
93. Serini, G., Bochaton-Piallat, M.L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L. and Gabbiani, G. (1998) J. Cell Biol., 142, 873-881.
94. Ashcroft, G.S., Yang, X., Glick, A.B., Weinstein, M., Letterio, J.L., Mizel, D.E., Anzano, M., Greenwell-Wild, T., Wahl, S.M., Deng, C. and Roberts, A.B. (1999) Nat. Cell Biol., 1, 260-266.
95. Massague, J. (2008) Cell, 134, 215-230.
96. Padua, D., Zhang, X.H., Wang, Q., Nadal, C., Gerald, W.L., Gomis, R.R. and Massague, J. (2008) Cell, 133, 66-77.
97. Ao, M., Franco, O.E., Park, D., Raman, D., Williams, K. and Hayward, S.W. (2007) Cancer Res., 67, 4244-4253.
98. Ao, M., Williams, K., Bhowmick, N.A. and Hayward, S.W. (2006) Cancer Res., 66, 8007-8016.
99. Yang, F., Strand, D.W. and Rowley, D.R. (2008) Oncogene, 27, 450-459.
100. Yang, F., Tuxhorn, J.A., Ressler, S.J., McAlhany, S.J., Dang, T.D. and Rowley, D.R. (2005) Cancer Res., 65, 8887-8895.
101. Derynck, R., Akhurst, R.J. and Balmain, A. (2001) Nat. Genet., 29, 117-19.
102. Levy, L. and Hill, C.S. (2006) Cytokine Growth Factor Rev., 17, 41-58.
103. Tang, B., Vu, M., Booker, T., Santner, S.J., Miller, F.R., Anver, M.R. and Wakefield, L.M. (2003) J. Clin. Invest., 112, 1116-1124.
104. Wakefield, L.M. and Roberts, A.B. (2002) Curr. Opin. Genet. Dev., 12, 22-29.
105. Muraoka-Cook, R.S., Shin, I., Yi, J.Y., Easterly, E., Barcellos-Hoff, M.H., Yingling, J.M., Zent, R. and Arteaga, C.L. (2006) Oncogene, 25, 3408-3423.
106. Muraoka, R.S., Dumont, N., Ritter, C.A., Dugger, T.C., Brantley, D.M., Chen, J., Easterly, E., Roebuck, L.R., Ryan, S., Gotwals, P.J., Koteliansky, V. and Arteaga, C.L. (2002) J. Clin. Invest., 109, 1551- 1559.
107. Dumont, N. and Arteaga, C.L. (2003) Cancer Cell, 3, 531-536.
108. Yingling, J.M., Blanchard, K.L. and Sawyer, J.S. (2004) Nat. Rev. Drug Discov., 3, 1011-1022.
109. Pennison, M. and Pasche, B. (2007) Curr. Opin. Oncol., 19, 579-585.
110. Arteaga, C.L. (2006) Curr. Opin. Genet. Dev., 16, 30-37.
111. Biswas, S., Criswell, T.L., Wang, S.E. and Arteaga, C.L. (2006) Clin. Cancer Res., 12, 4142-4146.
112. Coussens, L.M. and Werb, Z. (2002) Nature, 420, 860-867.
113. Raman, D., Baugher, P.J., Thu, Y.M. and Richmond, A. (2007) Cancer Lett., 256, 137-165.
114. Mueller, M.M. and Fusenig, N.E. (2004) Nat. Rev. Cancer, 4, 839- 849.
115. Basanta, D., Miodownik, M. and Baum, B. (2008) PLoS Comput. Biol., 4(3), e1000030.
116. Nowell, P.C. (1976) Science, 194, 23-28.
117. Merlo, L.M., Pepper, J.W., Reid, B.J. and Maley, C.C. (2006) Nat. Rev. Cancer, 6, 924- 935.
118. Loeb, L.A. (1991) Cancer Res., 51, 3075-3079.
119. Lengauer, C., Kinzler, K. and Vogelstein, B. (1998) Nature, 396, 643-649.
120. Tomlinson, I. and Bodmer, W. (1999) Nat. Med., 5, 11-12.
121. Loberg, R.D., Bradley, D.A., Tomlins, S.A., Chinnaiyan, A.M. and Pienta, K.J. (2007) CA. Cancer J. Clin., 57, 225-241.
122. Kraemer, K.H. (1997) Proc. Natl. Acad. Sci. USA, 94, 11-14.
123. Grossmann, J. (2002) Apoptosis, 7, 247-260.
124. Foty, R.A. and Steinberg, M.S. (2004) Int. J. Dev. Biol., 48, 397-409.
125. Bru, A., Albertos, S., Garcia-Asenjo, J.A.L. and Bru, I. (2004) Phys. Rev. Lett., 92, 238101.
126. Gatenby, R.A. and Gillies, R.J. (2008) Nat. Rev. Cancer, 8, 56-61.
127. Paget, S. (1889) Lancet, 1, 571-573.
128. Vineis, P., Matullo, G. and Manuguerra, M. (2003) J. Epidemiol. Comm. Health, 57, 89-95.
129. Anderson, A.R., Weaver, A.M., Cummings, P.T. and Quaranta, V. (2006) Cell, 127, 905-915.
130. Hanahan, D. and Weinberg, R.A. (2000) Cell, 100, 57-70.
131. Axelrod, R., Axelrod, D. and Pienta, K. (2006) Proc. Natl. Asad. Sci., 103, 13474-13479.
132. Crespi, B. and Summers, K. (2005) Trends Ecol. Evol., 20, 545-552.
133. von Neumann, J. and Morgernstern, O. (1953) Theory of games and economic behaviour. Princeton University Press, USA, Princeton, NJ.
134. Hofbauer, J. and Sigmund, K. (1998) Euolationary games and population dynamics. Cambridge University Press.
135. Basanta, D. and Deutsch, A. (2008) A game theoretical perspective on the somatic evolution of cancer. In: Selected topics in Cancer Modeling, Bellomo, N.; Chaplain, M. and de Angelis, E., Ed. Birkhauser.
136. Gatenby, R.A. and Vincent, T.L. (2003) Cancer Res., 63, 6212-6220.
137. Tomlinson, I.P.M. and Bodmer, W.F. (1997) Br. J. Cancer, 75, 157-160.
138. Basanta, D., Simon, M., Hatzikirou, H. and Deutsch, A. (2008) Cell Prolif., 41, 980-987.
139. Bach, L.A., xBentzen, A., Alsner, J. and Christiansen, F.B. (2001) Eur. J. Cancer, 37, 2116-2120.
140. Basanta, D., Hatzikirou, H. and Deutsch, A. (2008) Eur. J. Phys. B., 63, 393-397.
141. Axelrod, A. (1997) Princeton, NJ: Princeton University Press.
142. Nowak, M.A. (2006) Science, 314, 1560-1563.
143. Nowak, M. and Sigmund, K. (2005) Nature, 437, 1291-1298.
144. Barabási, A.-L. and Oltvai, Z.N. (2004) Nat. Rev. Gen., 5, 101-13.
145. Schoener, T.W. (1989) Ecology, 70(6), 1559-1589.
146. Habib, F.K., Ross, M. and Bayne, C.W. (2000) Prostate Suppl., 9, 15-20.
147. Yamada, K.M. and Cukierman, E. (2007) Cell, 130, 601- 610.
148. Kleinman, H.K. and Martin, G.R. (2005) Semin. Cancer Biol., 15, 378-386.
149. Smalley, K.S., Lioni, M. and Herlyn, M. (2006) In Vitro Cell, Dev. Biol. Anim., 42, 242-247.
150. Lang, S.H., Stark, M., Collins, A., Paul, A.B., Stower, M.J. and Maitland, N.J. (2001) Cell Growth Differ., 12, 631-640.
151. Schmeichel, K.L. and Bissell, M.J. (2003) J. Cell Sci., 116, 2377-2388.
152. Bissell, M.J. and Radisky, D. (2001) Nat. Rev. Cancer, 1, 46-54.
153. Lee, E.Y., Lee, W.H., Kaetzel, C.S., Parry, G. and Bissell, M.J. (1985) Proc. Natl. Acad. Sci. USA, 82, 1419-1423.
154. Roskelley, C.D., Desprez, P.Y. and Bissell, M.J. (1994) Proc. Natl. Acad. Sci. USA, 91, 12378-12382.
155. Barcellos-Hoff, M.H., Aggeler, J., Ram, T.G. and Bissell, M.J. (1989) Development, 105, 223-235.
156. Petersen, O.W., Ronnov-Jessen, L., Weaver, V.M. and Bissell, M.J. (1998) Adv. Cancer Res., 75, 135-161.
157. Cukierman, E., Pankov, R., Stevens, D.R. and Yamada, K.M. (2001) Science, 294, 1708-1712.
158. Weaver, V.M., Fischer, A.H., Peterson, O.W. and Bissell, M.J. (1996) Biochem. Cell Biol., 74, 833-851.
159. Weaver, V.M., Petersen, O.W., Wang, F., Larabell, C.A., Briand, P., Damsky, C. and Bissell, M.J. (1997) J. Cell Biol., 137, 231-245.
160. Gahwiler, B.H., Capogna, M., Debanne, D., McKinney, R.A. and Thompson, S.M. (1997) Trends Neurosci., 20, 471- 477.
161. Lipschutz, J.H., Foster, B.A. and Cunha, G.R. (1997) Prostate, 32, 35-42.
162. Sakai, T., Larsen, M. and Yamada, K.M. (2003) Nature, 423, 876-881.
163. Sugimura, Y., Foster, B.A., Hom, Y.K., Rubin, J.S., Finch, P.W., Aaronson, S.A., Hayashi, N., Kawamura, J. and Cunha, G.R. (1996) Int. J. Dev. Biol., 40, 941-951.
164. Tani, Y., Suttie, A., Flake, G.P., Nyska, A., and Maronpot, R.R. (2005) Vet. Pathol., 42, 306-314.
165. Bhowmick, N.A., Chytil, A., Plieth, D. Gorska, A.E., Dumont, N., Shappell, S., Washington, M.K., Neilson, E.G. and Moses, H.L. (2004) Science, 303, 848-851.
166. Dacquin, R., Starbuck, M., Schinke, T. and Karsenty, G. (2002) Dev. Dyn., 224(2), 245-251.
167. Kuhbandner, S., Brummer, S., Metzger, D., Chambon, P., Hofmann, F. and Feil, R. (2000) Genesis, 28, 15-22.
168. Miwa, T., Koyama, T. and Shirai. M. (2000) Genesis, 26, 136-138.
169. Regan, C.P., Manabe, I. and Owens, G.K. (2000) Circ. Res., 87, 363-369.
170. Zheng, B., Zhang, Z., Black, C.M., de Crombrugghe, B. and Dentonl, C.P. (2002) Am. J. Pathol., 160, 1609- 1617.
171. Iwano, M., Fischer, A., Okada, H., Plieth, D., Xue, C., Danoff, T.M. and Neilson, E.G. (2001) Mol. Ther., 3, 149-159.
172. Iwano, M., Plieth, D.T., Danoff, M. Xue, C., Okada, H. and Neilson, E.G. (2002) J. Clin. Invest., 110, 341-350.
173. Klingelhofer, J., Ambartsumian, N.S. and Lukanidin, E.M. (1997) Dev. Dyn., 210, 87-95.
174. Fukino, K., Shen, L., Matsumoto, S., Morrison, C.D., Mutter, G.L. and Eng, C. (2004) Cancer Res., 64, 7231-7236.
175. Kurose, K., Gilley, K., Matsumoto, S., Watson, P.H., Zhou, X.P. and Eng, C. (2002) Nat. Genet., 32, 355-357.
176. Paterson, R.F., Ulbright, T.M., MacLennan, G.T., Zhang, S., Pan, C.X., Sweeney, C.J., Moore, C.R., Foster, R.S., Koch, M.O., Eble, J.N. and Cheng, L. (2003) Cancer, 98, 1830-1836.
177. Hill, R., Song, Y., Cardiff, R.D. and Van Dyke, T. (2005) Cell, 123, 1001-1011.
178. Chantrain, C.F., Shimada, H., Jodele, S., Groshen, S., Ye, W., Shalinsky, D.R., Werb, Z., Coussens, L.M. and DeClerck, Y.A. (2004) Cancer Res., 64, 1675-1686.
179. Huang, S., Van Arsdall, M., Tedjarati, S., McCarty, M., Wu, W., Langley, R. and Fidler, I.J. (2002) J. Natl. Cancer Inst., 94, 1134-1142.
180. Itoh, T., Tanioka, M., Matsuda, H., Nishimoto, H., Yoshioka, T., Suzuki, R. and Uehira, M. (1999) Clin. Exp. Metastasis, 17, 177-181.
181. Placencio, V.R., Sharif-Afshar, A.R., Li, X., Huang, H., Uwamariya, C., Neilson, E.G., Shen, M.M., Matusik, R.J., Hayward, S.W. and Bhowmick, N.A. (2008) Cancer Res., 68, 4709-4718.
182. Egeblad, M., Littlepage, L.E. and Werb, Z. (2005) Cold Spring Harb. Symp. Quant. Biol., 70, 383-388.
183. Littlepage, L.E., Egeblad, M. and Werb, Z. (2005) Cancer Cell, 7, 499-500.
184. Bardeesy, N., Cheng, K.H., Berger, J.H., Chu, G.C., Pahler, J., Olson, P., Hezel, A.F., Horner, J., Lauwers, G.Y., Hanahan, D. and DePinho, R.A. (2006) Genes Dev., 20, 3130-3146.
185. Cunha, G.R., Alarid, E.T., Turner, T., Donjacour, A.A., Boutin, E.L. and Foster, B.A. (1992) J. Androl., 13, 465-475.
186. Hayward, S.W. (2002) J. Urol., 168, 1165-1172.
187. Ishii, K., Shappell, S.B., Matusik, R.J. and Hayward, S.W. (2005) Lab. Invest., 85, 1086-1103.
188. Thompson, N.L., Flanders, K.C., Smith, J.M., Ellingsworth, L.R., Roberts, A.B. and Sporn, M.B. (1989) J. Cell Biol., 108, 661-669.
189. He, Y., Franco, O.E., Jiang, M., Williams, K., Love, H.D., Coleman, I.M., Nelson, P.S. and Hayward, S.W. (2007) Cancer Res., 67, 8188-8197.
190. Anderson, A.R., Rejniak, K.A., Gerlee, P. and Quaranta, V. (2008) J. Math. Biol., 58, 579-624
191. Cappuccio, A., Elishmereni, M. and Agur, Z. (2006) Cancer Res., 66, 7293-7300.
192. Enderling, H., Chaplain, M.A., Anderson, A.R. and Vaidya, J.S. (2007) J. Theor. Biol., 246, 245- 259.
193. Clare, S.E., Nakhlis, F. and Panetta, J.C. (2000) Breast Cancer Res., 2, 430-435.
194. You, B., Tranchand, B., Girard, P., Falandry, C., Ribba, B., Chabaud, S., Souquet, P.J., Court-Fortune, I., Trillet-Lenoir, V., Fournel, C., Tod, M. and Freyer, G. (2008) Lung Cancer, 62, 261-272.
195. Araujo, R.P. and McElwain, D.L.S. (2004) Bull. Math. Biol, 66, 1039-1091.
196. Chaplain, M.A.J., Graziano, L. and Preziosi, L. (2006) Math. Med. Biol., 23, 197-229.
197. Gatenby, R.A. and Gawlinski, E.T. (1996) Cancer Res., 56, 5745-5753.
198. Sherratt, J.A. and Nowak, M.A. (1992) Proc. Biol. Sci., 248, 261-271.
199. Anderson, A.R.A., Chaplain, M.A.J., Newman, E.L., Steele, R.J.C., and Thompson, A.M. (2000) Comp. Math. Methods Med., 2, 129-154.
200. Cristini, V., Frieboes, H.B., Gatenby, R., Caserta, S., errari, M. F and Sinek, J. (2005) Clin. Cancer Res., 11, 6772-6779.
201. Anderson, A. (2007) A hybrid multiscale model of tumour invasion: evolution and the microenvironment, in Single-cellbased Models in Biology and Medicine. Anderson, A., Chaplain, M. and Rejniak, K.A., Eds. Birkhauser Verlag: Basel, pp. 3-28.
202. Quaranta, V., Rejniak, K.A., Gerlee, P. and Anderson, A.R. (2008) Semin. Cancer Biol., 18, 338-348.
203. Anderson, A.R.A. and Chaplain, M.A.J. (1998) Bull. Math. Biol., 60, 857-899.
204. Anderson, A.R.A. (2005) Math. Med. Biol., 22, 163-186.
205. Gerlee, P. and Anderson, A.R. (2008) J. Theor. Biol., 250, 705-722.
206. Rejniak, K.A. (2007) J. Theor. Biol., 247, 186-204.
207. Rejniak, K.A. (2007) Comp. Math. Methods Med., 8, 51-69.
208. Huang, P.H., Mukasa, A., Bonavia, R., Flynn, R.A., Brewer, Z.E., Cavenee, W.K., Furnari, F.B. and White, F.M. (2007) Proc. Natl. Acad. Sci. USA, 104, 12867-12872.
209. Apgar, J.F., Toettcher, J.E., Endy, D., White, F.M. and Tidor, B. (2008) PLoS Comput. Biol., 4, e30.
210. Ribba, B., Colin, T. and Schnell, S. (2006) Theor. Biol. Med. Model, 3, 7.
211. Anderson, A.R. and Quaranta, V. (2008) Nat. Rev. Cancer, 8, 227-234.