Exocytosis mechanisms underlying insulin release and glucose uptake: Conserved roles for Munc18c and syntaxin 4

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 298, Issue 3, 2010, Pages

  Jewell, Jenna L ^a   Oh, Eunjin ^a   Thurmond, Debbie C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetes; Glucose homeostasis; Glucosestimulated insulin secretion; Insulin resistance; Sec1 Munc18 proteins; Soluble N ethylmaleimide sensitive factor attachment protein receptor proteins

Indexed keywords

BINDING PROTEIN; CALCIUM BINDING PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; CELLUBREVIN; FUNGAL PROTEIN; GLUCOSE TRANSPORTER 4; INSULIN; ISOPROTEIN; MEMBRANE PROTEIN; MUNC18 PROTEIN; PROTEIN 80K H; PROTEIN CAB45B; PROTEIN DOC2 BETA; PROTEIN KINASE WNK1; PROTEIN MUNC13 1; PROTEIN SEC1; PROTEIN SNAP29; PROTEIN SYNIP; PROTEIN TOMOSYN; SNARE PROTEIN; SYNAPTOBREVIN 1; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN 1; SYNTAXIN 4; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; BINDING AFFINITY; COMPLEX FORMATION; EXOCYTOSIS; EXPERIMENTAL MODEL; GENE MUTATION; GENE OVEREXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MOBILIZATION; MOLECULAR MECHANICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REVIEW; SECRETORY GRANULE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; TRANSGENIC MOUSE; TRANSPORT VESICLE;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; EXOCYTOSIS; HUMANS; INSULIN; MUNC18 PROTEINS; QA-SNARE PROTEINS;

EID: 77749306186     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00597.2009     Document Type: Review

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