Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: A functional and gene profiling analysis

American Journal of Physiology - Endocrinology and Metabolism

Volumn 291, Issue 5, 2006, Pages

  Parton, Laura E ^a   McMillen, Patrick J ^b   Shen, Yingnian ^b   Docherty, Elizabeth ^b   Sharpe, Erin ^b   Diraison, Frédérique ^a   Briscoe, Celia P ^b   Rutter, Guy A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Glucolipotoxicity; Pancreatic islets; Sterol regulatory element binding protein 1c

Indexed keywords

CYCLIC AMP; HEPATOCYTE NUCLEAR FACTOR 3BETA; NUCLEAR FACTOR I; SECRETOGRANIN II; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SYNTAXIN; SYNTAXIN 7; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL FUNCTION; CONTROLLED STUDY; EXOCYTOSIS; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; INSULIN RELEASE; ION CURRENT; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; UNINDEXED SEQUENCE;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALCIUM; GENE EXPRESSION PROFILING; INSULIN; ISLETS OF LANGERHANS; MALE; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, ZUCKER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 33751285706     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00067.2006     Document Type: Article

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