메뉴 건너뛰기




Volumn 92, Issue 3, 2005, Pages 554-568

Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain

Author keywords

Large dense core vesicle exocytosis; Membrane fusion; Neurotransmitter release; SNARE mediated secretion; Tomosyn

Indexed keywords

DNA; ISOPROTEIN; MESSENGER RNA; PROTEIN; SNARE PROTEIN; SYNTAXIN; TOMOSYN; TOMOSYN 1; TOMOSYN 2; UNCLASSIFIED DRUG;

EID: 13244292391     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02890.x     Document Type: Article
Times cited : (41)

References (30)
  • 2
    • 0034607552 scopus 로고    scopus 로고
    • Homology-based method for identification of protein repeats using statistical significance estimates
    • Andrade M. A., Ponting C. P., Gibson T. J. and Bork P. (2000) Homology-based method for identification of protein repeats using statistical significance estimates. J. Mol. Biol. 298, 521-537.
    • (2000) J. Mol. Biol. , vol.298 , pp. 521-537
    • Andrade, M.A.1    Ponting, C.P.2    Gibson, T.J.3    Bork, P.4
  • 4
    • 0033615054 scopus 로고    scopus 로고
    • Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
    • Augustin I., Rosenmund C., Sudhof T. C. and Brose N. (1999) Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature 400, 457-461.
    • (1999) Nature , vol.400 , pp. 457-461
    • Augustin, I.1    Rosenmund, C.2    Sudhof, T.C.3    Brose, N.4
  • 6
    • 0033574464 scopus 로고    scopus 로고
    • SNARE complex formation is triggered by Ca2+ and drives membrane fusion
    • Chen Y. A., Scales S. J., Patel S. M., Doung Y. C. and Scheller R. H. (1999) SNARE complex formation is triggered by Ca2+ and drives membrane fusion. Cell 97, 165-174.
    • (1999) Cell , vol.97 , pp. 165-174
    • Chen, Y.A.1    Scales, S.J.2    Patel, S.M.3    Doung, Y.C.4    Scheller, R.H.5
  • 7
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 10
    • 17344376286 scopus 로고    scopus 로고
    • Tomosyn: A syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process
    • Fujita Y., Shirataki H., Sakisaka T. et al. (1998) Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process. Neuron 20, 905-915.
    • (1998) Neuron , vol.20 , pp. 905-915
    • Fujita, Y.1    Shirataki, H.2    Sakisaka, T.3
  • 11
    • 0042160134 scopus 로고    scopus 로고
    • SNARE regulators: Matchmakers and matchbreakers
    • Gerst J. E. (2003) SNARE regulators: matchmakers and matchbreakers. Biochim. Biophys. Acta 1641, 99-110.
    • (2003) Biochim. Biophys. Acta , vol.1641 , pp. 99-110
    • Gerst, J.E.1
  • 12
    • 0042733066 scopus 로고    scopus 로고
    • The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis
    • Hatsuzawa K., Lang T., Fasshauer D., Bruns D. and Jahn R. (2003) The R-SNARE motif of tomosyn forms SNARE core complexes with syntaxin 1 and SNAP-25 and down-regulates exocytosis. J. Biol. Chem. 278, 31 159-31 166.
    • (2003) J. Biol. Chem. , vol.278
    • Hatsuzawa, K.1    Lang, T.2    Fasshauer, D.3    Bruns, D.4    Jahn, R.5
  • 13
    • 0242653713 scopus 로고    scopus 로고
    • Impaired dendritic spine maturation in GABAA receptor alpha1 subunit knock out mice
    • Meinen K., Baker R. E., Spijker S., Rosahl T., van Pelt J. and Brussaard A. B. (2003) Impaired dendritic spine maturation in GABAA receptor alpha1 subunit knock out mice. Neuroscience 122, 699-705.
    • (2003) Neuroscience , vol.122 , pp. 699-705
    • Meinen, K.1    Baker, R.E.2    Spijker, S.3    Rosahl, T.4    Van Pelt, J.5    Brussaard, A.B.6
  • 15
    • 0035916827 scopus 로고    scopus 로고
    • A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila
    • Kraut R., Menon K. and Zinn K. (2001) A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila. Curr. Biol. 11, 417-430.
    • (2001) Curr. Biol. , vol.11 , pp. 417-430
    • Kraut, R.1    Menon, K.2    Zinn, K.3
  • 16
    • 0037187635 scopus 로고    scopus 로고
    • Prime movers of synaptic vesicle exocytosis
    • Martin T. F. (2002) Prime movers of synaptic vesicle exocytosis. Neuron 34, 9-12.
    • (2002) Neuron , vol.34 , pp. 9-12
    • Martin, T.F.1
  • 17
    • 0031696595 scopus 로고    scopus 로고
    • Tomosyn binds t-SNARE proteins via a VAMP-like coiled coil
    • Masuda E. S., Huang B. C., Fisher J. M., Luo Y. and Scheller R. H. (1998) Tomosyn binds t-SNARE proteins via a VAMP-like coiled coil. Neuron 21, 479-480.
    • (1998) Neuron , vol.21 , pp. 479-480
    • Masuda, E.S.1    Huang, B.C.2    Fisher, J.M.3    Luo, Y.4    Scheller, R.H.5
  • 18
    • 0033197735 scopus 로고    scopus 로고
    • The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion
    • McNew J. A., Weber T., Engelman D. M., Sollner T. H. and Rothman J. E. (1999) The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion. Mol. Cell 4, 415-421.
    • (1999) Mol. Cell , vol.4 , pp. 415-421
    • McNew, J.A.1    Weber, T.2    Engelman, D.M.3    Sollner, T.H.4    Rothman, J.E.5
  • 19
    • 0034704771 scopus 로고    scopus 로고
    • Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex
    • Misura K. M., Scheller R. H. and Weis W. I. (2000) Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex. Nature 404, 355-362.
    • (2000) Nature , vol.404 , pp. 355-362
    • Misura, K.M.1    Scheller, R.H.2    Weis, W.I.3
  • 20
    • 0035913332 scopus 로고    scopus 로고
    • An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
    • Richmond J. E., Weimer R. M. and Jorgensen E. M. (2001) An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412, 338-341.
    • (2001) Nature , vol.412 , pp. 338-341
    • Richmond, J.E.1    Weimer, R.M.2    Jorgensen, E.M.3
  • 21
    • 3142701373 scopus 로고    scopus 로고
    • Regulation of SNAREs by tomosyn and ROCK: Implication in extension and retraction of neurites
    • Sakisaka T., Baba T., Tanaka S., Izumi G., Yasumi M. and Takai Y. (2004) Regulation of SNAREs by tomosyn and ROCK: implication in extension and retraction of neurites. J. Cell Biol. 166, 17-25.
    • (2004) J. Cell Biol. , vol.166 , pp. 17-25
    • Sakisaka, T.1    Baba, T.2    Tanaka, S.3    Izumi, G.4    Yasumi, M.5    Takai, Y.6
  • 22
    • 3543096759 scopus 로고    scopus 로고
    • Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
    • Sutton R. B., Fasshauer D., Jahn R. and Brunger A. T. (1998) Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature 395, 347-353.
    • (1998) Nature , vol.395 , pp. 347-353
    • Sutton, R.B.1    Fasshauer, D.2    Jahn, R.3    Brunger, A.T.4
  • 23
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson J. D., Higgins D. G. and Gibson T. J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucl. Acids Res. 22, 4673-4680.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 24
    • 0037377234 scopus 로고    scopus 로고
    • Vesicle trafficking: Pleasure and pain from SM genes
    • Toonen R. F. and Verhage M. (2003) Vesicle trafficking: pleasure and pain from SM genes. Trends Cell Biol. 13, 177-186.
    • (2003) Trends Cell Biol. , vol.13 , pp. 177-186
    • Toonen, R.F.1    Verhage, M.2
  • 25
    • 0037172972 scopus 로고    scopus 로고
    • Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
    • Varoqueaux F., Sigler A., Rhee J. S., Brose N., Enk C., Reim K. and Rosenmund C. (2002) Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc. Natl Acad. Sci. USA 99, 9037-9042.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 9037-9042
    • Varoqueaux, F.1    Sigler, A.2    Rhee, J.S.3    Brose, N.4    Enk, C.5    Reim, K.6    Rosenmund, C.7
  • 26
    • 0034603030 scopus 로고    scopus 로고
    • Synaptic assembly of the brain in the absence of neurotransmitter secretion
    • Verhage M., Maia A. S., Plomp J. J. et al. (2000) Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287, 864-869.
    • (2000) Science , vol.287 , pp. 864-869
    • Verhage, M.1    Maia, A.S.2    Plomp, J.J.3
  • 28
    • 0042818205 scopus 로고    scopus 로고
    • Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation
    • Widberg C. H., Bryant N. J., Girotti M., Rea S. and James D. E. (2003) Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. J. Biol. Chem. 278, 35 093-35 101.
    • (2003) J. Biol. Chem. , vol.278
    • Widberg, C.H.1    Bryant, N.J.2    Girotti, M.3    Rea, S.4    James, D.E.5
  • 30
    • 0033525719 scopus 로고    scopus 로고
    • Three splicing variants of tomosyn and identification of their syntaxin-binding region
    • Yokoyama S., Shirataki H., Sakisaka T. and Takai Y. (1999) Three splicing variants of tomosyn and identification of their syntaxin-binding region. Biochem. Biophys. Res. Commun. 256, 218-222.
    • (1999) Biochem. Biophys. Res. Commun. , vol.256 , pp. 218-222
    • Yokoyama, S.1    Shirataki, H.2    Sakisaka, T.3    Takai, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.