Transmembrane domain length determines intracellular membrane compartment localization of syntaxins 3, 4, and 5

American Journal of Physiology - Cell Physiology

Volumn 281, Issue 1 50-1, 2001, Pages

  Watson, R T ^a   Pessin, J E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Localization; Membrane targeting; Syntaxin

Indexed keywords

GLUCOSE TRANSPORTER; INSULIN; SNARE PROTEIN; SYNTAXIN; SYNTAXIN 3; SYNTAXIN 4; SYNTAXIN 5; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL TRANSPORT; GOLGI COMPLEX; MOLECULAR INTERACTION; MOUSE; MUSCLE FIBER MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LOCALIZATION;

EID: 0034805876     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.281.1.c215     Document Type: Article

References (39)

1. Seven novel mammalian SNARE proteins localize to distinct membrane compartments
2. Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytosolic domains
3. TGN38 and its orthologues: Roles in post-TGN vesicle formation and maintenance of TGN morphology
4. The syntaxin family of vesicular transport receptors
5. A molecular description of synaptic vesicle membrane trafficking
6. A new syntaxin family member implicated in targeting of intracellular transport vesicles
7. Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking
8. Brefeldin A: The advantage of being uncompetitive
9. A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole
10. Syntaxin 5 regulates endoplasmic reticulum to Golgi transport
11. Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties
12. Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A
13. High expression of the yeast syntaxin-related Vam3 protein suppresses the protein transport defects of a pep12 null mutant
14. A targeting signal in VAMP regulating transport to synaptic vesicles
15. Retention of cytochrome b5 in the endoplasmic reticulum is transmembrane domain-dependent
16. Gene splicing by overlap extension
17. An isoform of the Golgi t-SNARE, syntaxin 5, with an endoplasmic reticulum retrieval signal
18. Synaptic vesicles and exocytosis
19. Torsin A and its torsion dystonia-associated mutant forms are luminal glycoproteins that exhibit distinct subcellular localizations
20. A C-terminally-anchored Golgi protein is inserted into the endoplasmic reticulum and then transported to the Golgi apparatus
21. The road taken: Past and future foundations of membrane traffic
22. Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes
23. Intracellular aspects of the process of protein synthesis
24. Mechanism of residence of cytochrome b(5), a tail-anchored protein, in the endoplasmic reticulum
25. Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!
26. Moving GLUT4: The biogenesis and trafficking of GLUT4 storage vesicles
27. Mechanisms of intracellular protein transport
28. Molecular dissection of the secretory pathway
29. Implications of the SNARE hypothesis for intracellular membrane topology and dynamics
30. Protein sorting by transport vesicles
31. SNAREs contribute to the specificity of membrane fusion
32. SNAP receptors implicated in vesicle targeting and fusion
33. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
34. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus
35. Yeast Golgi SNARE interactions are promiscuous
36. Functional cooperation of two independent targeting domains in syntaxin 6 is required for its efficient localization in the trans-Golgi network of 3T3L1 adipocytes
37. SNAREpins: Minimal machinery for membrane fusion
38. SNARE interactions are not selective. Implications for membrane fusion specificity
39. The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulum