Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic β cells and its physiological function in exo-endocytosis of secretory granules

Journal of Cell Science

Volumn 114, Issue 1, 2001, Pages 219-227

  Nagamatsu, Shinya ^a   Nakamichi, Yoko ^a   Watanabe, Takashi ^a   Matsushima, Satsuki ^a   Yamaguchi, Shinya ^a   Ni, Jian ^b   Itagaki, Eiji ^a   Ishida, Hitoshi ^a  

^a KYORIN UNIVERSITY   (Japan)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Cellubrevin; Endobrevin; Endosome; Exocytosis; GABA; GFP; Insulin; SNARE

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIGEN; CELL PROTEIN; CELLUBREVIN; ENDOBREVIN; FLUORESCENT DYE; GLUCOSE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INSULIN; SYNTAXIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ARTICLE; CELL STRAIN; CELL VACUOLE; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; EXOCYTOSIS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULINOMA; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RAT; RECYCLING; SECRETORY GRANULE;

ANIMALS; ENDOCYTOSIS; ENDOSOMES; EXOCYTOSIS; FLUORESCENT DYES; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; HUMANS; INSULIN; ISLETS OF LANGERHANS; MEMBRANE PROTEINS; PEPTIDES; PYRIDINIUM COMPOUNDS; QA-SNARE PROTEINS; QUATERNARY AMMONIUM COMPOUNDS; R-SNARE PROTEINS; RATS; RECEPTORS, TRANSFERRIN; RECOMBINANT FUSION PROTEINS; SECRETORY VESICLES; SYNTAXIN 1; VESICLE-ASSOCIATED MEMBRANE PROTEIN 3; XANTHENES;

ANIMALIA;

EID: 0035151221     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Boyd, R. S., Duggan, M. J., Shone, C. C. and Foster, K. A. (1995). The effect of botulinum neurotoxins on the release of insulin from the insulinoma cell lines HIT-15 and RINm5F. J. Biol. Chem. 270, 18216-18218.
2. Bucci, C., Parton, R. G., Mather, I. H., Stunnenberg, H., Simons, K., Hoflack, B. and Zerial, M. (1992). The small GTPase Rab5a functions as a regulatory factor in the early endocytotic pathway. Cell 70, 715-728.
3. Chavrier, P., Parton, R. G., Hauri, H. P., Simons. K. and Zerial, M. (1990). Localizations of the low molecular weight GTP binding proteins to exocytotic and endocytotic compartments. Cell 62, 317-329.
4. Chilcote, T. J., Galli, T., Mundigl, O., Edelmann, L., McPherson, P. S., takei, K. and De Camilli, P. (1995). Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells. J. Cell Biol. 129, 219-231.
5. Chomczynski, P. and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
6. Tagaya, M., Toyonaga, S., Takahashi, M., Yamamoto, A., Fujiwara, T., Akagawa, K., Moriyama, Y. and Mizushima, S. (1995). Syntaxin 1(HPC-1) is associated with chromaffin granules. J. Biol. Chem. 270, 15930-15933.
7. Takei, K., Mundigl, O., Daniell, L. and De Camilli, P. (1996). The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin. J. Cell Biol. 133, 1237-1250.
8. Trimble, W. S., Gray, T. S., Elferink, L. A., Wilson, M. C. and Scheller, R. H. (1990). Distinct pattern of expression of two VAMP genes within the rat brain. J. Neurosci. 10, 1380-1387.
9. Volchuk, A., Sargeant, R., Sumitani, S., Liu, Z., He, L. and Klip, A. (1995). Cellubrevin is a resident protein of insulin-sensitive GLUT4 glucose transporter vesicles in 3T3-L1 adipocytes. J. Biol. Chem. 270, 8233-8240.
10. Wheeler, M. B., Sheu, L., Ghai, M., Bouquillon, A., Grondin, G., Weller, U., Beaudoin, A. R., Bennett, M. K., Trimble, W. S. and Gaisano, H. Y. (1996). Characterization of SNARE protein expression in β cell lines and pancreatic islet. Endocrinology 137, 1340-1348.
11. 2+ and G-proteins. Diabetes Reviews 4, 276-297.
12. Wong, S. H., Zhang, T., Xu, Y., Subramaniam, V. N., Griffiths, G. and Hong, W. (1998). Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome. Mol. Biol. Cell 9, 1549-1563.