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Volumn 56, Issue 1, 2010, Pages 86-93

Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences

Author keywords

5 aza 2' deoxycytidine; Decitabine; DNA methylation; Epigenetics; Histone modification

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CIRCADIAN RHYTHM SIGNALING PROTEIN; CLU PROTEIN, MOUSE; CLUSTERIN; DIPEPTIDASE; DNA METHYLTRANSFERASE; DRUG DERIVATIVE; ENZYME INHIBITOR; HOMEODOMAIN PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PER1 PROTEIN, MOUSE; SALL3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

EID: 77649299465     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.20247     Document Type: Article
Times cited : (10)

References (51)
  • 2
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 3
    • 0038528151 scopus 로고    scopus 로고
    • Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML)
    • Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U. Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML). Leukemia 2003; 17: 910-918.
    • (2003) Leukemia , vol.17 , pp. 910-918
    • Tessema, M.1    Langer, F.2    Dingemann, J.3    Ganser, A.4    Kreipe, H.5    Lehmann, U.6
  • 4
    • 0020032366 scopus 로고
    • Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
    • Creusot F, Acs G, Christman JK. Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine. J Biol Chem 1982; 257: 2041-2048.
    • (1982) J Biol Chem , vol.257 , pp. 2041-2048
    • Creusot, F.1    Acs, G.2    Christman, J.K.3
  • 6
    • 0041939756 scopus 로고    scopus 로고
    • Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
    • Villar-Garea A, Fraga MF, Espada J, Esteller M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res 2003; 63: 4984-4989.
    • (2003) Cancer Res , vol.63 , pp. 4984-4989
    • Villar-Garea, A.1    Fraga, M.F.2    Espada, J.3    Esteller, M.4
  • 7
    • 55949095127 scopus 로고    scopus 로고
    • Chromatin, cancer and drug therapies
    • Cortez CC, Jones PA. Chromatin, cancer and drug therapies. Mutat Res 2008; 647: 44-51.
    • (2008) Mutat Res , vol.647 , pp. 44-51
    • Cortez, C.C.1    Jones, P.A.2
  • 8
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment
    • Daskalakis M, Nguyen TT, Nguyen C, Guldberg P, Kohler G, Wijermans P, Jones PA, Lubbert M. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood 2002; 100: 2957-2964.
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Kohler, G.5    Wijermans, P.6    Jones, P.A.7    Lubbert, M.8
  • 11
    • 52049102456 scopus 로고    scopus 로고
    • Evolution of decitabine development: Accomplishments, ongoing investigations, and future strategies
    • Jabbour E, Issa JP, Garcia-Manero G, Kantarjian H. Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. Cancer 2008; 112: 2341-2351.
    • (2008) Cancer , vol.112 , pp. 2341-2351
    • Jabbour, E.1    Issa, J.P.2    Garcia-Manero, G.3    Kantarjian, H.4
  • 14
    • 1542563409 scopus 로고    scopus 로고
    • Initial sequencing and comparative analysis of the mouse genome
    • Waterston RH, Lindblad-Toh K, Birney E, et al. Initial sequencing and comparative analysis of the mouse genome. Nature 2002; 420: 520-562.
    • (2002) Nature , vol.420 , pp. 520-562
    • Waterston, R.H.1    Lindblad-Toh, K.2    Birney, E.3
  • 15
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32: e38.
    • (2004) Nucleic Acids Res , vol.e38 , pp. 32
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6
  • 16
    • 24044479394 scopus 로고    scopus 로고
    • Estimating the total mouse DNA methylation according to the B1 repetitive elements
    • Jeong KS, Lee S. Estimating the total mouse DNA methylation according to the B1 repetitive elements. Biochem Biophys Res Commun 2005; 335: 1211-1216.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1211-1216
    • Jeong, K.S.1    Lee, S.2
  • 18
    • 34250188803 scopus 로고    scopus 로고
    • Genomic patterns of DNA methylation: Targets and function of an epigenetic mark
    • Weber M, Schubeler D. Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol 2007; 19: 273-280.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 273-280
    • Weber, M.1    Schubeler, D.2
  • 20
    • 2342437315 scopus 로고    scopus 로고
    • Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells
    • Hattori N, Nishino K, Ko YG, Hattori N, Ohgane J, Tanaka S, Shiota K. Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem 2004; 279: 17063-17069.
    • (2004) J Biol Chem , vol.279 , pp. 17063-17069
    • Hattori, N.1    Nishino, K.2    Ko, Y.G.3    Hattori, N.4    Ohgane, J.5    Tanaka, S.6    Shiota, K.7
  • 23
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen T, Ueda Y, Dodge JE, Wang Z, Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 2003; 23: 5594-5605.
    • (2003) Mol Cell Biol , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 25
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M, Jenuwein T. The many faces of histone lysine methylation. Curr Opin Cell Biol 2002; 14: 286-298.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 26
    • 0037648396 scopus 로고    scopus 로고
    • Maintenance of chromatin states: An open-andshut case
    • Vermaak D, Ahmad K, Henikoff S. Maintenance of chromatin states: an open-andshut case. Curr Opin Cell Biol 2003; 15: 266-274.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 266-274
    • Vermaak, D.1    Ahmad, K.2    Henikoff, S.3
  • 28
    • 70349332644 scopus 로고    scopus 로고
    • Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development
    • Ikegami K, Ohgane J, Tanaka S, Yagi S, Shiota K. Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development. Int J Dev Biol 2009; 53: 203-214.
    • (2009) Int J Dev Biol , vol.53 , pp. 203-214
    • Ikegami, K.1    Ohgane, J.2    Tanaka, S.3    Yagi, S.4    Shiota, K.5
  • 29
    • 0024435296 scopus 로고
    • The organization of the mouse satellite DNA at centromeres
    • Joseph A, Mitchell AR, Miller OJ. The organization of the mouse satellite DNA at centromeres. Exp Cell Res 1989; 183: 494-500.
    • (1989) Exp Cell Res , vol.183 , pp. 494-500
    • Joseph, A.1    Mitchell, A.R.2    Miller, O.J.3
  • 30
    • 0026551176 scopus 로고
    • Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system
    • Davidson S, Crowther P, Radley J, Woodcock D. Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system. Eur J Cancer 1992; 28: 362-368.
    • (1992) Eur J Cancer , vol.28 , pp. 362-368
    • Davidson, S.1    Crowther, P.2    Radley, J.3    Woodcock, D.4
  • 31
    • 0027978363 scopus 로고
    • Regulators for the rat clusterin gene: DNA methylation and cis-acting regulatory elements
    • Rosemblit N, Chen CL. Regulators for the rat clusterin gene: DNA methylation and cis-acting regulatory elements. J Mol Endocrinol 1994; 13: 69-76.
    • (1994) J Mol Endocrinol , vol.13 , pp. 69-76
    • Rosemblit, N.1    Chen, C.L.2
  • 32
    • 2442450761 scopus 로고    scopus 로고
    • Dipeptidase 1: A candidate tumor-specific molecular marker in colorectal carcinoma
    • McIver CM, Lloyd JM, Hewett PJ, Hardingham JE. Dipeptidase 1: a candidate tumor-specific molecular marker in colorectal carcinoma. Cancer Lett 2004; 209: 67-74.
    • (2004) Cancer Lett , vol.209 , pp. 67-74
    • McIver, C.M.1    Lloyd, J.M.2    Hewett, P.J.3    Hardingham, J.E.4
  • 33
    • 0027400888 scopus 로고
    • Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
    • Stoger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H Barlow DP. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993; 73: 61-71.
    • (1993) Cell , vol.73 , pp. 61-71
    • Stoger, R.1    Kubicka, P.2    Liu, C.G.3    Kafri, T.4    Razin, A.5    Cedar, H.6    Barlow, D.P.7
  • 34
    • 0037041422 scopus 로고    scopus 로고
    • Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
    • Jackson JP, Lindroth AM, Cao X, Jacobsen SE. Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 2002; 416: 556-560.
    • (2002) Nature , vol.416 , pp. 556-560
    • Jackson, J.P.1    Lindroth, A.M.2    Cao, X.3    Jacobsen, S.E.4
  • 37
    • 33846038833 scopus 로고    scopus 로고
    • 5-Aza-2'-deoxycytidine- mediated reductions in G9A histone methyltransferase and histone H3 K9 dimethylation levels are linked to tumor suppressor gene reactivation
    • Wozniak RJ, Klimecki WT, Lau SS, Feinstein Y, Futscher BW. 5-Aza-2'-deoxycytidine- mediated reductions in G9A histone methyltransferase and histone H3 K9 dimethylation levels are linked to tumor suppressor gene reactivation. Oncogene 2007; 26: 77-90.
    • (2007) Oncogene , vol.26 , pp. 77-90
    • Wozniak, R.J.1    Klimecki, W.T.2    Lau, S.S.3    Feinstein, Y.4    Futscher, B.W.5
  • 38
    • 0037112369 scopus 로고    scopus 로고
    • Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine
    • Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, Jones PA. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Res 2002; 62: 6456-6461.
    • (2002) Cancer Res , vol.62 , pp. 6456-6461
    • Nguyen, C.T.1    Weisenberger, D.J.2    Velicescu, M.3    Gonzales, F.A.4    Lin, J.C.5    Liang, G.6    Jones, P.A.7
  • 39
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • Fahrner JA, Eguchi S, Herman JG, Baylin SB. Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res 2002; 62: 7213-7218.
    • (2002) Cancer Res , vol.62 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 40
    • 0038412822 scopus 로고    scopus 로고
    • The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
    • Fuks F, Hurd PJ, Deplus R, Kouzarides T. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 2003; 31: 2305-2312.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2305-2312
    • Fuks, F.1    Hurd, P.J.2    Deplus, R.3    Kouzarides, T.4
  • 41
    • 33745811234 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
    • Li H, Rauch T, Chen ZX, Szabo PE, Riggs AD, Pfeifer GP. The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J Biol Chem 2006; 281: 19489-19500.
    • (2006) J Biol Chem , vol.281 , pp. 19489-19500
    • Li, H.1    Rauch, T.2    Chen, Z.X.3    Szabo, P.E.4    Riggs, A.D.5    Pfeifer, G.P.6
  • 43
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998; 393: 386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 47
    • 33645751058 scopus 로고    scopus 로고
    • Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
    • McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T, Baylin SB. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res 2006; 66: 3541-3549.
    • (2006) Cancer Res , vol.66 , pp. 3541-3549
    • McGarvey, K.M.1    Fahrner, J.A.2    Greene, E.3    Martens, J.4    Jenuwein, T.5    Baylin, S.B.6
  • 49
    • 33846905189 scopus 로고    scopus 로고
    • Distinctive signatures of histone methylation in transcribed coding and noncoding human β-globin sequences
    • Kim A, Kiefer C, Dean A. Distinctive signatures of histone methylation in transcribed coding and noncoding human β-globin sequences. Mol Cell Biol 2007; 27: 1271-1279.
    • (2007) Mol Cell Biol , vol.27 , pp. 1271-1279
    • Kim, A.1    Kiefer, C.2    Dean, A.3
  • 50
    • 23044431656 scopus 로고    scopus 로고
    • Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
    • Vakoc C, Mandat S, Olenchock B, Blobel GA. Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin. Mol Cell 2005; 19: 381-391.
    • (2005) Mol Cell , vol.19 , pp. 381-391
    • Vakoc, C.1    Mandat, S.2    Olenchock, B.3    Blobel, G.A.4
  • 51
    • 0028151343 scopus 로고
    • Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
    • Juttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 1994; 91: 11797-11801.
    • (1994) Proc Natl Acad Sci Usa , vol.91 , pp. 11797-11801
    • Juttermann, R.1    Li, E.2    Jaenisch, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.