-
1
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998; 95: 6870-6875.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
Markowitz, S.7
Willson, J.K.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
2
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
Baylin, S.B.4
Herman, J.G.5
-
3
-
-
0038528151
-
Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML)
-
Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U. Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML). Leukemia 2003; 17: 910-918.
-
(2003)
Leukemia
, vol.17
, pp. 910-918
-
-
Tessema, M.1
Langer, F.2
Dingemann, J.3
Ganser, A.4
Kreipe, H.5
Lehmann, U.6
-
4
-
-
0020032366
-
Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine
-
Creusot F, Acs G, Christman JK. Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine. J Biol Chem 1982; 257: 2041-2048.
-
(1982)
J Biol Chem
, vol.257
, pp. 2041-2048
-
-
Creusot, F.1
Acs, G.2
Christman, J.K.3
-
5
-
-
1642499364
-
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells
-
Cheng JC, Weisenberger DJ, Gonzales FA, Liang G, Xu GL, Hu YG, Marquez VE, Jones PA. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol 2004; 24: 1270-1278.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1270-1278
-
-
Cheng, J.C.1
Weisenberger, D.J.2
Gonzales, F.A.3
Liang, G.4
Xu, G.L.5
Hu, Y.G.6
Marquez, V.E.7
Jones, P.A.8
-
6
-
-
0041939756
-
Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells
-
Villar-Garea A, Fraga MF, Espada J, Esteller M. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res 2003; 63: 4984-4989.
-
(2003)
Cancer Res
, vol.63
, pp. 4984-4989
-
-
Villar-Garea, A.1
Fraga, M.F.2
Espada, J.3
Esteller, M.4
-
7
-
-
55949095127
-
Chromatin, cancer and drug therapies
-
Cortez CC, Jones PA. Chromatin, cancer and drug therapies. Mutat Res 2008; 647: 44-51.
-
(2008)
Mutat Res
, vol.647
, pp. 44-51
-
-
Cortez, C.C.1
Jones, P.A.2
-
8
-
-
0037108309
-
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment
-
Daskalakis M, Nguyen TT, Nguyen C, Guldberg P, Kohler G, Wijermans P, Jones PA, Lubbert M. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood 2002; 100: 2957-2964.
-
(2002)
Blood
, vol.100
, pp. 2957-2964
-
-
Daskalakis, M.1
Nguyen, T.T.2
Nguyen, C.3
Guldberg, P.4
Kohler, G.5
Wijermans, P.6
Jones, P.A.7
Lubbert, M.8
-
9
-
-
0035935980
-
Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells
-
Zhu WG, Dai Z, Ding H, Srinivasan K, Hall J, Duan W, Villalona-Calero MA, Plass C, Otterson GA. Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells. Oncogene 2001; 20: 7787-7796.
-
(2001)
Oncogene
, vol.20
, pp. 7787-7796
-
-
Zhu, W.G.1
Dai, Z.2
Ding, H.3
Srinivasan, K.4
Hall, J.5
Duan, W.6
Villalona-Calero, M.A.7
Plass, C.8
Otterson, G.A.9
-
10
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa JP, Garcia-Manero G, Giles FJ, Mannari R, Thomas D, Faderl S, Bayar E, Lyons J, Rosenfeld CS, Cortes J, Kantarjian HM. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004; 103: 1635-1640.
-
(2004)
Blood
, vol.103
, pp. 1635-1640
-
-
Issa, J.P.1
Garcia-Manero, G.2
Giles, F.J.3
Mannari, R.4
Thomas, D.5
Faderl, S.6
Bayar, E.7
Lyons, J.8
Rosenfeld, C.S.9
Cortes, J.10
Kantarjian, H.M.11
-
11
-
-
52049102456
-
Evolution of decitabine development: Accomplishments, ongoing investigations, and future strategies
-
Jabbour E, Issa JP, Garcia-Manero G, Kantarjian H. Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. Cancer 2008; 112: 2341-2351.
-
(2008)
Cancer
, vol.112
, pp. 2341-2351
-
-
Jabbour, E.1
Issa, J.P.2
Garcia-Manero, G.3
Kantarjian, H.4
-
12
-
-
0344211845
-
Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias
-
de Lima M, Ravandi F, Shahjahan M, Andersson B, Couriel D, Donato M, Khouri I, Gajewski J, van Besien K, Champlin R, Giralt S, Kantarjian H. Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. Cancer 2003; 97: 1242-1247.
-
(2003)
Cancer
, vol.97
, pp. 1242-1247
-
-
de Lima, M.1
Ravandi, F.2
Shahjahan, M.3
Andersson, B.4
Couriel, D.5
Donato, M.6
Khouri, I.7
Gajewski, J.8
van Besien, K.9
Champlin, R.10
Giralt, S.11
Kantarjian, H.12
-
14
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston RH, Lindblad-Toh K, Birney E, et al. Initial sequencing and comparative analysis of the mouse genome. Nature 2002; 420: 520-562.
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
Lindblad-Toh, K.2
Birney, E.3
-
15
-
-
2342557977
-
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
-
Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32: e38.
-
(2004)
Nucleic Acids Res
, vol.e38
, pp. 32
-
-
Yang, A.S.1
Estecio, M.R.2
Doshi, K.3
Kondo, Y.4
Tajara, E.H.5
Issa, J.P.6
-
16
-
-
24044479394
-
Estimating the total mouse DNA methylation according to the B1 repetitive elements
-
Jeong KS, Lee S. Estimating the total mouse DNA methylation according to the B1 repetitive elements. Biochem Biophys Res Commun 2005; 335: 1211-1216.
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 1211-1216
-
-
Jeong, K.S.1
Lee, S.2
-
17
-
-
0030867514
-
DNA demethylation and pericentromeric rearrangements of chromosome 1
-
Ji W, Hernandez R, Zhang XY, Qu GZ, Frady A, Varela M, Ehrlich M. DNA demethylation and pericentromeric rearrangements of chromosome 1. Mutat Res 1997; 379: 33-41.
-
(1997)
Mutat Res
, vol.379
, pp. 33-41
-
-
Ji, W.1
Hernandez, R.2
Zhang, X.Y.3
Qu, G.Z.4
Frady, A.5
Varela, M.6
Ehrlich, M.7
-
18
-
-
34250188803
-
Genomic patterns of DNA methylation: Targets and function of an epigenetic mark
-
Weber M, Schubeler D. Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol 2007; 19: 273-280.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 273-280
-
-
Weber, M.1
Schubeler, D.2
-
19
-
-
0036734599
-
Epigenetic marks by DNA methylation specific to stem, germ and somatic cells in mice
-
Shiota K, Kogo Y, Ohgane J, Imamura T, Urano A, Nishino K, Tanaka S, Hattori N. Epigenetic marks by DNA methylation specific to stem, germ and somatic cells in mice. Genes Cells 2002; 7: 961-969.
-
(2002)
Genes Cells
, vol.7
, pp. 961-969
-
-
Shiota, K.1
Kogo, Y.2
Ohgane, J.3
Imamura, T.4
Urano, A.5
Nishino, K.6
Tanaka, S.7
Hattori, N.8
-
20
-
-
2342437315
-
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells
-
Hattori N, Nishino K, Ko YG, Hattori N, Ohgane J, Tanaka S, Shiota K. Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem 2004; 279: 17063-17069.
-
(2004)
J Biol Chem
, vol.279
, pp. 17063-17069
-
-
Hattori, N.1
Nishino, K.2
Ko, Y.G.3
Hattori, N.4
Ohgane, J.5
Tanaka, S.6
Shiota, K.7
-
21
-
-
12144288917
-
The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice
-
Ohgane J, Wakayama T, Senda S, Yamazaki Y, Inoue K, Ogura A, Marh J, Tanaka S, Yanagimachi R, Shiota K. The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice. Genes Cells 2004; 9: 253-260.
-
(2004)
Genes Cells
, vol.9
, pp. 253-260
-
-
Ohgane, J.1
Wakayama, T.2
Senda, S.3
Yamazaki, Y.4
Inoue, K.5
Ogura, A.6
Marh, J.7
Tanaka, S.8
Yanagimachi, R.9
Shiota, K.10
-
22
-
-
0036135014
-
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
-
Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, Laird PW, Jones PA. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol 2002; 22: 480-491.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 480-491
-
-
Liang, G.1
Chan, M.F.2
Tomigahara, Y.3
Tsai, Y.C.4
Gonzales, F.A.5
Li, E.6
Laird, P.W.7
Jones, P.A.8
-
23
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen T, Ueda Y, Dodge JE, Wang Z, Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 2003; 23: 5594-5605.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
24
-
-
4644221440
-
Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells
-
Hattori N, Abe T, Hattori N, Suzuki M, Matsuyama T, Yoshida S, Li E, Shiota K. Preference of DNA methyltransferases for CpG islands in mouse embryonic stem cells. Genome Res 2004; 14: 1733-1740.
-
(2004)
Genome Res
, vol.14
, pp. 1733-1740
-
-
Hattori, N.1
Abe, T.2
Hattori, N.3
Suzuki, M.4
Matsuyama, T.5
Yoshida, S.6
Li, E.7
Shiota, K.8
-
25
-
-
0036591878
-
The many faces of histone lysine methylation
-
Lachner M, Jenuwein T. The many faces of histone lysine methylation. Curr Opin Cell Biol 2002; 14: 286-298.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 286-298
-
-
Lachner, M.1
Jenuwein, T.2
-
26
-
-
0037648396
-
Maintenance of chromatin states: An open-andshut case
-
Vermaak D, Ahmad K, Henikoff S. Maintenance of chromatin states: an open-andshut case. Curr Opin Cell Biol 2003; 15: 266-274.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 266-274
-
-
Vermaak, D.1
Ahmad, K.2
Henikoff, S.3
-
27
-
-
33845781998
-
Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells
-
Ikegami K, Iwatani M, Suzuki M, Tachibana M, Shinkai Y, Tanaka S, Greally JM, Yagi S, Hattori N, Shiota K. Genome-wide and locus-specific DNA hypomethylation in G9a deficient mouse embryonic stem cells. Genes Cells 2007; 1: 1-11.
-
(2007)
Genes Cells
, vol.1
, pp. 1-11
-
-
Ikegami, K.1
Iwatani, M.2
Suzuki, M.3
Tachibana, M.4
Shinkai, Y.5
Tanaka, S.6
Greally, J.M.7
Yagi, S.8
Hattori, N.9
Shiota, K.10
-
28
-
-
70349332644
-
Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development
-
Ikegami K, Ohgane J, Tanaka S, Yagi S, Shiota K. Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development. Int J Dev Biol 2009; 53: 203-214.
-
(2009)
Int J Dev Biol
, vol.53
, pp. 203-214
-
-
Ikegami, K.1
Ohgane, J.2
Tanaka, S.3
Yagi, S.4
Shiota, K.5
-
29
-
-
0024435296
-
The organization of the mouse satellite DNA at centromeres
-
Joseph A, Mitchell AR, Miller OJ. The organization of the mouse satellite DNA at centromeres. Exp Cell Res 1989; 183: 494-500.
-
(1989)
Exp Cell Res
, vol.183
, pp. 494-500
-
-
Joseph, A.1
Mitchell, A.R.2
Miller, O.J.3
-
30
-
-
0026551176
-
Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system
-
Davidson S, Crowther P, Radley J, Woodcock D. Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system. Eur J Cancer 1992; 28: 362-368.
-
(1992)
Eur J Cancer
, vol.28
, pp. 362-368
-
-
Davidson, S.1
Crowther, P.2
Radley, J.3
Woodcock, D.4
-
31
-
-
0027978363
-
Regulators for the rat clusterin gene: DNA methylation and cis-acting regulatory elements
-
Rosemblit N, Chen CL. Regulators for the rat clusterin gene: DNA methylation and cis-acting regulatory elements. J Mol Endocrinol 1994; 13: 69-76.
-
(1994)
J Mol Endocrinol
, vol.13
, pp. 69-76
-
-
Rosemblit, N.1
Chen, C.L.2
-
32
-
-
2442450761
-
Dipeptidase 1: A candidate tumor-specific molecular marker in colorectal carcinoma
-
McIver CM, Lloyd JM, Hewett PJ, Hardingham JE. Dipeptidase 1: a candidate tumor-specific molecular marker in colorectal carcinoma. Cancer Lett 2004; 209: 67-74.
-
(2004)
Cancer Lett
, vol.209
, pp. 67-74
-
-
McIver, C.M.1
Lloyd, J.M.2
Hewett, P.J.3
Hardingham, J.E.4
-
33
-
-
0027400888
-
Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal
-
Stoger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H Barlow DP. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993; 73: 61-71.
-
(1993)
Cell
, vol.73
, pp. 61-71
-
-
Stoger, R.1
Kubicka, P.2
Liu, C.G.3
Kafri, T.4
Razin, A.5
Cedar, H.6
Barlow, D.P.7
-
34
-
-
0037041422
-
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
-
Jackson JP, Lindroth AM, Cao X, Jacobsen SE. Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 2002; 416: 556-560.
-
(2002)
Nature
, vol.416
, pp. 556-560
-
-
Jackson, J.P.1
Lindroth, A.M.2
Cao, X.3
Jacobsen, S.E.4
-
35
-
-
0037693853
-
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa
-
Tamaru H, Zhang X, McMillen D, Singh PB, Nakayama J, Grewal SI, Allis CD, Cheng X, Selker EU. Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa. Nat Genet 2003; 34: 75-79.
-
(2003)
Nat Genet
, vol.34
, pp. 75-79
-
-
Tamaru, H.1
Zhang, X.2
McMillen, D.3
Singh, P.B.4
Nakayama, J.5
Grewal, S.I.6
Allis, C.D.7
Cheng, X.8
Selker, E.U.9
-
36
-
-
0032480226
-
DNA hypomethylation leads to elevated mutation rates
-
Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature 1998; 395: 89-93.
-
(1998)
Nature
, vol.395
, pp. 89-93
-
-
Chen, R.Z.1
Pettersson, U.2
Beard, C.3
Jackson-Grusby, L.4
Jaenisch, R.5
-
37
-
-
33846038833
-
5-Aza-2'-deoxycytidine- mediated reductions in G9A histone methyltransferase and histone H3 K9 dimethylation levels are linked to tumor suppressor gene reactivation
-
Wozniak RJ, Klimecki WT, Lau SS, Feinstein Y, Futscher BW. 5-Aza-2'-deoxycytidine- mediated reductions in G9A histone methyltransferase and histone H3 K9 dimethylation levels are linked to tumor suppressor gene reactivation. Oncogene 2007; 26: 77-90.
-
(2007)
Oncogene
, vol.26
, pp. 77-90
-
-
Wozniak, R.J.1
Klimecki, W.T.2
Lau, S.S.3
Feinstein, Y.4
Futscher, B.W.5
-
38
-
-
0037112369
-
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine
-
Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, Jones PA. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Res 2002; 62: 6456-6461.
-
(2002)
Cancer Res
, vol.62
, pp. 6456-6461
-
-
Nguyen, C.T.1
Weisenberger, D.J.2
Velicescu, M.3
Gonzales, F.A.4
Lin, J.C.5
Liang, G.6
Jones, P.A.7
-
39
-
-
0037115392
-
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
-
Fahrner JA, Eguchi S, Herman JG, Baylin SB. Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res 2002; 62: 7213-7218.
-
(2002)
Cancer Res
, vol.62
, pp. 7213-7218
-
-
Fahrner, J.A.1
Eguchi, S.2
Herman, J.G.3
Baylin, S.B.4
-
40
-
-
0038412822
-
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
-
Fuks F, Hurd PJ, Deplus R, Kouzarides T. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 2003; 31: 2305-2312.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
41
-
-
33745811234
-
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
-
Li H, Rauch T, Chen ZX, Szabo PE, Riggs AD, Pfeifer GP. The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J Biol Chem 2006; 281: 19489-19500.
-
(2006)
J Biol Chem
, vol.281
, pp. 19489-19500
-
-
Li, H.1
Rauch, T.2
Chen, Z.X.3
Szabo, P.E.4
Riggs, A.D.5
Pfeifer, G.P.6
-
42
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, Strouboulis J, Wolffe AP. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 1998; 19: 187-191.
-
(1998)
Nat Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
43
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 1998; 393: 386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
44
-
-
0034720284
-
CpG methylation is maintained in human cancer cells lacking DNMT1
-
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG., Kinzler KW, Vogelstein B, Baylin SB, Schuebel KE. CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 2000; 404: 1003-1007.
-
(2000)
Nature
, vol.404
, pp. 1003-1007
-
-
Rhee, I.1
Jair, K.W.2
Yen, R.W.3
Lengauer, C.4
Herman, J.G.5
Kinzler, K.W.6
Vogelstein, B.7
Baylin, S.B.8
Schuebel, K.E.9
-
45
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002; 416: 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
46
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
Santos-Rosa H, Schneider R, Bannister AJ, Sherriff J, Bernstein BE, Emre NC, Schreiber SL, Mellor J, Kouzarides T. Active genes are tri-methylated at K4 of histone H3. Nature 2002; 419: 407-411.
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
Schneider, R.2
Bannister, A.J.3
Sherriff, J.4
Bernstein, B.E.5
Emre, N.C.6
Schreiber, S.L.7
Mellor, J.8
Kouzarides, T.9
-
47
-
-
33645751058
-
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
-
McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T, Baylin SB. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res 2006; 66: 3541-3549.
-
(2006)
Cancer Res
, vol.66
, pp. 3541-3549
-
-
McGarvey, K.M.1
Fahrner, J.A.2
Greene, E.3
Martens, J.4
Jenuwein, T.5
Baylin, S.B.6
-
48
-
-
33744783407
-
Histone modification patterns associated with the human X chromosome
-
Brinkman AB, Roelofsen T, Pennings S, Martens J, Jenuwein T, Stunnenberg HG. Histone modification patterns associated with the human X chromosome. EMBO Rep 2006; 7: 628-634.
-
(2006)
Embo Rep
, vol.7
, pp. 628-634
-
-
Brinkman, A.B.1
Roelofsen, T.2
Pennings, S.3
Martens, J.4
Jenuwein, T.5
Stunnenberg, H.G.6
-
49
-
-
33846905189
-
Distinctive signatures of histone methylation in transcribed coding and noncoding human β-globin sequences
-
Kim A, Kiefer C, Dean A. Distinctive signatures of histone methylation in transcribed coding and noncoding human β-globin sequences. Mol Cell Biol 2007; 27: 1271-1279.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1271-1279
-
-
Kim, A.1
Kiefer, C.2
Dean, A.3
-
50
-
-
23044431656
-
Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
-
Vakoc C, Mandat S, Olenchock B, Blobel GA. Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin. Mol Cell 2005; 19: 381-391.
-
(2005)
Mol Cell
, vol.19
, pp. 381-391
-
-
Vakoc, C.1
Mandat, S.2
Olenchock, B.3
Blobel, G.A.4
-
51
-
-
0028151343
-
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 1994; 91: 11797-11801.
-
(1994)
Proc Natl Acad Sci Usa
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
|