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Volumn 15, Issue 3, 2003, Pages 266-274

Maintenance of chromatin states: An open-and-shut case

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DOUBLE STRANDED RNA; HISTONE; NUCLEASE; PROTEIN SUBUNIT; REPETITIVE DNA; RNA; RNA POLYMERASE II;

EID: 0037648396     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(03)00043-7     Document Type: Review
Times cited : (116)

References (76)
  • 1
    • 0000540894 scopus 로고
    • Heterochromatin, chromocentren, chromomeren
    • [English translation: Heterochromatin, chromocentres, chromomeres.]
    • Heitz E. Heterochromatin, chromocentren, chromomeren. Ber. Deutsch. Bot. Ges. 47:1929;274-284. [English translation: Heterochromatin, chromocentres, chromomeres.].
    • (1929) Ber. Deutsch. Bot. Ges. , vol.47 , pp. 274-284
    • Heitz, E.1
  • 2
    • 0017142124 scopus 로고
    • Chromosomal subunits in active genes have an altered conformation
    • Weintraub H., Groudine M. Chromosomal subunits in active genes have an altered conformation. Science. 193:1976;848-856.
    • (1976) Science , vol.193 , pp. 848-856
    • Weintraub, H.1    Groudine, M.2
  • 3
    • 0037154972 scopus 로고    scopus 로고
    • Epigenetic codes for heterochromatin formation and silencing: Rounding up the usual suspects
    • Richards E.J., Elgin S.C. Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell. 108:2002;489-500.
    • (2002) Cell , vol.108 , pp. 489-500
    • Richards, E.J.1    Elgin, S.C.2
  • 4
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • Turner B.M. Cellular memory and the histone code. Cell. 111:2002;285-291.
    • (2002) Cell , vol.111 , pp. 285-291
    • Turner, B.M.1
  • 6
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391:1998;806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 7
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • Hamilton A.J., Baulcomb D.C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science. 286:1999;950-952.
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcomb, D.C.2
  • 8
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature. 418:2002;244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 9
    • 0036532235 scopus 로고    scopus 로고
    • Heterochromatin: New possibilities for the inheritance of structure
    • Grewal S.I., Elgin S.C. Heterochromatin: new possibilities for the inheritance of structure. Curr. Opin. Genet. Dev. 12:2002;178-187.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 178-187
    • Grewal, S.I.1    Elgin, S.C.2
  • 11
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • These studies demonstrate links between the RNA interference (RNAi) pathway and heterochromatic silencing in fission yeast. RNAi components are required for the formation of silent chromatin at the mating type loci and in pericentromeric heterochromatin. Repetitive sequences in common between the two loci appear to trigger silencing via RNAi. Accumulation of transcripts from both DNA strands in heterochromatin might indicate a homeostatic mechanism for RNAi-based silencing.
    • Volpe T.A., Kidner C., Hall I.M., Teng G., Grewal S.I., Martienssen R.A. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science. 297:2002;1833-1837 These studies demonstrate links between the RNA interference (RNAi) pathway and heterochromatic silencing in fission yeast. RNAi components are required for the formation of silent chromatin at the mating type loci and in pericentromeric heterochromatin. Repetitive sequences in common between the two loci appear to trigger silencing via RNAi. Accumulation of transcripts from both DNA strands in heterochromatin might indicate a homeostatic mechanism for RNAi-based silencing.
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 12
    • 0037072660 scopus 로고    scopus 로고
    • Small RNAs correspond to centromere heterochromatic repeats
    • Reinhart B.J., Bartel D.P. Small RNAs correspond to centromere heterochromatic repeats. Science. 297:2002;1831.
    • (2002) Science , vol.297 , pp. 1831
    • Reinhart, B.J.1    Bartel, D.P.2
  • 13
    • 0035838369 scopus 로고    scopus 로고
    • Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster genome
    • Aravin A.A., Naumova N.M., Tulin A.V., Vagin V.V., Rozovsky Y.M., Gvozdev V.A. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster genome. Curr. Biol. 11:2001;1017-1027.
    • (2001) Curr. Biol. , vol.11 , pp. 1017-1027
    • Aravin, A.A.1    Naumova, N.M.2    Tulin, A.V.3    Vagin, V.V.4    Rozovsky, Y.M.5    Gvozdev, V.A.6
  • 14
    • 0036184188 scopus 로고    scopus 로고
    • RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
    • Chimeric transgenes consisting of a fusion between the white and Adh genes interact with one another and with endogenous Adh, displaying both post-transcriptional gene silencing and Polycomb-dependent transcriptional silencing. Mutations in the piwi gene, which is needed for RNA interference, interfere with both processes, suggesting that small interfering RNAs can trigger Polycomb complex formation.
    • Pal-Bhadra M., Bhadra U., Birchler J.A. RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol. Cell. 9:2002;315-327 Chimeric transgenes consisting of a fusion between the white and Adh genes interact with one another and with endogenous Adh, displaying both post-transcriptional gene silencing and Polycomb-dependent transcriptional silencing. Mutations in the piwi gene, which is needed for RNA interference, interfere with both processes, suggesting that small interfering RNAs can trigger Polycomb complex formation.
    • (2002) Mol. Cell , vol.9 , pp. 315-327
    • Pal-Bhadra, M.1    Bhadra, U.2    Birchler, J.A.3
  • 15
    • 0034596989 scopus 로고    scopus 로고
    • Transcriptional silencing and promoter methylation triggered by double-stranded RNA
    • Mette M.F., Aufsatz W., van der Winden J., Matzke M.A., Matzke A.J. Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J. 19:2000;5194-5201.
    • (2000) EMBO J. , vol.19 , pp. 5194-5201
    • Mette, M.F.1    Aufsatz, W.2    Van der Winden, J.3    Matzke, M.A.4    Matzke, A.J.5
  • 16
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M., Jenuwein T. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14:2002;286-298.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 17
    • 0035815360 scopus 로고    scopus 로고
    • Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
    • Nakayama J., Rice J.C., Strahl B.D., Allis C.D., Grewal S.I. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science. 292:2001;110-113.
    • (2001) Science , vol.292 , pp. 110-113
    • Nakayama, J.1    Rice, J.C.2    Strahl, B.D.3    Allis, C.D.4    Grewal, S.I.5
  • 18
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt H., Page A.W., Weier H.U., Bestor T.H. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell. 71:1992;865-873.
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.W.2    Weier, H.U.3    Bestor, T.H.4
  • 19
    • 0034626734 scopus 로고    scopus 로고
    • PCNA connects DNA replication to epigenetic inheritance in yeast
    • Zhang Z., Shibahara K.I., Stillman B. PCNA connects DNA replication to epigenetic inheritance in yeast. Nature. 408:2000;221-225.
    • (2000) Nature , vol.408 , pp. 221-225
    • Zhang, Z.1    Shibahara, K.I.2    Stillman, B.3
  • 20
    • 0031043134 scopus 로고    scopus 로고
    • Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I
    • Kaufman P.D., Kobayashi R., Stillman B. Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev. 11:1997;345-357.
    • (1997) Genes Dev. , vol.11 , pp. 345-357
    • Kaufman, P.D.1    Kobayashi, R.2    Stillman, B.3
  • 21
    • 0342902244 scopus 로고    scopus 로고
    • A truncated form of the human CAF-1 p150 subunit impairs the maintenance of transcriptional gene silencing in mammalian cells
    • Tchenio T., Casella J.F., Heidmann T. A truncated form of the human CAF-1 p150 subunit impairs the maintenance of transcriptional gene silencing in mammalian cells. Mol. Cell Biol. 21:2001;1953-1961.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1953-1961
    • Tchenio, T.1    Casella, J.F.2    Heidmann, T.3
  • 22
    • 0035846902 scopus 로고    scopus 로고
    • FASCIATA genes for chromatin assembly factor-1 in Arabidopsis maintain the cellular organization of apical meristems
    • Kaya H., Shibahara K.I., Taoka K.I., Iwabuchi M., Stillman B., Araki T. FASCIATA genes for chromatin assembly factor-1 in Arabidopsis maintain the cellular organization of apical meristems. Cell. 104:2001;131-142.
    • (2001) Cell , vol.104 , pp. 131-142
    • Kaya, H.1    Shibahara, K.I.2    Taoka, K.I.3    Iwabuchi, M.4    Stillman, B.5    Araki, T.6
  • 23
    • 0033212963 scopus 로고    scopus 로고
    • Heterochromatin dynamics in mouse cells: Interactions between chromatin assembly factor 1 and HP1 proteins
    • Murzina N., Verreault A., Laue E., Stillman B. Heterochromatin dynamics in mouse cells: interactions between chromatin assembly factor 1 and HP1 proteins. Mol. Cell. 4:1999;529-540.
    • (1999) Mol. Cell , vol.4 , pp. 529-540
    • Murzina, N.1    Verreault, A.2    Laue, E.3    Stillman, B.4
  • 24
    • 0033965983 scopus 로고    scopus 로고
    • The HP1 chromo shadow domain binds a consensus peptide pentamer
    • Smothers J.F., Henikoff S. The HP1 chromo shadow domain binds a consensus peptide pentamer. Curr. Biol. 10:2000;27-30.
    • (2000) Curr. Biol. , vol.10 , pp. 27-30
    • Smothers, J.F.1    Henikoff, S.2
  • 26
    • 0030272047 scopus 로고    scopus 로고
    • Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4
    • Verreault A., Kaufman P.D., Kobayashi R., Stillman B. Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell. 87:1996;95-104.
    • (1996) Cell , vol.87 , pp. 95-104
    • Verreault, A.1    Kaufman, P.D.2    Kobayashi, R.3    Stillman, B.4
  • 27
    • 0037154963 scopus 로고    scopus 로고
    • Cooperation between complexes that regulate chromatin structure and transcription
    • Narlikar G.J., Fan H.Y., Kingston R.E. Cooperation between complexes that regulate chromatin structure and transcription. Cell. 108:2002;475-487.
    • (2002) Cell , vol.108 , pp. 475-487
    • Narlikar, G.J.1    Fan, H.Y.2    Kingston, R.E.3
  • 28
    • 0035141264 scopus 로고    scopus 로고
    • The Drosophila Polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3
    • Tie F., Furuyama T., Prasad-Sinha J., Jane E., Harte P.J. The Drosophila Polycomb group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3. Development. 128:2001;275-286.
    • (2001) Development , vol.128 , pp. 275-286
    • Tie, F.1    Furuyama, T.2    Prasad-Sinha, J.3    Jane, E.4    Harte, P.J.5
  • 29
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • Czermin B., Melfi R., McCabe D., Seitz V., Imhof A., Pirrotta V. Drosophila enhancer of zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell. 111:2002;185-196.
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 32
    • 0032518442 scopus 로고    scopus 로고
    • Nucloesomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase
    • Verreault A., Kaufman P.D., Kobayashi R., Stillman B. Nucloesomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Curr. Biol. 8:1998;96-108.
    • (1998) Curr. Biol. , vol.8 , pp. 96-108
    • Verreault, A.1    Kaufman, P.D.2    Kobayashi, R.3    Stillman, B.4
  • 33
    • 0035930623 scopus 로고    scopus 로고
    • Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission yeast
    • Ahmed S., Saini S., Arora S., Singh J. Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission yeast. J. Biol. Chem. 276:2001;47814-47821.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47814-47821
    • Ahmed, S.1    Saini, S.2    Arora, S.3    Singh, J.4
  • 34
    • 0035355469 scopus 로고    scopus 로고
    • A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast
    • Nakayama J., Allshire R.C., Klar A.J., Grewal S.I. A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. EMBO J. 20:2001;2857-2866.
    • (2001) EMBO J. , vol.20 , pp. 2857-2866
    • Nakayama, J.1    Allshire, R.C.2    Klar, A.J.3    Grewal, S.I.4
  • 36
    • 0036899341 scopus 로고    scopus 로고
    • An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin
    • Chromatin remodeling complexes produce regularly spaced nucleosomal arrays in vitro, a common feature of heterochromatin. The complexes studied here reveal in vivo associations with pericentric heterochromatin only during its replication. These complexes might help the replication machinery to progress through heterochromatin, or might facilitate nucleosome assembly behind the replication fork at heterochromatic loci, or both.
    • Collins N., Poot R.A., Kukimoto I., Garcia-Jimenez C., Dellaire G., Varga-Weisz P.D. An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. Nature Genet. 32:2002;627-632 Chromatin remodeling complexes produce regularly spaced nucleosomal arrays in vitro, a common feature of heterochromatin. The complexes studied here reveal in vivo associations with pericentric heterochromatin only during its replication. These complexes might help the replication machinery to progress through heterochromatin, or might facilitate nucleosome assembly behind the replication fork at heterochromatic loci, or both.
    • (2002) Nature Genet. , vol.32 , pp. 627-632
    • Collins, N.1    Poot, R.A.2    Kukimoto, I.3    Garcia-Jimenez, C.4    Dellaire, G.5    Varga-Weisz, P.D.6
  • 38
    • 0036846539 scopus 로고    scopus 로고
    • Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha
    • Nielsen A.L., Sanchez C., Ichinose H., Cervino M., Lerouge T., Chambon P., Losson R. Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha. EMBO J. 21:2002;5797-5806.
    • (2002) EMBO J. , vol.21 , pp. 5797-5806
    • Nielsen, A.L.1    Sanchez, C.2    Ichinose, H.3    Cervino, M.4    Lerouge, T.5    Chambon, P.6    Losson, R.7
  • 40
    • 0032907728 scopus 로고    scopus 로고
    • Maintenance of genomic methylation requires a SWI2/SNF2-like protein
    • Jeddeloh J.A., Stokes T.L., Richards E.J. Maintenance of genomic methylation requires a SWI2/SNF2-like protein. Nat. Genet. 22:1999;94-97.
    • (1999) Nat. Genet. , vol.22 , pp. 94-97
    • Jeddeloh, J.A.1    Stokes, T.L.2    Richards, E.J.3
  • 41
    • 0031707751 scopus 로고    scopus 로고
    • Alteration of nucleosome structure as a mechanism of transcriptional regulation
    • Workman J.L., Kingston R.E. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem. 67:1998;545-579.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 545-579
    • Workman, J.L.1    Kingston, R.E.2
  • 42
    • 0029759928 scopus 로고    scopus 로고
    • Activator-dependent regulation of transcriptional pausing on nucleosomal templates
    • Brown S.A., Imbalzano A.N., Kingston R.E. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Genes Dev. 10:1996;1479-1490.
    • (1996) Genes Dev. , vol.10 , pp. 1479-1490
    • Brown, S.A.1    Imbalzano, A.N.2    Kingston, R.E.3
  • 43
    • 0036299092 scopus 로고    scopus 로고
    • The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly
    • 2 tetramers is a potential mechanism for introduction of active histone modifications.
    • 2 tetramers is a potential mechanism for introduction of active histone modifications.
    • (2002) Mol. Cell , vol.9 , pp. 1191-1200
    • Ahmad, K.1    Henikoff, S.2
  • 44
    • 0037143444 scopus 로고    scopus 로고
    • Interplay between two epigenetic marks: DNA methylation and histone H3 lysine 9 methylation
    • CpNpG DNA methylation depends upon histone H3-K9 methylation in Arabidopsis. Loss of DNA methylation resulted in loss of H3-K9Me, but only when transcription occurred, as if old methylated nucleosomes are replaced with new unmethylated ones in a transcription-coupled manner.
    • Johnson L.M., Cao X., Jacobsen S.E. Interplay between two epigenetic marks: DNA methylation and histone H3 lysine 9 methylation. Curr. Biol. 12:2002;1360-1367 CpNpG DNA methylation depends upon histone H3-K9 methylation in Arabidopsis. Loss of DNA methylation resulted in loss of H3-K9Me, but only when transcription occurred, as if old methylated nucleosomes are replaced with new unmethylated ones in a transcription-coupled manner.
    • (2002) Curr. Biol. , vol.12 , pp. 1360-1367
    • Johnson, L.M.1    Cao, X.2    Jacobsen, S.E.3
  • 45
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan X., Ng H.H., Johnson C.A., Laherty C.D., Turner B.M., Eisenman R.N., Bird A. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 393:1998;386-389.
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 47
    • 0034721670 scopus 로고    scopus 로고
    • The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
    • Goldmark J.P., Fazzio T.G., Estep P.W., Church G.M., Tsukiyama T. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell. 103:2000;423-433.
    • (2000) Cell , vol.103 , pp. 423-433
    • Goldmark, J.P.1    Fazzio, T.G.2    Estep, P.W.3    Church, G.M.4    Tsukiyama, T.5
  • 48
    • 0035962662 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling factors: Nucleosome shufflers with many missions
    • Varga-Weisz P.D. ATP-dependent chromatin remodeling factors: nucleosome shufflers with many missions. Oncogene. 20:2001;3076-3085.
    • (2001) Oncogene , vol.20 , pp. 3076-3085
    • Varga-Weisz, P.D.1
  • 49
    • 0033615616 scopus 로고    scopus 로고
    • Epigenetic inheritance of active chromatin after removal of the main transactivator
    • Cavalli G., Paro R. Epigenetic inheritance of active chromatin after removal of the main transactivator. Science. 286:1999;955-958.
    • (1999) Science , vol.286 , pp. 955-958
    • Cavalli, G.1    Paro, R.2
  • 50
    • 0036849525 scopus 로고    scopus 로고
    • Transcription activates repressed domains in the Drosophila bithorax complex
    • P-element insertions were isolated within a cis-regulatory region of the Drosophila bithorax complex. Remarkably, transcription initiating from the P-element promoter and extending through the regulatory regions of the silent chromatin domains as much as 50 kb away caused them to switch from silent to active during embryonic development.
    • Bender W., Fitzgerald D.P. Transcription activates repressed domains in the Drosophila bithorax complex. Development. 129:2002;4923-4930 P-element insertions were isolated within a cis-regulatory region of the Drosophila bithorax complex. Remarkably, transcription initiating from the P-element promoter and extending through the regulatory regions of the silent chromatin domains as much as 50 kb away caused them to switch from silent to active during embryonic development.
    • (2002) Development , vol.129 , pp. 4923-4930
    • Bender, W.1    Fitzgerald, D.P.2
  • 51
    • 0036848563 scopus 로고    scopus 로고
    • Transcription through the iab-7 cis-regulatory domain of the bithorax complex interferes with maintenance of Polycomb-mediated silencing
    • A test for insulator function of fragments inserted into the bithorax complex led to the fortuitous discovery that insertion of a promoter resulted in switching a cis-regulatory region from a silent to an active state. It appears that transcription through a region that normally binds repressive Polycomb complexes is sufficient to cause derepression.
    • Hogga I., Karch F. Transcription through the iab-7 cis-regulatory domain of the bithorax complex interferes with maintenance of Polycomb-mediated silencing. Development. 129:2002;4915-4922 A test for insulator function of fragments inserted into the bithorax complex led to the fortuitous discovery that insertion of a promoter resulted in switching a cis-regulatory region from a silent to an active state. It appears that transcription through a region that normally binds repressive Polycomb complexes is sufficient to cause derepression.
    • (2002) Development , vol.129 , pp. 4915-4922
    • Hogga, I.1    Karch, F.2
  • 52
    • 0036841029 scopus 로고    scopus 로고
    • Transcription through intergenic chromosomal memory elements of the Drosophila bithorax complex correlates with an epigenetic switch
    • •], suggests that intergenic transcripts within the bithorax complex normally maintain segment-specific expression early in development.
    • •], suggests that intergenic transcripts within the bithorax complex normally maintain segment-specific expression early in development.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 8026-8034
    • Rank, G.1    Prestel, M.2    Paro, R.3
  • 53
    • 0037168536 scopus 로고    scopus 로고
    • Transcription defines the embryonic domains of cis-regulatory activity at the Drosophila bithorax complex
    • Drewall R.A., Bae E., Burr J., Lewis E.B. Transcription defines the embryonic domains of cis-regulatory activity at the Drosophila bithorax complex. Proc. Natl. Acad Sci. USA. 99:2002;16853-16858.
    • (2002) Proc. Natl. Acad Sci. USA , vol.99 , pp. 16853-16858
    • Drewall, R.A.1    Bae, E.2    Burr, J.3    Lewis, E.B.4
  • 54
    • 0023332565 scopus 로고
    • Novel transcripts from the Ultrabithorax domain of the bithorax complex
    • Lipshitz H.D., Peattie D.A., Hogness D.S. Novel transcripts from the Ultrabithorax domain of the bithorax complex. Genes Dev. 3:1987;307-322.
    • (1987) Genes Dev. , vol.3 , pp. 307-322
    • Lipshitz, H.D.1    Peattie, D.A.2    Hogness, D.S.3
  • 55
    • 0036844024 scopus 로고    scopus 로고
    • The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription
    • Santoto R., Li J., Grummt I. The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat. Genet. 32:2002;393-396.
    • (2002) Nat. Genet. , vol.32 , pp. 393-396
    • Santoto, R.1    Li, J.2    Grummt, I.3
  • 56
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • in press
    • Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T: The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem 2002, in press.
    • (2002) J Biol Chem
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 57
    • 0035891265 scopus 로고    scopus 로고
    • A histone H3 methyltransferase controls DNA methylation in Neurospora crassa
    • Tamaru H., Selker E.U. A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature. 414:2001;277-283.
    • (2001) Nature , vol.414 , pp. 277-283
    • Tamaru, H.1    Selker, E.U.2
  • 58
    • 0037041422 scopus 로고    scopus 로고
    • Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
    • This study provides a link between DNA methylation and histone modification in a higher eukaryote. Non-CpG DNA methylation is reduced in the absence of the Arabidopsis KRYPTONITE (SUVH4) H3-K9Me methyltransferase. The mutants resemble loss of the CHROMOMETHYLASE3 (CMT3) CpNpG-specific methyltransferase.
    • Jackson J.P., Lindroth A.M., Cao X., Jacobsen S.E. Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature. 416:2002;556-560 This study provides a link between DNA methylation and histone modification in a higher eukaryote. Non-CpG DNA methylation is reduced in the absence of the Arabidopsis KRYPTONITE (SUVH4) H3-K9Me methyltransferase. The mutants resemble loss of the CHROMOMETHYLASE3 (CMT3) CpNpG-specific methyltransferase.
    • (2002) Nature , vol.416 , pp. 556-560
    • Jackson, J.P.1    Lindroth, A.M.2    Cao, X.3    Jacobsen, S.E.4
  • 59
    • 12244271065 scopus 로고    scopus 로고
    • An Arabidopsis SET domain protein required for maintenance but not establishment of DNA methylation
    • Mutations in the SUVH4 (KRYPTONITE) methyltransferase gene are shown to reduce non-CpG DNA methylation on singlet targets, but not on an inverted repeat homolog, in contrast to CMT3 mutations, which affect both types of targets. Double-stranded RNAs produced from the inverted repeat may target the homologous single copies, but histone methylation is needed to maintain singlet silencing (Figure 4).
    • Malagnac F., Bartee L., Bender J. An Arabidopsis SET domain protein required for maintenance but not establishment of DNA methylation. EMBO J. 21:2002;6842-6852 Mutations in the SUVH4 (KRYPTONITE) methyltransferase gene are shown to reduce non-CpG DNA methylation on singlet targets, but not on an inverted repeat homolog, in contrast to CMT3 mutations, which affect both types of targets. Double-stranded RNAs produced from the inverted repeat may target the homologous single copies, but histone methylation is needed to maintain singlet silencing (Figure 4).
    • (2002) EMBO J. , vol.21 , pp. 6842-6852
    • Malagnac, F.1    Bartee, L.2    Bender, J.3
  • 60
    • 0037474126 scopus 로고    scopus 로고
    • ARGONAUTE4 controls locus specific siRNA accumulation, DNA and histone methylation
    • A component of the RNA interference pathway is implicated in silencing of CMT3 targets, which are transcribed into 25-26 bp small interfering RNAs.
    • Zilberman D., Cao X., Jacobsen S.E. ARGONAUTE4 controls locus specific siRNA accumulation, DNA and histone methylation. Science. 299:2003;716-719 A component of the RNA interference pathway is implicated in silencing of CMT3 targets, which are transcribed into 25-26 bp small interfering RNAs.
    • (2003) Science , vol.299 , pp. 716-719
    • Zilberman, D.1    Cao, X.2    Jacobsen, S.E.3
  • 61
    • 0037039164 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3
    • -/- mutants are compared with wild type, this method reveals a distinct preference of CMT3 for methylating transposon targets.
    • -/- mutants are compared with wild type, this method reveals a distinct preference of CMT3 for methylating transposon targets.
    • (2002) Curr. Biol. , vol.12 , pp. 65-68
    • Tompa, R.1    McCallum, C.M.2    Delrow, J.3    Henikoff, J.G.4    Van Steensel, B.5    Henikoff, S.6
  • 62
    • 0025149098 scopus 로고
    • Sequence analysis of acetylation and methylation in two histone H3 variants of alfalfa
    • Waterborg J.H. Sequence analysis of acetylation and methylation in two histone H3 variants of alfalfa. J. Biol. Chem. 265:1990;17157-17161.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17157-17161
    • Waterborg, J.H.1
  • 63
    • 0030828073 scopus 로고    scopus 로고
    • Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
    • Hendzel M.J., Wei Y., Mancini M.A., Van Hooser A., Ranalli T., Brinkley B.R., Bazett-Jones D.P., Allis C.D. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 106:1997;348-360.
    • (1997) Chromosoma , vol.106 , pp. 348-360
    • Hendzel, M.J.1    Wei, Y.2    Mancini, M.A.3    Van Hooser, A.4    Ranalli, T.5    Brinkley, B.R.6    Bazett-Jones, D.P.7    Allis, C.D.8
  • 64
    • 0033639243 scopus 로고    scopus 로고
    • Phosphorylation of histone H3 correlates with transcriptionally active loci
    • Nowak S.J., Corces V.G. Phosphorylation of histone H3 correlates with transcriptionally active loci. Genes Dev. 14:2000;3003-3013.
    • (2000) Genes Dev. , vol.14 , pp. 3003-3013
    • Nowak, S.J.1    Corces, V.G.2
  • 65
    • 0036849262 scopus 로고    scopus 로고
    • Epigenetic consequences of nucleosome dynamics
    • Ahmad K., Henikoff S. Epigenetic consequences of nucleosome dynamics. Cell. 111:2002;281-284.
    • (2002) Cell , vol.111 , pp. 281-284
    • Ahmad, K.1    Henikoff, S.2
  • 66
    • 0036790591 scopus 로고    scopus 로고
    • The Drosophila BRM complex facilitates global transcription by RNA polymerase II
    • This paper shows that the Brahma (BRM) remodeling complex is associated with almost all active chromatin in fly polytene chromosomes and is required for RNA polymerase II association with chromatin. Taken together with the remarkable abundance of BRM, these findings suggest that remodeling complexes play a pivotal role in maintaining active chromatin. Although BRM is essential, its histone-tail-binding bromodomain is not, and bromodomain-less BRM still localizes normally.
    • Armstrong J.A., Papoulas O., Daubresse G., Sperling A.S., Lis J.T., Scott M.P., Tamkun J.W. The Drosophila BRM complex facilitates global transcription by RNA polymerase II. EMBO J. 21:2002;5245-5254 This paper shows that the Brahma (BRM) remodeling complex is associated with almost all active chromatin in fly polytene chromosomes and is required for RNA polymerase II association with chromatin. Taken together with the remarkable abundance of BRM, these findings suggest that remodeling complexes play a pivotal role in maintaining active chromatin. Although BRM is essential, its histone-tail-binding bromodomain is not, and bromodomain-less BRM still localizes normally.
    • (2002) EMBO J. , vol.21 , pp. 5245-5254
    • Armstrong, J.A.1    Papoulas, O.2    Daubresse, G.3    Sperling, A.S.4    Lis, J.T.5    Scott, M.P.6    Tamkun, J.W.7
  • 68
    • 0036203807 scopus 로고    scopus 로고
    • Nucleosome remodeling induced by RNA polymerase II: Loss of the H2A/H2B dimer during transcription
    • Kireeva M.L., Walter W., Tchernajenko V., Bondarenko V., Kashley M., Studitsky V.M. Nucleosome remodeling induced by RNA polymerase II: loss of the H2A/H2B dimer during transcription. Mol. Cell. 9:2002;541-552.
    • (2002) Mol. Cell , vol.9 , pp. 541-552
    • Kireeva, M.L.1    Walter, W.2    Tchernajenko, V.3    Bondarenko, V.4    Kashley, M.5    Studitsky, V.M.6
  • 69
  • 70
    • 0035102746 scopus 로고    scopus 로고
    • The hinge of and chromo shadow domain impart distinct targeting of HP1-like proteins
    • Smothers J.F., Henikoff S. The hinge of and chromo shadow domain impart distinct targeting of HP1-like proteins. Mol. Cell Biol. 21:2000;2555-2569.
    • (2000) Mol. Cell Biol. , vol.21 , pp. 2555-2569
    • Smothers, J.F.1    Henikoff, S.2
  • 71
    • 0036842221 scopus 로고    scopus 로고
    • Genome-wide DNA replication profile for Drosophila melanogaster: A link between transcription and replication timing
    • There has been much speculation that early replication correlates with gene activity, but a genome-wide mapping of replication in yeast showed that this is not the case. This first genome-wide replication map in a higher eukaryote comes to a very different conclusion. By separating early and late replicating Drosophila DNA and using microarray hybridization experiments, the authors show a strong correlation between early replication and gene activity.
    • Schubeler D., Scalzo D., Kooperberg C., van Steensel B., Delrow J., Groudine M. Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Nat. Genet. 32:2002;438-442 There has been much speculation that early replication correlates with gene activity, but a genome-wide mapping of replication in yeast showed that this is not the case. This first genome-wide replication map in a higher eukaryote comes to a very different conclusion. By separating early and late replicating Drosophila DNA and using microarray hybridization experiments, the authors show a strong correlation between early replication and gene activity.
    • (2002) Nat. Genet. , vol.32 , pp. 438-442
    • Schubeler, D.1    Scalzo, D.2    Kooperberg, C.3    Van Steensel, B.4    Delrow, J.5    Groudine, M.6
  • 72
    • 0037078986 scopus 로고    scopus 로고
    • Establishment of transcriptional competence in early and late S phase
    • DNA that is microinjected early in S phase is more abundantly transcribed than DNA injected in late S phase in mammalian cells. Early injection results in packaging of templates with hyperacetylated histones, whereas DNA injected late is packaged with hypoacetylated histones. Nucleosome assembly may use different substrates during early and late replication stages, resulting in differences in transcriptional competence.
    • Zhang J., Xu F., Hashimshony T., Keshet I., Cedar H. Establishment of transcriptional competence in early and late S phase. Nature. 420:2002;198-202 DNA that is microinjected early in S phase is more abundantly transcribed than DNA injected in late S phase in mammalian cells. Early injection results in packaging of templates with hyperacetylated histones, whereas DNA injected late is packaged with hypoacetylated histones. Nucleosome assembly may use different substrates during early and late replication stages, resulting in differences in transcriptional competence.
    • (2002) Nature , vol.420 , pp. 198-202
    • Zhang, J.1    Xu, F.2    Hashimshony, T.3    Keshet, I.4    Cedar, H.5
  • 74
    • 0037314178 scopus 로고    scopus 로고
    • Early-replicating heterochromatin
    • Kim S., Dubey D.D., Huberman J.A. Early-replicating heterochromatin. Genes Dev. 17:2003;330-335.
    • (2003) Genes Dev. , vol.17 , pp. 330-335
    • Kim, S.1    Dubey, D.D.2    Huberman, J.A.3
  • 75
    • 0037058948 scopus 로고    scopus 로고
    • Histone H3 variants specify modes of chromatin assembly
    • Ahmad K., Henikoff S. Histone H3 variants specify modes of chromatin assembly. Proc. Natl. Acad Sci. USA. 99(Suppl 4):2002;16477-16484.
    • (2002) Proc. Natl. Acad Sci. USA , vol.99 , Issue.SUPPL. 4 , pp. 16477-16484
    • Ahmad, K.1    Henikoff, S.2
  • 76
    • 0037074010 scopus 로고    scopus 로고
    • Signaling network model of chromatin
    • Schreiber S.L., Bernstein B.E. Signaling network model of chromatin. Cell. 111:2002;771-778.
    • (2002) Cell , vol.111 , pp. 771-778
    • Schreiber, S.L.1    Bernstein, B.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.