The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: Implications for unifying the heterogeneous phenotypes of NHEJ mutants

DNA Repair

Volumn 1, Issue 12, 2002, Pages 1017-1026

  Karanjawala, Zarir E ^a   Adachi, Noritaka ^a   Irvine, Ryan A ^a   Oh, Eui K ^a   Shibata, Darryl ^a   Schwarz, Klaus ^b   Hsieh, Chih Lin ^a   Lieber, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Aging; Chromosome breaks; Double strand DNA breaks; Gene rearrangement; Immunoglobulin; NHEJ; Nonhomologous DNA end joining

Indexed keywords

POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ACCELERATION; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL VIABILITY; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME DEFICIENCY; EUKARYOTE; GENE DELETION; GENETIC HETEROGENEITY; IONIZING RADIATION; LETHALITY; MAMMAL; MOUSE; MUTANT; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RADIOSENSITIVITY; SENESCENCE; T LYMPHOCYTE;

ANIMALS; ANTIGENS, NUCLEAR; CELLS, CULTURED; CHROMOSOME BREAKAGE; DNA HELICASES; DNA LIGASES; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; FETAL DEATH; HUMANS; MALE; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MUTATION; PHENOTYPE; PREGNANCY; RECOMBINATION, GENETIC;

EUKARYOTA; MAMMALIA;

EID: 0037027853     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00151-9     Document Type: Article

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