Sanguinarine causes DNA damage and p53-independent cell death in human colon cancer cell lines

Chemico-Biological Interactions

Volumn 172, Issue 1, 2008, Pages 63-71

  Matkar, Smita S ^a   Wrischnik, Lisa A ^a   Hellmann Blumberg, Utha ^a  

^a UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

8 Oxodeoxyguanosine; Apoptosis; DNA strand breaks; Oxidative DNA damage; p53; Sanguinarine

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BENZOPHENANTHRIDINE DERIVATIVE; DOUBLE STRANDED DNA; PROTEIN P53; SANGUINARINE; SINGLE STRANDED DNA; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL LINE; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG MECHANISM; HUMAN; HUMAN CELL; OXIDATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOPHENANTHRIDINES; CELL LINE, TUMOR; COLONIC NEOPLASMS; DNA DAMAGE; HUMANS; ISOQUINOLINES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 39549088303     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.12.006     Document Type: Article

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