Apoptogenic activity of two benzophenanthridine alkaloids from Chelidonium majus L. does not correlate with their DNA damaging effects

Toxicology in Vitro

Volumn 22, Issue 2, 2008, Pages 287-295

  Philchenkov, Alex ^a   Kaminskyy, Vitaliy ^b   Zavelevich, Michael ^a   Stoika, Rostyslav ^b  

^a INSTITUTE OF HYDROBIOLOGY   (Ukraine)

^b INSTITUTE OF CELL BIOLOGY   (Ukraine)

Author keywords

Apoptosis; Bax; Caspase 3; Cell cycle; Chelidonine; Cytochrome C; MT 4 cells; Sanguinarine

Indexed keywords

CASPASE 3; CASPASE 9; CHELIDONINE; CHELIDONIUM EXTRACT; CYTOCHROME C; DNA; PROTEIN BAX; SANGUINARINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHELIDONIUM; COMET ASSAY; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; MITOCHONDRION;

ALKALOIDS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOPHENANTHRIDINES; BLOTTING, WESTERN; CASPASE 9; CELL LINE, TUMOR; CELL NUCLEUS; CHELIDONIUM; COMET ASSAY; CYTOCHROMES C; DNA DAMAGE; DNA, NEOPLASM; FLOW CYTOMETRY; HUMANS; INTERCALATING AGENTS; ISOQUINOLINES; LEUKEMIA-LYMPHOMA, ADULT T-CELL;

CHELIDONIUM MAJUS; PAPAVERACEAE;

EID: 38549178993     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.08.023     Document Type: Article

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