메뉴 건너뛰기




Volumn 48, Issue 4, 2010, Pages 1117-1122

Evaluation of tolerable levels of dietary quercetin for exerting its antioxidative effect in high cholesterol-fed rats

Author keywords

Antioxidative effect; Onion; Quercetin; Tolerable level

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; QUERCETIN; QUERCETIN AGLYCONE; QUERCETIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 77549086969     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.02.005     Document Type: Article
Times cited : (35)

References (48)
  • 1
    • 0026594634 scopus 로고
    • Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species
    • Ahmed M.S., Fazal F., Rahman A., Hadi S.M., and Parish J.H. Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species. Carcinogenesis 13 (1992) 605-608
    • (1992) Carcinogenesis , vol.13 , pp. 605-608
    • Ahmed, M.S.1    Fazal, F.2    Rahman, A.3    Hadi, S.M.4    Parish, J.H.5
  • 3
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologic studies
    • Arts I.C.W., and Hollman P.C.H. Polyphenols and disease risk in epidemiologic studies. Am. J. Clin. Nutr. 81 Suppl. (2005) 317S-325S
    • (2005) Am. J. Clin. Nutr. , vol.81 , Issue.SUPPL
    • Arts, I.C.W.1    Hollman, P.C.H.2
  • 4
    • 0018092763 scopus 로고
    • High-density lipoproteins estimated by an enzymatic cholesterol procedure, with a centrifugal analyzer
    • Ash K.O., and Hentschel W.M. High-density lipoproteins estimated by an enzymatic cholesterol procedure, with a centrifugal analyzer. Clin. Chem. 24 (1978) 2180-2184
    • (1978) Clin. Chem. , vol.24 , pp. 2180-2184
    • Ash, K.O.1    Hentschel, W.M.2
  • 5
    • 0037070378 scopus 로고    scopus 로고
    • Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats
    • Azuma K., Ippoushi K., Ito H., Higashio H., and Terao J. Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats. J. Agric. Food Chem. 50 (2002) 1706-1712
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 1706-1712
    • Azuma, K.1    Ippoushi, K.2    Ito, H.3    Higashio, H.4    Terao, J.5
  • 6
    • 2642547799 scopus 로고    scopus 로고
    • Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats
    • Azuma K., Ippoushi K., Ito H., Horie H., and Terao J. Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats. Biosci. Biotechnol. Biochem. 67 (2003) 2548-2555
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 2548-2555
    • Azuma, K.1    Ippoushi, K.2    Ito, H.3    Horie, H.4    Terao, J.5
  • 7
    • 34247260351 scopus 로고    scopus 로고
    • Lowering effects of onion intake on oxidative stress biomarkers in streptozotocin-induced diabetic rats
    • Azuma K., Minami Y., Ippoushi K., and Terao J. Lowering effects of onion intake on oxidative stress biomarkers in streptozotocin-induced diabetic rats. J. Clin. Biochem. Nutr. 40 (2007) 131-140
    • (2007) J. Clin. Biochem. Nutr. , vol.40 , pp. 131-140
    • Azuma, K.1    Minami, Y.2    Ippoushi, K.3    Terao, J.4
  • 8
    • 0030661631 scopus 로고    scopus 로고
    • Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus
    • Babu P.S., and Srinivasan K. Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus. Mol. Cell. Biochem. 175 (1997) 49-57
    • (1997) Mol. Cell. Biochem. , vol.175 , pp. 49-57
    • Babu, P.S.1    Srinivasan, K.2
  • 9
    • 0032794793 scopus 로고    scopus 로고
    • Renal lesions in streptozotocin-induced diabetic rats maintained on onion and capsaicin containing diets
    • Babu P.S., and Srinivasan K. Renal lesions in streptozotocin-induced diabetic rats maintained on onion and capsaicin containing diets. J. Nutr. Biochem. 10 (1999) 477-483
    • (1999) J. Nutr. Biochem. , vol.10 , pp. 477-483
    • Babu, P.S.1    Srinivasan, K.2
  • 10
    • 36148987646 scopus 로고    scopus 로고
    • Effects of an excessive intake of quercetin on the vitamin E level and antioxidative enzyme activities of mouse liver under paraqaut-induced oxidative stress
    • Bando N., Wakamatsu S., and Terao J. Effects of an excessive intake of quercetin on the vitamin E level and antioxidative enzyme activities of mouse liver under paraqaut-induced oxidative stress. Biosci. Biotechnol. Biochem. 71 (2007) 2569-2572
    • (2007) Biosci. Biotechnol. Biochem. , vol.71 , pp. 2569-2572
    • Bando, N.1    Wakamatsu, S.2    Terao, J.3
  • 11
    • 60749133286 scopus 로고    scopus 로고
    • Lethal, sublethal, and behavioral effects of sulfur-containing products in bioassays of three species of orchard mites
    • Beers E.H., Martinez-Rocha L., Talley R.R., and Dunley J.E. Lethal, sublethal, and behavioral effects of sulfur-containing products in bioassays of three species of orchard mites. J. Econ. Entomol. 102 (2009) 324-335
    • (2009) J. Econ. Entomol. , vol.102 , pp. 324-335
    • Beers, E.H.1    Martinez-Rocha, L.2    Talley, R.R.3    Dunley, J.E.4
  • 12
    • 0001104623 scopus 로고
    • A survey of the twenty-four-hour uric acid and urea clearances in eclampsia and severe preeclampsia
    • Bonsnes R.W., and Stander H.J. A survey of the twenty-four-hour uric acid and urea clearances in eclampsia and severe preeclampsia. J. Biol. Chem. 158 (1945) 581-591
    • (1945) J. Biol. Chem. , vol.158 , pp. 581-591
    • Bonsnes, R.W.1    Stander, H.J.2
  • 13
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: from antioxidant to nutraceutical
    • Boots A.W., Haenen G.R., and Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 585 (2008) 325-337
    • (2008) Eur. J. Pharmacol. , vol.585 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 14
    • 0033760576 scopus 로고    scopus 로고
    • Absorption and DNA protective effects of flavonoid glycosides from an onion meal
    • Boyle S.P., Dobson V.L., Duthie S.J., Kyle J.A.M., and Collins A.R. Absorption and DNA protective effects of flavonoid glycosides from an onion meal. Eur. J. Nutr. 39 (2000) 213-223
    • (2000) Eur. J. Nutr. , vol.39 , pp. 213-223
    • Boyle, S.P.1    Dobson, V.L.2    Duthie, S.J.3    Kyle, J.A.M.4    Collins, A.R.5
  • 15
    • 67649372477 scopus 로고    scopus 로고
    • Evaluation of the copper(II) reduction assay using bathocuproinedisulfonic acid disodium salt for the total antioxidant capacity assessment: The CUPRAC-BCS assay
    • Campos C., Guzman R., Lopez-Fernandez E., and Casado A. Evaluation of the copper(II) reduction assay using bathocuproinedisulfonic acid disodium salt for the total antioxidant capacity assessment: The CUPRAC-BCS assay. Anal. Biochem. 392 (2009) 37-44
    • (2009) Anal. Biochem. , vol.392 , pp. 37-44
    • Campos, C.1    Guzman, R.2    Lopez-Fernandez, E.3    Casado, A.4
  • 16
    • 0345599933 scopus 로고    scopus 로고
    • Anti- and prooxidant effects of chronic quercetin administration in rats
    • Choi E.J., Chee K.M., and Lee B.H. Anti- and prooxidant effects of chronic quercetin administration in rats. Eur. J. Pharmacol. 482 (2003) 281-285
    • (2003) Eur. J. Pharmacol. , vol.482 , pp. 281-285
    • Choi, E.J.1    Chee, K.M.2    Lee, B.H.3
  • 17
    • 0037377562 scopus 로고    scopus 로고
    • Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
    • Day A.J., Gee J.M., DuPont M.S., Johnson I.T., and Williamson G. Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. Biochem. Pharmacol. 65 (2003) 1199-1206
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 1199-1206
    • Day, A.J.1    Gee, J.M.2    DuPont, M.S.3    Johnson, I.T.4    Williamson, G.5
  • 18
    • 77549088842 scopus 로고    scopus 로고
    • Evans, M.D., Olinski, R., Loft, S., Cooke, M.S., 2009. Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine as a noninvasive biomarker of oxidative stress. FASEB J. Dec. 4 [Epub ahead of print].
    • Evans, M.D., Olinski, R., Loft, S., Cooke, M.S., 2009. Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine as a noninvasive biomarker of oxidative stress. FASEB J. Dec. 4 [Epub ahead of print].
  • 19
    • 34247894012 scopus 로고    scopus 로고
    • DFT study of quercetin activated forms involved in antiradical, antioxidant, and prooxidant biological processes
    • Fiorucci S., Golebiowaki J., Cabrol-Bass D., and Antonczak S. DFT study of quercetin activated forms involved in antiradical, antioxidant, and prooxidant biological processes. J. Agric. Food Chem. 55 (2007) 903-911
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 903-911
    • Fiorucci, S.1    Golebiowaki, J.2    Cabrol-Bass, D.3    Antonczak, S.4
  • 20
    • 0029610477 scopus 로고
    • Review of the biology of quercetin and related bioflavonoids
    • Formica J.V., and Regelson W. Review of the biology of quercetin and related bioflavonoids. Food Chem. Toxicol. 33 (1995) 1061-1080
    • (1995) Food Chem. Toxicol. , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 21
    • 3042574709 scopus 로고    scopus 로고
    • Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties
    • Galati G., and O'Brien P.J. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med. 37 (2004) 287-303
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 287-303
    • Galati, G.1    O'Brien, P.J.2
  • 22
    • 0036679809 scopus 로고    scopus 로고
    • Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics
    • Galati G., Sabzevari O., Wilson J.X., and O'Brien P.J. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology 177 (2002) 91-104
    • (2002) Toxicology , vol.177 , pp. 91-104
    • Galati, G.1    Sabzevari, O.2    Wilson, J.X.3    O'Brien, P.J.4
  • 23
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: the road ahead
    • Glass C.K., and Witztum J.L. Atherosclerosis: the road ahead. Cell 104 (2001) 503-516
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 24
    • 0031020195 scopus 로고    scopus 로고
    • Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships
    • Guohua C., Sofic E., and Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radic. Biol. Med. 22 (1997) 749-760
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 749-760
    • Guohua, C.1    Sofic, E.2    Prior, R.L.3
  • 25
    • 0000994567 scopus 로고    scopus 로고
    • Oxidative stress
    • Halliwell B., and Gutteridge J.M.C. (Eds), Oxford University Press, New York
    • Halliwell B., and Gutteridge J.M.C. Oxidative stress. In: Halliwell B., and Gutteridge J.M.C. (Eds). Free Radicals in Biology and Medicine. third ed. (1999), Oxford University Press, New York 246-350
    • (1999) Free Radicals in Biology and Medicine. third ed. , pp. 246-350
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 26
    • 56249132709 scopus 로고    scopus 로고
    • Perspective on recent developments on sulfur-containing agents and hydrogen sulfide signaling
    • Jacob C., Anwar A., and Burkholz T. Perspective on recent developments on sulfur-containing agents and hydrogen sulfide signaling. Planta Med. 74 (2008) 1580-1592
    • (2008) Planta Med. , vol.74 , pp. 1580-1592
    • Jacob, C.1    Anwar, A.2    Burkholz, T.3
  • 27
    • 15844419387 scopus 로고    scopus 로고
    • Attenuation of lipid peroxidation and hyperlipidemia by quercetin glucoside in the aorta of high cholesterol-fed rabbit
    • Kamada C., da Silva E.L., Ohnishi-Kameyama M., Moon J.-H., and Terao J. Attenuation of lipid peroxidation and hyperlipidemia by quercetin glucoside in the aorta of high cholesterol-fed rabbit. Free Radic. Res. 39 (2005) 185-194
    • (2005) Free Radic. Res. , vol.39 , pp. 185-194
    • Kamada, C.1    da Silva, E.L.2    Ohnishi-Kameyama, M.3    Moon, J.-H.4    Terao, J.5
  • 29
    • 28844448258 scopus 로고    scopus 로고
    • Evaluation for safety of antioxidant chemopreventive agents
    • Kawanishi S., Oikawa S., and Murata M. Evaluation for safety of antioxidant chemopreventive agents. Antioxid. Redox Signal 7 (2005) 1728-1739
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 1728-1739
    • Kawanishi, S.1    Oikawa, S.2    Murata, M.3
  • 30
    • 0028316853 scopus 로고
    • Reestimation of aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio based on JSCC consensus method - changes of criteria for a differential diagnosis of hepatic disorders following the alteration from Karmen method to JSCC method
    • Kotani K., Maekawa M., and Kanno T. Reestimation of aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio based on JSCC consensus method - changes of criteria for a differential diagnosis of hepatic disorders following the alteration from Karmen method to JSCC method. Nippon Shokakibyo Gakkai Zasshi 91 (1994) 154-161
    • (1994) Nippon Shokakibyo Gakkai Zasshi , vol.91 , pp. 154-161
    • Kotani, K.1    Maekawa, M.2    Kanno, T.3
  • 31
    • 3142709948 scopus 로고    scopus 로고
    • Bioactive compounds in nutrition and health-research methodologies for establishing biological functions: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis
    • Kris-Etherton P.M., Lefevre M., Beecher G.R., Gross M.D., Keen C.L., and Etherton T.D. Bioactive compounds in nutrition and health-research methodologies for establishing biological functions: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis. Ann. Rev. Nutr. 24 (2004) 511-538
    • (2004) Ann. Rev. Nutr. , vol.24 , pp. 511-538
    • Kris-Etherton, P.M.1    Lefevre, M.2    Beecher, G.R.3    Gross, M.D.4    Keen, C.L.5    Etherton, T.D.6
  • 32
    • 0036909108 scopus 로고    scopus 로고
    • Review article: oxidative stress as a pathogenic factor in inflammatory bowel disease - radicals or ridiculous?
    • Kruidenier L., and Verspaget H.W. Review article: oxidative stress as a pathogenic factor in inflammatory bowel disease - radicals or ridiculous?. Aliment Pharmacol. Ther. 16 (2002) 1997-2015
    • (2002) Aliment Pharmacol. Ther. , vol.16 , pp. 1997-2015
    • Kruidenier, L.1    Verspaget, H.W.2
  • 33
    • 1642323567 scopus 로고    scopus 로고
    • Quercetin allievates oxidative stress in streptozotocin-induced diabetic rats
    • Mahesh T., and Menon V.P. Quercetin allievates oxidative stress in streptozotocin-induced diabetic rats. Phytother. Res. 18 (2004) 123-127
    • (2004) Phytother. Res. , vol.18 , pp. 123-127
    • Mahesh, T.1    Menon, V.P.2
  • 34
    • 0345148810 scopus 로고    scopus 로고
    • Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal products
    • Metodiewa D., Jaiswal A.K., Cenas N., Dickancaite E., and Segura-Aguilar J. Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal products. Free Radic. Biol. Med. 26 (1999) 107-116
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 107-116
    • Metodiewa, D.1    Jaiswal, A.K.2    Cenas, N.3    Dickancaite, E.4    Segura-Aguilar, J.5
  • 35
    • 0034851475 scopus 로고    scopus 로고
    • Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
    • Miean K.H., and Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem. 49 (2001) 3106-3112
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 3106-3112
    • Miean, K.H.1    Mohamed, S.2
  • 37
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H., Carney D., and Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist. Update 7 (2004) 97-110
    • (2004) Drug Resist. Update , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 38
    • 0000647819 scopus 로고    scopus 로고
    • Effect of storage and domestic processing on the content and composition of flavonol glucosides in onion (Allium cepa L.)
    • Price K.R., Bacon J.R., and Rhodes J.C. Effect of storage and domestic processing on the content and composition of flavonol glucosides in onion (Allium cepa L.). J. Agric. Food Chem. 45 (1997) 938-942
    • (1997) J. Agric. Food Chem. , vol.45 , pp. 938-942
    • Price, K.R.1    Bacon, J.R.2    Rhodes, J.C.3
  • 39
    • 0026687452 scopus 로고
    • Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals and biological consequence of scission
    • Rahman A., Fazal F., Greensill J., Ainley K., Parish J.H., and Hadi S.M. Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals and biological consequence of scission. Mol. Cell Biochem. 111 (1992) 3-9
    • (1992) Mol. Cell Biochem. , vol.111 , pp. 3-9
    • Rahman, A.1    Fazal, F.2    Greensill, J.3    Ainley, K.4    Parish, J.H.5    Hadi, S.M.6
  • 40
  • 41
    • 0034993878 scopus 로고    scopus 로고
    • Effects of quercetin on antioxidant defense in streptozotocin-induced diabetic rats
    • Sanders R.A., Rauscher F.M., and Watkins J.B. Effects of quercetin on antioxidant defense in streptozotocin-induced diabetic rats. J. Biochem. Mol. Toxicol. 15 (2001) 143-149
    • (2001) J. Biochem. Mol. Toxicol. , vol.15 , pp. 143-149
    • Sanders, R.A.1    Rauscher, F.M.2    Watkins, J.B.3
  • 42
    • 0033795879 scopus 로고    scopus 로고
    • Potential health impacts of excessive flavonoid intake
    • Skibola C.F., and Smith M.T. Potential health impacts of excessive flavonoid intake. Free Radic. Biol. Med. 29 (2000) 375-383
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 375-383
    • Skibola, C.F.1    Smith, M.T.2
  • 44
    • 33846138986 scopus 로고    scopus 로고
    • A comparison of arteries and veins in oxidative stress: products, destroyers, function, and disease
    • Szasz T., Thakali K., Fink G.D., and Watts S.W. A comparison of arteries and veins in oxidative stress: products, destroyers, function, and disease. Exp. Biol. Med. (Maywood) 232 (2007) 27-37
    • (2007) Exp. Biol. Med. (Maywood) , vol.232 , pp. 27-37
    • Szasz, T.1    Thakali, K.2    Fink, G.D.3    Watts, S.W.4
  • 45
    • 67650267213 scopus 로고    scopus 로고
    • Dietary flavonoids as antioxidants
    • T. Yoshikawa Ed
    • Terao, J., 2009a. Dietary flavonoids as antioxidants. In: T. Yoshikawa (Ed.), Food factors for health promotion. Forum Nutr. 61, 87-94.
    • (2009) Food factors for health promotion. Forum Nutr , vol.61 , pp. 87-94
    • Terao, J.1
  • 46
    • 77549087040 scopus 로고    scopus 로고
    • Flavonols: metabolism, bioavailability, and health impacts
    • Fraga C.G. (Ed), John Wiley & Sons, Inc., Hoboken, New Jersey
    • Terao J. Flavonols: metabolism, bioavailability, and health impacts. In: Fraga C.G. (Ed). Plant Phenolics and Human Health, Biochemistry, Nutrition, and Pharmacology (2009), John Wiley & Sons, Inc., Hoboken, New Jersey 185-196
    • (2009) Plant Phenolics and Human Health, Biochemistry, Nutrition, and Pharmacology , pp. 185-196
    • Terao, J.1
  • 47
    • 0000576030 scopus 로고    scopus 로고
    • Content of flavonol glucosides and some properties of enzymes metabolizing the glucosides in onion
    • Tsushida T., and Suzuki M. Content of flavonol glucosides and some properties of enzymes metabolizing the glucosides in onion. Nippon Shokuhin Kagaku Kogaku Kaishi 43 (1996) 642-649
    • (1996) Nippon Shokuhin Kagaku Kogaku Kaishi , vol.43 , pp. 642-649
    • Tsushida, T.1    Suzuki, M.2
  • 48
    • 0033846534 scopus 로고    scopus 로고
    • Cellular uptake of dietary flavonoid quercetin 4′-beta-glucoside by sodium-dependent glucose transporter SGLT1
    • Walgren R.A., Lin J.T., Kinne R.K., and Walle T. Cellular uptake of dietary flavonoid quercetin 4′-beta-glucoside by sodium-dependent glucose transporter SGLT1. J. Pharmacol. Exp. Ther. 294 (2000) 837-843
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 837-843
    • Walgren, R.A.1    Lin, J.T.2    Kinne, R.K.3    Walle, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.