메뉴 건너뛰기




Volumn 134, Issue 2, 1996, Pages 269-278

Signal sequences specify the targeting route to the endoplasmic reticulum membrane

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN PRECURSOR; SIGNAL PEPTIDE; SIGNAL RECOGNITION PARTICLE;

EID: 0029952547     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.134.2.269     Document Type: Article
Times cited : (389)

References (42)
  • 1
    • 0023607313 scopus 로고
    • Translocation in yeast and mammalian cells: Not all signal sequences are functionally equivalent
    • Bird, P., M.J. Gething, and J. Sambrook. 1987. Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent. J. Cell Biol. 105:2905-2914.
    • (1987) J. Cell Biol. , vol.105 , pp. 2905-2914
    • Bird, P.1    Gething, M.J.2    Sambrook, J.3
  • 2
    • 0023177257 scopus 로고
    • Yeast carboxypeptidase Y can be translocated and glycosylated without its amino-terminal signal sequence
    • Blachly-Dyson, E., and T.H. Stevens. 1987. Yeast carboxypeptidase Y can be translocated and glycosylated without its amino-terminal signal sequence. J. Cell Biol. 104:1183-1191.
    • (1987) J. Cell Biol. , vol.104 , pp. 1183-1191
    • Blachly-Dyson, E.1    Stevens, T.H.2
  • 3
    • 0028893336 scopus 로고
    • Isolation of a mouse cDNA encoding MTJ1, a new murine member of the DnaJ family of proteins
    • Brightman, S.E., G.L. Blatch, and B.R. Zetter. 1995. Isolation of a mouse cDNA encoding MTJ1, a new murine member of the DnaJ family of proteins. Gene (Amst.). 153:249-254.
    • (1995) Gene (Amst.) , vol.153 , pp. 249-254
    • Brightman, S.E.1    Blatch, G.L.2    Zetter, B.R.3
  • 4
    • 0027759380 scopus 로고
    • A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome
    • Brodsky, J.L., and R. Schekman. 1993. A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J. Cell Biol. 123:1355-1363.
    • (1993) J. Cell Biol. , vol.123 , pp. 1355-1363
    • Brodsky, J.L.1    Schekman, R.2
  • 5
    • 0027498031 scopus 로고
    • Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70
    • Brodsky, J.L., S. Hamamoto, D. Feldheim, and R. Schekman. 1993. Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70. J. Cell Biol. 120:95-102.
    • (1993) J. Cell Biol. , vol.120 , pp. 95-102
    • Brodsky, J.L.1    Hamamoto, S.2    Feldheim, D.3    Schekman, R.4
  • 7
    • 0027961075 scopus 로고
    • The functioning of the yeast Golgi apparatus requires an ER protein encoded by ANPI, a member of a new family of genes affecting the secretory pathway
    • Chapman, R.E., and S. Munro. 1994. The functioning of the yeast Golgi apparatus requires an ER protein encoded by ANPI, a member of a new family of genes affecting the secretory pathway. EMBO (Eur. Mol. Biol. Organ.) J. 13: 4896-4907.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 4896-4907
    • Chapman, R.E.1    Munro, S.2
  • 8
    • 0023645034 scopus 로고
    • Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins
    • Cornette, J.L., K.B. Cease, H. Margalit, J.L. Spouge, J.A. Berzofsky, and C. Delisi. 1987. Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins. J. Mol. Biol. 195:659-685.
    • (1987) J. Mol. Biol. , vol.195 , pp. 659-685
    • Cornette, J.L.1    Cease, K.B.2    Margalit, H.3    Spouge, J.L.4    Berzofsky, J.A.5    Delisi, C.6
  • 9
    • 0027457077 scopus 로고
    • A signal sequence is not required for protein export in prlA mutants of Escherichia coli
    • Derman, A.I., J.W. Puziss, P.J. Bassford, and J. Beckwith. 1993. A signal sequence is not required for protein export in prlA mutants of Escherichia coli. EMBO (Eur. Mol. Biol. Organ.) J. 12:879-888.
    • (1993) EMBO (Eur. Mol. Biol. Organ.) J. , vol.12 , pp. 879-888
    • Derman, A.I.1    Puziss, J.W.2    Bassford, P.J.3    Beckwith, J.4
  • 10
    • 0023567026 scopus 로고
    • A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum
    • Deshaies, R.J., and R. Schekman. 1987. A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J. Cell Biol. 105:633-645.
    • (1987) J. Cell Biol. , vol.105 , pp. 633-645
    • Deshaies, R.J.1    Schekman, R.2
  • 11
    • 0024828302 scopus 로고
    • SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum
    • Deshaies, R.J., and R. Schekman. 1989. SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum. J. Cell Biol. 109:2653-2664.
    • (1989) J. Cell Biol. , vol.109 , pp. 2653-2664
    • Deshaies, R.J.1    Schekman, R.2
  • 12
    • 0025059480 scopus 로고
    • Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery
    • Deshaies, R.J., and R. Schekman. 1990. Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery. Mol. Cell. Biol. 10:6024-6035.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6024-6035
    • Deshaies, R.J.1    Schekman, R.2
  • 13
    • 0028022701 scopus 로고
    • Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex
    • Feldheim, D., and R. Schekman. 1994. Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex. J. Cell Biol. 126:935-943.
    • (1994) J. Cell Biol. , vol.126 , pp. 935-943
    • Feldheim, D.1    Schekman, R.2
  • 14
    • 0027507707 scopus 로고
    • Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum
    • Feldheim, D., K. Yoshimura, A. Admon, and R. Schekman. 1993. Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum. Mol. Biol. Cell. 4:931-939.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 931-939
    • Feldheim, D.1    Yoshimura, K.2    Admon, A.3    Schekman, R.4
  • 15
    • 0029881380 scopus 로고    scopus 로고
    • A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae
    • Finke, K., K. Plath, S. Panzner, S. Prehn, T.A. Rapoport, E. Hartmann, and T. Sommer. 1996. A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. EMBO (Eur. Mol. Biol. Organ.) J. 15:1482-1494.
    • (1996) EMBO (Eur. Mol. Biol. Organ.) J. , vol.15 , pp. 1482-1494
    • Finke, K.1    Plath, K.2    Panzner, S.3    Prehn, S.4    Rapoport, T.A.5    Hartmann, E.6    Sommer, T.7
  • 16
    • 0027424601 scopus 로고
    • Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane
    • Görlich, D., and T.A. Rapoport. 1993. Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell. 75:615-630.
    • (1993) Cell , vol.75 , pp. 615-630
    • Görlich, D.1    Rapoport, T.A.2
  • 17
    • 0026466143 scopus 로고
    • A mammalian homolog of Sec61p and SecYp is associated with ribosomes and nascent polypeptides during translocalion
    • Görlich, D., S. Prehn, E. Hartmann, K.-U. Kalies, and T.A. Rapoport. 1992. A mammalian homolog of Sec61p and SecYp is associated with ribosomes and nascent polypeptides during translocalion. Cell. 71:489-503.
    • (1992) Cell , vol.71 , pp. 489-503
    • Görlich, D.1    Prehn, S.2    Hartmann, E.3    Kalies, K.-U.4    Rapoport, T.A.5
  • 18
    • 0026531641 scopus 로고
    • Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae
    • Green, N., H. Fang, and P. Walter. 1992. Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae. J. Cell Biol. 116:597-604.
    • (1992) J. Cell Biol. , vol.116 , pp. 597-604
    • Green, N.1    Fang, H.2    Walter, P.3
  • 19
    • 0024841329 scopus 로고
    • Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth
    • Hann, B.C., M.A. Poritz, and P. Walter. 1989. Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth. J. Cell Biol. 109:3223-3230.
    • (1989) J. Cell Biol. , vol.109 , pp. 3223-3230
    • Hann, B.C.1    Poritz, M.A.2    Walter, P.3
  • 20
    • 0025949923 scopus 로고
    • The signal recognition particle in S. cerevisiae
    • Hann, B.C., and P. Walter. 1991. The signal recognition particle in S. cerevisiae. Cell. 67:131-144.
    • (1991) Cell , vol.67 , pp. 131-144
    • Hann, B.C.1    Walter, P.2
  • 21
    • 0023045298 scopus 로고
    • In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent post-translational translocation of the prepro-α factor
    • Hansen, W., P.D. Garcia, and P. Walter. 1986. In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent post-translational translocation of the prepro-α factor. Cell. 45:397-406.
    • (1986) Cell , vol.45 , pp. 397-406
    • Hansen, W.1    Garcia, P.D.2    Walter, P.3
  • 22
    • 0029096050 scopus 로고
    • A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane
    • Jungnickel, B., and T.A. Rapoport. 1995. A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell. 82:261-270.
    • (1995) Cell , vol.82 , pp. 261-270
    • Jungnickel, B.1    Rapoport, T.A.2
  • 23
    • 0023088363 scopus 로고
    • Many random sequences functionally replace the secretion signal sequence of yeast invertase
    • Kaiser, C.A., D. Preuss, P. Grisafi, and D. Botstein. 1987. Many random sequences functionally replace the secretion signal sequence of yeast invertase. Science (Wash. DC.). 235:312-317.
    • (1987) Science (Wash. DC.) , vol.235 , pp. 312-317
    • Kaiser, C.A.1    Preuss, D.2    Grisafi, P.3    Botstein, D.4
  • 24
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte, J., and R.F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105-132.
    • (1982) J. Mol. Biol. , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 25
    • 0025855390 scopus 로고
    • Glycosylation site binding protein and protein disulfide isomerase are identical and essential for cell viability in yeast
    • LaMantia, M., T. Miura, H. Tachikawa, H.A. Kaplan, W.J. Lennarz, and T. Mizunaga. 1991. Glycosylation site binding protein and protein disulfide isomerase are identical and essential for cell viability in yeast. Proc. Natl. Acad. Sci. USA. 88:4453-4457.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4453-4457
    • LaMantia, M.1    Miura, T.2    Tachikawa, H.3    Kaplan, H.A.4    Lennarz, W.J.5    Mizunaga, T.6
  • 26
    • 0026657841 scopus 로고
    • MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria
    • Maarse, A.C., J. Blom, L.A. Grivell, and M. Meijer. 1992. MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria. EMBO (Eur. Mol. Biol. Organ.) J. 11:3619-3628.
    • (1992) EMBO (Eur. Mol. Biol. Organ.) J. , vol.11 , pp. 3619-3628
    • Maarse, A.C.1    Blom, J.2    Grivell, L.A.3    Meijer, M.4
  • 27
    • 0000632797 scopus 로고
    • TnphoA: Atransposon probe for protein export signals
    • Manoil, C., and J. Beckwith. 1985. TnphoA: atransposon probe for protein export signals. Proc. Natl. Acad. Sci. USA. 82:8129-8133.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8129-8133
    • Manoil, C.1    Beckwith, J.2
  • 28
    • 0030051440 scopus 로고    scopus 로고
    • ER membrane protein complex required for nuclear fusion
    • Ng, D.T.W., and P. Walter. 1996. ER membrane protein complex required for nuclear fusion. J. Cell Biol. 132:499-509.
    • (1996) J. Cell Biol. , vol.132 , pp. 499-509
    • Ng, D.T.W.1    Walter, P.2
  • 29
    • 0027967458 scopus 로고
    • A Sec62p-related component of the secretory protein translocon from Drosophila displays developmentally complex behavior
    • Noel, P., and I.L. Cartwright. 1994. A Sec62p-related component of the secretory protein translocon from Drosophila displays developmentally complex behavior. EMBO (Eur. Mol. Biol. Organ.) J. 13:5253-5261.
    • (1994) EMBO (Eur. Mol. Biol. Organ.) J. , vol.13 , pp. 5253-5261
    • Noel, P.1    Cartwright, I.L.2
  • 30
    • 0026057813 scopus 로고
    • Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane
    • Nuoffer, C., P. Jeno, A. Conzelmann, and H. Riezman. 1991. Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol. Cell. Biol. 11:27-37.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 27-37
    • Nuoffer, C.1    Jeno, P.2    Conzelmann, A.3    Riezman, H.4
  • 31
    • 0029068214 scopus 로고
    • SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation
    • Ogg, S.C., and P. Walter. 1995. SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation. Cell. 81:1075-1084.
    • (1995) Cell , vol.81 , pp. 1075-1084
    • Ogg, S.C.1    Walter, P.2
  • 32
    • 0027057308 scopus 로고
    • The signal recognition particle receptor is important for growth and protein secretion in Saccharomyces cerevisiae
    • Ogg, S., M. Poritz, and P. Walter. 1992. The signal recognition particle receptor is important for growth and protein secretion in Saccharomyces cerevisiae. Mol. Biol. Cell. 3:895-911.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 895-911
    • Ogg, S.1    Poritz, M.2    Walter, P.3
  • 33
    • 0028997459 scopus 로고
    • Post-translational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p
    • Panzner, S., L. Dreier, E. Hartmann, S. Kostka, and T.A. Rapoport. 1995. Post-translational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell. 81:561-570.
    • (1995) Cell , vol.81 , pp. 561-570
    • Panzner, S.1    Dreier, L.2    Hartmann, E.3    Kostka, S.4    Rapoport, T.A.5
  • 34
    • 0029952518 scopus 로고    scopus 로고
    • Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes
    • In Press
    • Rapoport, T.A., B. Jungnickel, and U. Kutay. 1996. Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annu. Rev. Biochem. In Press.
    • (1996) Annu. Rev. Biochem.
    • Rapoport, T.A.1    Jungnickel, B.2    Kutay, U.3
  • 35
    • 0006514917 scopus 로고
    • Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast
    • Rothblatt, J.A., R.J. Deshaies, S.L. Sanders, G. Daum, and R. Schekman. 1989. Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J. Cell Biol. 72:61-68.
    • (1989) J. Cell Biol. , vol.72 , pp. 61-68
    • Rothblatt, J.A.1    Deshaies, R.J.2    Sanders, S.L.3    Daum, G.4    Schekman, R.5
  • 36
    • 0025006519 scopus 로고
    • A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes
    • Schlenstedt, G., G.H. Gudmundsson, H.G. Boman, and R. Zimmermann. 1990. A large presecretory protein translocates both cotranslationally, using signal recognition particle and ribosome, and post-translationally, without these ribonucleoparticles, when synthesized in the presence of mammalian microsomes. J. Biol. Chem. 265:13960-13968.
    • (1990) J. Biol. Chem. , vol.265 , pp. 13960-13968
    • Schlenstedt, G.1    Gudmundsson, G.H.2    Boman, H.G.3    Zimmermann, R.4
  • 37
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R.S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 38
    • 0027058051 scopus 로고
    • Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum
    • Stirling, C.J., J. Rothblatt, M. Hosobuchi, R. Deshaies, and R. Schekman. 1992. Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol. Biol. Cell. 3:129-142.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 129-142
    • Stirling, C.J.1    Rothblatt, J.2    Hosobuchi, M.3    Deshaies, R.4    Schekman, R.5
  • 39
    • 0021856417 scopus 로고
    • Signal sequences. The limits of variation
    • von Heijne, G. 1985. Signal sequences. The limits of variation. J. Mol. Biol. 184: 99-105.
    • (1985) J. Mol. Biol. , vol.184 , pp. 99-105
    • Heijne, G.1
  • 40
    • 0025297583 scopus 로고
    • The signal peptide
    • von Heijne, G. 1990. The signal peptide. J. Membr. Biol. 115:195-201.
    • (1990) J. Membr. Biol. , vol.115 , pp. 195-201
    • Von Heijne, G.1
  • 41
    • 0028170807 scopus 로고
    • Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane
    • Walter, P., and A.E. Johnson. 1994. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu. Rev. Cell Biol. 10: 87-119.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 87-119
    • Walter, P.1    Johnson, A.E.2
  • 42
    • 0028365369 scopus 로고
    • From the elephant to E. coli: SRP-dependent protein targeting
    • Wolin, S.L. 1994. From the elephant to E. coli: SRP-dependent protein targeting. Cell. 77:787-790.
    • (1994) Cell , vol.77 , pp. 787-790
    • Wolin, S.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.