Yeast mutant with efficient secretion identified by a novel secretory reporter, Cluc

Biochemical and Biophysical Research Communications

Volumn 358, Issue 2, 2007, Pages 429-434

  Kanjou, Naoko ^a   Nagao, Aki ^a   Ohmiya, Yoshihiro ^b   Ohgiya, Satoru ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

C. noctiluca secretory luciferase (Cluc); Screening of yeast secretory strains; Secretory bioluminescence reporter enzyme

Indexed keywords

CYPRIDINA NOCTILUCA SECRETORY LUCIFERASE; ENZYME; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYPRIDINA NOCTILUCA; DELETION MUTANT; ENZYME RELEASE; EXTRACELLULAR SPACE; FUNGAL STRAIN; GENE; GOLGI COMPLEX; MON2 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SCREENING; SENSITIVITY ANALYSIS; YEAST;

ANIMALS; CYPRINIDAE; GENES, REPORTER; GENETIC ENHANCEMENT; LUCIFERASES; MUTATION; PROTEIN ENGINEERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

CYPRIDINA NOCTILUCA; SACCHAROMYCES CEREVISIAE;

EID: 34248566979     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.140     Document Type: Article

References (17)

1. Shuster J.R. Gene expression in yeast: protein secretion. Curr. Opin. Biotechnol. 2 (1991) 685-690
2. Mattanovich D., Gasser B., Hohenblum H., and Sauer M. Stress in recombinant protein producing yeasts. J. Biotechnol. 113 (2004) 121-135
3. Wang B.D., Chen D.C., and Kuo T.T. Characterization of a Saccharomyces cerevisiae mutant with oversecretion phenotype. Appl. Microbiol. Biotechnol. 55 (2001) 712-720
4. Copley K.S., Alm S.M., Schooley D.A., and Courchesne W.E. Expression, processing and secretion of a proteolytically-sensitive insect diuretic hormone by Saccharomyces cerevisiae requires the use of a yeast strain lacking genes encoding the Yap3 and Mkc7 endoproteases found in the secretory pathway. Biochem. J. 330 Pt 3 (1998) 1333-1340
5. Teichert U., Mechler B., Muller H., and Wolf D.H. Lysosomal (vacuolar) proteinases of yeast are essential catalysts for protein degradation, differentiation, and cell survival. J. Biol. Chem. 264 (1989) 16037-16045
6. Avaro S., Belgareh-Touze N., Sibella-Arguelles C., Volland C., and Haguenauer-Tsapis R. Mutants defective in secretory/vacuolar pathways in the EUROFAN collection of yeast disruptants. Yeast 19 (2002) 351-371
7. Nakajima Y., Kobayashi K., Yamagishi K., Enomoto T., and Ohmiya Y. cDNA cloning and characterization of a secreted luciferase from the luminous Japanese ostracod, Cypridina noctiluca. Biosci. Biotechnol. Biochem. 68 (2004) 565-570
8. Thompson E.M., Nagata S., and Tsuji F.I. Vargula hilgendorfii luciferase: a secreted reporter enzyme for monitoring gene expression in mammalian cells. Gene 96 (1990) 257-262
9. Harvey E.N. Bioluminescence: evolution and comparative biochemistry. Fed. Proc. 12 (1953) 597-606
10. B.J. Bryan, and C.S. Szent-Gyorgyi, May 2001. U.S. Patent 6232107.
11. Gillingham A.K., Whyte J.R., Panic B., and Munro S. MON2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. J. Biol. Chem. 281 (2006) 2273-2280
12. Efe J.A., Plattner F., Hulo N., Kressler D., Emr S.D., and Deloche O. Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis. J. Cell. Sci. 118 (2005) 4751-4764
13. Adams A., Gottschling D.E., Kaiser C.A., and Stearns T. Methods in Yeast Genetics (1997), Cold Spring Harbor Laboratory Press, New York
14. Kim J., Kamada Y., Stromhaug P.E., Guan J., Hefner-Gravink A., Baba M., Scott S.V., Ohsumi Y., Dunn Jr. W.A., and Klionsky D.J. Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. J. Cell. Biol. 153 (2001) 381-396
15. Gething M.J. Role and regulation of the ER chaperone BiP. Semin. Cell. Dev. Biol. 10 (1999) 465-472
16. Spear E.D., and Ng D.T. Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways. Mol. Biol. Cell 14 (2003) 2756-2767
17. Yamagishi K., Enomoto T., and Ohmiya Y. Perfusion-culture-based secreted bioluminescence reporter assay in living cells. Anal. Biochem. 354 (2006) 15-21