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Volumn 57, Issue 2, 1998, Pages 245-249

Simple approach to reducing proteolysis during secretary production of human parathyroid hormone in Saccharomyces cerevisiae

Author keywords

Human parathyroid hormone; KEX2 endoproteinase; L arginine; Proteolysis; Secretory production

Indexed keywords

ANIMAL CELL CULTURE; BIOSYNTHESIS; CATALYST ACTIVITY; ENZYMES; HORMONES; YEAST;

EID: 0038605296     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19980120)57:2<245::AID-BIT14>3.0.CO;2-F     Document Type: Article
Times cited : (30)

References (18)
  • 1
    • 0028046767 scopus 로고
    • Optimization of expression system using galactose inducible promoter for the production of anticoagulant hirudin in Saccharomyces cerevisiae
    • Choi, E. S., Sohn, J. H., Rhee, S. K. 1994. Optimization of expression system using galactose inducible promoter for the production of anticoagulant hirudin in Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 42: 587-594.
    • (1994) Appl. Microbiol. Biotechnol. , vol.42 , pp. 587-594
    • Choi, E.S.1    Sohn, J.H.2    Rhee, S.K.3
  • 2
    • 0006591732 scopus 로고
    • Effect of galactose feeding strategy on heterologous human lipocortin-I production in the fed-batch culture of Saccharomyces cerevisiae controlled by the GAL10 promoter
    • Chung, B. H., Kim, B. M., Rhee, S. K., Park, Y. H., Nam, S. W. 1995. Effect of galactose feeding strategy on heterologous human lipocortin-I production in the fed-batch culture of Saccharomyces cerevisiae controlled by the GAL10 promoter. J. Microbiol. Biotechnol. 5: 224-228.
    • (1995) J. Microbiol. Biotechnol. , vol.5 , pp. 224-228
    • Chung, B.H.1    Kim, B.M.2    Rhee, S.K.3    Park, Y.H.4    Nam, S.W.5
  • 3
    • 0000816913 scopus 로고
    • The Saccharomyces cerevisiae KEX2 gene, required for processing prepro-α-factor, encodes a calcium-dependent endopeptidase that cleaves after Lys-Arg and Arg-Arg sequences
    • L. Leive (ed.). American Society for Microbiology, Washington, D.C.
    • Fuller, R. S., Brake, A., Thorner, J. 1986. The Saccharomyces cerevisiae KEX2 gene, required for processing prepro-α-factor, encodes a calcium-dependent endopeptidase that cleaves after Lys-Arg and Arg-Arg sequences, pp. 273-278. In: L. Leive (ed.), Microbiology - 1986. American Society for Microbiology, Washington, D.C.
    • (1986) Microbiology - 1986 , pp. 273-278
    • Fuller, R.S.1    Brake, A.2    Thorner, J.3
  • 4
    • 0023838558 scopus 로고
    • Enzymes required for yeast prohormone processing
    • Fuller, R. S., Sterne, R. E., Thorner, J. 1988. Enzymes required for yeast prohormone processing. Annu. Rev. Physiol. 50: 345-362.
    • (1988) Annu. Rev. Physiol. , vol.50 , pp. 345-362
    • Fuller, R.S.1    Sterne, R.E.2    Thorner, J.3
  • 6
    • 0027269643 scopus 로고
    • Studies on the production of human parathyroid hormone by recombinant Escherichia coli
    • Harder, M. P. R. Sanders, E. A., Wingender, E., Deckwer, W. D. 1993. Studies on the production of human parathyroid hormone by recombinant Escherichia coli. Appl. Microbiol. Biotechnol. 39: 329-334.
    • (1993) Appl. Microbiol. Biotechnol. , vol.39 , pp. 329-334
    • Harder, M.P.R.1    Sanders, E.A.2    Wingender, E.3    Deckwer, W.D.4
  • 7
    • 0000474852 scopus 로고
    • Biased codon usage: An exploration of its role in optimization of translation
    • W. Reznikoff and L. Gold (eds.). Butterworths, Boston
    • Herman, A. B., Rob., A. K. 1986. Biased codon usage: An exploration of its role in optimization of translation, pp. 225-285. In: W. Reznikoff and L. Gold (eds.), Maximizing gene expression. Butterworths, Boston.
    • (1986) Maximizing Gene Expression , pp. 225-285
    • Herman, A.B.1    Rob, A.K.2
  • 8
    • 0021713896 scopus 로고
    • Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast pre-pro-α-factor
    • Julius, D., Brake, A., Blair, L., Kunisawa, R., Thorner, J. 1984. Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast pre-pro-α-factor. Cell 37: 1075-1089.
    • (1984) Cell , vol.37 , pp. 1075-1089
    • Julius, D.1    Brake, A.2    Blair, L.3    Kunisawa, R.4    Thorner, J.5
  • 10
    • 0020700484 scopus 로고
    • Regulation of kidney functions by hormones: A new approach
    • R. O. Grrep (ed.). Academic Press, New York
    • Morel, F. 1983. Regulation of kidney functions by hormones: A new approach, pp. 271-304, In: R. O. Grrep (ed.), Recent progress in hormone research, vol. 39. Academic Press, New York.
    • (1983) Recent Progress in Hormone Research , vol.39 , pp. 271-304
    • Morel, F.1
  • 11
    • 0026557621 scopus 로고
    • Isolation and characterization of two biologically active O-glycosylated forms of human parathyroid hormone produced in Saccharomyces cerevisiae: Identification of a new motif for O-glycosylation
    • Olstad, O. K., Reppe, S., Gabrielsen, O. S., Hartmanis, M., Blingsmo, O. R., Gautvik, V. T. 1992. Isolation and characterization of two biologically active O-glycosylated forms of human parathyroid hormone produced in Saccharomyces cerevisiae: Identification of a new motif for O-glycosylation. Eur. J. Biochem. 205: 311-319.
    • (1992) Eur. J. Biochem. , vol.205 , pp. 311-319
    • Olstad, O.K.1    Reppe, S.2    Gabrielsen, O.S.3    Hartmanis, M.4    Blingsmo, O.R.5    Gautvik, V.T.6
  • 13
    • 0028218361 scopus 로고
    • Expression of human parathyroid hormone production in mammalian cells, Escherichia coli and Saccharomyces cerevisiae
    • Rokkones, E., Kareem, B. N., Olstad, O. K., Hogset, A., Schenstrom, K., Hannson, L., Gautvik, K. M. 1994. Expression of human parathyroid hormone production in mammalian cells, Escherichia coli and Saccharomyces cerevisiae. J. Biotechnol. 33: 293-306.
    • (1994) J. Biotechnol. , vol.33 , pp. 293-306
    • Rokkones, E.1    Kareem, B.N.2    Olstad, O.K.3    Hogset, A.4    Schenstrom, K.5    Hannson, L.6    Gautvik, K.M.7
  • 18
    • 0028804168 scopus 로고
    • Small bone-building fragments of parathyroid hormone: New therapeutic agents for osteoporosis
    • Whitfield, J. F., Morley, P. 1995. Small bone-building fragments of parathyroid hormone: New therapeutic agents for osteoporosis. Trends Pharm. Sci. 16: 382-386.
    • (1995) Trends Pharm. Sci. , vol.16 , pp. 382-386
    • Whitfield, J.F.1    Morley, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.