Connecting LKB1 and AMPK links metabolism with cancer

Journal of Biology

Volumn 2, Issue 4, 2003, Pages

  Moore, Pete ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADENYLATE KINASE; METFORMIN; PHENFORMIN; PROTEIN KINASE; PROTEIN KINASE LKB1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CANCER; CANCER CELL; CELL ACTIVATION; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; DIABETES MELLITUS; DOWNSTREAM PROCESSING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE MUTATION; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PEUTZ JEGHERS SYNDROME; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; TREATMENT FAILURE; TUMOR SUPPRESSOR GENE;

EID: 0344420303     PISSN: 14785854     EISSN: 14754924     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Sutherland CM, Hawley SA, McCartney RR, Leech A, Stark MJ, Schmidt MC, Hardie DG: Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr Biol 2003, 13:1299-1305.
2. Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG: Complexes between the LKB1 tumour suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2003, 2:28.
3. Hong S, Leiper FC, Woods A, Carling D, Carlson M: Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci USA 2003, 100:8839-8843.