-
1
-
-
0034836506
-
Flavonoids: A review of probable mechanisms of action and potential applications
-
Nijveldt, R.; van Nood, E.; van Hoorn, D.; Boelens, P.; van Norren, K.; van Leeuwen, P. Flavonoids: a review of probable mechanisms of action and potential applications. Am. J. Clin. Nutr. 2001, 74, 418-425.
-
(2001)
Am. J. Clin. Nutr
, vol.74
, pp. 418-425
-
-
Nijveldt, R.1
van Nood, E.2
van Hoorn, D.3
Boelens, P.4
van Norren, K.5
van Leeuwen, P.6
-
2
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh, Y.-J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer. 2003, 3, 768-780.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.-J.1
-
3
-
-
2442430353
-
Polyphenols: Food sources and bioavailability
-
Manach, C; Scalbert, A.; Morand, C; Rémésy, C; Jiménez, L. Polyphenols: food sources and bioavailability. Am. J. Clin. Nutr. 2004, 79, 727-747.
-
(2004)
Am. J. Clin. Nutr
, vol.79
, pp. 727-747
-
-
Manach, C.1
Scalbert, A.2
Morand, C.3
Rémésy, C.4
Jiménez, L.5
-
4
-
-
0032844037
-
The small intestine can both absorb and glucuronidate luminal flavonoids
-
Spencer, J.; Chowrimootoo, G.; Choudhury, R.; Debnam, E.; Srai, S.; Rice-Evans, C. The small intestine can both absorb and glucuronidate luminal flavonoids. FEBS Lett. 1999, 458, 224-230.
-
(1999)
FEBS Lett
, vol.458
, pp. 224-230
-
-
Spencer, J.1
Chowrimootoo, G.2
Choudhury, R.3
Debnam, E.4
Srai, S.5
Rice-Evans, C.6
-
5
-
-
0036740112
-
Tea catechins protect against lead-induced cytotoxicity, lipid peroxidation, and membrane fluidity in HepG2 cells
-
Chen, L.; Yang, X.; Jiao, H.; Zhao, B. Tea catechins protect against lead-induced cytotoxicity, lipid peroxidation, and membrane fluidity in HepG2 cells. Toxicol. Sci. 2002, 69, 149-156.
-
(2002)
Toxicol. Sci
, vol.69
, pp. 149-156
-
-
Chen, L.1
Yang, X.2
Jiao, H.3
Zhao, B.4
-
6
-
-
3142536557
-
Prooxidant property of green tea polyphenols epicatechin and epigallocatechin-3-gallate: Implications for anticancer properties
-
Azam, S.; Hadi, N.; Khan, N. U.; Hadi, S. M. Prooxidant property of green tea polyphenols epicatechin and epigallocatechin-3-gallate: implications for anticancer properties. Toxicol. in Vitro 2004, 18, 555-561.
-
(2004)
Toxicol. in Vitro
, vol.18
, pp. 555-561
-
-
Azam, S.1
Hadi, N.2
Khan, N.U.3
Hadi, S.M.4
-
7
-
-
29744436287
-
Protective effect of ellagic and chlorogenic acids against oxidative stress in PC12 cells
-
Pavlica, S.; Gebhardt, R. Protective effect of ellagic and chlorogenic acids against oxidative stress in PC12 cells. Free Radical Res. 2005, 39, 1377-1390.
-
(2005)
Free Radical Res
, vol.39
, pp. 1377-1390
-
-
Pavlica, S.1
Gebhardt, R.2
-
8
-
-
0034730948
-
Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells
-
Tan, X.; Hu, D.; Li, S.; Han, Y.; Zhang, Y.; Zhou, D. Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. Cancer Lett. 2000, 158, 1-6.
-
(2000)
Cancer Lett
, vol.158
, pp. 1-6
-
-
Tan, X.1
Hu, D.2
Li, S.3
Han, Y.4
Zhang, Y.5
Zhou, D.6
-
9
-
-
0035951399
-
Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells
-
Chung, L. Y.; Cheung, T. C; Kong, S. K.; Fung, K. P.; Choy, Y. M.; Chan, Z. Y.; Kwok, T. T. Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells. Life Sci. 2001, 68, 1207-1214.
-
(2001)
Life Sci
, vol.68
, pp. 1207-1214
-
-
Chung, L.Y.1
Cheung, T.C.2
Kong, S.K.3
Fung, K.P.4
Choy, Y.M.5
Chan, Z.Y.6
Kwok, T.T.7
-
10
-
-
0036035557
-
Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells
-
Zheng, Q.; Hirose, Y.; Yoshimi, N.; Murakami, A.; Koshimizu, M.; Ohigashi, H.; Sakata, K.; Matsumoto, Y.; Sayama, Y.; Mori, H. Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells. J. Cancer Res. Clin. Oncol. 2002, 128, 539-546.
-
(2002)
J. Cancer Res. Clin. Oncol
, vol.128
, pp. 539-546
-
-
Zheng, Q.1
Hirose, Y.2
Yoshimi, N.3
Murakami, A.4
Koshimizu, M.5
Ohigashi, H.6
Sakata, K.7
Matsumoto, Y.8
Sayama, Y.9
Mori, H.10
-
11
-
-
0034530130
-
Induction of cytoxicity by chlorogenic acid in human oral tumor cell lines
-
Jiang, Y.; Kusama, K.; Satoh, K.; Takayama, E.; Watanabe, S.; Sakagami, H. Induction of cytoxicity by chlorogenic acid in human oral tumor cell lines. Phytomedicine 2000, 7, 483-491.
-
(2000)
Phytomedicine
, vol.7
, pp. 483-491
-
-
Jiang, Y.1
Kusama, K.2
Satoh, K.3
Takayama, E.4
Watanabe, S.5
Sakagami, H.6
-
12
-
-
33745764186
-
Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity
-
Hsu, C. L.; Huang, S. L.; Yen, G. C. Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity. J. Agric. Food Chem. 2006, 54, 4191-4197.
-
(2006)
J. Agric. Food Chem
, vol.54
, pp. 4191-4197
-
-
Hsu, C.L.1
Huang, S.L.2
Yen, G.C.3
-
13
-
-
1542605222
-
Flavonoids: Antioxidants or signalling molecules
-
Williams, R.; Spencer, J.; Rice-Evans, C. Flavonoids: antioxidants or signalling molecules. Free Radical Biol. Med. 2004, 36, 838-849.
-
(2004)
Free Radical Biol. Med
, vol.36
, pp. 838-849
-
-
Williams, R.1
Spencer, J.2
Rice-Evans, C.3
-
14
-
-
0346725840
-
Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes
-
Valdes, F.; Murillo, M. M.; Valverde, A. M.; Herrera, B.; Sanchez, A.; Benito, M.; Fernandez, M.; Fabregat, I. Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes. Exp. Cell Res. 2004, 292, 209-218.
-
(2004)
Exp. Cell Res
, vol.292
, pp. 209-218
-
-
Valdes, F.1
Murillo, M.M.2
Valverde, A.M.3
Herrera, B.4
Sanchez, A.5
Benito, M.6
Fernandez, M.7
Fabregat, I.8
-
15
-
-
17644390182
-
Response of the antioxidant defense system to tert-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2)
-
Alia, M.; Ramos, S.; Mateos, R.; Bravo, L.; Goya, L. Response of the antioxidant defense system to tert-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2). J. Biochem. Mol. Toxicol. 2005, 19, 119-128.
-
(2005)
J. Biochem. Mol. Toxicol
, vol.19
, pp. 119-128
-
-
Alia, M.1
Ramos, S.2
Mateos, R.3
Bravo, L.4
Goya, L.5
-
16
-
-
0017064979
-
A fluorometric method for determination of oxidised and reduced glutathione in tissues
-
Hissin, P.; Hilf, R. A fluorometric method for determination of oxidised and reduced glutathione in tissues. Anal. Biochem. 1976, 74, 214-226.
-
(1976)
Anal. Biochem
, vol.74
, pp. 214-226
-
-
Hissin, P.1
Hilf, R.2
-
17
-
-
0034874036
-
Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes
-
Herrera, B.; Fernandez, M.; Alvarez, A.; Roncero, C; Benito, M.; Gil, J.; Fabregat, I. Activation of caspases occurs downstream from radical oxygen species production, Bcl-xL down-regulation, and early cytochrome C release in apoptosis induced by transforming growth factor beta in rat fetal hepatocytes. Hepatology 2001, 34, 548-556.
-
(2001)
Hepatology
, vol.34
, pp. 548-556
-
-
Herrera, B.1
Fernandez, M.2
Alvarez, A.3
Roncero, C.4
Benito, M.5
Gil, J.6
Fabregat, I.7
-
18
-
-
13944281987
-
Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2)
-
Ramos, S.; Alia, M.; Bravo, L.; Goya, L. Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2). J. Agric. Food Chem. 2005, 53, 1271-1280.
-
(2005)
J. Agric. Food Chem
, vol.53
, pp. 1271-1280
-
-
Ramos, S.1
Alia, M.2
Bravo, L.3
Goya, L.4
-
19
-
-
0035146929
-
Life-or-death decisions by the Bcl-2 protein family
-
Adams, J.; Cory, S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 2001, 26, 61-66.
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 61-66
-
-
Adams, J.1
Cory, S.2
-
20
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
Nicholson, K.; Anderson, N. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal. 2002, 14, 381-395.
-
(2002)
Cell Signal
, vol.14
, pp. 381-395
-
-
Nicholson, K.1
Anderson, N.2
-
21
-
-
0034881019
-
Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
-
Ballif, B.; Blenis, J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ. 2001, 12, 397-408.
-
(2001)
Cell Growth Differ
, vol.12
, pp. 397-408
-
-
Ballif, B.1
Blenis, J.2
-
22
-
-
11844277731
-
Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity
-
Babich, H.; Krupka, M. E.; Nissim, H. A.; Zuckerbraun, H. L. Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. Toxicol. in Vitro 2005, 19, 231-242.
-
(2005)
Toxicol. in Vitro
, vol.19
, pp. 231-242
-
-
Babich, H.1
Krupka, M.E.2
Nissim, H.A.3
Zuckerbraun, H.L.4
-
23
-
-
0035313981
-
The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells
-
Mitsui, H.; Takuwa, N.; Maruyama, T.; Maekawa, H.; Hirayama, M.; Sawatari, T.; Hashimoto, N.; Takuwa, Y.; Kimura, S. The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells. Int. J. Cancer. 2001, 92, 55-62.
-
(2001)
Int. J. Cancer
, vol.92
, pp. 55-62
-
-
Mitsui, H.1
Takuwa, N.2
Maruyama, T.3
Maekawa, H.4
Hirayama, M.5
Sawatari, T.6
Hashimoto, N.7
Takuwa, Y.8
Kimura, S.9
-
24
-
-
23044442718
-
Inhibition of activator protein-1, NF-κTB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid
-
Feng, R.; Lu, Y.; Bowman, L. L.; Qian, Y.; Castranova, V.; Ding, M. Inhibition of activator protein-1, NF-κTB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. J. Biol. Chem. 2005, 280, 27888-27895.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 27888-27895
-
-
Feng, R.1
Lu, Y.2
Bowman, L.L.3
Qian, Y.4
Castranova, V.5
Ding, M.6
-
25
-
-
0033805296
-
Triggering and modulation of apoptosis by oxidative stress
-
Chandra, J.; Samali, A.; Orrenius, S. Triggering and modulation of apoptosis by oxidative stress. Free Radical Biol. Med. 2000, 29, 323-333.
-
(2000)
Free Radical Biol. Med
, vol.29
, pp. 323-333
-
-
Chandra, J.1
Samali, A.2
Orrenius, S.3
-
26
-
-
33947581338
-
Hepatoprotective constituents in plants 15: Protective effects of natural-occurring flavonoids and miscellaneous phenolic compounds as determined in an HepG2 cell cytotoxicity assay
-
Kinjo, J.; Hitoshi, M.; Tsuchihashi, R.; Korematsu, Y.; Miyakoshi, M.; Murakami, T.; Niiho, D.; Mizutani, K.; Tanaka, T.; Nonaka, G.; Nohara, T.; Okawa, M.; Okabe, H. Hepatoprotective constituents in plants 15: protective effects of natural-occurring flavonoids and miscellaneous phenolic compounds as determined in an HepG2 cell cytotoxicity assay. J. Nat. Med. 2006, 60, 36-41.
-
(2006)
J. Nat. Med
, vol.60
, pp. 36-41
-
-
Kinjo, J.1
Hitoshi, M.2
Tsuchihashi, R.3
Korematsu, Y.4
Miyakoshi, M.5
Murakami, T.6
Niiho, D.7
Mizutani, K.8
Tanaka, T.9
Nonaka, G.10
Nohara, T.11
Okawa, M.12
Okabe, H.13
-
27
-
-
0033980354
-
Comparative chemopreventive mechanisms of green tea and selected polyphenol extracts measured by in vitro bioassays
-
Steele, V.; Kelloff, G.; Balentine, D.; Boone, C; Mehta, R.; Bagheri, D.; Sigman, C; Zhu, S.; Sharma, S. Comparative chemopreventive mechanisms of green tea and selected polyphenol extracts measured by in vitro bioassays. Carcinogenesis. 2000, 21, 63-67.
-
(2000)
Carcinogenesis
, vol.21
, pp. 63-67
-
-
Steele, V.1
Kelloff, G.2
Balentine, D.3
Boone, C.4
Mehta, R.5
Bagheri, D.6
Sigman, C.7
Zhu, S.8
Sharma, S.9
-
28
-
-
0035868353
-
Epicatechin and its in vivo metabolite, 3′-O-methyl epicatechin, protect human fibroblasts from oxidative-stress induced cell death involving caspase-3 activation
-
Spencer, J.; Schroeter, H.; Kuhnle, G.; Srai, S.; Tyrrell, R.; Hahn, U.; Rice-Evans, C. Epicatechin and its in vivo metabolite, 3′-O-methyl epicatechin, protect human fibroblasts from oxidative-stress induced cell death involving caspase-3 activation. Biochem. J. 2001, 354, 493-500.
-
(2001)
Biochem. J
, vol.354
, pp. 493-500
-
-
Spencer, J.1
Schroeter, H.2
Kuhnle, G.3
Srai, S.4
Tyrrell, R.5
Hahn, U.6
Rice-Evans, C.7
-
29
-
-
33745913944
-
Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism
-
Yip, E. C. H.; Chan, A. S. L.; Pang, H.; Wong, Y. H. Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism. Cell. Biol. Toxicol. 2006, 22, 293-302.
-
(2006)
Cell. Biol. Toxicol
, vol.22
, pp. 293-302
-
-
Yip, E.C.H.1
Chan, A.S.L.2
Pang, H.3
Wong, Y.H.4
-
30
-
-
33645458952
-
Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: Modulatory effect of cellular G6PD status
-
Ho, H.; Wei, T.; Cheng, M.; Chiu, D. Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status. J. Agric. Food Chem. 2006, 54, 1638-1645.
-
(2006)
J. Agric. Food Chem
, vol.54
, pp. 1638-1645
-
-
Ho, H.1
Wei, T.2
Cheng, M.3
Chiu, D.4
-
31
-
-
17144366551
-
Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrates inositol-1,4,5-triphosphate 3-kinases and inositol polyphosphate multikinase
-
Mayr, G. W.; Windhorst, S.; Hillemeier, K. Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrates inositol-1,4,5-triphosphate 3-kinases and inositol polyphosphate multikinase. J. Biol. Chem. 2005, 280, 13229-13240.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 13229-13240
-
-
Mayr, G.W.1
Windhorst, S.2
Hillemeier, K.3
-
32
-
-
24944499726
-
Monomeric and oligomeric flavanols are agonists of membrane androgen receptors
-
Nifli, A.; Bosson-Kouame, A.; Papadopoulou, N.; Kogia, C; Kampa, M.; Castagnino, C; Stournaras, C; Vercauteren, J.; Castanas, E. Monomeric and oligomeric flavanols are agonists of membrane androgen receptors. Exp. Cell Res. 2005, 309, 329-339.
-
(2005)
Exp. Cell Res
, vol.309
, pp. 329-339
-
-
Nifli, A.1
Bosson-Kouame, A.2
Papadopoulou, N.3
Kogia, C.4
Kampa, M.5
Castagnino, C.6
Stournaras, C.7
Vercauteren, J.8
Castanas, E.9
-
33
-
-
0037937302
-
Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes
-
Hsu, S.; Bollag, W.; Huang, L.; Singh, B.; Sharawy, M.; Yamamoto, T.; Schuster, G. Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J. Pharmacol. Exp. Ther. 2003, 306, 29-34.
-
(2003)
J. Pharmacol. Exp. Ther
, vol.306
, pp. 29-34
-
-
Hsu, S.1
Bollag, W.2
Huang, L.3
Singh, B.4
Sharawy, M.5
Yamamoto, T.6
Schuster, G.7
-
34
-
-
33746671438
-
-
Li, H.-L.; Huang, Y.; Zhang, C.-N.; Liu, G.; Wei, Y.-S.; Wang, A. B.; Liu, Y.-Q.; Hui, R.-T.; Wei, C; Williams, G. M.; Liu, D.-P.; Liang, C.-C. Epigallocatechin-3-gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radical Biol. Med. 2006, 40, 1756-1775.
-
Li, H.-L.; Huang, Y.; Zhang, C.-N.; Liu, G.; Wei, Y.-S.; Wang, A. B.; Liu, Y.-Q.; Hui, R.-T.; Wei, C; Williams, G. M.; Liu, D.-P.; Liang, C.-C. Epigallocatechin-3-gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radical Biol. Med. 2006, 40, 1756-1775.
-
-
-
-
35
-
-
0034655603
-
Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κB in cancer cells versus normal cells
-
Ahmad, N.; Gupta, S.; Mukhtar, H. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor κB in cancer cells versus normal cells. Arch. Biochem. Biophys. 2000, 376, 338-346.
-
(2000)
Arch. Biochem. Biophys
, vol.376
, pp. 338-346
-
-
Ahmad, N.1
Gupta, S.2
Mukhtar, H.3
|