Folate deficiency and homocysteine induce toxicity in cultured dorsal root ganglion neurons via cytosolic calcium accumulation

Aging Cell

Volumn 3, Issue 2, 2004, Pages 71-76

  Tjiattas, Lindsay ^a   Ortiz, Daniela O ^a   Dhivant, Sirikarnt ^a   Mitton, Kerrie ^a   Rogers, Eugene ^a   Shea, Thomas B ^a  

^a University of Massachusetts Lowell   (United States)

Author keywords

Amyotropic lateral sclerosis; Calcium; Dorsal root ganglion neurons; Folate; Homocysteine; Motor neuron disease

Indexed keywords

3 DEAZAADENOSINE; CALCIUM; CALCIUM ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; DIZOCILPINE; FOLIC ACID; HOMOCYSTEINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NIMODIPINE; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN; VOLTAGE GATED CALCIUM CHANNEL; 3 DEAZAADENINE; 3-DEAZAADENINE; ADENINE; ANILINE DERIVATIVE; DIZOCILPINE MALEATE; DRUG DERIVATIVE; FLUO 3; XANTHENE DERIVATIVE;

AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; EMBRYO; FOLIC ACID DEFICIENCY; MITOCHONDRION; NERVE CELL; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SPINAL GANGLION; TIME; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHICK EMBRYO; CYTOLOGY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY;

ADENINE; ANILINE COMPOUNDS; ANIMALS; CALCIUM; CELLS, CULTURED; CHICK EMBRYO; CYTOSOL; DIZOCILPINE MALEATE; FOLIC ACID; FOLIC ACID DEFICIENCY; GANGLIA, SPINAL; HOMOCYSTEINE; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NEURONS; NIMODIPINE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; THAPSIGARGIN; XANTHENES;

EID: 7444239650     PISSN: 14749718     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1474-9728.2004.00086.x     Document Type: Article

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