Folate depletion induced by methotrexate affects methionine synthase activity and its susceptibility to inactivation by nitrous oxide

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 3, 1997, Pages 1305-1311

  Fiskerstrand, Torunn ^a   Ueland, Per Magne ^a   Refsum, Helga ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; FOLIC ACID; HOMOCYSTEINE; MECOBALAMIN; METHIONINE SYNTHASE; METHOTREXATE; NITROUS OXIDE;

ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INACTIVATION; GLIOMA CELL; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; ADULT; ANESTHETICS, INHALATION; FEMALE; FOLIC ACID; FOLIC ACID ANTAGONISTS; HOMOCYSTEINE; HUMANS; METHOTREXATE; METHYLATION; NITROUS OXIDE; TUMOR CELLS, CULTURED; VITAMIN B 12;

EID: 0030967427     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

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