SCOPUS 정보 검색 플랫폼 - 논문 보기

메뉴 건너뛰기

Volumn 63, Issue 11, 2009, Pages 737-744

Engineering kinases to phosphorylate nucleoside analogs for antiviral and cancer therapy

(3) Lutz, Stefan a Liu, Lingfeng b Liu, Yichen b

a EMORY UNIVERSITY (United States)

b NONE

Author keywords

Deoxynucleoside kinase; Directed evolution; Enzyme catalysis; Nucleoside analogs; Protein engineering

Indexed keywords

EID: 72749126099 PISSN: 00094293 EISSN: None Source Type: Journal
DOI: 10.2533/chimia.2009.737 Document Type: Article

Times cited : (7)

References (61)

1
- 0001289724
- E. Fischer, Ber. Dtsch. Chem. Ges. 1894, 27, 2984.
- (1894) Ber. Dtsch. Chem. Ges. , vol.27 , pp. 2984
- Fischer, E.¹

2
- 0029162556
- E. S. Arner, S. Eriksson, Pharmacol. Ther. 1995, 67, 155.
- (1995) Pharmacol. Ther. , vol.67 , pp. 155
- Arner, E.S.¹ Eriksson, S.²

3
- 0036693511
- S. Eriksson, B. Munch-Petersen, K. Johansson, H. Eklund, Cell. Mol. Life Sci. 2002, 59, 1327.
- (2002) Cell. Mol. Life Sci. , vol.59 , pp. 1327
- Eriksson, S.¹ Munch-Petersen, B.² Johansson, K.³ Eklund, H.⁴

4
- 0026464790
- G. A. Gentry, Pharmacol. Ther. 1992, 54, 319.
- (1992) Pharmacol. Ther. , vol.54 , pp. 319
- Gentry, G.A.¹

5
- 0033545678
- J. Shi, J. J. McAtee, S. Schlueter Wirtz, P. Tharnish, A. Juodawlkis, D. C. Liotta, R. F. Schinazi, J. Med. Chem. 1999, 42, 859.
- (1999) J. Med. Chem. , vol.42 , pp. 859
- Shi, J.¹ McAtee, J.J.² Schlueter Wirtz, S.³ Tharnish, P.⁴ Juodawlkis, A.⁵ Liotta, D.C.⁶ Schinazi, R.F.⁷

6
- 0022485359
- F. L. Moolten, Cancer Res. 1986, 46, 5276.
- (1986) Cancer Res. , vol.46 , pp. 5276
- Moolten, F.L.¹

7
- 0026772206
- K. W. Culver, Z. Ram, S. Wallbridge, H. Ishii, E. H. Oldfield, R. M. Blaese, Science 1992, 256, 1550.
- (1992) Science , vol.256 , pp. 1550
- Culver, K.W.¹ Ram, Z.² Wallbridge, S.³ Ishii, H.⁴ Oldfield, E.H.⁵ Blaese, R.M.⁶

8
- 33745712217
- L. P. Jordheim, C. M. Galmarini, C. Dumontet, Cancer Chemother. Pharmacol. 2006, 58, 547.
- (2006) Cancer Chemother. Pharmacol. , vol.58 , pp. 547
- Jordheim, L.P.¹ Galmarini, C.M.² Dumontet, C.³

9
- 33845627382
- N. Solaroli, M. Johansson, J. Balzarini, A. Karlsson, Gene Ther. 2007, 14, 86.
- (2007) Gene Ther. , vol.14 , pp. 86
- Solaroli, N.¹ Johansson, M.² Balzarini, J.³ Karlsson, A.⁴

10
- 17044364766
- S. Song, Z. F. Pursell, W. C. Copeland, M. J. Longley, T. A. Kunkel, C. K. Mathews, Proc. Natl. Acad. Sci. USA 2005, 102, 4990.
- (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4990
- Song, S.¹ Pursell, Z.F.² Copeland, W.C.³ Longley, M.J.⁴ Kunkel, T.A.⁵ Mathews, C.K.⁶

11
- 65249177164
- C. A. Tracewell, F. H. Arnold, Curr. Opin. Chem. Biol. 2009, 13, 3.
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 3
- Tracewell, C.A.¹ Arnold, F.H.²

12
- 65249143885
- J. A. Gerlt, P. C. Babbitt, Curr. Opin. Chem. Biol. 2009, 13, 10.
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 10
- Gerlt, J.A.¹ Babbitt, P.C.²

13
- 65349124747
- P. Bernhardt, S. E. O'Connor, Curr. Opin. Chem. Biol. 2009, 13, 35.
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 35
- Bernhardt, P.¹ O'Connor, S.E.²

14
- 65249128025
- J. Tao, J. H. Xu, Curr. Opin. Chem. Biol. 2009, 13, 43.
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 43
- Tao, J.¹ Xu, J.H.²

15
- 68049106179
- N.J. Turner, Nat. Chem. Biol. 2009, 5, 567.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 567
- Turner, N.J.¹

16
- 68049111471
- R.J. Kazlauskas, U.T. Bornscheuer, Nat. Chem. Biol. 2009, 5, 526.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 526
- Kazlauskas, R.J.¹ Bornscheuer, U.T.²

17
- 3543106035
- S. Lutz, W. M. Patrick, Curr. Opin. Biotechnol. 2004, 15, 291.
- (2004) Curr. Opin. Biotechnol. , vol.15 , pp. 291
- Lutz, S.¹ Patrick, W.M.²

18
- 33744496842
- E. T. Farinas, Comb. Chem. High Throughput. Screen. 2006, 9, 321.
- (2006) Comb. Chem. High Throughput. Screen. , vol.9 , pp. 321
- Farinas, E.T.¹

19
- 33747130345
- A. D. Griffiths, D. S. Tawfik, Trends Biotechnol. 2006, 24, 395.
- (2006) Trends Biotechnol. , vol.24 , pp. 395
- Griffiths, A.D.¹ Tawfik, D.S.²

20
- 34548461275
- S. Lutz, J. Lichter, L. Liu, J. Am. Chem. Soc. 2007, 129, 8714.
- (2007) J. Am. Chem. Soc. , vol.129 , pp. 8714
- Lutz, S.¹ Lichter, J.² Liu, L.³

21
- 36749053510
- D. Segura-Pena, J. Lichter, M. Trani, M. Konrad, A. Lavie, S. Lutz, Structure 2007, 15, 1555.
- (2007) Structure , vol.15 , pp. 1555
- Segura-Pena, D.¹ Lichter, J.² Trani, M.³ Konrad, M.⁴ Lavie, A.⁵ Lutz, S.⁶

22
- 34247365953
- D. Segura-Pena, S. Lutz, C. Monnerjahn, M. Konrad, A. Lavie, J. Mol. Biol. 2007, 369, 129.
- (2007) J. Mol. Biol. , vol.369 , pp. 129
- Segura-Pena, D.¹ Lutz, S.² Monnerjahn, C.³ Konrad, M.⁴ Lavie, A.⁵

23
- 11144222319
- M. Welin, U. Kosinska, N. E. Mikkelsen, C. Carnrot, C. Zhu, L. Wang, S. Eriksson, B. Munch-Petersen, H. Eklund, Proc. Natl. Acad. Sci. USA 2004, 101, 17970.
- (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17970
- Welin, M.¹ Kosinska, U.² Mikkelsen, N.E.³ Carnrot, C.⁴ Zhu, C.⁵ Wang, L.⁶ Eriksson, S.⁷ Munch-Petersen, B.⁸ Eklund, H.⁹

24
- 4344567355
- A. S. Al-Madhoun, J. Johnsamuel, R. F. Barth, W. Tjarks, S. Eriksson, Cancer Res. 2004, 64, 6280.
- (2004) Cancer Res. , vol.64 , pp. 6280
- Al-Madhoun, A.S.¹ Johnsamuel, J.² Barth, R.F.³ Tjarks, W.⁴ Eriksson, S.⁵

25
- 0034092788
- B. Munch-Petersen, W. Knecht, C. Lenz, L. Sondergaard, J. Piskur, J. Biol. Chem. 2000, 275, 6673.
- (2000) J. Biol. Chem. , vol.275 , pp. 6673
- Munch-Petersen, B.¹ Knecht, W.² Lenz, C.³ Sondergaard, L.⁴ Piskur, J.⁵

26
- 0037007213
- W. Knecht, M. P. Sandrini, K. Johansson, H. Eklund, B. Munch-Petersen, J. Piskur, EMBO J. 2002, 21, 1873.
- (2002) EMBO J. , vol.21 , pp. 1873
- Knecht, W.¹ Sandrini, M.P.² Johansson, K.³ Eklund, H.⁴ Munch-Petersen, B.⁵ Piskur, J.⁶

27
- 0038419639
- E. Sabini, S. Ort, C. Monnerjahn, M. Konrad, A. Lavie, Nat. Struct. Biol. 2003, 10, 513.
- (2003) Nat. Struct. Biol. , vol.10 , pp. 513
- Sabini, E.¹ Ort, S.² Monnerjahn, C.³ Konrad, M.⁴ Lavie, A.⁵

28
- 42349087011
- P. Iyidogan, S. Lutz, Biochemistry 2008, 47, 4711.
- (2008) Biochemistry , vol.47 , pp. 4711
- Iyidogan, P.¹ Lutz, S.²

29
- 0014152202
- K. Igarashi, S. Hiraga, T. Yura, Genetics 1967, 57, 643.
- (1967) Genetics , vol.57 , pp. 643
- Igarashi, K.¹ Hiraga, S.² Yura, T.³

30
- 11244281311
- A. Aharoni, L. Gaidukov, O. Khersonsky, Q. G. S. Mc, C. Roodveldt, D. S. Tawfik, Nat. Genet. 2005, 37, 73.
- (2005) Nat. Genet. , vol.37 , pp. 73
- Aharoni, A.¹ Gaidukov, L.² Khersonsky, O.³ Mc, Q.G.S.⁴ Roodveldt, C.⁵ Tawfik, D.S.⁶

31
- 33846648000
- M. L. Gerth, S. Lutz, Biochem. Biophys. Res. Commun. 2007, 354, 802.
- (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 802
- Gerth, M.L.¹ Lutz, S.²

32
- 72749091673
- Ed. S. Lutz, U. T. Bornscheuer, Wiley VCH Verlag, Weinheim
- M. Trani, S. Lutz, in 'Protein Engineering Handbook', Ed. S. Lutz, U. T. Bornscheuer, Wiley VCH Verlag, Weinheim, 2008, p. 493.
- (2008) Protein Engineering Handbook , pp. 493
- Trani, M.¹ Lutz, S.²

33
- 34249939115
- M. L. Gerth, S. Lutz, J. Mol. Biol. 2007, 370, 742.
- (2007) J. Mol. Biol. , vol.370 , pp. 742
- Gerth, M.L.¹ Lutz, S.²

34
- 0035949702
- S. Lutz, M. Ostermeier, G. L. Moore, C. D. Maranas, S. J. Benkovic, Proc. Natl. Acad. Sci. USA. 2001, 98, 11248.
- (2001) Proc. Natl. Acad. Sci. USA. , vol.98 , pp. 11248
- Lutz, S.¹ Ostermeier, M.² Moore, G.L.³ Maranas, C.D.⁴ Benkovic, S.J.⁵

35
- 0033037012
- F. C. Christians, L. Scapozza, A. Crameri, G. Folkers, W. P. Stemmer, Nat. Biotechnol. 1999, 17, 259.
- (1999) Nat. Biotechnol. , vol.17 , pp. 259
- Christians, F.C.¹ Scapozza, L.² Crameri, A.³ Folkers, G.⁴ Stemmer, W.P.⁵

36
- 33751074907
- L. L. Lairson, A. G. Watts, W. W. Wakarchuk, S. G. Withers, Nat. Chem. Biol. 2006, 2, 724.
- (2006) Nat. Chem. Biol. , vol.2 , pp. 724
- Lairson, L.L.¹ Watts, A.G.² Wakarchuk, W.W.³ Withers, S.G.⁴

37
- 0033772183
- M. J. Olsen, D. Stephens, D. Griffiths, P. Daugherty, G. Georgiou, B. L. Iverson, Nat. Biotechnol. 2000, 18, 1071.
- (2000) Nat. Biotechnol. , vol.18 , pp. 1071
- Olsen, M.J.¹ Stephens, D.² Griffiths, D.³ Daugherty, P.⁴ Georgiou, G.⁵ Iverson, B.L.⁶

38
- 0015530393
- J. R. Barrio, J. A. Secrist, 3rd, N. J. Leonard, Biochem. Biophys. Res. Commun. 1972, 46, 597.
- (1972) Biochem. Biophys. Res. Commun. , vol.46 , pp. 597
- Barrio, J.R.¹ Secrist III, J.A.² Leonard, N.J.³

39
- 1242338125
- D. A. Berry, K. Y. Jung, D. S. Wise, A. D. Sercel, W. H. Pearson, H. Mackie, J. B. Randolph, R. L. Somers, Tetrahedron Lett. 2004, 45, 2457.
- (2004) Tetrahedron Lett. , vol.45 , pp. 2457
- Berry, D.A.¹ Jung, K.Y.² Wise, D.S.³ Sercel, A.D.⁴ Pearson, W.H.⁵ Mackie, H.⁶ Randolph, J.B.⁷ Somers, R.L.⁸

40
- 0031023096
- M. E. Hawkins, W. Pfleiderer, F. M. Balis, D. Porter, J. R. Knutson, Anal. Biochem. 1997, 244, 86.
- (1997) Anal. Biochem. , vol.244 , pp. 86
- Hawkins, M.E.¹ Pfleiderer, W.² Balis, F.M.³ Porter, D.⁴ Knutson, J.R.⁵

41
- 0033774619
- G. Georgiou, Adv. Protein. Chem. 2000, 55, 293.
- (2000) Adv. Protein. Chem. , vol.55 , pp. 293
- Georgiou, G.¹

42
- 67949109571
- L. Liu, Y. Li, D. Liotta, S. Lutz, Nucleic Acids Res. 2009, 37, 4472.
- (2009) Nucleic Acids Res. , vol.37 , pp. 4472
- Liu, L.¹ Li, Y.² Liotta, D.³ Lutz, S.⁴

43
- 0038629174
- N. E. Mikkelsen, K. Johansson, A. Karlsson, W. Knecht, G. Andersen, J. Piskur, B. Munch-Petersen, H. Eklund, Biochemistry 2003, 42, 5706.
- (2003) Biochemistry , vol.42 , pp. 5706
- Mikkelsen, N.E.¹ Johansson, K.² Karlsson, A.³ Knecht, W.⁴ Andersen, G.⁵ Piskur, J.⁶ Munch-Petersen, B.⁷ Eklund, H.⁸

44
- 33747598700
- C. L. Willmon, E. Krabbenhoft, M. E. Black, Gene Ther. 2006, 13, 1309.
- (2006) Gene Ther. , vol.13 , pp. 1309
- Willmon, C.L.¹ Krabbenhoft, E.² Black, M.E.³

45
- 0033544959
- R. Brundiers, A. Lavie, T. Veit, J. Reinstein, I. Schlichting, N. Ostermann, R. S. Goody, M. Konrad, J. Biol. Chem. 1999, 274, 35289.
- (1999) J. Biol. Chem. , vol.274 , pp. 35289
- Brundiers, R.¹ Lavie, A.² Veit, T.³ Reinstein, J.⁴ Schlichting, I.⁵ Ostermann, N.⁶ Goody, R.S.⁷ Konrad, M.⁸

46
- 0032564339
- A. Lavie, N. Ostermann, R. Brundiers, R.S. Goody, J. Reinstein, M. Konrad, I. Schichtling, Proc. Natl. Acad. Sci. USA 1998, 95, 14045.
- (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14045
- Lavie, A.¹ Ostermann, N.² Brundiers, R.³ Goody, R.S.⁴ Reinstein, J.⁵ Konrad, M.⁶ Schichtling, I.⁷

47
- 0141594761
- A. Gardberg, L. Shuvalova, C. Monnerjahn, M. Konrad, A. Lavie, Structure 2003, 11, 1265.
- (2003) Structure , vol.11 , pp. 1265
- Gardberg, A.¹ Shuvalova, L.² Monnerjahn, C.³ Konrad, M.⁴ Lavie, A.⁵

48
- 0033795931
- I. Lascu, P. Gonin, J. Bioenerg. Biomembr. 2000, 32, 237.
- (2000) J. Bioenerg. Biomembr. , vol.32 , pp. 237
- Lascu, I.¹ Gonin, P.²

49
- 0018603658
- M. S. Chen, J. Walker, W. H. Prusoff, J. Biol. Chem. 1979, 254, 10747.
- (1979) J. Biol. Chem. , vol.254 , pp. 10747
- Chen, M.S.¹ Walker, J.² Prusoff, W.H.³

50
- 0018264671
- M. S. Chen, W. H. Prusoff, J. Biol. Chem. 1978, 253, 1325.
- (1978) J. Biol. Chem. , vol.253 , pp. 1325
- Chen, M.S.¹ Prusoff, W.H.²

51
- 0026323945
- D. K. Dube, J. D. Parker, D. C. French, D. S. Cahill, S. Dube, M. S. Horwitz, K. M. Munir, L. A. Loeb, Biochemistry 1991, 30, 11760.
- (1991) Biochemistry , vol.30 , pp. 11760
- Dube, D.K.¹ Parker, J.D.² French, D.C.³ Cahill, D.S.⁴ Dube, S.⁵ Horwitz, M.S.⁶ Munir, K.M.⁷ Loeb, L.A.⁸

52
- 0028079324
- K. M. Munir, D. C. French, D. K. Dube, L. A. Loeb, Protein Eng. 1994, 7, 83.
- (1994) Protein Eng. , vol.7 , pp. 83
- Munir, K.M.¹ French, D.C.² Dube, D.K.³ Loeb, L.A.⁴

53
- 0026646614
- K. M. Munir, D. C. French, D. K. Dube, L. A. Loeb, J. Biol. Chem. 1992, 267, 6584.
- (1992) J. Biol. Chem. , vol.267 , pp. 6584
- Munir, K.M.¹ French, D.C.² Dube, D.K.³ Loeb, L.A.⁴

54
- 0027192014
- K. M. Munir, D. C. French, L. A. Loeb, Proc. Natl. Acad. Sci. USA 1993, 90, 4012.
- (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4012
- Munir, K.M.¹ French, D.C.² Loeb, L.A.³

55
- 0026655908
- M. E. Black, D. E. Hruby, J. Biol. Chem. 1992, 267, 9743.
- (1992) J. Biol. Chem. , vol.267 , pp. 9743
- Black, M.E.¹ Hruby, D.E.²

56
- 0029680175
- M. E. Black, L. A. Loeb, Methods Mol. Biol. 1996, 57, 335.
- (1996) Methods Mol. Biol. , vol.57 , pp. 335
- Black, M.E.¹ Loeb, L.A.²

57
- 0027501570
- M. E. Black, L. A. Loeb, Biochemistry 1993, 32, 11618.
- (1993) Biochemistry , vol.32 , pp. 11618
- Black, M.E.¹ Loeb, L.A.²

58
- 0036708008
- M. S. Kokoris, M. E. Black, Protein Sci. 2002, 11, 2267.
- (2002) Protein Sci. , vol.11 , pp. 2267
- Kokoris, M.S.¹ Black, M.E.²

59
- 0035139165
- B. Degreve, R. Esnouf, E. De Clercq, J. Balzarini, Mol. Pharmacol. 2001, 59, 285.
- (2001) Mol. Pharmacol. , vol.59 , pp. 285
- Degreve, B.¹ Esnouf, R.² De Clercq, E.³ Balzarini, J.⁴

60
- 0034636067
- T. A. Hinds, C. Compadre, B. K. Hurlburt, R. R. Drake, Biochemistry 2000, 39, 4105.
- (2000) Biochemistry , vol.39 , pp. 4105
- Hinds, T.A.¹ Compadre, C.² Hurlburt, B.K.³ Drake, R.R.⁴

61
- 0036878164
- K. E. Mercer, C. E. Ahn, A. Coke, C. M. Compadre, R. R. Drake, Protein Eng. 2002, 15, 903.
- (2002) Protein Eng. , vol.15 , pp. 903
- Mercer, K.E.¹ Ahn, C.E.² Coke, A.³ Compadre, C.M.⁴ Drake, R.R.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.