Modifying human thymidylate kinase to potentiate azidothymidine activation

Journal of Biological Chemistry

Volumn 274, Issue 50, 1999, Pages 35289-35292

  Brundiers, Ralf ^a   Lavie, Arnon ^b   Veit, Thomas ^b   Reinstein, Jochen ^b   Schlichting, Ilme ^b   Ostermann, Nils ^b   Goody, Roger S ^b   Konrad, Manfred ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOTRANSFERASE; THYMIDYLATE SYNTHASE; ZIDOVUDINE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEREOSPECIFICITY; VIRUS REPLICATION; YEAST;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEOSIDE-PHOSPHATE KINASE; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; THYMINE NUCLEOTIDES; ZIDOVUDINE;

EID: 0033544959     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.50.35289     Document Type: Article

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