-
1
-
-
23544453793
-
Synthesis and in vitro anti-HIV-1 activity of D-D4FC analogues
-
11th International Conference on Antiviral Research, San Diego, CA, Apr 5-10, 1998
-
Preliminary report: Shi, J.; Liotta, D. C.; Schinazi, R. F. Synthesis and in vitro anti-HIV-1 activity of D-D4FC analogues. 11th International Conference on Antiviral Research, San Diego, CA, Apr 5-10, 1998; Antiviral Res. 1998, 37, A39.
-
(1998)
Antiviral Res.
, vol.37
-
-
Shi, J.1
Liotta, D.C.2
Schinazi, R.F.3
-
2
-
-
0024564518
-
1-(2,3-Dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent
-
Mansuri, M. M.; Starrett, J. E., Jr.; Ghazzouli, I.; Hitchcock, M. J. M.; Sterzycki, R. Z.; Brankovan, V.; Lin, T. S.; August, E. M.; Prusoff, W. H.; Sommadossi, J.-P.; Martin, J. C. 1-(2,3-Dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent. J. Med. Chem. 1989, 32, 461-466.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 461-466
-
-
Mansuri, M.M.1
Starrett J.E., Jr.2
Ghazzouli, I.3
Hitchcock, M.J.M.4
Sterzycki, R.Z.5
Brankovan, V.6
Lin, T.S.7
August, E.M.8
Prusoff, W.H.9
Sommadossi, J.-P.10
Martin, J.C.11
-
3
-
-
0026666974
-
Insights into HIV chemotherapy
-
Schinazi, R. F.; Mead, J. R.; Feorino, P. M. Insights into HIV chemotherapy. AIDS Res. Hum. Retroviruses 1992, 8, 963-990.
-
(1992)
AIDS Res. Hum. Retroviruses
, vol.8
, pp. 963-990
-
-
Schinazi, R.F.1
Mead, J.R.2
Feorino, P.M.3
-
4
-
-
0023196616
-
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus
-
Lin, T.-S.; Schinazi, R. F.; Prusoff, W. H. Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus. Biochem. Pharmacol. 1987, 36, 2713-2718.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2713-2718
-
-
Lin, T.-S.1
Schinazi, R.F.2
Prusoff, W.H.3
-
5
-
-
0345522332
-
Nucleosides with dual anti-HIV and HBV activity
-
Chicago, IL, Feb 1-5, Abstract 629
-
Schinazi, R. F.; Ma, L.; Shi, J.; Hurwitz, S.; Schlueter Wirtz, S.; Kupfer, S.; Juodawlkis, A.; McAtee, J.; Liotta, D.; McClure, H.; Faraj, A.; Sommadossi, J.-P. Nucleosides with dual anti-HIV and HBV activity. 5th Conference on Retrovirus and Opportunistic Infections, Chicago, IL, Feb 1-5, 1998; Abstract 629.
-
(1998)
5th Conference on Retrovirus and Opportunistic Infections
-
-
Schinazi, R.F.1
Ma, L.2
Shi, J.3
Hurwitz, S.4
Schlueter Wirtz, S.5
Kupfer, S.6
Juodawlkis, A.7
McAtee, J.8
Liotta, D.9
McClure, H.10
Faraj, A.11
Sommadossi, J.-P.12
-
6
-
-
0033029686
-
Pharmacokinetics of the antiviral agent β-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys
-
Ma, L.; Hurwitz, S. J.; Shi, J.; McAtee, J. J.; Liotta, D. C.; McClure, H. M.; Schinazi, R. F. Pharmacokinetics of the antiviral agent β-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob. Agents Chemother. 1999, 43, 381-384.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 381-384
-
-
Ma, L.1
Hurwitz, S.J.2
Shi, J.3
McAtee, J.J.4
Liotta, D.C.5
McClure, H.M.6
Schinazi, R.F.7
-
7
-
-
0029881506
-
Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-β-L-cytidine (β-L-d4C) and 2',3'-dideoxy-2',3'-didehydro-β-L-5-fluorocytidine (β-L-fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro
-
Lin, T.-S.; Luo, M.-Z.; Liu, M.-C.; Zhu, Y.-L.; Gullen, E.; Dutschman, G. E.; Cheng, Y.-C. Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-β-L-cytidine (β-L-d4C) and 2',3'-dideoxy-2',3'-didehydro-β-L-5-fluorocytidine (β-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro. J. Med. Chem. 1996, 39, 1757-1759.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1757-1759
-
-
Lin, T.-S.1
Luo, M.-Z.2
Liu, M.-C.3
Zhu, Y.-L.4
Gullen, E.5
Dutschman, G.E.6
Cheng, Y.-C.7
-
8
-
-
0344659999
-
Anti-HIV activity, biochemistry, and pharmacokinetics of β-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine (D4FC)
-
Geneva, Switzerland, June 28-July 3, Abstract 557/41174
-
Schinazi, R. F.; Ma, L.; Shi, J.; Liotta, D. C.; Faraj, A.; Sommadossi, J.-P. Anti-HIV activity, biochemistry, and pharmacokinetics of β-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine (D4FC). 12th World AIDS Conference, Geneva, Switzerland, June 28-July 3, 1998; Abstract 557/41174.
-
(1998)
12th World AIDS Conference
-
-
Schinazi, R.F.1
Ma, L.2
Shi, J.3
Liotta, D.C.4
Faraj, A.5
Sommadossi, J.-P.6
-
9
-
-
0026720613
-
A highly stereoselective synthesis of anti-HIV 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxynucleosides
-
Beach, J. W.; Kim, H. O.; Jeong, L. S.; Nampalli, S.; Islam, Q.; Ahn, S. K.; Babu, J. R.; Chu, C. K. A highly stereoselective synthesis of anti-HIV 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxynucleosides. J. Org. Chem. 1992, 57, 3887-3894.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 3887-3894
-
-
Beach, J.W.1
Kim, H.O.2
Jeong, L.S.3
Nampalli, S.4
Islam, Q.5
Ahn, S.K.6
Babu, J.R.7
Chu, C.K.8
-
10
-
-
0031895585
-
Synthesis and biological properties of the four optical isomers of 5-o-carboranyl-2',3'-didehydro-2',3'-dideoxyuridine
-
Graciet, J.-C. G.; Shi, J.; Schinazi, R. F. Synthesis and biological properties of the four optical isomers of 5-o-carboranyl-2',3'-didehydro-2',3'-dideoxyuridine. Nucleosides Nucleotides 1998, 17, 711-727.
-
(1998)
Nucleosides Nucleotides
, vol.17
, pp. 711-727
-
-
Graciet, J.-C.G.1
Shi, J.2
Schinazi, R.F.3
-
11
-
-
0013869085
-
Nucleosides. IX. The formation of 2',3'-unsaturated pyrimidine nucleosides via a novel β-elimination reaction
-
Horwitz, J. P.; Chua, J.; Da Rooge, M. A.; Noel, M.; Klundt, I. L. Nucleosides. IX. The formation of 2',3'-unsaturated pyrimidine nucleosides via a novel β-elimination reaction. J. Org. Chem. 1966, 31, 205-211.
-
(1966)
J. Org. Chem.
, vol.31
, pp. 205-211
-
-
Horwitz, J.P.1
Chua, J.2
Da Rooge, M.A.3
Noel, M.4
Klundt, I.L.5
-
12
-
-
8944229590
-
4-(1,2,4-Triazol-1-yl)- and 4-(3-nitro-1,2,4-triazol-1-yl)-1-(β-D-2,3,5-tri-O-acetylarabinofuranosyl)- pyrimidin-2(1H)-ones. Valuable intermediates in the synthesis of derivatives of 1-(β-D-arabinofuranosyl)cytosine (Ara-C)
-
Divakar, K. J.; Reese, C. B. 4-(1,2,4-Triazol-1-yl)- and 4-(3-nitro-1,2,4-triazol-1-yl)-1-(β-D-2,3,5-tri-O-acetylarabinofuranosyl)- pyrimidin-2(1H)-ones. Valuable intermediates in the synthesis of derivatives of 1-(β-D-arabinofuranosyl)cytosine (Ara-C). J. Chem. Soc., Perkin Trans. 1 1982, 1171-1176.
-
(1982)
J. Chem. Soc., Perkin Trans. 1
, pp. 1171-1176
-
-
Divakar, K.J.1
Reese, C.B.2
-
13
-
-
0023123862
-
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro
-
Lin, T.-S.; Schinazi, R. F.; Chen, M. S.; Kinney-Thomas, E.; Prusoff, W. H. Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro. Biochem. Pharmacol. 1987, 36, 311-316.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 311-316
-
-
Lin, T.-S.1
Schinazi, R.F.2
Chen, M.S.3
Kinney-Thomas, E.4
Prusoff, W.H.5
-
14
-
-
0000315733
-
Practical catalyst for cyclic metathesis. Synthesis of functional and/or enantiopure cycloalkenes
-
Nugent, W. A.; Feldman, J.; Calabrese, J. C. Practical catalyst for cyclic metathesis. Synthesis of functional and/or enantiopure cycloalkenes. J. Am. Chem. Soc. 1995, 117, 8992-8998.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 8992-8998
-
-
Nugent, W.A.1
Feldman, J.2
Calabrese, J.C.3
-
15
-
-
0039094109
-
Highly efficient and enantioselective synthesis of carbocyclic nucleoside analogues using selective early transition metal catalysis
-
Martinez, L. E.; Nugent, W. A.; Jacobsen, E. N. Highly efficient and enantioselective synthesis of carbocyclic nucleoside analogues using selective early transition metal catalysis. J. Org. Chem. 1996, 61, 7963-7966.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 7963-7966
-
-
Martinez, L.E.1
Nugent, W.A.2
Jacobsen, E.N.3
-
16
-
-
37049089998
-
Concise racemic and highly enantioselective approaches to key intermediates for the syntheses of carbocyclic nucleosides and pseudo-ribofuranoses: Formal syntheses of carbovir
-
Hodgson, D. M.; Witherington, J.; Moloney, B. A. Concise racemic and highly enantioselective approaches to key intermediates for the syntheses of carbocyclic nucleosides and pseudo-ribofuranoses: formal syntheses of carbovir. J. Chem. Soc., Perkin Trans. 1 1994, 3373-3378.
-
(1994)
J. Chem. Soc., Perkin Trans. 1
, pp. 3373-3378
-
-
Hodgson, D.M.1
Witherington, J.2
Moloney, B.A.3
-
17
-
-
0041644739
-
A simple method for selective acylation of cytidines and cytosines under mild reaction conditions
-
Steinfeld, A. S.; Naider, F.; Becker, J. M. A simple method for selective acylation of cytidines and cytosines under mild reaction conditions. J. Chem. Res. (M) 1979, 1437-1450.
-
(1979)
J. Chem. Res. (M)
, pp. 1437-1450
-
-
Steinfeld, A.S.1
Naider, F.2
Becker, J.M.3
-
18
-
-
0024589767
-
Rapid and efficient synthesis of nucleoside 5'-O-(1-thiotriphosphates), 5'-triphosphates and 2',3'-cyclophosphorothioates using 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one
-
Ludwig, J.; Eckstein, F. Rapid and efficient synthesis of nucleoside 5'-O-(1-thiotriphosphates), 5'-triphosphates and 2',3'-cyclophosphorothioates using 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one. J. Org. Chem. 1989, 54, 631-635.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 631-635
-
-
Ludwig, J.1
Eckstein, F.2
-
19
-
-
0025362229
-
Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1
-
Schinazi, R. F.; Sommadossi, J.-P.; Saalmann, V.; Cannon, D. L.; Xie, M.-Y.; Hart, G. C.; Smith, G. A.; Hahn, E. F. Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 1990, 34, 1061-1067.
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 1061-1067
-
-
Schinazi, R.F.1
Sommadossi, J.-P.2
Saalmann, V.3
Cannon, D.L.4
Xie, M.-Y.5
Hart, G.C.6
Smith, G.A.7
Hahn, E.F.8
-
20
-
-
0024524515
-
A short and stereoselective synthesis of (±)-aristeromycin
-
Hutchinson, A.; Grim, M.; Chen, J. A short and stereoselective synthesis of (±)-aristeromycin. J. Heterocycl. Chem. 1989, 26, 451-452.
-
(1989)
J. Heterocycl. Chem.
, vol.26
, pp. 451-452
-
-
Hutchinson, A.1
Grim, M.2
Chen, J.3
-
21
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou, T.-C.; Talalay, P. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 1984, 22, 27-55.
-
(1984)
Adv. Enzyme Regul.
, vol.22
, pp. 27-55
-
-
Chou, T.-C.1
Talalay, P.2
-
22
-
-
0028003745
-
Multiple drug effect analysis with confidence interval
-
Belen'kii, M. S.; Schinazi, R. F. Multiple drug effect analysis with confidence interval. Antiviral Res. 1994, 25, 1-11.
-
(1994)
Antiviral Res.
, vol.25
, pp. 1-11
-
-
Belen'kii, M.S.1
Schinazi, R.F.2
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