Non-homologous Recombination of Deoxyribonucleoside Kinases from Human and Drosophila melanogaster Yields Human-like Enzymes with Novel Activities

Journal of Molecular Biology

Volumn 370, Issue 4, 2007, Pages 742-751

  Gerth, Monica L ^a   Lutz, Stefan ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

enzyme engineering; kinase; nucleoside analog

Indexed keywords

2 FLUORO 9ALPHA DEXTRO ARABINOFURANOSYLADENINE; 2',3' DIDEOXYTHYMIDINE; ACICLOVIR; ADENINE DERIVATIVE; CHIMERIC PROTEIN; DEOXYRIBONUCLEOSIDE KINASE; DIDANOSINE; GANCICLOVIR; GEMCITABINE; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; PEPTIDE LIBRARY; PHOSPHOTRANSFERASE; PRODRUG; PYRIMIDINE; STAVUDINE; THYMIDINE KINASE 2; UNCLASSIFIED DRUG; ZALCITABINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; GENETIC RECOMBINATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN FAMILY; SEQUENCE HOMOLOGY;

DROSOPHILA MELANOGASTER;

EID: 34249939115     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.05.021     Document Type: Article

References (34)

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